keyword
https://read.qxmd.com/read/37786129/sub-grouping-strategy-for-improving-atlas-based-segmentation-performance
#21
JOURNAL ARTICLE
B Wang
PURPOSE/OBJECTIVE(S): Multi-atlas based segmentation (MAS) uses the prior knowledge provided by finding the best fitting images contoured previously and then propagate the delineation in the atlas onto the target image. However, in the contour propagation approach, grayscale-based similarity metric does not always properly find the best fitting of the registered atlas image and the corresponding segmentation. This is mainly due to the selection calculated similarity of entire images rather than adjacent area of contours...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37786111/evaluation-of-a-deep-learning-auto-segmentation-model-of-cardiac-substructures
#22
JOURNAL ARTICLE
A Tam, J R Liu, T Ketcherside, N J Eustace, Q Chen, Y J Chen, A Liu
PURPOSE/OBJECTIVE(S): Increasing evidence has suggested that limiting dose not only to the whole heart but also to cardiac substructures can potentially reduce cardiac toxicities. Manual contouring of cardiac substructure can be challenging and time-consuming. To address this concern, we developed a deep learning (DL) model, trained on convolutional neural network algorithms in large external datasets, for auto-segmentation of cardiac substructures. This study aimed to evaluate the quality of the cardiac substructure contours generated by the DL algorithm...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37786081/evaluation-of-a-deep-image-to-image-network-di2in-auto-segmentation-algorithm-across-a-network-of-cancer-centers
#23
JOURNAL ARTICLE
K Rayn, V Gupta, S Mulinti, R Clark, A Magliari, S Chaudhari, G Gokhroo, S Beriwal
PURPOSE/OBJECTIVE(S): Due to manual OAR contouring challenges, various automatic contouring solutions have been introduced. Historically, common clinical auto-segmentation algorithms used were atlas based, which required maintaining a library of self-made contours. Searching the collection was computationally intensive and could take several minutes to complete. Deep learning approaches have shown significant benefits compared to atlas-based methods in improving segmentation accuracy and efficiency in auto-segmentation algorithms...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37786079/pelvic-nodal-auto-segmentation-using-a-deep-image-to-image-network-di2in-auto-segmentation-algorithm-comparing-male-vs-female-pelvis
#24
JOURNAL ARTICLE
K Rayn, G Gokhroo, V Gupta, S Chaudhari, R Clark, A Magliari, S Beriwal
PURPOSE/OBJECTIVE(S): Deep Learning approaches have shown significant benefits compared to atlas-based methods in improving segmentation accuracy and efficiency in auto-segmentation algorithms. The AI-Rad Companion Organs RT pelvic nodal auto-segmentation feature was trained and developed for use in the male pelvis. There is no real-world data on its usability in male pelvis and whether it can be used for female pelvic nodal anatomy. This work represents the first multi-institutional study to describe and evaluate an AI algorithm for auto-segmentation of the pelvic nodal region in female patients based on a deep image-to-image network (DI2IN)...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785908/the-effect-of-deep-inspiration-breath-hold-technique-on-right-coronary-artery-heart-and-liver-doses-in-right-breast-cancer-radiotherapy
#25
JOURNAL ARTICLE
V Semiz, B Aydin, D Gulsan, E Atac, E Ozkaya, S Kinay, D Akcay, R Kandemir, M Can, I B Gorken
PURPOSE/OBJECTIVE(S): The deep inspiration breath-hold (DIBH) approach has been thoroughly researched with the aim of reducing radiation exposures to normal tissues in breast cancer patients. Although heart and lung toxicity are widely addressed in many literature, radiation-associated liver toxicity and dose constraints for the right coronary artery (RCA) are not well studied in relation to breast radiotherapy. Additionally, very few studies have investigated the relationship between doses to cardiac substructures...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785664/enhancing-specialist-training-in-radiation-oncology-through-the-implementation-of-structured-radiotherapy-contouring-workshops
#26
JOURNAL ARTICLE
G Rangaswamy, J Nicholson, N Wallace, E Connolly, O Houlihan, O Monaghan, J Trousdell, C Skourou, C Rohan, D Foley, F K Duane, B D O'Neill, P Thirion, M Cunningham, S M Brennan, O McArdle
