Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Mateusz Polak, Joanna Wieczorek, Malwina Botor, Aleksandra Auguścik-Duma, Andrzej Hoffmann, Anna Wnuk-Wojnar, Katarzyna Gawron, Katarzyna Mizia-Stec
Background: MicroRNA (miRNA) have the potential to be non-invasive and attractive biomarkers for a vast number of diseases and clinical conditions; however, a reliable analysis of miRNA expression in blood samples meets a number of methodological challenges. In this report, we presented and discussed, specifically, the principles and limitations of miRNA purification and analysis in blood plasma samples collected from the left atrium during an ablation procedure on patients with atrial fibrillation (AF). Materials and Methods: Consecutive patients hospitalized in the First Department of Cardiology for pulmonary vein ablation were included in this study (11 with diagnosed paroxysmal AF, 14 with persistent AF, and 5 without AF hospitalized for left-sided WPW ablation-control group)...
March 25, 2024: Journal of Clinical Medicine
#2
JOURNAL ARTICLE
Nicolas Branger, Nicolas Doumerc, Thibaut Waeckel, Pierre Bigot, Louis Surlemont, Sophie Knipper, Géraldine Pignot, François Audenet, Frank Bruyère, Alexis Fontenil, Bastien Parier, Cécile Champy, Morgan Rouprêt, Jean-Jacques Patard, François Henon, Gaëlle Fiard, Julien Guillotreau, Jean-Baptiste Beauval, Constance Michel, Simon Bernardeau, Fayek Taha, Richard Mallet, Frederic Panthier, Laurent Guy, Louis Vignot, Zine-Eddine Khene, Jean-Christophe Bernhard
BACKGROUND AND OBJECTIVE: Data regarding open conversion (OC) during minimally invasive surgery (MIS) for renal tumors are reported from big databases, without precise description of the reason and management of OC. The objective of this study was to describe the rate, reasons, and perioperative outcomes of OC in a cohort of patients who underwent MIS for renal tumor initially. The secondary objective was to find the factors associated with OC. METHODS: Between 2008 and 2022, of the 8566 patients included in the UroCCR project prospective database (NCT03293563), who underwent laparoscopic or robot-assisted minimally invasive partial (MIPN) or radical (MIRN) nephrectomy, 163 experienced OC...
May 2024: European urology open science
#3
JOURNAL ARTICLE
Tiancheng Pu, Adhika Setiawan, Alexandre C Foucher, Mingyu Guo, Jih-Mirn Jehng, Minghui Zhu, Michael E Ford, Eric A Stach, Srinivas Rangarajan, Israel E Wachs
The oxygen species on Ag catalysts and reaction mechanisms for ethylene epoxidation and ethylene combustion continue to be debated in the literature despite decades of investigation. Fundamental details of ethylene oxidation by supported Ag/α-Al2 O3 catalysts were revealed with the application of high-angle annular dark-field-scanning transmission electron microscopy-energy-dispersive X-ray spectroscopy (HAADF-STEM-EDS), in situ techniques (Raman, UV-vis, X-ray diffraction (XRD), HS-LEIS), chemical probes (C2 H4 -TPSR and C2 H4 + O2 -TPSR), and steady-state ethylene oxidation and SSITKA (16 O2 → 18 O2 switch) studies...
January 5, 2024: ACS Catalysis
#4
JOURNAL ARTICLE
Renhe Jiao, Boqiong Wu, Senrong Han, Dongyao Cui, Jingxian Sun, Tanjun Zhao, Yaoyao Zhan, Yaqing Chang
The microRNA novel-3 (miRn-3) is a 23-nt small endogenous noncoding RNA of unknown function. To enrich our knowledge of the regulatory function of miRn-3 in the process of wound healing, the sea cucumber Apostichopus japonicus was used as a target model in this study. Gelsolin (AjGSN), a potential target gene of miRn-3, was cloned and characterized, and the interaction between miRn-3 and AjGSN was verified. The function of the miRn-3/AjGSN axis in regulating cutaneous wound healing was explored in the sea cucumber A...
October 31, 2023: International Journal of Biological Macromolecules
#5
REVIEW
Bashdar Mahmud Hussen, Majid Noori, Babak Sayad, Maryam Ebadi Fard Azar, Javid Sadri Nahand, Mobina Bayat, Farhad Babaei, Romina Karampour, Farah Bokharaei-Salim, Hamed Mirzaei, Mohsen Moghoofei, Hossein Bannazadeh Baghi
INTRODUCTION: This research aimed to evaluate the specific miRNA including miR-17-5p, miRN-140-3p miR-191-5p, miR-200c-3p, and miR-N367 and cellular factors (p21, SDF-1, XCL1, CCL-2 and IL-2) in controlling replication of HIV in ECs. METHODS: The expression of miRNAs was assessed between healthy control groups and patient groups including ART-naïve HIV, HIV ART, ECs, and co-infection (HIV-HBV and HIV-HCV) via real-time PCR technique. Besides, the expression level of the nef gene and cellular factors were assessed by the ELISA method...
