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Keywords Aortic regurgitation quantific...

Aortic regurgitation quantification

https://read.qxmd.com/read/38517604/assessing-regurgitation-severity-adverse-remodeling-and-fibrosis-with-cmr-in-aortic-regurgitation
#1
REVIEW
Mujtaba Saeed, Akila Bersali, Amr Darwish, Fatima Qamar, Dimitrios Maragiannis, Kinan Carlos El-Tallawi, Maan Malahfji, Dipan J Shah
PURPOSE OF REVIEW: Cardiac magnetic resonance (CMR) is emerging as a valuable imaging modality for the assessment of aortic regurgitation (AR). In this review, we discuss the assessment of AR severity, left ventricular (LV) remodeling, and tissue characterization by CMR while highlighting the latest studies and addressing future research needs. RECENT FINDINGS: Recent studies have further established CMR-based thresholds of AR severity and LV remodeling that are associated with adverse clinical outcomes, and lower than current guideline criteria...
March 22, 2024: Current Cardiology Reports
https://read.qxmd.com/read/38347221/fibrosis-and-expression-of-extracellular-matrix-proteins-in-human-interventricular-septum-in-aortic-valve-stenosis-and-regurgitation
#2
JOURNAL ARTICLE
David Sedmera, Alena Kvasilova, Adam Eckhardt, Petr Kacer, Martin Penicka, Matej Kocka, Dana Schindler, Ron Kaban, Radka Kockova
Valvular heart disease leads to ventricular pressure and/or volume overload. Pressure overload leads to fibrosis, which might regress with its resolution, but the limits and details of this reverse remodeling are not known. To gain more insight into the extent and nature of cardiac fibrosis in valve disease, we analyzed needle biopsies taken from the interventricular septum of patients undergoing surgery for valve replacement focusing on the expression and distribution of major extracellular matrix protein involved in this process...
February 12, 2024: Histochemistry and Cell Biology
https://read.qxmd.com/read/38306632/assessment-of-paravalvular-regurgitation-after-transcatheter-aortic-valve-replacement-using-2d-multi-venc-and-4d-flow-cmr
#3
JOURNAL ARTICLE
Maxim J P Rooijakkers, Saloua El Messaoudi, Niels A Stens, Marleen H van Wely, Jesse Habets, Monique Brink, Laura Rodwell, Daniel Giese, Rob J van der Geest, Niels van Royen, Robin Nijveldt
AIMS: To compare the novel 2D multi-venc and 4D flow acquisitions with the standard 2D flow acquisition for the assessment of paravalvular regurgitation (PVR) after TAVR using cardiac magnetic resonance (CMR)-derived regurgitant fraction (RF). METHODS AND RESULTS: In this prospective study, patients underwent CMR one month after TAVR to assess PVR using 2D multi-venc and 4D flow, in addition to standard 2D flow. Scatterplots and Bland-Altman plots were used to assess correlation and visualize agreement between techniques...
February 2, 2024: European Heart Journal Cardiovascular Imaging
https://read.qxmd.com/read/38286950/novel-contouring-method-for-optimizing-mri-flow-quantification-in-patients-with-aortic-valve-disease
#4
JOURNAL ARTICLE
Malek M Yaman, Michael Chetrit, Jennifer Bullen, Michael A Bolen, Scott D Flamm, Deborah Kwon
Optimizing MRI aortic flow quantification is crucial for accurate assessment of valvular disease severity. In this study, we sought to evaluate the accuracy of a novel method of contouring systolic aortic forward flow in comparison to standard contouring methods at various aortic levels. The study included a cohort of patients with native aortic valve (AoV) disease and a small control group referred to cardiac MRI over a 1-year period. Inclusion criteria included aortic flow quantification at aortic valve and one additional level, and no or trace mitral regurgitation (MR) documented both by the MRI AND an echocardiogram done within a year...
January 30, 2024: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/37892913/blood-speckle-imaging-an-emerging-method-for-perioperative-evaluation-of-subaortic-and-aortic-valvar-repair
#5
JOURNAL ARTICLE
Elias Sundström, Michael Jiang, Hani K Najm, Justin T Tretter
BACKGROUND: This article presents the use of blood speckle Imaging (BSI) as an echocardiographic approach for the pre- and post-operative evaluation of subaortic membrane resection and aortic valve repair. METHOD: BSI, employing block-matching algorithms, provided detailed visualization of flow patterns and quantification of parameters from ultrasound data. The 9-year-old patient underwent subaortic membrane resection and peeling extensions of the membrane from under the ventricular-facing surface of all three aortic valve leaflets...
