keyword
https://read.qxmd.com/read/38536956/integrated-in-situ-fabrication-of-cuo-nanorod-decorated-polymer-membranes-for-the-catalytic-flow-through-reduction-of-p-nitrophenol
#1
JOURNAL ARTICLE
S Amir H Hesaraki, Oleg Prymak, Markus Heidelmann, Mathias Ulbricht, Lukas Fischer
We developed a novel method to fabricate copper nanorods in situ in a poly(ether sulfone) (15 wt %) casting solution by a sonochemical reduction of Cu2+ ions with NaBH4 . The main twist is the addition of ethanol to remove excess NaBH4 through Cu(0) catalyzed ethanolysis. This enabled the direct use of the resulting copper-containing casting dispersions for membrane preparation by liquid nonsolvent-induced phase separation and led to full utilization of the copper source, generating zero metal waste. We characterized the copper nanorods as presented in the membranes via scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and UV/vis spectroscopy...
March 27, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38536783/autophagosome-biogenesis-and-organelle-homeostasis-in-plant-cells
#2
JOURNAL ARTICLE
Xiaohong Zhuang, Baiying Li, Liwen Jiang
Autophagy is one of the major highly inducible degradation processes in response to plant developmental and environmental signals. In response to different stimuli, cellular materials, including proteins and organelles, can be sequestered into a double membrane autophagosome structure either selectively or non-selectively. The formation of an autophagosome as well as its delivery into the vacuole involves complex and dynamic membrane processes. The identification and characterization of the conserved autophagy-related (ATG) proteins and their related regulators have greatly advanced our understanding of the molecular mechanism underlying autophagosome biogenesis and function in plant cells...
March 27, 2024: Plant Cell
https://read.qxmd.com/read/38536671/evaluating-a-promising-methylcellulose-hydrogel-for-enhanced-diabetic-foot-ulcer-therapy-through-comprehensive-preclinical-studies
#3
JOURNAL ARTICLE
Priya Patel, Sanika Dongre, Alkesh Patel, Gayatri Patel
The present research focuses on formulating and evaluating hydrogels modified with crosslinking agents using methylcellulose to treat diabetic foot ulcers (DFU). Methylcellulose hydrogels are prepared and characterized for their crosslinking capacity through FTIR and degradation studies. The optimized hydrogel is further assessed for viscosity, gel strength, contact angle, in-vitro biodegradation, water-vapor transmission rate, anti-bacterial activity, and in-vivo efficacy. The results demonstrate that the developed hydrogel exhibits promising properties for DFU treatment, including increased wound healing percentage, improved ulcer morphology, reduced levels of proinflammatory cytokines, and enhanced tissue characteristics...
March 27, 2024: Journal of Biomaterials Science. Polymer Edition
https://read.qxmd.com/read/38535943/the-influence-of-textile-type-textile-weight-and-detergent-dosage-on-microfiber-emissions-from-top-loading-washing-machines
#4
JOURNAL ARTICLE
Pongsiri Julapong, Palot Srichonphaisarn, Thidarat Meekoch, Carlito Baltazar Tabelin, Onchanok Juntarasakul, Theerayut Phengsaart
The use of washing machines to wash textiles gradually breaks down synthetic fibers like polyethylene terephthalate (PET) or polyester (PES) in diverse clothing materials, a process that is growing in notoriety because it generates microplastics (MPs). In this study, we investigated the emission of microfibers, including both microplastic fibers (MPFs) and natural fibers (MFs), from top-loading washing machines. Our investigation focused on four popular textiles with prevalent weave structures (plain, satin, and twill): (i) PES, (ii) tetron cotton (TC), (iii) chief value cotton (CVC), and (iv) cotton (CO) fabrics...
March 12, 2024: Toxics
https://read.qxmd.com/read/38535752/extending-the-lifetime-of-vanadium-redox-flow-batteries-by-reactivation-of-carbon-electrode-materials
#5
JOURNAL ARTICLE
Muhammad Adeel Ashraf, Stylianos Daskalakis, Matthias Kogler, Markus Ostermann, Soniya Gahlawat, Seohee Son, Pavel Mardilovich, Markus Valtiner, Christian M Pichler
The degradation and aging of carbon felt electrodes is a main reason for the performance loss of Vanadium Redox Flow Batteries over extended operation time. In this study, the chemical mechanisms for carbon electrode degradation are investigated and distinct differences in the degradation mechanisms on positive and negative electrodes have been revealed. A combination of surface analysis techniques such as X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, and Electrochemical Impedance Spectroscopy (EIS) was applied for this purpose...
