Kyra van der Pan, Sandra de Bruin-Versteeg, Daniela Damasceno, Alejandro Hernández-Delgado, Alita J van der Sluijs-Gelling, Wouter B L van den Bossche, Inge F de Laat, Paula Díez, Brigitta A E Naber, Annieck M Diks, Magdalena A Berkowska, Bas de Mooij, Rick J Groenland, Fenna J de Bie, Indu Khatri, Sara Kassem, Anniek L de Jager, Alesha Louis, Julia Almeida, Jacqueline A M van Gaans-van den Brink, Alex-Mikael Barkoff, Qiushui He, Gerben Ferwerda, Pauline Versteegen, Guy A M Berbers, Alberto Orfao, Jacques J M van Dongen, Cristina Teodosio
Innate myeloid cell (IMC) populations form an essential part of innate immunity. Flow cytometric (FCM) monitoring of IMCs in peripheral blood (PB) has great clinical potential for disease monitoring due to their role in maintenance of tissue homeostasis and ability to sense micro-environmental changes, such as inflammatory processes and tissue damage. However, the lack of standardized and validated approaches has hampered broad clinical implementation. For accurate identification and separation of IMC populations, 62 antibodies against 44 different proteins were evaluated...
2022: Frontiers in Immunology