Rubina Kousar, Muhammad Naeem, Mohamad Ikhwan Jamaludin, Ammara Arshad, Aisyah Nazirah Shamsuri, Nelofar Ansari, Samreen Akhtar, Abu Hazafa, Jalal Uddin, Ajmal Khan, Ahmed Al-Harrasi
Cancer is the second leading cause of death all around the world. The natural compounds derived from the endophytic flora of fungi are possible solutions to cancer treatment because they are safe for health, cost-effective, biocompatible and have fewer toxicity issues. The active ingredients in endophytic fungi that are responsible for anti-cancer activities are alkaloids, terpenoids, glycosides, saponin, peptides, steroids, phenols, quinones, and flavonoids. This review highlights the anti-cancer activities of entophytic fungus against human papillary thyroid carcinoma (IHH4), human pancreatic (PANC-1), ovarian (OVCAR-3), hepatic (HepG2), lung (A-549), human lymphoma (U937), human skin carcinoma (A431), breast (MCF-7), and Kaposi's sarcoma...
2022: American Journal of Cancer Research