onkologi

BACKGROUND: The global health burden of breast cancer is increasing with 5-year survival rates being much shorter in low-income and middle-income countries. Sociodemographic and clinical disparities in early cancer detection affect long-term outcome. METHODS: The authors compared social, demographic, and pathological characteristics associated with metastatic and late stages of breast cancer diagnosis using data collected from a special registry developed by Perhimpunan Bedah Onkologi Indonesia (PERABOI) in 2015...

No abstract text is available yet for this article.

BACKGROUND: Testicular germ cell tumours (GCTs) are the most frequent solid malignancy in younger males aged 15-40. The differentiation between seminomas and non-seminomas impacts prognosis, clinical management and follow-up procedures. With stage- and risk-adapted multimodal treatment approaches, GCTs have an exceptionally good prognosis. Therefore, avoiding overtreatment to reduce treatment-related long-term side effects is of utmost importance. Clinical and histopathological risk factors aid in treatment decision-making...

Background: Lymphoma cells are highly radiosensitive and consequently, radiation therapy is a rational addition to systemic therapy in the treatment of leukemia. Especially as a conditioning regimen before allogeneic stem cell transplantation, radiation therapy, in the form of total body irradiation, is an established concept. Objectives: The present work provides an overview on the execution and side effects of radiation treatment in leukemia. Especially (long-term) side effects after total body irradiation are presented...

No abstract text is available yet for this article.

Patients with cancer are at increased risk of infection due to disease-associated or therapy-induced immunosuppression. Taking into account globally increasing antimicrobial resistance rates and negative effects associated with antibiotic treatments, the effective, appropriate and guideline-conform use of anti-infectives must be promoted in this clinical setting. The application of antibacterial prophylaxis should be limited to high-risk patients. Infection diagnostics and therapeutic strategies differ depending on the extent of expected immunosuppression and the patient's individual risk factors...

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

No abstract text is available yet for this article.

BACKGROUND: Chronic infection with the hepatitis B virus (HBV) is an important risk factor for the development of hepatocellular carcinoma (HCC). Even though treatment options for HCC are constantly improving, preventive measures must not be neglected. CONCLUSION: The vaccination against hepatitis B has proven effective in preventing infection with HBV. As shown more than 20 years ago in Taiwan, vaccination programs lower not only the prevalence of HBsAg carriers but also decrease the incidence of HCC...

Cancer-related fatigue (CRF) is a common, burdensome, debilitating subjective sense of tiredness or exhaustion in patients with cancer. The pathogenesis is assumed to be multifactorial with CRF being a final common pathway. Among other things, treatment with immune checkpoint inhibitors (ICI) is also associated with CRF. However, the toxic adverse events of ICI are not inevitably the only cause for CRF. Therefore, the diagnostic procedure should address other possible influencing factors, e.g., somatic, mental, cognitive, and psychosocial causes...

BACKGROUND: The regularly published quality reports of the haemato-oncology specialist practices primarily include billing data and results of patient and staff surveys as well as current project-related results. In order to obtain further information on structural quality, an additional survey was conducted among haemato-oncology practices. OBJECTIVES: The goals are the analysis and presentation of structural quality characteristics of haemato-oncology specialist practices...

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With the aim of better understanding the enabling and limiting factors regarding staying or returning to work for cancer patients and to test specific measures of support, advisory and survey projects took place at the Robert Bosch Hospital in Stuttgart (RBK), the National Centre for Tumor Diseases in Heidelberg (NCT) as well as partly on behalf of and in cooperation with the Working Group Social Work in Oncology (ASO) of the German Cancer Society e. V. All projects have shown that the problems of career (re)integration faced by cancer patients in treatment, therapy and aftercare need to be taken more into account, as they play an essential role in securing the livelihood of and managing the stress experienced by the patient...

BACKGROUND: During the current pandemic situation, the public health care system must ensure the ongoing provision of regular medical care as well as the treatment of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infected patients. Resident oncologists and their practices are equally affected. OBJECTIVES: The study examines resident oncologists' challenges, experiences and approaches in the delivery of care for oncological patients receiving palliative treatment and their relatives during the pandemic...

Patients with cancer are at an increased risk to suffer severe coronavirus disease 2019 (COVID-19). Therefore, specific preventative measures including COVID-19 vaccines are especially important. Both anticancer therapies and the underlying malignancy itself can lead to significant immunosuppression posing a particular challenge for vaccination strategies in these patients. At the moment, four COVID-19 vaccines are European Medicines Agency (EMA) approved in Germany: two mRNA and two viral vector-based vaccines...

BACKGROUND: The German healthcare system is facing unprecedented challenges due to the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) pandemic. Palliative care for critically ill patients and their families was also severely compromised, especially during the first wave of the pandemic, in both inpatient and outpatient settings. MATERIALS AND METHODS: The paper is based on our experience in routine inpatient palliative care and partial results of a study conducted as part of the collaborative project "National Strategy for Palliative Care in Pandemic Times (PallPan)"...

BACKGROUND: Survivorship care programs (SCP) are increasingly being implemented in order to ensure long-term and comprehensive care of physical and psychosocial cancer-related sequelae among survivors. In this article, we provide a short overview of SCP and the importance of health-related self-management. RESULTS: The broad definition of "survivorship" and the high diversity of impairments among cancer survivors warrants a personalized and multidimensional approach...

Chemotherapy treatment often causes side-effects like fatigue in cancer patients. The treatment and diagnosis of cancer can cause depression, which could lead to inflammatory changes in the body, and it is involved in fatigue pathophysiology. This study aims to determine the relationship between depression and fatigue. A cross-sectional design was used, and a consecutive sampling method with a sample of 30 children with cancer aged 8-12 years. This study used two instruments, which are the Fatigue Onkologi Anak-Allen (FOA-A) questionnaire and Centre for Epidemiological Studies Depression Scale for Children (CES-DC)...