March 27, 2024: Nanoscale
https://read.qxmd.com/read/38535701/exploring-the-application-of-graphene-oxide-based-nanomaterials-in-the-repair-of-osteoporotic-fractures
#6
REVIEW
Hongfa Zhou, Jinyuan Chen, Xuan Zhang, JingJing Chen, Jiayou Chen, Shicheng Jia, Deli Wang, Hui Zeng, Jian Weng, Fei Yu
Osteoporotic fractures are induced by osteoporosis, which may lead to the degradation of bone tissues and microstructures and impair their healing ability. Conventional internal fixation therapies are ineffective in the treatment of osteoporotic fractures. Hence, developing tissue engineering materials is crucial for repairing osteoporotic fractures. It has been demonstrated that nanomaterials, particularly graphene oxide (GO), possess unique advantages in tissue engineering due to their excellent biocompatibility, mechanical properties, and osteoinductive abilities...
March 21, 2024: Nanomaterials
https://read.qxmd.com/read/38535673/a-3d-printed-portable-uv-and-visible-photoreactor-for-water-purification-and-disinfection-experiments
#7
JOURNAL ARTICLE
Nelson Castro, Joana M Queirós, Dinis C Alves, Margarida M Macedo Fernandes, Senetxu Lanceros-Méndez, Pedro M Martins
Water scarcity and contamination are urgent issues to be addressed. In this context, different materials, techniques, and devices are being developed to mitigate contemporary and forthcoming water constraints. Photocatalysis-based approaches are suitable strategies to address water contamination by degrading contaminants and eliminating microbes. Photoreactors are usually designed to perform photocatalysis in a scalable and standardised way. Few or none have been developed to combine these characteristics with portability, flexibility, and cost effectiveness...
March 15, 2024: Nanomaterials
https://read.qxmd.com/read/38535609/regulation-of-autophagosome-lysosome-fusion-by-human-viral-infections
#8
REVIEW
Po-Yuan Ke
Autophagy plays a fundamental role in maintaining cellular homeostasis by eliminating intracellular components via lysosomes. Successful degradation through autophagy relies on the fusion of autophagosomes to lysosomes, which leads to the formation of autolysosomes containing acidic proteases that degrade the sequestered materials. Viral infections can exploit autophagy in infected cells to balance virus-host cell interactions by degrading the invading virus or promoting viral growth. In recent years, cumulative studies have indicated that viral infections may interfere with the fusion of autophagosomes and lysosomes, thus benefiting viral replication and associated pathogenesis...
March 20, 2024: Pathogens
https://read.qxmd.com/read/38535464/algae-based-supplements-claiming-weight-loss-properties-authenticity-control-and-scientific-based-evidence-on-their-effectiveness
#9
JOURNAL ARTICLE
Fátima Fernandes, Raquel Martins, Mariana Barbosa, Patrícia Valentão
The worldwide prevalence of obesity impacts more than 600 million adults. Successfully managing weight is effective in reducing the risk of chronic diseases, but sustaining long-term weight loss remains a challenge. Although there are supplements based on algae that claim to aid in weight loss, there is a notable scarcity of scientific evidence supporting their effectiveness, and their regular consumption safety remains inadequately addressed. In this work, commercially available Arthrospira (Spirulina) platensis Gomont and/or Fucus vesiculosus L...
March 5, 2024: Marine Drugs
https://read.qxmd.com/read/38535272/advancements-in-biomedical-applications-of-calcium-phosphate-glass-and-glass-based-devices-a-review
#10
REVIEW
Jawad T Pandayil, Nadia G Boetti, Davide Janner
Calcium phosphate (CaP) glass has recently gained popularity as a promising material for a wide range of biomedical applications. Recent developments have seen CaP glasses moving from a passive implant material to an active degradable material, particularly as a major constituent of bioresorbable photonic devices. This holds great promise in advanced biomedical applications, since the main constituents of CaP glasses are present in the human body. In this review, the progressive advancements in the biomedical applications of calcium phosphate glass-based devices over the past 50 years are discussed...