September 12, 2023: Intervirology
#6
JOURNAL ARTICLE
Mohanasundaram Avudiappan, Venu Bhargava, Aditya Kulkarni, Mandeep Kang, Surinder Singh Rana, Rajesh Gupta
BACKGROUND: The conventional open necrosectomy was associated with high mortality and morbidities like secondary organ failure, incisional hernia, enterocutaneous fistula, and external pancreatic fistula. In acute pancreatitis, collections are primarily confined to the retroperitoneal space. Hence, the retroperitoneal approach can be used to drain the collection and necrotic material. It benefits smaller incisions and better outcomes in terms of morbidity and mortality than the conventional open necrosectomy...
September 2023: Surgery open science
#7
JOURNAL ARTICLE
Xiliang Zhang, Jin Liu, Siwei Chang, Peizhu Gong, Zhongdai Wu, Bing Han
Vector-based retrieval have been widely adopted to process online users' diverse interests for recommendations. However, most of them utilize a single vector to represent user multiple interests (UMI), inevitably impairing the accuracy and diversity of item retrieval. In addition, existing work often does not take into account the scale and speed of the model, and high-dimensional user representation vectors need high computation cost, leading to inefficient item retrieval. In this paper, we propose a novel lightweight multi-interest retrieval network (MIRN) by incorporating sequence-to-interest Expectation Maximization (EM) routing to deal with users' multiple interests...
2023: PloS One
#8
REVIEW
Safa Baris, Hassan Abolhassani, Michel J Massaad, Maryam Al-Nesf, Zahra Chavoshzadeh, Sevgi Keles, Ismail Reisli, Azzeddine Tahiat, Hiba Mohammad Shendi, Dalia Abd Elaziz, Brahim Belaid, Fatima Al Dhaheri, Sule Haskologlu, Figen Dogu, Imen Ben-Mustapha, Ali Sobh, Nermeen Galal, Safa Meshaal, Rabab Elhawary, Aisha El-Marsafy, Fayhan J Alroqi, Bandar Al-Saud, Mona Al-Ahmad, Tariq Al Farsi, Nashat Al Sukaiti, Salem Al-Tamemi, Cybel Mehawej, Ghassan Dbaibo, Gehad ElGhazali, Sara Sebnem Kilic, Ferah Genel, Ayca Kiykim, Ugur Musabak, Hasibe Artac, Sukru Nail Guner, Rachida Boukari, Reda Djidjik, Nadia Kechout, Deniz Cagdas, Zeinab Awad El-Sayed, Elif Karakoc-Aydiner, Raed Alzyoud, Mohamed Ridha Barbouche, Mehdi Adeli, Rima Hanna Wakim, Shereen M Reda, Aydan Ikinciogullari, Ahmet Ozen, Aziz Bousfiha, Hamoud Al-Mousa, Nima Rezaei, Waleed Al-Herz, Raif S Geha
Human inborn errors of immunity (IEI) are a group of 485 distinct genetic disorders affecting children and adults. Signs and symptoms of IEI are heterogeneous, and accurate diagnosis can be challenging and depends on the available human expertise and laboratory resources. The Middle East and North Africa (MENA) region has an increased prevalence of IEI because of the high rate of consanguinity with a predominance of autosomal recessive disorders. This area also exhibits more severe disease phenotypes compared with other regions, probably due to the delay in diagnosis...
January 2023: Journal of Allergy and Clinical Immunology in Practice
#9
JOURNAL ARTICLE
Marta Balog, Allison Anderson, Channabasavaiah B Gurumurthy, Rolen M Quadros, Zeljka Korade, Karoly Mirnics
BACKGROUND: Somatostatin (SST) and cholecystokinin (CCK) are peptide hormones that regulate the endocrine system, cell proliferation and neurotransmission. NEW METHOD: We utilized the novel Easi-CRISPR system to generate two knock-in mouse strains with Cre recombinase in SST- and CCK-expressing cells and validated their utility in the developing and adult brain tissues. RESULTS: The full nomenclature for the newly generated strains are C57BL/6-Sstem1(P2A-iCre-T2A-mCherry)Mirn and C57BL/6-Cckem1(iCre-T2A-mCherry-P2A)Mirn ...
