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Thyroid Medicinal Plants

Yuhang Chen, Xuerong Zhang, Qiaosheng Guo, Liping Cao, Qin Qin, Chen Li, Miao Zhao, Wenming Wang
BACKGROUND: Prunella vulgaris L. has been an important medicinal plant for the treatment of thyroid gland malfunction and mastitis in China for over 2000 years. There is an urgent need to select effective wavelengths for greenhouse cultivation of P. vulgaris as light is a very important factor in P. vulgaris growth. Here, we described the effects of natural light (control) and UV solar exclusion on the morphological and physiological traits, secondary metabolites contents and antioxidant activities of P...
April 1, 2019: Biological Research
Alexa Croitoru, Denisa Ficai, Luminiţa Craciun, Anton Ficai, Ecaterina Andronescu
In the last few years, a great importance has been given to natural materials (such as walnuts, peanuts, chestnuts) due to their medicinal and pharmaceutical uses induced by the presence of natural agents, including polyphenols. Juglans regia is a traditional plant that has been used since ancient times in traditional medicine for the treatment of various diseases like microbial infections, stomach ache, thyroid dysfunctions, cancer, heart diseases and sinusitis. Recently, scientific attention for phytochemical profile of walnut by-products is increasing due to their valuable active constituents...
March 29, 2019: Current Pharmaceutical Design
Wael M Al-Amoudi
Lambda-cyhalothrin (LCT) is a synthetic pyrethroid that is widely used to control insecticide. Ginger is a traditional plant that is widely used as a spice or folk medicine. This study evaluates the antioxidant effect of ginger extract on thyroid toxicity induced by LCT in albino rats. Adult Rats were divided into 4 experimental groups: Group 1: control, Group 2: oral ginger treatment (24 mg/ml, 3 days/week for 4 weeks), Group 3: oral LCT treatment (1/100 LD50 , 3 days/week for 4 weeks), Group 4: oral LCT and ginger mixture treatment...
2018: Toxicology Reports
Dimitry Bazyka, Anatoly Prysyazhnyuk, Natalya Gudzenko, Iryna Dyagil, David Belyi, Vadim Chumak, Volodymyr Buzunov
This article summarizes the results of 30 y of follow-up of cancer and noncancer effects in Ukrainian cleanup workers after the Chornobyl accident. The number of power plant employees and first responders with acute radiation syndrome under follow-up by the National Research Center for Radiation Medicine decreased from 179 in 1986-1991 to 105 in 2011-2015. Cancers and leukemia (19) and cardiovascular diseases (21) were the main causes of deaths among acute radiation syndrome survivors (54) during the postaccident period...
July 2018: Health Physics
Mahdieh Abbasalizad Farhangi, Parvin Dehghan, Siroos Tajmiri
BACKGROUND: Hashimoto's thyroiditis is associated with serious alterations in serum lipids and glucose homeostasis. The aims of the current study were to evaluate the effect of powdered Nigella sativa on serum lipids, glucose homeostasis and anthropometric variables in patients with Hashimoto's thyroiditis. METHODS: Forty patients with Hashimoto's thyroiditis, aged between 22 and 50 years old, participated in the trial and were randomly allocated into two groups of intervention and control receiving powdered Nigella sativa or placebo daily for 8 weeks...
March 27, 2018: Lipids in Health and Disease
Sahar Dehdari, Homa Hajimehdipoor
Background: Adiantum capillus-veneris Linn (Maidenhair fern) is an herb belonging to the family Pteridaceae. It is named as " Pare-siavashan " in medical and pharmaceutical textbooks of Iranian Traditional Medicine. The fronds of Maidenhair fern were mainly administrated by ancient physicians as single medicine or in combination with other plants in multi-herbal formulations for curing different diseases. Because of different chemical compositions, the herb fronds were also assessed for its numerous pharmacological effects...
February 2018: Iranian Journal of Public Health
Luã Tainã Costa Reis, Magnus Régios Dias da Silva, Silvia Lima Costa, Eudes da Silva Velozo, Ronan Batista, Suzana Telles da Cunha Lima
Background: A number of medicinal plants are traditionally used for metabolic disorders in Bahia state, Brazil. The aim of this study was to evaluate the estrogen receptor (ER) and thyroid receptor (TR) activation of crude extracts prepared from 20 plants. Methods: Species were extracted and assayed for receptor activation through both ER and TR gene-reporter assays, using 17β-estradiol and triiodothyronine (T3), respectively, as the positive controls. Results: Cajanus cajan (Fabaceae), Abarema cochliacarpus (Fabaceae), and Borreria verticillata (Rubiaceae) were able to activate ER as much as the positive control (17β-estradiol)...