PURPOSE/OBJECTIVE(S): Contouring tumor volumes and organs at risk is a key component of Radiation Oncology specialist training. As trainees rotate through different tumor sites, they are expected to develop proficiency in contouring skills relevant to their year of training. These skills have historically been acquired in an unstructured manner during supervised clinical work. However, trainees often struggle to learn these skills due to variability in practice and approach amongst senior colleagues...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785536/developing-an-online-interactive-volumetric-surface-viewer-for-visualizing-spatial-distribution-of-intracranial-lesions
#27
JOURNAL ARTICLE
R R Savjani, W Delery, T M Ma, S E Tenn, T B Kaprealian, J V Hegde
PURPOSE/OBJECTIVE(S): The exact location of intracranial neoplasms and metastatic lesions within the cortex may provide key insights into predicting treatment effectiveness and toxicities. Modern neuroimaging approaches have enabled precise, rapid diffeomorphic alignment from individual brains to an atlas, allowing the registration of contours and dose distributions onto a common template. However, there is a paucity of intuitive tools to perform such functions. Here, we developed an online interactive volumetric surface viewer that displays distribution of brain lesions of specific clinical features within the context of prior radiation treatment in populations of patients on a common atlas...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785534/an-innovative-approach-to-scalp-segmentation-in-pediatric-brain-radiotherapy-an-atlas-based-study
#28
JOURNAL ARTICLE
C Satragno, M Barboro, A Alparone, G Fiorella, M Turazzi, S Campora, S E Cena, A Coco, D Esposito, A Ferrero, A Ginulla, S Mastrogiovanni, F Piciche, C Scaffidi, C Tominai, F Cavagnetto, D Zefiro, F Giannelli, S Barra, L Belgioia
PURPOSE/OBJECTIVE(S): This study aims to develop an atlas-based method for segmentation of the scalp in pediatric patients that received brain radiotherapy. The study focuses on the development of a model that utilizes CT scans of pediatric medulloblastoma (MB) patients who underwent craniospinal-irradiation (CSI) and a boost in the posterior cranial fossa (PCF). MATERIALS/METHODS: A team of experts created the Alopecia_Hope (A_H) contouring protocol on the CT scan using the 2018 EPTN consensus-based atlas and by defining for the manual adjustments the anatomic bone landmarks to differentiate between the scalp and the facial and neck skin...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785468/clinical-implementation-and-evaluation-of-automated-contouring-for-breast-malignancies
#29
JOURNAL ARTICLE
A Bonner, R Travis, C Cardenas, M Soike, H Boggs
PURPOSE/OBJECTIVE(S): As breast radiotherapy becomes more conformal, precise target delineation is increasingly important. Multiple atlases are available to provide uniformity, but contouring remains resource intensive and prone to variation. Automated contouring has been investigated to reduce planning time and standardize contouring practices. Herein, we investigate a model trained to autocontour RADCOMP breast regional nodal targets using a small, highly curated set of manual contours...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785258/dce-mri-based-atlas-for-prostate-bed-recurrence-after-radical-prostatectomy-consistency-of-ctv-delineation-with-the-available-contouring-guidelines
#30
JOURNAL ARTICLE
M Bottero, I Avanzolini, S Marzi, V Landoni, A Faiella, P D'Urso, A Farneti, G Facondo, A Soriani, G Sanguineti
PURPOSE/OBJECTIVE(S): To create a magnetic resonance image (MRI)-based atlas of prostate bed recurrence for prostate cancer patients undergoing salvage radiotherapy (sRT) after radical prostatectomy and to evaluate the consistency of contouring guidelines for the prostatic fossa clinical target volume (PF-CTV) delineation. MATERIALS/METHODS: Patients with biochemical recurrence and prostate bed lesions at MRI before sRT were included. A reference patient was identified and the lesion(s) of each patient was mapped by a deformable co-registration among T2 weighted (T2w) images...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785195/dosimetric-evaluation-of-cardiac-substructures-in-irradiation-of-esophagus
#31
JOURNAL ARTICLE
A Tam, C Wong, J R Liu, N J Eustace, T Ketcherside, A Liu, Y J Chen