November 1, 2022: Journal of Neuroscience Methods
#10
JOURNAL ARTICLE
Krishna Teja Ravivarapu, Evan Garden, Chih Peng Chin, Micah Levy, Osama Al-Alao, Joseph Sewell-Araya, Alexander Small, Reza Mehrazin, Michael Palese
PURPOSE: Minimally invasive partial nephrectomy (MIPN) and radical nephrectomy (MIRN) have successfully resulted in shorter length of stay (LOS) for patients. Using a national cohort, we compared 30-day outcomes of SDD (LOS = 0) versus standard-length discharge (SLD, LOS = 1-3) for MIRN and MIPN. METHODS: All patients who underwent MIPN (CPT 50,543) or MIRN (CPT 50,545) in the ACS-NSQIP database from 2012 to 2019 were reviewed. SDD and SLD groups were matched 1:1 by age, sex, race, body mass index, American Society of Anesthesiologists score, and medical comorbidities...
July 30, 2022: World Journal of Urology
#11
JOURNAL ARTICLE
Patrick Leopold Rüther, Immanuel Mirnes Husic, Pernille Bangsgaard, Kristian Murphy Gregersen, Pernille Pantmann, Milena Carvalho, Ricardo Miguel Godinho, Lukas Friedl, João Cascalheira, Alberto John Taurozzi, Marie Louise Schjellerup Jørkov, Michael M Benedetti, Jonathan Haws, Nuno Bicho, Frido Welker, Enrico Cappellini, Jesper Velgaard Olsen
Species determination based on genetic evidence is an indispensable tool in archaeology, forensics, ecology, and food authentication. Most available analytical approaches involve compromises with regard to the number of detectable species, high cost due to low throughput, or a labor-intensive manual process. Here, we introduce "Species by Proteome INvestigation" (SPIN), a shotgun proteomics workflow for analyzing archaeological bone capable of querying over 150 mammalian species by liquid chromatography-tandem mass spectrometry (LC-MS/MS)...
May 5, 2022: Nature Communications
#12
JOURNAL ARTICLE
Pei-Chuan Hsu, Fang-Ming Hwang, Mei-I Chien, Wui-Chiu Mui, Jyh-Mirn Lai
There was a lack of detailed information about maternal influences on their children's body mass index (BMI) in Taiwan. The aim of this study was to find the evidence to describe how mothers' factors could affect their 2 to 9-year-old children's BMI, with data collected from May 2021 to June 2021. Anonymous self-administered questionnaires were completed by 1035 participants from Taiwan's six metropolitan cities and eight counties. After controlling for children's factors, such as number of children in a family, children's constitution, children's age and gender, hierarchical regression models were used to analyze the effects of five maternal factors on their children's BMI: maternal BMI, age, education level, monthly household income, and marital status (single parent or not)...
April 15, 2022: Scientific Reports
#13
JOURNAL ARTICLE
Heng-Ching Lin, Chishih Chu, Yaochi Su, Jyh-Mirn Lai
The National Bovine Tuberculosis (bTB) Eradication Program for dairy cattle has been operating in Taiwan for many years and has allowed the prevalence of bTB to decrease gradually. However, 29% of intradermal tuberculin test (ITT)-positive dairy cows were later found to be TB negative based on necropsy, histopathological examination, and mycobacterial isolation results. Studies in Taiwan have indicated that Mycobacterium avium subsp. paratuberculosis (MAP) may lead to false-positive ITT. Due to the high prevalence (over 90%) of paratuberculosis (PTB) serum antibody among Taiwan's farms, comparative ITT (CITT) has been recommended to differentiate between bTB and PTB infections...
January 26, 2022: Tropical Animal Health and Production
#14
JOURNAL ARTICLE
Sara Lpez-Prez, Geovanni M Rodrguez-Mirn, Caroline S Chaboo
Pupal morphology has been described for 11 species in six genera of the Neotropical tortoise beetle tribe, Ischyrosonychini Chapuis, 1875. This life stage may offer valuable phylogenetic information but more pupae need to be documented. The pupae of Physonota humilis Boheman, 1856 and P. stigmatilis Boheman, 1854 are described and illustrated for the first time. The pupa of P. humilis does not exhibit lateral scoli on the abdominal segments. Additionally, the body surfaces of P. humilis and P. stigmatilis are somewhat tuberculate, different from other described Physonota Boheman, 1854 pupae...