October 12, 2023: Bioengineering
https://read.qxmd.com/read/37594503/computed-tomography-to-guide-transcatheter-aortic-valve-implantation
#6
REVIEW
Marwa Daghem, Florian Weidinger, Stephan Achenbach
Since its introduction in 2022, transcatheter aortic valve implantation (TAVI) has revolutionized the treatment and prognosis of patients with aortic stenosis. Robust clinical trial data and a wealth of scientific evidence support its efficacy and safety. One of the key factors for success of the TAVI procedure is careful preprocedural planning using imaging. Computed tomography (CT) has developed into the standard imaging method for comprehensive patient assessment in this context. Suitability of the femoral and iliac arteries for transfemoral access, exact measurement of aortic annulus size and geometry as the basis for prosthesis selection, quantification of the spatial relationship of the coronary ostia to the aortic annular plane, and identification of optimal fluoroscopic projection angles for the implantation procedure are among the most important information that can be gained from preprocedural CT...
August 18, 2023: Herz
https://read.qxmd.com/read/37496072/cardiac-reverse-remodeling-in-primary-mitral-regurgitation-mitral-valve-replacement-vs-mitral-valve-repair
#7
MULTICENTER STUDY
Thomas P Craven, Pei G Chew, Laura E Dobson, Miroslawa Gorecka, Martine Parent, Louise A E Brown, Christopher E D Saunderson, Arka Das, Amrit Chowdhary, Nicholas Jex, David M Higgins, Erica Dall'Armellina, Eylem Levelt, Dominik Schlosshan, Peter P Swoboda, Sven Plein, John P Greenwood
BACKGROUND: When feasible, guidelines recommend mitral valve repair (MVr) over mitral valve replacement (MVR) to treat primary mitral regurgitation (MR), based upon historic outcome studies and transthoracic echocardiography (TTE) reverse remodeling studies. Cardiovascular magnetic resonance (CMR) offers reference standard biventricular assessment with superior MR quantification compared to TTE. Using serial CMR in primary MR patients, we aimed to investigate cardiac reverse remodeling and residual MR post-MVr vs MVR with chordal preservation...
July 27, 2023: Journal of Cardiovascular Magnetic Resonance
https://read.qxmd.com/read/37478870/non-contact-quantification-of-aortic-stenosis-and-mitral-regurgitation-using-carotid-waveforms-from-skin-displacements
#8
JOURNAL ARTICLE
Prashanna Khwaounjoo, Alex Dixon, Amir Hajirassouliha, Emily Lam Po Tang, Mark Webster, Andrew Taberner, Poul M F Nielsen, Martyn P Nash, Yusuf Cakmak
Early diagnosis of heart problems is essential for improving patient prognosis. We created a non-contact imaging system that calculates the vessel-induced deformation of the skin to estimate the carotid artery pressure displacement waveforms. We present a clinical study of the system in patients (n = 27) with no underlying condition, aortic stenosis (AS), or mitral regurgitation (MR). Displacement waveforms were compared to aortic catheter pressures in the same patients. The morphologies of the pressure and displacement waveforms were found to be similar, and pulse wave analysis metrics, such as our modified reflection indices (RI) and waveform duration proportions, showed no significant differences...
July 21, 2023: Physiological Measurement
https://read.qxmd.com/read/37322317/mitral-valve-regurgitation-assessed-by-intraventricular-cmr-4d-flow-a-systematic-review-on-the-technological-aspects-and-potential-clinical-applications
#9
REVIEW
Yasaman Safarkhanlo, Bernd Jung, Benedikt Bernhard, Eva S Peper, Raymond Y Kwong, Jessica A M Bastiaansen, Christoph Gräni
Cardiac magnetic resonance (CMR) four-dimensional (4D) flow is a novel method for flow quantification potentially helpful in management of mitral valve regurgitation (MVR). In this systematic review, we aimed to depict the clinical role of intraventricular 4D-flow in MVR. The reproducibility, technical aspects, and comparison against conventional techniques were evaluated. Published studies on SCOPUS, MEDLINE, and EMBASE were included using search terms on 4D-flow CMR in MVR. Out of 420 screened articles, 18 studies fulfilled our inclusion criteria...
June 16, 2023: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/37213875/role-of-multimodality-imaging-in-transcatheter-structural-interventions
#10
JOURNAL ARTICLE
Amr Telmesani, Su Min Chang, Nadeen Faza, Stephen H Little, Dipan J Shah
Cardiac imaging is the backbone for safe and optimal transcatheter structural interventions. Transthoracic echocardiogram is the initial modality to assess valvular disorders, while transesophageal echocardiogram is best to delineate the mechanism of valvular regurgitation, preprocedural assessment for transcatheter edge-to-edge repair, and for intraprocedural guidance. Cardiac computed tomography is the modality of choice for assessing calcifications, maneuvering multiplaner reconstruction of different cardiac structures, preprocedural planning for various transcatheter valve replacement, and assessing for hypoattenuated leaflet thickening and reduced leaflet motion...
