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Peripheral Arterial Obstructive Disease

Botond Szucs, Mate Petrekanits, Janos Varga
Background: Chronic obstructive pulmonary disease (COPD) may have considerable cardiovascular risk. Physical activity has a paramount role in COPD treatment. Our aim was to evaluate the applicability of arteriograph in COPD and measure the effectiveness of pulmonary rehabilitation on endothelial function. Methods: A total of 40 patients with COPD (FEV1 : 45.43±20.20%pred, BMI: 27.99±6.98 kg/m2 , male: female was 21:19, age: 65.47±7.39 years) participated in a 4-week rehabilitation program...
December 2018: Journal of Thoracic Disease
Kota Sahara, Atsushi Ishibe, Taichi Yabuno, Hiroki Kondo, Gakuryu Nakayama, Shota Yasuda, Takahiro Nishida, Jun Watanabe, Yasuko Uranaka, Hirotoshi Akiyama, Akira Sugita, Itaru Endo
Background: Acute iliac arterial thrombosis during surgery is very rare complication. There were few reports on this complication relative to gastroenterological surgery, and the risk has not been recognized. Case presentation: A 70-year-old man, diagnosed with a rectal cancer (adenocarcinoma of rectum) with known history heavy cigarette smoking with no known history of peripheral vascular disease underwent a laparoscopic abdominoperineal resection. He presented severe pain in the left leg in the recovery room...
February 2019: Journal of Surgical Case Reports
Lucretia M Wiltz-James, James Foley
Peripheral disease affects both arteries and veins and encompasses pathophysiologic conditions that affect arterial, venous, and lymphatic circulations. This article discusses disorders of peripheral vascular disease (PVD) that affect the lower extremity. PVD is an obstruction in the arteries known as arteriosclerosis obliterans, a condition that manifests from insufficient tissue perfusion that results in hardening of the arteries. Peripheral artery disease leads to an inflammatory condition called atherosclerosis...
March 2019: Critical Care Nursing Clinics of North America
Nian-Sheng Tzeng, Chi-Hsiang Chung, Hsin-An Chang, Chuan-Chia Chang, Ru-Band Lu, Hui-Wen Yeh, Wei-Shan Chiang, Yu-Chen Kao, Shan-Yueh Chang, Wu-Chien Chien
STUDY OBJECTIVES: This study has investigated the risk of major adverse cardiovascular events (MACEs), including acute myocardial infarction, coronary artery disease, peripheral artery disease, and acute stroke, among children and adolescents (age younger than 20 years) with obstructive sleep apnea (OSA). METHODS: In this study, the population-based National Health Insurance Research Database of Taiwan was used to identify patients in whom OSA had been first diagnosed between 2000 and 2015...
February 4, 2019: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Tim Kaufeld, Eric Beckmann, Fabio Ius, Nurbol Koigeldiev, Wiebke Sommer, Bakr Mashaqi, Felix N Fleissner, Thierry Siemeni, Jacob Ono Puntigam, Jessica Kaufeld, Axel Haverich, Christian Kuehn
BACKGROUND: Venoarterial extracorporeal membrane oxygenation support is a well-established tool in the care of severe refractory cardiac and respiratory failure. The application of this support may serve as a bridge to transplant, recovery or to implantation of a ventricular assist device. Venoarterial extracorporeal membrane oxygenation support can be administered through an open surgical access via the common femoral or axillary artery or a percutaneous approach using Seldinger technique...
February 8, 2019: Perfusion
Daniel-Sebastian Dohle, Hazem El Beyrouti, Lena Brendel, Philipp Pfeiffer, Mohammed El-Mehsen, Christian-Friedrich Vahl
OBJECTIVES: Conventional treatment for acute type A dissection is the replacement of the ascending aorta. This study demonstrates the results of a conventional approach with isolated proximal repair combined with concomitant endovascular procedures. METHODS: Replacement of the ascending aorta with or without an open distal anastomosis was defined as isolated proximal repair and was performed in 562/588 patients between January 2004 and June 2017. A total of 68% were DeBakey type I and 32% were DeBakey type II aortic dissections...
February 2, 2019: Interactive Cardiovascular and Thoracic Surgery
Karsten Keller, Lukas Hobohm, Thomas Münzel, Mir Abolfazl Ostad, Christine Espinola-Klein
BACKGROUND: Peripheral artery disease (PAD) and chronic obstructive pulmonary disease (COPD) are both related with high in-hospital mortality. We aimed to investigate the impact of COPD on the in-hospital outcomes in PAD. METHODS: PAD patients were selected based on ICD-code I70.2 of the German nationwide database, stratified for COPD and compared regarding adverse in-hospital outcomes. RESULTS: Between 01/2005-12/2015, 5,611,827 inpatients (64...
