Jun-Zhe Yi, Zhi-Jian Zhu, Gong-Wei Liu, Yi-Min Zhang, Jie Xu, Xin-Tong Wu, Ke Ding, Jian-Chao Liu, Ke-Fei Zhang, Xiong-Ying Jiang, Qi-Feng Chen, Yue Hu, Song Chen, Sui-Xing Zhong, Jiong-Liang Wang, Ning Lyu, Ming Zhao
AIM: The study was conducted to evaluate the feasibility and safety profile of hepatic arterial infusion chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin (HAIC-FOLFOX) as an alternative therapeutic choice for patients with advanced hepatocellular carcinoma (HCC) that is refractory to systemic treatment including immune checkpoint blockades or molecular targeting agents. METHODS: 245 consecutive patients with advanced HCC who received HAIC-FOLFOX treatment after systemic treatment failure were retrospectively reviewed in six institutions and their survival, tumor response, and tolerance were assessed...
December 28, 2023: Hepatology Research: the Official Journal of the Japan Society of Hepatology