Lukas Mesik, Samuel Parkins, Daniel Severin, Bryce D Grier, Gabrielle Ewall, Sumasri Kotha, Christian Wesselborg, Cristian Moreno, Yanis Jaoui, Adrianna Felder, Brian Huang, Marina B Johnson, Timothy P Harrigan, Anna E Knight, Shane W Lani, Théo Lemaire, Alfredo Kirkwood, Grace M Hwang, Hey-Kyoung Lee
Transcranial focused ultrasound stimulation (tFUS) is a noninvasive neuromodulation technique, which can penetrate deeper and modulate neural activity with a greater spatial resolution (on the order of millimeters) than currently available noninvasive brain stimulation methods, such as transcranial magnetic stimulation (TMS) and transcranical direct current stimulation (tDCS). While there are several studies demonstrating the ability of tFUS to modulate neuronal activity, it is unclear whether it can be used for producing long-term plasticity as needed to modify circuit function, especially in adult brain circuits with limited plasticity such as the thalamocortical synapses...
February 5, 2024: Journal of Neuroscience