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Daniel Lichtenstein

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https://read.qxmd.com/read/30872018/current-misconceptions-in-lung-ultrasound-a-short-guide-for-experts
#1
Daniel A Lichtenstein
No abstract text is available yet for this article.
March 11, 2019: Chest
https://read.qxmd.com/read/30863935/lung-ultrasound-allows-the-diagnosis-of-weaning-induced-pulmonary-oedema
#2
Alexis Ferré, Max Guillot, Daniel Lichtenstein, Gilbert Mezière, Christian Richard, Jean-Louis Teboul, Xavier Monnet
RATIONALE: Detecting weaning-induced pulmonary oedema (WIPO) is important because its treatment might prompt extubation. For this purpose, lung ultrasound might be an attractive tool, since it demonstrates pulmonary oedema through the appearance of B-lines. OBJECTIVES: To test the ideal profile (increase in the number of B-lines) for diagnosing WIPO. METHODS: Before and at the end of 62 spontaneous breathing trials (SBT) performed in 42 patients, we prospectively assessed lung ultrasound on four anterior chest wall points...
March 12, 2019: Intensive Care Medicine
https://read.qxmd.com/read/30859356/visual-disengagement-genetic-architecture-and-relation-to-autistic-traits-in-the-general-population
#3
Monica Siqueiros Sanchez, Erik Pettersson, Daniel P Kennedy, Sven Bölte, Paul Lichtenstein, Brian M D'Onofrio, Terje Falck-Ytter
Visual disengagement has been hypothesized as an endophenotype for autism. In this study we used twin modelling to assess the role of genetics in basic measures of visual disengagement, and tested their putative association to autistic traits in the general population. We used the Gap Overlap task in a sample of 492 twins. Results showed that most of the covariance among eye movement latencies across conditions was shared and primarily genetic. Further, there were unique genetic contributions to the Gap condition, but not to the Overlap condition-i...
March 11, 2019: Journal of Autism and Developmental Disorders
https://read.qxmd.com/read/30818255/ghrelin-and-aggressive-behaviours-evidence-from-preclinical-and-human-genetic-studies
#4
Jesper Vestlund, Julia Winsa-Jörnulf, Daniel Hovey, Sebastian Lundström, Paul Lichtenstein, Henrik Anckarsäter, Erik Studer, Petra Suchankova, Lars Westberg, Elisabet Jerlhag
Aggressive behaviour is of crucial importance in the defence for limited resources including food and mates and involves central serotonin as well as dopamine signalling. As ghrelin modulates food intake and sexual behaviour we initially investigated the hypothesis that central ghrelin signalling regulates aggressive behaviour in the resident intruder paradigm in male mice. Moreover, interaction between ghrelin signalling and serotonergic, noradrenergic as well as dopaminergic neurotransmission in aggression was investigated...
February 20, 2019: Psychoneuroendocrinology
https://read.qxmd.com/read/30796027/a-peripheral-blood-dna-methylation-signature-of-hepatic-fat-reveals-a-potential-causal-pathway-for-non-alcoholic-fatty-liver-disease
#5
Jiantao Ma, Jana Nano, Jingzhong Ding, Yinan Zheng, Rachel Hennein, Chunyu Liu, Elizabeth K Speliotes, Tianxiao Huan, Ci Song, Michael M Mendelson, Roby Joehanes, Michelle T Long, Liming Liang, Jennifer A Smith, Lindsay Reynolds, Mohsen Ghanbari, Taulant Muka, Joyce van Meurs, Louise J M Alferink, Oscar H Franco, Abbas Dehghan, Scott Ratliff, Wei Zhao, Lawrence Bielak, Sharon Lr Kardia, Patricia A Peyser, Hongyan Ning, Lisa B VanWagner, Donald M Lloyd-Jones, John Jeffrey Carr, Philip Greenland, Alice H Lichtenstein, Frank B Hu, Yongmei Liu, Lifang Hou, Sarwa Darwish Murad, Daniel Levy
Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes. We aimed to identify the peripheral blood DNA methylation signature of hepatic fat. We conducted epigenome-wide association studies of hepatic fat in 3,400 European ancestry (EA) participants and in 401 Hispanic ancestry and 724 African ancestry participants from four population-based cohort studies. Hepatic fat was measured using computed tomography or ultrasound imaging and DNA methylation was assessed at over 400,000 cytosine-guanine dinucleotides (CpGs) in whole blood or CD14+ monocytes using a commercial array...
February 22, 2019: Diabetes
https://read.qxmd.com/read/30707296/habitat-structure-changes-the-relationships-between-predator-behavior-prey-behavior-and-prey-survival-rates
#6
James L L Lichtenstein, Karis A Daniel, Joanna B Wong, Colin M Wright, Grant Navid Doering, Raul Costa-Pereira, Jonathan N Pruitt
The individual behavioral traits of predators and prey sometimes determine the outcome of their interactions. Here, we examine whether changes to habitat complexity alter the effects of predator and prey behavior on their survival rates. Specifically, we test whether behavioral traits (activity level, boldness, and perch height) measured in predators and prey or multivariate behavioral volumes best predict the survival rates of both trophic levels in staged mesocosms with contrasting structural complexity. Behavioral volumes and hypervolumes are a composite group-level behavioral diversity metric built from the individual-level behavioral traits we measured in predators and prey...