PURPOSE/OBJECTIVE(S): Due to the anatomic proximity of the heart, cardiac toxicity is a major concern in radiation treatment (RT) of esophageal cancer. Historically, the entire heart is considered an organ at risk. However, more recent studies have demonstrated that dose to cardiac substructures may better predict cardiac toxicities. We retrospectively reviewed patients (pts) who had RT to the distal esophagus and evaluated the dose-volume constraints (DVCs) of the cardiac substructures and the whole heart...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785058/patterns-of-locoregional-pancreatic-cancer-recurrence-after-total-neoadjuvant-therapy-and-implications-on-optimal-neoadjuvant-radiation-treatment-volumes
#32
JOURNAL ARTICLE
S E Beltran Ponce, C J Small, T Ahmad, K Patel, S Tsai, M Kamgar, B George, J R Kharofa, H Saeed, K S Dua, C Clarke, M Aldakkak, D B Evans, K Christians, E S Paulson, S Ortiz de Choudens, B A Erickson, W A Hall
PURPOSE/OBJECTIVE(S): Neoadjuvant treatment for patients with localized pancreatic adenocarcinoma (PDAC) has improved survival duration. As survival increases, local disease control becomes even more important. We sought to understand the patterns of locoregional recurrence following total neoadjuvant therapy (TNT) and determine the impact of treatment volumes on recurrence. MATERIALS/METHODS: Patients with PDAC managed with neoadjuvant chemotherapy and chemoradiation (TNT) followed by surgery who developed an isolated locoregional or simultaneously locoregional and distant recurrence were identified...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37785020/sinoatrial-node-irradiation-in-patients-undergoing-definitive-stereotactic-body-radiation-therapy-sbrt-for-central-lung-cancers
#33
JOURNAL ARTICLE
A J Iovoli, H Yu, P G Advani, H Malhotra, S Fung-Kee-Fung, N K Malik, A K Singh, M K Farrugia
PURPOSE/OBJECTIVE(S): The clinical consequences of sinoatrial node (SAN) and atrioventricular node (AVN) irradiation in patients undergoing thoracic stereotactic body radiation therapy (SBRT) remains unclear. We examined the relationship between SAN and AVN dose with survival outcomes in patients with central non-small cell lung cancer (NSCLC) tumors. MATERIALS/METHODS: A single-institutional retrospective review of patients with primary NSCLC undergoing definitive SBRT for centrally located tumors from February 2007 to December 2021 was performed...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784852/a-radiation-therapy-contouring-atlas-for-delineation-of-the-level-i-ii-axilla-in-the-prone-position
#34
JOURNAL ARTICLE
J Purswani, E Goldberg, O Cahlon, F Schnabel, D Axelrod, A Guth, C A Perez, F Shaikh, M Tam, S C Formenti, B Reig, N K Gerber
PURPOSE/OBJECTIVE(S): When patients are treated prone for whole breast irradiation (WBI), the axilla typically receives less dose than when patients are treated with WBI in the supine position. There are situations, however, where the axilla is a target as in a situation where the physician intends to treat with "high tangents" to provide good coverage of both the breast and level I-II axilla. In these scenarios, ideal target delineation when the patient is in the prone position is not well-defined...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784788/one-year-follow-up-and-toxicity-review-in-a-series-of-6-patients-receiving-stereotactic-arrhythmia-radioablation-for-ventricular-tachycardia
#35
JOURNAL ARTICLE
I J Gerard, V Anglesio, M L Bernier, T Hijal, S Konermann, N Kopek, P Pater, G Stroian, B Toscani Gomes Da Si, J Alfieri
PURPOSE/OBJECTIVE(S): Stereotactic body radiation therapy (SBRT) to arrhythmogenic scar regions defined by noninvasive cardiac mapping has recently been described for patients with treatment refractory ventricular tachycardia (VT). Long-term outcomes and both intra- and extra-cardiac toxicities are not well described in this patient population. We report the outcomes following at least 1-year post-treatment along with toxicity for 6 patients treated with this technique in our institution...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784653/a-pilot-study-of-simulation-free-hippocampal-avoidance-whole-brain-radiotherapy-using-diagnostic-mr-based-and-online-adaptive-planning
#36
JOURNAL ARTICLE
K H Kang, A T Price, F J Reynoso, E Laugeman, E D Morris, P Samson, J Huang, S N Badiyan, H Kim, R J Brenneman, C D Abraham, N Knutson, L E Henke
