Read by QxMD icon Read

contouring atlas

Robert Neil Finnegan, Jason A Dowling, Eng-Siew Koh, Simon Tang, James Otton, Geoff Delaney, Vikneswary Batumalai, Carol Luo, Pramukh Atluri, Athiththa Satchithanandha, David I Thwaites, Lois Holloway
Toxicity to cardiac and coronary structures is an important late morbidity for patients undergoing left-sided breast radiotherapy. Many current studies have relied on estimates of cardiac doses assuming standardised anatomy, with a calculated increase in relative risk of 7.4% per Gy (mean heart dose). To provide individualised estimates for dose, delineation of various cardiac structures on patient images is required. Automatic multi-atlas based segmentation can provide a consistent, robust solution, however, there are challenges to this method...
March 11, 2019: Physics in Medicine and Biology
Meltem Kırlı, Doğukan Akçay, Mustafa Mahmut Barış, İlknur Bilkay Görken
PURPOSE: We developed a heart atlas for breast radiation therapy and evaluated the influence of education on intra and inter-observer similarity, and cardiac dose reporting. MATERIALS AND METHODS: The data of 16 left breast cancer patients were analyzed. Eight observers delineated heart and cardiac subunits [left (LCA) and right (RCA) coronary arteries, left anterior descending artery (LAD), bilateral atrium and ventricles] before the education. A radiologist and radiation oncologist developed the atlas and delineated the gold standard (GS) volumes...
February 18, 2019: Japanese Journal of Radiology
John Leung, Margot Lehman
INTRODUCTION: This paper reports the key findings of the first survey of Australian, New Zealand (ANZ) and Singaporean radiation oncology trainees on contouring and planning. METHODS: The survey was conducted from May to July 2018 using a 35-question instrument. It was emailed to all ANZ and Singaporean trainees on the Royal Australian and New Zealand College of Radiologists (RANZCR) database with at least 6 months experience. The questions related to demographics, time spent on contouring, most difficult sites to contour, most useful atlas, feedback on contouring, interaction with radiation therapists, plan reviews, stereotactic radiation therapy (SBRT), brachytherapy and suggested areas of improvement...
February 5, 2019: Journal of Medical Imaging and Radiation Oncology
Kathleen Gilbert, Wenjia Bai, Charlene Mauger, Pau Medrano-Gracia, Avan Suinesiaputra, Aaron M Lee, Mihir M Sanghvi, Nay Aung, Stefan K Piechnik, Stefan Neubauer, Steffen E Petersen, Daniel Rueckert, Alistair A Young
Left ventricular (LV) mass and volume are important indicators of clinical and pre-clinical disease processes. However, much of the shape information present in modern imaging examinations is currently ignored. Morphometric atlases enable precise quantification of shape and function, but there has been no objective comparison of different atlases in the same cohort. We compared two independent LV atlases using MRI scans of 4547 UK Biobank participants: (i) a volume atlas derived by automatic non-rigid registration of image volumes to a common template, and (ii) a surface atlas derived from manually drawn epicardial and endocardial surface contours...
February 4, 2019: Scientific Reports
Ted K Yanagihara, J Ricardo McFaline-Figueroa, Nicholas J Giacalone, Albert W Lee, Vikram Soni, Mark E Hwang, Kristin T Hsieh, Anurag Saraf, Cheng-Chia Wu, Daniel Yang, Patrick Y Wen, Hani Ashamalla, Ayal A Aizer, Tony J C Wang, Raymond Y Huang
Background: Whole-brain radiotherapy (WBRT) in patients with brain metastases (BM) is associated with neurocognitive decline. Given its crucial role in learning and memory, efforts to mitigate this toxicity have mostly focused on sparing radiation to the hippocampus. We hypothesized BMs are not evenly distributed across the brain and that several additional areas may be avoided in WBRT based on a low risk of developing a BM. Methods: We contoured 2,757 lesions in a large, single-institution database of patients with newly diagnosed BMs...
January 23, 2019: Neuro-oncology
Ariel H Curiale, Flavio D Colavecchia, German Mato
OBJECTIVE: This paper proposes a novel approach for automatic left ventricle (LV) quantification using convolutional neural networks (CNN). METHODS: The general framework consists of one CNN for detecting the LV, and another for tissue classification. Also, three new deep learning architectures were proposed for LV quantification. These new CNNs introduce the ideas of sparsity and depthwise separable convolution into the U-net architecture, as well as, a residual learning strategy level-to-level...
February 2019: Computer Methods and Programs in Biomedicine
Agata Gawryszuk, Hendrik P Bijl, Monique Holwerda, Gyorgy B Halmos, Jan Wedman, Max J H Witjes, Anton M van der Vliet, Bart Dorgelo, Johannes A Langendijk
BACKGROUND AND PURPOSE: In a separate article (PART 1), a rationale and explanation of the physiology-and-anatomy-based concept of Functional Swallowing Units (FSUs) was presented. FSUs are swallowing muscles not included in the set of commonly defined swallowing organs at risk (SWOARs). They are involved in three crucial swallowing components: hyolaryngeal elevation (HLE), tongue base retraction (TBR) and tongue motion. This paper is a continuation of PART 1 and it provides detailed computed tomography (CT)-based delineation guidelines for FSUs, which presumably are also at risk of radiation-induced dysphagia...