January 15, 2018: Medicines (Basel, Switzerland)
I S Karpova
AIM: Growing interest in lectins is based on their diagnostic and pharmacological potential, especially the ability to inhibit proliferation and initiate apoptosis of cancer cells. In our research microplate lectinoassay able to detect carbohydrate containing structures (receptors) on erythrocyte surface have been proposed for Chornobyl cleanup workers (1986) monitoring. It was expected to reveal specific abnormalities associated with pathological condition arising as a result of late radiation effects...
December 2016: Experimental Oncology
Mahdieh Abbasalizad Farhangi, Parvin Dehghan, Siroos Tajmiri, Mehran Mesgari Abbasi
BACKGROUND: Hashimoto's thyroiditis is an autoimmune disorder and the most common cause of hypothyroidism. The use of Nigella sativa, a potent herbal medicine, continues to increase worldwide as an alternative treatment of several chronic diseases including hyperlipidemia, hypertension and type 2 diabetes mellitus (T2DM). The aim of the current study was to evaluate the effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) - 1, Nesfatin-1 and anthropometric features in patients with Hashimoto's thyroiditis...
November 16, 2016: BMC Complementary and Alternative Medicine
Nisha Panth, Keshav Raj Paudel, Rajendra Karki
Juglans regia Linn. (Juglandaceae), popularly known as English or Persian walnut, is a valuable medicinal plant with a potency to cure various diseases in traditional medicine. Since ancient time, different local ethnic groups have used various part of J. regia for a wide array of ailments including helminthiasis, diarrhea, sinusitis, stomach ache, arthritis, asthma, eczema, scrofula, skin disorders, diabetes mellitus, anorexia, thyroid dysfunction, cancer and infectious diseases. Biological activities of J...
September 2016: Journal of Integrative Medicine
Xiaojing Jin, Shujun Wang, Xuemin Zhao, Qian Jin, Chenling Fan, Jing Li, Zhongyan Shan, Weiping Teng
Coumestrol is a common phytoestrogen found in plants and Chinese medicinal herbs. Its influences on experimental autoimmune thyroiditis (EAT) were investigated in this study. Female adult CBA/J mice were fed with drinking water containing 1% Tween80 only (Control group), 0.8 mg/l (L group) and 8 mg/l coumestrol (H group) from 6 to 15 weeks of age, respectively. Their serum coumestrol concentrations were determined by high performance liquid chromatography, which were undetectable, 43.70 ± 21.74 ng/ml and 135...
August 16, 2016: Oncotarget
Hiroki Shimura
In order to promote further advances of medical systems in the Tohoku region where the Great East Japan Earthquake and the subsequent accident at the Fukushima Dai-ichi Nuclear Power Plant occurred, the requirement of human resources in clinical laboratory medicine has increased. Therefore, the symposium entitled "Human resource development for Tohoku region after Great East Japan Earthquake" was held in The 47th Tohoku Regional Congress of Japanese Society of Laboratory Medicine. In Fukushima Prefecture, the Thyroid Ultrasound Examination program has been conducted since Oct...
January 2016: Rinsho Byori. the Japanese Journal of Clinical Pathology
Luka Kristanc, Samo Kreft
A tremendous surge of public interest in natural therapies has been reported in the past several decades in both developing and developed countries. Furthermore, edible wild-growing plants whose use had long been associated with poverty and famine have also gained in popularity among people in developed countries. An important fraction of herbal products evade all control measures and are generally perceived as safe. However, this may not always be true. It is important to recognize that some plants are not associated with acute toxicity but rather produce more insidious problems, which develop only with long-term exposure...
June 2016: Food and Chemical Toxicology
Shan Xu, Fan Zhang, Peng-peng Liu, Tian-zhu Jia
OBJECTIVE: To compare the pharmacodynamic indicators of Phellodendri Chinensis Cortex with its processed products, in order to study the processing mechanism. METHODS: The effects of raw Phellodendri Chinensis Cortex and its processed products on 17 kinds of indicators in rats were compared, such as the biological characteristics (weight and rectal temperature), material metabolism (lactic acid, acetone acid and triglyceride), energy metabolism (Na+ - K+ -ATPase, Ca2+ -Mg2+ -ATPase, LDH, SDH and liver glyco- gen), thyroid function axis (T3, T4, TSH and TRH), cyclic nucleotide ( cAMP, cGMP and cAMP/cGMP value)...