March 21, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38535255/hybrid-coatings-based-on-polyvinylpyrrolidone-polyethylene-glycol-enriched-with-collagen-and-hydroxyapatite-incubation-studies-and-evaluation-of-mechanical-and-physiochemical-properties
#11
JOURNAL ARTICLE
Dagmara Słota, Josef Jampilek, Agnieszka Sobczak-Kupiec
Coating materials offers an intriguing solution for imparting inert implants with additional bioactive characteristics without changing underlying parameters such as mechanical strength. Metallic implants like endoprostheses or polymeric implants can be coated with a thin layer of bioactive film capable of stimulating bone-forming cells to proliferate or release a drug. However, irrespective of the final implantation site of such a coating biomaterial, it is necessary to conduct detailed mechanical and physicochemical in vitro analyses to determine its likely behavior under biological conditions...
March 1, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38535250/characterization-and-in-vitro-evaluation-of-porous-polymer-blended-scaffolds-functionalized-with-tricalcium-phosphate
#12
JOURNAL ARTICLE
Iwona Pudełko-Prażuch, Mareeswari Balasubramanian, Sundara Moorthi Ganesan, Stanisław Marecik, Kamila Walczak, Kinga Pielichowska, Suvro Chatterjee, Ravichandran Kandaswamy, Elżbieta Pamuła
Bone tissue is one of the most transplanted tissues. The ageing population and bone diseases are the main causes of the growing need for novel treatments offered by bone tissue engineering. Three-dimensional (3D) scaffolds, as artificial structures that fulfil certain characteristics, can be used as a temporary matrix for bone regeneration. In this study, we aimed to fabricate 3D porous polymer scaffolds functionalized with tricalcium phosphate (TCP) particles for applications in bone tissue regeneration. Different combinations of poly(lactic acid) (PLA), poly(ethylene glycol) (PEG with molecular weight of 600 or 2000 Da) and poly(ε-caprolactone) (PCL) with TCP were blended by a gel-casting method combined with rapid heating...
February 26, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38535248/generation-of-pearl-calcium-phosphate-composite-particles-and-their-integration-into-porous-chitosan-scaffolds-for-bone-regeneration
#13
JOURNAL ARTICLE
Zhiyi Li, Ihtesham Ur Rehman, Rebecca Shepherd, Timothy E L Douglas
Bone tissue engineering using osteoconductive scaffolds holds promise for regeneration, with pearl powder gaining interest for its bioactive qualities. This study used freeze drying to create chitosan (CS) scaffolds with pearl/calcium phosphate (p/CaP) powders, mimicking bone tissue structurally and compositionally. Characterization included scanning electron microscopy (SEM) and mechanical testing. X-ray diffraction (XRD) Fourier-transform infrared-photoacoustic photo-acoustic sampling (FTIR-PAS), and FTIR- attenuated total reflectance (FTIR-ATR) were used to characterize p/CaP...
February 21, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38535245/influence-of-hybrid-surface-modification-on-biocompatibility-and-physicochemical-properties-of-ti-6al-4v-eli-titanium
#14
JOURNAL ARTICLE
Anna Woźniak, Weronika Smok, Janusz Szewczenko, Marcin Staszuk, Grzegorz Chladek
Titanium-based materials are the most widely used materials in biomedical applications. However, according to literature findings, the degradation products of titanium have been associated with potential allergic reactions, inflammation, and bone resorption. The corrosion process of Ti-6Al-4V in the human body environment may be exacerbated by factors such as reduced pH levels and elevated concentrations of chloride compounds. Coatings made of biopolymers are gaining attention as they offer numerous advantages for enhancing implant functionality, including improved biocompatibility, bioactivity, wettability, drug release, and antibacterial activity...
February 20, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38535173/the-dynamic-interaction-between-oil-palm-and-phytophthora-palmivora-in-bud-rot-disease-insights-from-transcriptomic-analysis-and-network-modelling
#15
JOURNAL ARTICLE
Mariandrea García-Gaona, David Botero-Rozo, Leonardo Araque, Hernán Mauricio Romero
Bud Rot, caused by Phytophthora palmivora , is considered one of the main diseases affecting African oil palm ( Elaeis guineensis ). In this study, we investigated the in vitro molecular dynamics of the pathogen-host interaction by analyzing gene expression profiles from oil palm genotypes that were either susceptible or resistant to the disease. We observed distinct interactions of P. palmivora with resistant and susceptible oil palms through co-expression network analysis. When interacting with susceptible genotypes, P...