August 30, 2021: Zootaxa
#15
JOURNAL ARTICLE
Syed Muhammad Muntazir Mehdi, Sivakumar Krishnamoorthy, Michal Wojciech Szczesniak, Agnieszka Ludwików
miRNAs are involved in various biological processes, including adaptive responses to abiotic stress. To understand the role of miRNAs in the response to ABA, ABA-responsive miRNAs were identified by small RNA sequencing in wild-type Arabidopsis , as well as in abi1td , mkkk17 , and mkkk18 mutants. We identified 10 novel miRNAs in WT after ABA treatment, while in abi1td , mkkk17 , and mkkk18 mutants, three, seven, and nine known miRNAs, respectively, were differentially expressed after ABA treatment. One novel miRNA (miRn-8) was differentially expressed in the mkkk17 mutant...
July 1, 2021: International Journal of Molecular Sciences
#16
JOURNAL ARTICLE
Kyle Johnson, Brian R Lane, Alon Z Weizer, Lindsey A Herrel, Craig G Rogers, Ji Qi, Anna M Johnson, Brian D Seifman, Richard C Sarle
OBJECTIVES: To examine length of stay (LOS) and readmission rates for all minimally-invasive partial nephrectomy (MIPN) and MI radical nephrectomy (MIRN) performed for localized renal masses ≤7 cm in size (cT1RM) within 12 Michigan urology practices. Both RN and PN are commonly performed in treating cT1RM. Although technically more complex and associated with higher complication rates, Centers for Medicare & Medicaid Services considers MIPN an outpatient procedure and MIRN is inpatient...
January 20, 2021: Urologic Oncology
#17
JOURNAL ARTICLE
Shou-Heng Chiang, Han Hsiang Huang, Chi-Chung Chou, Chi-Shih Chu, Wen-Ling Shih, Jyh-Mirn Lai, Heng-Ching Lin, Wei-Cheng Yang, Hsu-Hsun Lee, Yi-Lun Tsai, Yao-Chi Su
Toxoplasma gondii and Neospora caninum are intracellular protozoan parasites that cause reproductive disorders in ruminants and humans. Information on the risk factors of T. gondii and N. caninum infections in goats is very limited in Taiwan. The aim of the study was to investigate the epidemiology and identify the risk factors of these two infections in goats. A total of 630 caprine sera were collected from 42 dairy goat farms and the owners were interviewed by a structured questionnaire. The apparent seroprevalences of T...
September 4, 2020: Journal of Veterinary Medical Science
#18
JOURNAL ARTICLE
Ming-Yang Tsai, Chang-Hsun Ho, Hong-You Chang, Wei-Cheng Yang, Chuen-Fu Lin, Chien-Teng Lin, Yi-Jing Xue, Jyh-Mirn Lai, Jiann-Hsiung Wang, Geng-Ruei Chang
Phthalates are widely used plasticizers that can cause endocrine disruption, mutagenicity, and carcinogenic effects and can contaminate food through various pathways. Investigations are scanty on phthalate pollution of livestock and poultry meat and their dietary exposure to humans. The present study assessed residual levels of phthalates in unpackaged pork (30 samples) and unpackaged chicken (30 samples) and their relevance to meat consumption and health risks in the Taiwanese population. Phthalate quantity was assessed by liquid chromatography-tandem mass spectrometry; the materials included diisononyl phthalate, diisodecyl phthalate, benzyl butyl phthalate, di-2-ethylhexyl phthalate (DEHP), and di-n-butyl phthalate...
October 23, 2019: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
#19
JOURNAL ARTICLE
Sun-A Ock, Inchul Choi, Gi-Sun Im, Jae Gyu Yoo
Reproductive cloning by somatic cell nuclear transfer (SCNT) is a valuable method to propagate service dogs with desirable traits because of higher selection rates in cloned dogs. However, incomplete reprogramming is a major barrier to SCNT, and the assessment of reprogramming is limited to preimplantation embryos and tissues from dead and/or adult tissue. Thus, lifelong monitoring in SCNT dogs can be useful to evaluate the SCNT service dogs for propagation. We applied microarray and qRT-PCR to profile of mRNA and miRNA in whole blood samples collected from four cloned dogs (S), three age-matched control dogs (A), and a donor dog (D)...
December 2019: Cellular Reprogramming
#20
JOURNAL ARTICLE
Menha Swellam, Rasha F K Zahran, Samar Ayman Ghonem, Camelia Abdel-Malak
Background: Accumulating evidence reveals that microRNA 27a (miR 27a) is implicated in the pathogenesis of cancer. However, its diagnostic role in breast cancer (BC) still needs investigation. Materials and methods: MiR 27a expression was assessed in serum samples from patients with primary BC ( n = 100), benign breast lesions ( n = 30) and control group served as healthy volunteers ( n = 20) using quantitative real-time PCR. Results: Both expression and mean rank of miR 27a and tumor markers among BC patients as compared to the other two groups...
May 30, 2019: Archives of Physiology and Biochemistry
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