2023: Methodist DeBakey Cardiovascular Journal
https://read.qxmd.com/read/37183830/ultra-low-radiation-dose-and-contrast-volume-ct-protocol-and-tavi-ct-score-for-tavi-planning-and-outcome
#11
JOURNAL ARTICLE
Marco Fogante, Paolo Esposto Pirani, Fatjon Cela, Liliana Balardi, Tommaso Piva, Giulio Argalia, Nicolò Schicchi
OBJECTIVE: To investigate the feasibility of an ultra-low radiation dose and contrast volume protocol using third-generation dual-source (DS) CT for transcatheter aortic valve implantation (TAVI) planning with coronary artery disease (CAD) assessment, coronary artery calcium score (CACS) and aortic valve calcium score (AVCS) quantification and to evaluate their relationship with TAVI outcome. METHODS: In this retrospective study were selected 203 patients (131 males, 79...
May 15, 2023: British Journal of Radiology
https://read.qxmd.com/read/37028710/angiographic-quantification-of-aortic-regurgitation-following-myval-octacor-implantation-independent-core-lab-adjudication
#12
JOURNAL ARTICLE
Ahmed Elkoumy, John Jose, Sengottuvelu Gunasekaran, Asish Kumar, B C Srinivas, C N Manjunath, K S Ravindranath, Maulik Parekh, Praveen Chandra, Rajneesh Kapoor, Mahmoud Abdelshafy, Ashok Seth, Praveer Agrawal, Atul Mathur, Ravindra Singh Rao, Hesham Elzomor, K S Sadanada, Vijay Kumar, Shahram Arsang-Jang, Sanjay Mehrotra, Bagirath Raghuraman, Uday Khanolkar, Rajendra Kumar Premchand, Manik Chopra, Prem Krishna, Haresh Mehta, Rahul Gupta, Viveka Kumar, Nagendra Boopathy, Andreas Baumbach, Patrick W Serruys, Osama Soliman
BACKGROUND: The balloon expandable Myval transcatheter heart valve (THV) showed encouraging results regarding residual aortic regurgitation (AR) from multiple observational studies. The newly designed Myval Octacor has been introduced recently, aiming for a reduction in AR and improved performance. OBJECTIVES: The focus of this study is to report the incidence of AR using the validated quantitative Videodensitometry angiography technology (qLVOT-AR%) in the first in human use of the Myval Octacor THV system...
April 5, 2023: International Journal of Cardiology
https://read.qxmd.com/read/36937904/the-evolving-role-of-cardiovascular-magnetic-resonance-in-the-assessment-of-mitral-valve-prolapse
#13
REVIEW
Emmanuelle Vermes, Alexandre Altes, Laura Iacuzio, Franck Levy, Yohann Bohbot, Cédric Renard, Francesco Grigioni, Sylvestre Maréchaux, Christophe Tribouilloy
Mitral valve prolapse (MVP), characterized by a displacement > 2 mm above the mitral annulus of one or both bileaflets, with or without leaflet thickening, is a common valvular heart disease, with a prevalence of approximately 2% in western countries. Although this population has a generally good overall prognosis, MVP can be associated with mitral regurgitation (MR), left ventricular (LV) remodeling leading to heart failure, ventricular arrhythmia, and, the most devastating complication, sudden cardiac death, especially in myxomatous bileaflet prolapse (Barlow's disease)...
2023: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/36860834/effects-of-mitral-valve-prolapse-on-quantification-of-mitral-regurgitation-and-ejection-fraction-using-cardiac-mri
#14
JOURNAL ARTICLE
Bamidele T Otemuyiwa, Elizabeth M Lee, Edith Sella, Chaitanya Madamanchi, Sowmya Balasubramanian, Tianwen Ma, Aparna Joshi, Jimmy C Lu, Adam L Dorfman, Prachi Agarwal
PURPOSE: To determine the impact of prolapsed volume on regurgitant volume (RegV), regurgitant fraction (RF), and left ventricular ejection fraction (LVEF) in patients with mitral valve prolapse (MVP) using cardiac MRI. MATERIALS AND METHODS: Patients with MVP and mitral regurgitation who underwent cardiac MRI from 2005 to 2020 were identified retrospectively from the electronic record. RegV is the difference between left ventricular stroke volume (LVSV) and aortic flow...