February 20, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38534915/effect-of-chitosan-degradation-products-glucosamine-and-chitosan-oligosaccharide-on-osteoclastic-differentiation
#16
JOURNAL ARTICLE
Tomoharu Takeuchi, Midori Oyama, Tomomi Hatanaka
Chitosan, a natural cationic polysaccharide derived from crustaceans and shellfish shells, is known for its advantageous biological properties, including biodegradability, biocompatibility, and antibacterial activity. Chitosan and its composite materials are studied for their potential for bone tissue repair. However, the effects of chitosan degradation products, glucosamine (GlcN) and chitosan oligosaccharide (COS), on osteoclasts remain unclear. If these chitosan degradation products promote osteoclastic differentiation, careful consideration is required for the use of chitosan and related materials in bone repair applications...
March 6, 2024: BioTech (Basel)
https://read.qxmd.com/read/38534865/snake-robot-with-motion-based-on-shape-memory-alloy-spring-shaped-actuators
#17
JOURNAL ARTICLE
Ricardo Cortez, Marco Antonio Sandoval-Chileño, Norma Lozada-Castillo, Alberto Luviano-Juárez
This study presents the design and evaluation of a prototype snake-like robot that possesses an actuation system based on shape memory alloys (SMAs). The device is constructed based on a modular structure of links connected by two degrees of freedom links utilizing Cardan joints, where each degree of freedom is actuated by an agonist-antagonist mechanism using the SMA spring-shaped actuators to generate motion, which can be easily replaced once they reach a degradation point. The methodology for programming the spring shape into the SMA material is described in this work, as well as the instrumentation required for the monitoring and control of the actuators...
March 16, 2024: Biomimetics
https://read.qxmd.com/read/38534630/tailoring-hydrogel-structures-investigating-the-effects-of-multistep-cellulose-defibrillation-on-polyvinyl-alcohol-composites
#18
JOURNAL ARTICLE
Gabriel Goetten de Lima, Bruno Bernardi Aggio, Alessandra Cristina Pedro, Tielidy A de M de Lima, Washington Luiz Esteves Magalhães
Defibrillating cellulose through various grinding steps and incorporating it into hydrogels introduces unique properties that warrant thorough exploration. This study investigates cellulose defibrillation at different steps (15-120) using an ultra-fine friction grinder, blended with high-molecular-weight polyvinyl alcohol (PVA), and crosslinked via freeze-thawing. A critical discovery is the influence of defibrillation on the hydrogel structure, as evidenced by reduced crystallinity, thermal degradation, and the enhanced swelling of PVA chains...
March 21, 2024: Gels
https://read.qxmd.com/read/38534345/molecular-mechanism-of-autophagosome-lysosome-fusion-in-mammalian-cells
#19
REVIEW
Po-Yuan Ke
In eukaryotes, targeting intracellular components for lysosomal degradation by autophagy represents a catabolic process that evolutionarily regulates cellular homeostasis. The successful completion of autophagy initiates the engulfment of cytoplasmic materials within double-membrane autophagosomes and subsequent delivery to autolysosomes for degradation by acidic proteases. The formation of autolysosomes relies on the precise fusion of autophagosomes with lysosomes. In recent decades, numerous studies have provided insights into the molecular regulation of autophagosome-lysosome fusion...
March 13, 2024: Cells
https://read.qxmd.com/read/38534311/glycogen-granules-are-degraded-by-non-selective-autophagy-in-nitrogen-starved-komagataella-phaffii
#20
JOURNAL ARTICLE
Nimna V Wijewantha, Ravinder Kumar, Taras Y Nazarko
Autophagy was initially recognized as a bulk degradation process that randomly sequesters and degrades cytoplasmic material in lysosomes (vacuoles in yeast). In recent years, various types of selective autophagy have been discovered. Glycophagy, the selective autophagy of glycogen granules, is one of them. While autophagy of glycogen is an important contributor to Pompe disease, which is characterized by the lysosomal accumulation of glycogen, its selectivity is still a matter of debate. Here, we developed the Komagataella phaffii yeast as a simple model of glycogen autophagy under nitrogen starvation conditions to address the question of its selectivity...
March 7, 2024: Cells
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