February 2019: Respiratory Medicine
Navneet Sharma, Kathleen Stergiopoulos, Jie Yang, Donglei Yin, Puja B Parikh
BACKGROUND: A differential impact of sex has been observed in balloon aortic valvuloplasty (BAV) outcomes from small observational studies. Accordingly, we sought to compare mortality in men and women undergoing BAV and identify sex-specific predictors of mortality. METHODS: The Nationwide Inpatient Sample was screened for hospitalizations involving adults who underwent BAV between 2006 and 2014. Demographic data and clinical history were recorded. In-hospital mortality and predictors of death after BAV were assessed in men and women...
January 19, 2019: Cardiovascular Revascularization Medicine: Including Molecular Interventions
ZiMian Gao, Kaiyi Zhao, Hao Pan, Kui Chen, JiHang Zheng
PURPOSE: Spinal cord ischemia is a rare complication of endovascular repair of abdominal aortic aneurysm (AAA) that is attributed to the variable anatomy of the artery of Adamkiewicz, embolization of the collateral circulation, or hypoperfusion of cord structures secondary to hypotension. CASE REPORT: A hypertensive 83-year-old male with chronic obstructive pulmonary disease presented with a 2.3 cm right iliac artery dissecting aneurysm. Paraplegia occurred on the first day after endovascular repair of iliac artery aneurysm...
January 23, 2019: Annals of Vascular Surgery
Scott Kinlay, Mariah Bundy, Melissa Chin, Desiree Tobin, Margot Quinn, Jacquelyn-My Do, Shannon Johnson, Sara Temiyasathit, Samantha Ly
In healthy arteries, blood flow is regulated by microvascular tone assessed by changes in blood flow volume and vascular resistance to endothelium-dependent and -independent vasodilators. We developed a novel method of using intravascular ultrasound (IVUS) and a Doppler flow wire to measure changes in blood flow volume and vascular resistance of the profunda arterial bed. We assessed the variability over 6 months in measuring microvascular endothelium-dependent dilation to acetylcholine and endothelium-independent dilation to adenosine in 20 subjects who were part of a larger study of Gulf War Illness without obstructive peripheral artery disease...
2019: PloS One
Nathalie H P Claessens, Johannes M P J Breur, Floris Groenendaal, Roelie M Wösten-van Asperen, Raymond Stegeman, Felix Haas, Jeroen Dudink, Linda S de Vries, Nicolaas J G Jansen, Manon J N L Benders
BACKGROUND: Brain microstructural maturation progresses rapidly in the third trimester of gestation and first weeks of life, but typical microstructural development may be influenced by the presence of critical congenital heart disease (CHD). OBJECTIVE: The aim of this study was to investigate the pattern of white matter (WM) microstructural development in neonates with different types of critical CHD. The secondary aim was to examine whether there is an association between WM microstructural maturity and neonatal ischemic brain injury...
January 7, 2019: NeuroImage: Clinical
Clémence Palazzo, Renata T C Yokota, Jean Tafforeau, Jean-François Ravaud, Emmanuelle Cambois, Serge Poiraudeau, Herman Van Oyen, Wilma J Nusselder
Background: This study aimed 1) to assess whether the contribution of chronic conditions to disability varies according to the educational attainment, 2) to disentangle the contributions of the prevalence and of the disabling impact of chronic conditions to educational disparities. Methods: Data of the 2008-09 Disability Health Survey were examined ( N  = 23,348). The disability indicator was the Global Activity Limitation Indicator (GALI). The attribution method based on an additive hazard model was used to estimate educational differences in disabling impacts and in the contributions of diseases to disability...
2019: Archives of Public Health, Archives Belges de Santé Publique
Paweł Balsam, Krzysztof Ozierański, Agnieszka Kapłon-Cieślicka, Sonia Borodzicz, Agata Tymińska, Michał Peller, Michał Marchel, Maria G Crespo-Leiro, Aldo Pietro Maggioni, Jarosław Drożdż, Grzegorz Opolski, Marcin Grabowski
INTRODUCTION The management of heart failure (HF) has significantly changed in recent decades. OBJECTIVES The paper analyzes clinical profile, one-year outcomes, predictors of mortality and hospital readmissions in hospitalized patients enrolled in the European Society of Cardiology HF-Pilot (ESC-HF-Pilot) and HF-Long Term (ESC-HF-LT) Registries. PATIENTS AND METHODS The analysis included hospitalized Polish patients from the ESC-HF-Pilot and ESC-HF-LT Registries. The primary endpoint (PE) was all-cause death at one year, whereas the secondary endpoint (SE) consisted of all-cause death or hospitalization for worsening HF at one year...
January 16, 2019: Polish Archives of Internal Medicine
Xiufang Wang, Juyi Li, Liming Gan, Qun Liu
Critical limb ischemia (CLI) is a serious arterial obstruction, resulting in serious reduction of blood flow to the extremities. CLI is a symptomatic disorder and is frequently not diagnosed in time. This results in a high mortality and elevated risk of limb amputation. Serum or plasma biomarkers play important roles in disease prevention, diagnosis, and prognosis. Elevated plasma neutrophil-activating peptide-2 (NAP-2) was found independently associated with CLI, but not with T2DM. Plasma NAP-2 levels might be an early CLI diagnostic biomarker and might provide a novel target for CLI treatment...
