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Raymond A van Adrichem, Banne Nemeth, Ale Algra, Saskia le Cessie, Frits R Rosendaal, Inger B Schipper, Rob G H H Nelissen, Suzanne C Cannegieter
BACKGROUND: The use of thromboprophylaxis to prevent clinically apparent venous thromboembolism after knee arthroscopy or casting of the lower leg is disputed. We compared the incidence of symptomatic venous thromboembolism after these procedures between patients who received anticoagulant therapy and those who received no anticoagulant therapy. METHODS: We conducted two parallel, pragmatic, multicenter, randomized, controlled, open-label trials with blinded outcome evaluation: the POT-KAST trial, which included patients undergoing knee arthroscopy, and the POT-CAST trial, which included patients treated with casting of the lower leg...
February 9, 2017: New England Journal of Medicine
K Tamreihao, Debananda S Ningthoujam, Salam Nimaichand, Elangbam Shanta Singh, Pascal Reena, Salam Herojeet Singh, Upendra Nongthomba
Streptomyces corchorusii strain UCR3-16, obtained from rice rhizospheric soils showed antifungal activities against 6 major rice fungal pathogens by diffusible and volatile compounds production. The strain was found positive for production of fungal cell wall degrading enzymes such as chitinase, β-1,3-glucanase, β-1,4-glucanase, lipase and protease. The strain was also positive for plant growth promoting traits. It produced up to 30.5μg/ml of IAA and solubilized a significant amount of inorganic phosphate (up to 102μg/ml)...
November 2016: Microbiological Research
Grigory A Shamov, Peter H M Budzelaar, Georg Schreckenbach
Most of the commonly used approximate density functionals have systematic errors in the description of the stability of hydrocarbons. This poses a challenge for the realistic modeling of reactions involving hydrocarbons, such as olefin polymerization. Practical remedies have been proposed, including the application to usual black-box DFT of additional empirical correction CR(-6) terms for the van der Waals interaction (termed DFT-D), or introducing additional pseudopotentials that introduce some medium-to-long-range attraction (C-Pot)...
February 9, 2010: Journal of Chemical Theory and Computation
Marjolein A Veerbeek, Richard C Oude Voshaar, Anne Margriet Pot
ABSTRACT Background: Meta-analyses show efficacy of several psychological and pharmacological interventions for late-life psychiatric disorders, but generalization of effects to routine mental health care for older people remains unknown. Aim of this study is to investigate the improvement of functioning within one year of referral to an outpatient mental health clinic for older adults. Methods: Pre-post measurement of the Health of Nations Outcome Scale 65+ (HoNOS 65+) in 704 older people referred for psychiatric problems (no dementia) to any of the seven participating mental health care organizations...
April 23, 2014: International Psychogeriatrics
Mary Ellen Sanders, Todd R Klaenhammer, Arthur C Ouwehand, Bruno Pot, Eric Johansen, James T Heimbach, Maria L Marco, Julia Tennilä, R Paul Ross, Charles Franz, Nicolas Pagé, R David Pridmore, Greg Leyer, Seppo Salminen, Duane Charbonneau, Emma Call, Irene Lenoir-Wijnkoop
Commercial probiotic strains for food or supplement use can be altered in different ways for a variety of purposes. Production conditions for the strain or final product may be changed to address probiotic yield, functionality, or stability. Final food products may be modified to improve flavor and other sensory properties, provide new product formats, or respond to market opportunities. Such changes can alter the expression of physiological traits owing to the live nature of probiotics. In addition, genetic approaches may be used to improve strain attributes...
February 2014: Annals of the New York Academy of Sciences
A P S Hungin, C Mulligan, B Pot, P Whorwell, L Agréus, P Fracasso, C Lionis, J Mendive, J-M Philippart de Foy, G Rubin, C Winchester, N de Wit
BACKGROUND: Evidence suggests that the gut microbiota play an important role in gastrointestinal problems. AIM: To give clinicians a practical reference guide on the role of specified probiotics in managing particular lower gastrointestinal symptoms/problems by means of a systematic review-based consensus. METHODS: Systematic literature searching identified randomised, placebo-controlled trials in adults; evidence for each symptom/problem was graded and statements developed (consensus process; 10-member panel)...
October 2013: Alimentary Pharmacology & Therapeutics
Marjolein A Veerbeek, Richard C Oude Voshaar, Anne Margriet Pot
BACKGROUND: The Health of the Nation Outcome Scales (HoNOS) is widely used to evaluate mental health care outcomes. For appropriate use and interpretation in routine clinical practice, further validation of the adapted version for older clients (HoNOS 65+) is needed. OBJECTIVE: The aim of this study is to compare scoring profiles produced by different categories of professionals, assess the internal consistency of the sum score and proposed subscales, and concurrent validity of the total sum score of the Dutch version of HoNOS 65+...
