Lingfeng Guan, Xiaozhi Wen, Zihan Zhang, Liqun Wang, Xinyue Zhang, Min Yang, Shaowen Wang, Qiwei Qin
Rab1, a GTPase, is present in all eukaryotes, and is mainly involved in vesicle trafficking between the endoplasmic reticulum and Golgi, thereby regulating many cellular activities and pathogenic infections. However, little is known of how Rab1 functions in fish during virus infection. Groupers (Epinephelus spp.) are high in economic value and widely cultivated in China and Southeast Asia, although they often suffer from diseases. Red-spotted grouper nervous necrosis virus (RGNNV), a highly pathogenic RNA virus, is a major pathogen in cultured groupers, and causes huge economic losses...
October 13, 2023: Fish & Shellfish Immunology