January 12, 2019: Experimental Biology and Medicine
Yu Wang, Na Liu, Zhecheng Zhang
Respiratory failure is common during acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). Phrenic nerve conduction (PNC), transcranial magnetic stimulation (TMS), and cervical magnetic stimulation (CMS) are of great value in identifying the feature and site of AE-COPD.PNC, TMS, and CMS were performed in 20 AE-COPD patients with respiratory failure, and re-examined after weaning. Latencies and amplitudes of the diaphragmatic compound muscle action potential (dCMAP), motor evoked potential of the diaphragm (dMEP) evoked by TMS and CMS, and central motor conduction time (CMCT) were measured...
January 2019: Medicine (Baltimore)
Natalie Terzikhan, Lies Lahousse, Katia M C Verhamme, Oscar H Franco, Arfan M Ikram, Bruno H Stricker, Guy G Brusselle
Patients with chronic obstructive pulmonary disease (COPD) commonly present with multimorbidity. We aimed to investigate the association between COPD and the development of peripheral arterial disease (PAD) in the general population, and how this might affect mortality among individuals with COPD. We included 3123 participants of the population-based Rotterdam Study without PAD at baseline (mean age 65 years; 57.4% female). The association between COPD at baseline and PAD during follow-up was studied using logistic regression (PAD being indicated by an ankle-brachial index (ABI) of 0...
October 2018: ERJ Open Research
Salvatore T Scali, Diego Ayo, Kristina A Giles, Sarah Gray, Paul Kubilis, Martin Back, Javairiah Fatima, Dean Arnaoutakis, Scott A Berceli, Adam W Beck, Gilbert J Upchurch, Robert J Feezor, Thomas S Huber
BACKGROUND: Acute mesenteric ischemia (AMI) is a challenging clinical problem associated with significant morbidity and mortality. Few contemporary reports focus specifically on patients undergoing open mesenteric bypass (OMB) or delineate outcome differences based on bypass configuration. This is notable, because there is a subset of patients who are poor candidates for endovascular intervention including those with flush mesenteric vessel occlusion, long segment occlusive disease, and a thrombosed mesenteric stent and/or bypass...
January 2019: Journal of Vascular Surgery
Heidi T May, Donald L Lappé, Kirk U Knowlton, Joseph B Muhlestein, Jeffrey L Anderson, Benjamin D Horne
OBJECTIVE: To apply the practical parsimonious modeling method of the Intermountain Mortality Risk Score in a primary care environment to predict chronic disease (ChrD) onset. PATIENTS AND METHODS: Primary care patients free of ChrD (women: n=98,711; men: n=45,543) were evaluated to develop (70% [n=95,882] of patients) and validate (the other 30% [n=48,372]) the sex-specific Intermountain Chronic Disease Risk Score (ICHRON) if seen initially between January 1, 2003, and December 31, 2005...
December 18, 2018: Mayo Clinic Proceedings
T Othman, H Tun, J S Bainiwal, E S Andersen, N L Dharmavaram, W S Schwartzman, A N Baffo, B C Butera, N S Phuong, P Z Xu, B Yasmeh, N A Gertsvolf, A J Yoon, D M Shavelle, P K Garg, H M Van Herle, J A Kahn, B Kim
Incidental arterial calcification (Ca) on low-dose computed tomography (CT) prior to liver transplant (LT) may help identify those at risk for obstructive coronary artery disease (CAD). A single-center retrospective study of 358 consecutive patients who had undergone LT was performed. Of the 296 patients who met inclusion criteria, 193 patients (65.2%) had CT Ca. Aortic Ca was seen in 116 (39.2%), coronary Ca in 141 (47.6%), and peripheral Ca in 8 patients (2.7%). Patients with coronary Ca were assigned ordinal coronary artery Ca scores and classified as mild, moderate, and severe...
December 2018: Transplantation Proceedings
Nicolas W Shammas, Pradeep Chandra, Marianne Brodmann, Barry Weinstock, Gino Sedillo, Ian Cawich, Antonio Micari, Arthur Lee, Chris Metzger, Luis Mariano Palena, John Rundback
BACKGROUND: B-Laser™ is a novel atherectomy device that uses a solid-state third harmonic pulsed Nd:YAG laser with an output of 355 nm. Early data showed that the B-Laser™ is safe in treating a broad range of infrainguinal arterial lesions. We present the results of the EX-PAD-03 U.S. pivotal trial of the EXIMO B-Laser™. METHODS: EX-PAD-03 is a prospective, single-arm, multi-center, international, open-label, clinical study. The study enrolled patients in the United States and Europe...
November 29, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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