December 2013: International Journal of Nursing Studies
Paula M C Mommersteeg, Irene Pot, Wilbert Aarnoudse, Johan Denollet, Jos W Widdershoven
PURPOSE: To examine whether Type D--distressed--personality is independently associated with patient reported health outcomes, such as chest pain, health status and emotional distress, in patients with angiographically nonsignificant coronary abnormalities. Psychosocial factors, such as Type D personality, are risk factors for established coronary artery disease (CAD), but are unknown for patients with non-obstructive CAD. METHODS: A total of 273 patients (62 years, SD 10, 49 % male) participated in the cross-sectional part of the 'TWeesteden mIld STenosis' study...
October 2013: Quality of Life Research
M A Veerbeek, Y J Pijl, G A M Driessen, S C de Vries, A M Pot
TRENDS IN THE UTILIZATION OF DUTCH MENTAL HEALTH SERVICES BY OLDER ADULTS BETWEEN 1990-2004: AimBecause the Dutch population has a growing number of older people, an increasing burden on mental health services is expected. To facilitate policy making for the future, it is important to know what changes there have been in use of mental health services by elderly in the past. This study investigates changes in the use of mental health services by older adults in the period 1990-2004. Methods: Information about the use of mental health services by older adults was retrieved from the Dutch Psychiatric Case Registers...
April 2009: Tijdschrift Voor Gerontologie en Geriatrie
Ruth H Keogh, Jin Young Park, Ian R White, Marleen A H Lentjes, Alison McTaggart, Amit Bhaniani, Benjamin J Cairns, Timothy J Key, Darren C Greenwood, Victoria J Burley, Janet E Cade, Christina C Dahm, Gerda K Pot, Alison M Stephen, Gabriel Masset, Eric J Brunner, Kay-Tee Khaw
The alcohol-breast cancer association has been established using alcohol intake measurements from Food Frequency Questionnaires (FFQ). For some nutrients diet diary measurements are more highly correlated with true intake compared with FFQ measurements, but it is unknown whether this is true for alcohol. A case-control study (656 breast cancer cases, 1905 matched controls) was sampled from four cohorts in the UK Dietary Cohort Consortium. Alcohol intake was measured prospectively using FFQs and 4- or 7-day diet diaries...
July 2012: European Journal of Epidemiology
Francesca Stefani, Giuseppe Nardon, Raffaele Bonato, Anna Modenese, Chiara Novello, Renata Ferrari
UNLABELLED: Pain in intensive care units is a frequent and often undermanaged problem, mainly because appropriate pain assessment tools for non communicative patients are still missing. The Critical-Care Pain Observation Tool (C-POT) is currently considered one of the best scales, both for psychometric properties and clinical feasibility. AIM: To preliminarily analyze the reliability and validity of the C-POT in a hospital setting, and its clinical feasibility. METHODS: 50 nursing staff members from three different critical care settings of Vicenza Hospital administered the C-POT to 121 in patients, at rest and after usual nursing care activities...
July 2011: Assistenza Infermieristica e Ricerca: AIR
Héctor Miguel Conesa, Rainer Schulin, Bernd Nowack
BACKGROUND, AIM, AND SCOPE: Diffusive gradients in thin films (DGT) have been recognized as a suitable tool to assess in situ metal bioavailability in soils. Mine tailings have some singular characteristics such as high heavy-metal concentrations, low pH, or absence of water retention capacity that may compromise the correct application of this technique whose applicability is known to be pH dependent. The goal of this study was to determine the response of DGT devices in heavy-metal-polluted mine tailings with different pH...
March 2010: Environmental Science and Pollution Research International
M A Veerbeek, Y J Pijl, G A M Driessen, S C de Vries, A M Pot
AIM: Because the Dutch population has a growing number of older people, an increasing burden on mental health services is expected. To facilitate policy making for the future, it is important to know what changes there have been in use of mental health services by elderly in the past. This study investigates changes in the use of mental health services by older adults in the period 1990-2004. METHODS: Information about the use of mental health services by older adults was retrieved from the Dutch Psychiatric Case Registers...
April 2009: Tijdschrift Voor Gerontologie en Geriatrie
Vishal M Gohil, Miriam L Greenberg
Mitochondrial membrane biogenesis requires the import and synthesis of proteins as well as phospholipids. How the mitochondrion regulates phospholipid levels and maintains a tight protein-to-phospholipid ratio is not well understood. Two recent papers (Kutik, S., M. Rissler, X.L. Guan, B. Guiard, G. Shui, N. Gebert, P.N. Heacock, P. Rehling, W. Dowhan, M.R. Wenk, et al. 2008. J. Cell Biol. 183:1213-1221; Osman, C., M. Haag, C. Potting, J. Rodenfels, P.V. Dip, F.T. Wieland, B. Brügger, B. Westermann, and T...