December 11, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Jacqueline Veera, Karen Lim, Jason A Dowling, Chelsie O'Connor, Lois C Holloway, Shalini K Vinod
INTRODUCTION: Magnetic Resonance Imaging (MRI) provides excellent soft tissue definition of pelvic tumours and organs. The aim of this study was to quantify differences in delineated clinical target volumes (CTVs) between computed tomography (CT) and MRI. METHODS: Twenty patients with locally advanced gynaecological malignancies were recruited. Patients underwent dedicated MRI simulation following CT simulation. Four clinicians independently contoured each CT and MRI...
December 3, 2018: Journal of Medical Imaging and Radiation Oncology
Eric D Morris, Ahmed I Ghanem, Milan V Pantelic, Eleanor M Walker, Xiaoxia Han, Carri K Glide-Hurst
PURPOSE: Radiation dose to the heart and cardiac substructures has been linked to cardiotoxicities. As cardiac substructures are poorly visualized on treatment planning computed tomography (CT), we employed the superior soft tissue contrast of magnetic resonance (MR) imaging to optimize a hybrid MR/CT atlas for substructure dose assessment using CT. METHODS: Thirty-one left breast cancer patients underwent a T2-weighted MR and non-contrast simulation CTs. A radiation oncologist delineated 13 substructures (chambers, great vessels, coronary arteries etc...
November 20, 2018: International Journal of Radiation Oncology, Biology, Physics
Meghan W Macomber, Mark Phillips, Ivan Tarapov, Rajesh Jena, Aditya Nori, David Carter, Loic Le Folgoc, Antonio Criminisi, Matthew J Nyflot
Machine learning for image segmentation could provide expedited clinic workflow and better standardization of contour delineation. We evaluated a new model using deep decision forests of image features in order to contour pelvic anatomy on treatment planning CTs. 193 CT scans from one UK and two US institutions for patients undergoing radiotherapy treatment for prostate cancer from 2012-2016 were anonymized. A decision forest autosegmentation model was trained on a random selection of 94 images from Institution 1 and tested on 99 scans from Institution 1, 2, and 3...
November 22, 2018: Physics in Medicine and Biology
Jianxin Xue, Chengbo Han, Andrew Jackson, Chen Hu, Huan Yao, Weili Wang, James Hayman, Weijun Chen, Jianyue Jin, Gregory P Kalemkerian, Martha Matuzsak, Struti Jolly, Feng-Ming Spring Kong
BACKGROUND AND PURPOSE: Higher cardiac dose was associated with worse overall survival in the RTOG0617 study. Pericardial effusion (PCE) is a common cardiac complication of thoracic radiation therapy (RT). We investigated whether doses of radiation to the heart and pericardium are associated with PCE and overall survival in patients treated with thoracic radiation for non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: A total of 94 patients with medically inoperable/unresectable NSCLC treated with definitive RT in prospective studies were reviewed for this secondary analysis...
November 8, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Giulio Francolini, Isacco Desideri, Icro Meattini, Carlotta Becherini, Francesca Terziani, Emanuela Olmetto, Camilla Delli Paoli, Donato Pezzulla, Mauro Loi, Pierluigi Bonomo, Daniela Greto, Silvia Calusi, Marta Casati, Stefania Pallotta, Lorenzo Livi
BACKGROUND AND PURPOSE: In our institute, breast cancer patients undergoing adjuvant treatment are included in a protocol aimed to reduce cardiovascular morbidity (SAFE-2014, NCT2236806), assessing preclinical heart damage with heart speckle-tracking ultrasound. To develop a dose constraint related to subclinical heart damage, a reliable delineation of heart substructures based on a pre-existing guideline was made. PATIENTS AND METHODS: Heart substructures of 16 left-sided breast cancer patients included in the SAFE protocol were delineated by five operators...
January 2019: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Carl DeSelm, T Jonathan Yang, Oren Cahlon, Jamie Tisnado, Atif Khan, Erin Gillespie, Simon Powell, Alice Ho
PURPOSE: The primary goal was to map the anatomic pattern of isolated nodal recurrences (NR) in the supraclavicular (SCV), axillary, and internal mammary nodes (IMNs) in patients with breast cancer treated with curative-intent surgery with or without radiation therapy (RT). Secondary objectives were to assess clinical and pathologic factors associated with patterns of NR and survival rates. METHODS AND MATERIALS: Patients with NR after treatment at a single cancer center during 1998 to 2013 were identified...