PURPOSE/OBJECTIVE(S): We aimed to demonstrate the clinical feasibility and safety of a simulation-free hippocampal avoidance whole brain radiotherapy (HA-WBRT) workflow in a Phase I clinical trial (NCT05096286). Feasibility was defined as successful completion of the simulation-free HA-WBRT workflow through treatment delivery in at last 70% of treated patients. MATERIALS/METHODS: Ten candidates for HA-WBRT were enrolled for treatment on a ring gantry CT-guided Linac with online adaptive capabilities...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784332/integrating-workshop-training-and-artificial-intelligence-ai-to-contour-organs-at-risk-oars-in-thoracic-radiation-therapy
#37
JOURNAL ARTICLE
(no author information available yet)
PURPOSE/OBJECTIVE(S): This work aimed to quantify and explore the effects of expert training and AI on improving the consistency in Organs at Risk (OAR) delineations on the and the concordance to RTOG Atlas for future work of multi-center clinical trials. MATERIALS/METHODS: This is a result of an on-site clinical training workshop/Global Collaborative Oncology Group (GCOG) and an online cross-over study of AI application on key thoracic OARs. The participating experts were provided with the same de-identified cases of stage III Non-Small Cell Lung Cancer (NSCLC) and instructions on structure contouring and plan assessment criteria according to RTOG1106...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37784267/identifying-a-dose-constraint-for-the-parotid-ducts-impact-on-patient-reported-xerostomia-and-comparison-to-conventional-parotid-gland-mean-dose-sparing
#38
JOURNAL ARTICLE
D V Fried, M Ahmidouch, C Shen, S K Das, L B Marks, B S Chera
PURPOSE/OBJECTIVE(S): (1) Identify a dose constraint for the parotid ducts to reduce patient reported xerostomia and compare effectiveness to QUANTEC constraint. (2) Determine if conventionally planned patients meet this constraint by using atlas-based duct segmentation. MATERIALS/METHODS: (1) 38 patients with oropharyngeal squamous cell carcinoma (OPSCC) were treated prospectively on trial with MRI sialography guided parotid duct sparing radiation therapy (parotid duct sparing cohort)...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/37713940/contouring-variation-affects-estimates-of-normal-tissue-complication-probability-for-breast-fibrosis-after-radiotherapy
#39
JOURNAL ARTICLE
Tanwiwat Jaikuna, Eliana Vasquez Osorio, David Azria, Jenny Chang-Claude, Maria Carmen De Santis, Sara Gutiérrez-Enríquez, Marcel van Herk, Peter Hoskin, Maarten Lambrecht, Zoe Lingard, Petra Seibold, Alejandro Seoane, Elena Sperk, R Paul Symonds, Christopher J Talbot, Tiziana Rancati, Tim Rattay, Victoria Reyes, Barry S Rosenstein, Dirk de Ruysscher, Ana Vega, Liv Veldeman, Adam Webb, Catharine M L West, Marianne C Aznar
BACKGROUND: Normal tissue complication probability (NTCP) models can be useful to estimate the risk of fibrosis after breast-conserving surgery (BCS) and radiotherapy (RT) to the breast. However, they are subject to uncertainties. We present the impact of contouring variation on the prediction of fibrosis. MATERIALS AND METHODS: 280 breast cancer patients treated BCS-RT were included. Nine Clinical Target Volume (CTV) contours were created for each patient: i) CTV_crop (reference), cropped 5 mm from the skin and ii) CTV_skin, uncropped and including the skin, iii) segmenting the 95% isodose (Iso95% ) and iv) 3 different auto-contouring atlases generating uncropped and cropped contours (Atlas_skin/Atlas_crop)...
September 11, 2023: Breast: Official Journal of the European Society of Mastology
https://read.qxmd.com/read/37673578/artificial-intelligence-framework-with-traditional-computer-vision-and-deep-learning-approaches-for-optimal-automatic-segmentation-of-left-ventricle-with-scar
#40
JOURNAL ARTICLE
Michail Mamalakis, Pankaj Garg, Tom Nelson, Justin Lee, Andrew J Swift, James M Wild, Richard H Clayton
Automatic segmentation of the cardiac left ventricle with scars remains a challenging and clinically significant task, as it is essential for patient diagnosis and treatment pathways. This study aimed to develop a novel framework and cost function to achieve optimal automatic segmentation of the left ventricle with scars using LGE-MRI images. To ensure the generalization of the framework, an unbiased validation protocol was established using out-of-distribution (OOD) internal and external validation cohorts, and intra-observation and inter-observer variability ground truths...
September 2023: Artificial Intelligence in Medicine
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