February 2023: Radiology. Cardiothoracic imaging
https://read.qxmd.com/read/36550245/assessment-of-valve-implantation-in-the-descending-aorta-as-an-alternative-for-aortic-regurgitation-patients-not-treatable-with-conventional-procedures
#15
JOURNAL ARTICLE
A García-Galindo, R Agujetas, J R López-Mínguez, C Ferrera
BACKGROUND: Aortic Regurgitation (AR) produces the entrance of an abnormal amount of blood in the left ventricle. This disease is responsible for high morbidity and mortality worldwide and may be caused by an aortic valve dysfunction. Surgical and transcatheter aortic valve replacement (TAVR) are the current options for treating AR. They have replaced older procedures such as Hufnagel's one. However, some physicians have reconsidered this procedure as a less aggressive alternative for patients not eligible for surgical or TAVR...
December 23, 2022: Biomechanics and Modeling in Mechanobiology
https://read.qxmd.com/read/36479573/mitral-annular-calcification-in-patients-with-significant-mitral-valve-disease-an-old-problem-with-new-solutions
#16
REVIEW
Guido Ascione, Paolo Denti
Mitral annular calcification (MAC) is a chronic process involving mitral valve annulus, linked with an increased cardiovascular mortality and morbidity. Since its first autoptic description, a progressive evolution in diagnostic tools brought cardiac computed tomography (CT) scan to become the gold standard in MAC detection and classification. The treatment of significant mitral valve disease in patients with annular calcifications has always represented an issue for cardiac surgeons, being it linked with an increased risk of atrioventricular groove rupture, circumflex artery injury, or embolism...
2022: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/36315529/quantifying-valve-regurgitation-using-3-d-doppler-ultrasound-images-and-deep-learning
#17
JOURNAL ARTICLE
Sigurd Vangen Wifstad, Lasse Lovstakken, Jorgen Avdal, Erik Andreas Rye Berg, Hans Torp, Bjornar Grenne, Stefano Fiorentini
Accurate quantification of cardiac valve regurgitation jets is fundamental for guiding treatment. Cardiac ultrasound is the preferred diagnostic tool, but current methods for measuring the regurgitant volume are limited by low accuracy and high interobserver variability. Following recent research, quantitative estimators of orifice size and regurgitant volume based on high frame rate 3-D ultrasound have been proposed, but measurement accuracy limited by the wide point spread function relative to the orifice size...
October 31, 2022: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://read.qxmd.com/read/36202452/in-the-eye-of-the-beholder-defining-severe-aortic-regurgitation-and-the-timing-of-intervention
#18
EDITORIAL
Sheldon E Litwin
No abstract text is available yet for this article.
October 2022: JACC. Cardiovascular Imaging
https://read.qxmd.com/read/36167535/quantitative-evaluation-of-aortic-valve-regurgitation-in-4d-flow-cardiac-magnetic-resonance-at-which-level-should-we-measure
#19
JOURNAL ARTICLE
Malgorzata Polacin, Julia Geiger, Barbara Burkhardt, Fraser M Callaghan, Emanuela Valsangiacomo, Christian Kellenberger
PURPOSE: To find the best level to measure aortic flow for quantification of aortic regurgitation (AR) in 4D flow CMR. METHODS: In 27 congenital heart disease patients with AR (67% male, 31 ± 16 years) two blinded observers measured antegrade, retrograde, net aortic flow volumes and regurgitant fractions at 6 levels in 4D flow: (1) below the aortic valve (AV), (2) at the AV, (3) at the aortic sinus, (4) at the sinotubular junction, (5) at the level of the pulmonary arteries (PA) and (6) below the brachiocephalic trunk...
September 27, 2022: BMC Medical Imaging
https://read.qxmd.com/read/36093173/intra-cardiac-pressure-drop-and-flow-distribution-of-bicuspid-aortic-valve-disease-in-preserved-ejection-fraction
#20
JOURNAL ARTICLE
Shirin Aliabadi, Alireza Sojoudi, Murad F Bandali, Michael S Bristow, Carmen Lydell, Paul W M Fedak, James A White, Julio Garcia
BACKGROUND: Bicuspid aortic valve (BAV) is more than a congenital defect since it is accompanied by several secondary complications that intensify induced impairments. Hence, BAV patients need lifelong evaluations to prevent severe clinical sequelae. We applied 4D-flow magnetic resonance imaging (MRI) for in detail visualization and quantification of in vivo blood flow to verify the reliability of the left ventricular (LV) flow components and pressure drops in the silent BAV subjects with mild regurgitation and preserved ejection fraction (pEF)...
2022: Frontiers in Cardiovascular Medicine
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