September 2015: Zhong Yao Cai, Zhongyaocai, Journal of Chinese Medicinal Materials
Jun Panee
Bamboo plants play a significant role in traditional Asian medicine, especially in China and Japan. Biomedical investigations on the health-benefiting effects as well as toxicity of different parts and species of bamboo have been carried out worldwide since the 1960s, and documented a wide range of protective effects of bamboo-derived products, such as protection against oxidative stress, inflammation, lipotoxicity, cancer, and cardiovascular disease. Some of these products may interfere with male and female reproductive function, thyroid hormone metabolism, and hepatic xenobiotransformation enzymes...
June 2015: Journal of Medicinal Plant Research
Hiroki Shimura
Since the accidents at the Fukushima Daiichi Nuclear Power Plant after the Great East Japan Earthquake on March 11, 2011, large quantities of radionuclides have leaked into the surrounding environment. Fukushima Prefecture started the Fukushima Health Management Survey Project including Thyroid Ultrasound Examination to screen for thyroid cancer in all residents aged 0 to 18 years at the time of the nuclear accident. This accident also led to increased interest in thyroid ultrasound examination in Japan. This article reviews the studies to establish ultrasound diagnostic criteria for thyroid nodules and the clinical guidelines of thyroid nodule management, both of which are fundamental to Thyroid Ultrasound Examination in Fukushima...
March 2015: Rinsho Byori. the Japanese Journal of Clinical Pathology
Afria Zaman, Md Shamsuddin Sultan Khan, Lucky Akter, Sharif Hossain Syeed, Jakia Akter, Abdullah Al Mamun, Md Ershad Alam, Md Ahsan Habib, Md Abdul Jalil
BACKGROUND: Nidrakar Bati (NKB) is an herbal remedy consisted with seven medicinal herbs widely used to cure Somnifacient (sleeping aid) in South Asia as Ayurvedic medicinal system. In the present study, pharmacological and toxicological effects of this medicine was investigated in mice to validate the safety and efficacy of the herb. METHODS: Organic solvent extracts NKB were prepared using maceration method. Effect of extracts on the central nervous system was evaluated using hypnotic activity assay...
April 16, 2015: BMC Complementary and Alternative Medicine
A V Kaminskiĭ, I A Kiseleva, E V Teplaia
Available data on the effect of various trace elements on iodine metabolism and function of thyroid gland (TG) were systematized in this article. Subsequently, promising possibilities of herbal therapy in treatment and prevention of TG diseases were considered. Systemic analyis of the results of 3 independent open-label clinical studies performed in accordance with requirements of evidence-based medicine that involved herbal medicinal product Alba® (root extract of white cinquefoil) was carried out. Therapeutic options of Alba® use in various TG pathologies were presented...
December 2013: Likars'ka Sprava
Rohit A Gupta, Meha N Motiwala, Nitin G Dumore, Kishor R Danao, Anjali B Ganjare
ETHNOPHARMACOLOGICAL RELEVANCE: Piperine, a main component of Piper longum Linn. and Piper nigrum Linn., is a plant alkaloid with a long history of medicinal use. Piperine exhibits antidepressant, hepatoprotective, anti-metastatic, anti-thyroid, immunomodulatory, antitumor and anti-inflammatory activities, However its therapeutic potential in amelioration of ulcerative colitis and the underlying mechanism for anti-inflammatory activity remains unknown.The objective of the present investigation was to unravel the therapeutic potential of piperine on amelioration of IBD using acetic acid induced experimental animal model for ulcerative colitis and to determine the role of TLR4 receptor in signalling pathway of inflammatory gene expression in ulcerative colitis...
April 22, 2015: Journal of Ethnopharmacology
Shirin Parvinroo, Farzaneh Naghibi, Saleh Zahediasl, Mohammad Kamalinejad, Masoumeh Sabetkasaei
ETHNOPHARMACOLOGICAL RELEVANCE: Hot and cold temperaments are the basic concepts of Iranian traditional medicine (ITM). Nevertheless, studies on the functional mechanisms of medicinal herbs based on hot and cold temperaments are not very extensive. This study aimed to evaluate the effects of diets containing hot or cold temperament seeds according to ITM on some hormonal and neuromediator parameters with a regulatory role in thermogenesis and energy metabolism in acute (24 hr) and subacute (7-day) experiments that were performed on rats...
October 28, 2014: Journal of Ethnopharmacology
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