March 1, 2019: International Journal of Radiation Oncology, Biology, Physics
Bence Dorogi, Bence Bukovszky, Tamás Mátrai, Ákos Sávolt, Csaba Polgár, Péter Kelemen, Tibor Kovács, Ferenc Rényi-Vámos, Gabriella Ivády, Eszter Kovács, Melinda Téglás, Miklós Kásler, Zoltán Mátrai
INTRODUCTION: The aims of this study were to investigate the correlation between lymphatic drainage and the sentinel lymph node (SLN) status of the subregions in the context of the clinic-pathological parameters of the tumour and the coverage of the axillary volumes by standard and high tangential fields (STgF and HTgF) for whole breast radiotherapy and axillary reverse mapping (ARM). PATIENTS AND METHODS: 933 women with early breast cancer and clinically negative axillary status underwent breast surgery and SLN biopsy followed by axillary lymph node dissection in SLN-positive cases...
October 7, 2018: European Journal of Surgical Oncology
Ali Afzali, Farshid Babapour Mofrad, Majid Pouladian
Detailed knowledge of anatomical lung variation is very important in medical image processing. Normal variations of lung consistent with the maintenance of pulmonary health and abnormal lung variations can be as a result of a pulmonary disease. Inter-patient lung variations can be due to the several factors such as sex, age, height, weight and type of disease. This study tries to show the inter-patient lung variations by using one of the shape-based descriptions techniques which is called Fourier descriptors...
October 13, 2018: Journal of Medical Systems
Yangkun Luo, Yujin Xu, Zhongxing Liao, Daniel Gomez, Jingqian Wang, Wei Jiang, Rongrong Zhou, Ryan Williamson, Laurence E Court, Jinzhong Yang
PURPOSE: We evaluated the feasibility of using an automatic segmentation tool to delineate cardiac substructures from noncontrast computed tomography (CT) images for cardiac dosimetry and toxicity analyses for patients with nonsmall cell lung cancer (NSCLC) after radiotherapy. MATERIAL AND METHODS: We used an in-house developed multi-atlas segmentation tool to delineate 11cardiac substructures, including the whole heart, four heart chambers, and six greater vessels, automatically from the averaged 4D-CT planning images of 49 patients with NSCLC...
October 11, 2018: Acta Oncologica
Kenta Ninomiya, Hidetaka Arimura, Motoki Sasahara, Yudai Kai, Taka-Aki Hirose, Saiji Ohga
This study aimed to investigate the feasibility of anatomical feature points for the estimation of prostate locations in the Bayesian delineation frameworks for prostate cancer radiotherapy. The relationships between the reference centroids of prostate regions (CPRs) (prostate locations) and anatomical feature points were explored, and the most feasible anatomical feature points were selected based on the smallest location estimation errors of CPRs and the largest Dice's similarity coefficient (DSC) between the reference and extracted prostates...
December 2018: Radiological Physics and Technology
Francis Ho, Jeremy Tey, David Chia, Yu Yang Soon, Chek Wee Tan, Sarahatul Bahiah, Timothy Cheo, Ivan Weng Keong Tham
Temporal lobe necrosis as result of radiation for nasopharyngeal cancer (NPC) occurs up to 28% of NPC patients. The only effective mitigation is by strict adherence to temporal lobe dose tolerances during radiotherapy planning, which in turn hinges on accurate temporal lobe delineation. We aim to improve the accuracy and to standardize temporal lobe contouring for patients receiving head and neck radiotherapy for NPC in a tertiary teaching hospital in Singapore.The baseline data were obtained from 10 patients in the diagnostic phase and the effect of interventions were measured in 37 patients who underwent head and neck radiotherapy over a 6-month period...
September 2018: Medicine (Baltimore)
K Armstrong, J Ward, N M Hughes, A Mihai, A Blayney, C Mascott, R Kileen, J Armstrong
AIMS: Postoperative radiotherapy is the standard of care for resected major salivary cancers that are at risk of locoregional recurrence. Of the various histological subtypes, perineural invasion is most common in adenoidcystic carcinomas of the three major salivary glands - parotid, submandibular and sublingual. The clinical target volume (CTV) for these cases must include the relevant cranial nerve pathways at risk. A contouring atlas was devised for delineation of the CTV of the nerves supplying the major salivary glands...
December 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
Hossein Arabi, Jason A Dowling, Ninon Burgos, Xiao Han, Peter B Greer, Nikolaos Koutsouvelis, Habib Zaidi
PURPOSE: Magnetic resonance imaging (MRI)-guided radiation therapy (RT) treatment planning is limited by the fact that the electron density distribution required for dose calculation is not readily provided by MR imaging. We compare a selection of novel synthetic CT generation algorithms recently reported in the literature, including segmentation-based, atlas-based and machine learning techniques, using the same cohort of patients and quantitative evaluation metrics. METHODS: Six MRI-guided synthetic CT generation algorithms were evaluated: one segmentation technique into a single tissue class (water-only), four atlas-based techniques, namely, median value of atlas images (ALMedian), atlas-based local weighted voting (ALWV), bone enhanced atlas-based local weighted voting (ALWV-Bone), iterative atlas-based local weighted voting (ALWV-Iter), and a machine learning technique using deep convolution neural network (DCNN)...
September 14, 2018: Medical Physics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"