February 23, 2009: Journal of Cell Biology
P Mattarelli, C Bonaparte, B Pot, B Biavati
In the year 2002, Bifidobacterium longum, Bifidobacterium infantis and Bifidobacterium suis were unified into a single species, Bifidobacterium longum, preserving the former species names through the creation of the three biotypes 'longum', 'infantis' and 'suis'. Consequently, the use of the species names B. infantis and B. suis was to be discontinued. The above taxonomic rearrangement of B. longum was based on DNA-DNA hybridizations and 16S rRNA and HSP60 gene sequence analysis. However, a variety of other genotypic techniques including ribotyping, amplified rDNA restriction analysis (ARDRA), randomly amplified polymorphic DNA (RAPD)-PCR, BOX-PCR, PCR-denaturing gradient gel electrophoresis (DGGE), comparison of the recA, tuf and ldh gene sequences, plasmid profiling and considerable variation in carbohydrate fermentation patterns as well as results of starch and PAGE electrophoresis experiments clearly discriminate former B...
April 2008: International Journal of Systematic and Evolutionary Microbiology
Jeremy D Glasner, Guy Plunkett, Bradley D Anderson, David J Baumler, Bryan S Biehl, Valerie Burland, Eric L Cabot, Aaron E Darling, Bob Mau, Eric C Neeno-Eckwall, David Pot, Yu Qiu, Anna I Rissman, Sara Worzella, Sam Zaremba, Joel Fedorko, Tom Hampton, Paul Liss, Michael Rusch, Matthew Shaker, Lorie Shaull, Panna Shetty, Silpa Thotakura, Jon Whitmore, Frederick R Blattner, John M Greene, Nicole T Perna
ERIC, the Enteropathogen Resource Integration Center (, is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefense-diarrheagenic Escherichia coli, Shigella spp., Salmonella spp., Yersinia enterocolitica and Yersinia pestis. More than 30 genomes have been completely sequenced, many more exist in draft form and additional projects are underway. These organisms are increasingly the focus of studies using high-throughput experimental technologies and computational approaches...
January 2008: Nucleic Acids Research
W P Achterberg, C van Campen, A M Pot, A Kerkstra, M W Ribbe
The objective of the paper is to review the effects of the implementation of the Resident Assessment Instrument (RAI) on process measures (quality of care plans and staff satisfaction) and outcome measures (health problems and quality of life) in nursing homes. All available publications on the effects of the RAI were included in the review. The most positive effects of the RAI were found in improvements in the comprehensiveness and accuracy of the care plans. As regards outcome quality, the RAI method had most positive effects on the health condition of nursing home residents with diminished physical and mental functioning...
September 1999: Scandinavian Journal of Rehabilitation Medicine
H C Comijs, A M Pot, J H Smit, L M Bouter, C Jonker
OBJECTIVES: (1) To assess the prevalence and the consequences of chronic verbal aggression, physical aggression, financial mistreatment, and neglect in a community-based sample; (2) to investigate the circumstances that led to the abuse and the ways in which the victims handled the problem. DESIGN: Prevalence was assessed in a population-based sample of 1797 older people living independently in Amsterdam, the Netherlands. In a follow-up study 1 year later, the victims were questioned again about the background and consequences of the abuse...
July 1998: Journal of the American Geriatrics Society
M C MacNicol, D Pot, A M MacNicol
We describe a plasmid, pXen, designed for the optimized expression of proteins fused to glutathione-S-transferase (GST) in Xenopus laevis oocytes and embryos. The Xenopus model system permits the biochemical analysis of signaling pathways and analysis of embryo phenotype in response to manipulation of proto-oncogene expression. pXen is a modified pSP64T vector which contains an SP6 RNA polymerase promoter followed by the translational initiation sequence of Xenopus beta-globin and the glutathione binding domain of GST...
September 1, 1997: Gene
P Descheemaeker, C Lammens, B Pot, P Vandamme, H Goossens
The increasing problems encountered with enterococcal nosocomial infections and the intrinsic and acquired resistance of the enterococci to different antimicrobial compounds highlight the need for a rapid identification technique. Enterococcus faecalis is readily identified by biochemical tests, but species differentiation within the Enterococcus faecium and Enterococcus gallinarum species groups is less well established. In the present study, 66 strains representing the most prevalent human enterococci were used to develop a PCR-based species-specific identification protocol...
April 1997: International Journal of Systematic Bacteriology
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