February 1, 2019: Oecologia
https://read.qxmd.com/read/30683625/contributions-of-traditional-and-hiv-related-risk-factors-on-non-aids-defining-cancer-myocardial-infarction-and-end-stage-liver-and-renal-diseases-in-adults-with-hiv-in-the-usa-and-canada-a-collaboration-of-cohort-studies
#7
Keri N Althoff, Kelly A Gebo, Richard D Moore, Cynthia M Boyd, Amy C Justice, Cherise Wong, Gregory M Lucas, Marina B Klein, Mari M Kitahata, Heidi Crane, Michael J Silverberg, M John Gill, William Christopher Mathews, Robert Dubrow, Michael A Horberg, Charles S Rabkin, Daniel B Klein, Vincent Lo Re, Timothy R Sterling, Fidel A Desir, Kenneth Lichtenstein, James Willig, Anita R Rachlis, Gregory D Kirk, Kathryn Anastos, Frank J Palella, Jennifer E Thorne, Joseph Eron, Lisa P Jacobson, Sonia Napravnik, Chad Achenbach, Angel M Mayor, Pragna Patel, Kate Buchacz, Yuezhou Jing, Stephen J Gange
BACKGROUND: Adults with HIV have an increased burden of non-AIDS-defining cancers, myocardial infarction, end-stage liver disease, and end-stage renal disease. The objective of this study was to estimate the population attributable fractions (PAFs) of preventable or modifiable HIV-related and traditional risk factors for non-AIDS-defining cancers, myocardial infarction, end-stage liver disease, and end-stage renal disease outcomes. METHODS: We included participants receiving care in academic and community-based outpatient HIV clinical cohorts in the USA and Canada from Jan 1, 2000, to Dec 31, 2014, who contributed to the North American AIDS Cohort Collaboration on Research and Design and who had validated non-AIDS-defining cancers, myocardial infarction, end-stage liver disease, or end-stage renal disease outcomes...
February 2019: Lancet HIV
https://read.qxmd.com/read/30482948/transancestral-gwas-of-alcohol-dependence-reveals-common-genetic-underpinnings-with-psychiatric-disorders
#8
Raymond K Walters, Renato Polimanti, Emma C Johnson, Jeanette N McClintick, Mark J Adams, Amy E Adkins, Fazil Aliev, Silviu-Alin Bacanu, Anthony Batzler, Sarah Bertelsen, Joanna M Biernacka, Tim B Bigdeli, Li-Shiun Chen, Toni-Kim Clarke, Yi-Ling Chou, Franziska Degenhardt, Anna R Docherty, Alexis C Edwards, Pierre Fontanillas, Jerome C Foo, Louis Fox, Josef Frank, Ina Giegling, Scott Gordon, Laura M Hack, Annette M Hartmann, Sarah M Hartz, Stefanie Heilmann-Heimbach, Stefan Herms, Colin Hodgkinson, Per Hoffmann, Jouke Jan Hottenga, Martin A Kennedy, Mervi Alanne-Kinnunen, Bettina Konte, Jari Lahti, Marius Lahti-Pulkkinen, Dongbing Lai, Lannie Ligthart, Anu Loukola, Brion S Maher, Hamdi Mbarek, Andrew M McIntosh, Matthew B McQueen, Jacquelyn L Meyers, Yuri Milaneschi, Teemu Palviainen, John F Pearson, Roseann E Peterson, Samuli Ripatti, Euijung Ryu, Nancy L Saccone, Jessica E Salvatore, Sandra Sanchez-Roige, Melanie Schwandt, Richard Sherva, Fabian Streit, Jana Strohmaier, Nathaniel Thomas, Jen-Chyong Wang, Bradley T Webb, Robbee Wedow, Leah Wetherill, Amanda G Wills, Jason D Boardman, Danfeng Chen, Doo-Sup Choi, William E Copeland, Robert C Culverhouse, Norbert Dahmen, Louisa Degenhardt, Benjamin W Domingue, Sarah L Elson, Mark A Frye, Wolfgang Gäbel, Caroline Hayward, Marcus Ising, Margaret Keyes, Falk Kiefer, John Kramer, Samuel Kuperman, Susanne Lucae, Michael T Lynskey, Wolfgang Maier, Karl Mann, Satu Männistö, Bertram Müller-Myhsok, Alison D Murray, John I Nurnberger, Aarno Palotie, Ulrich Preuss, Katri Räikkönen, Maureen D Reynolds, Monika Ridinger, Norbert Scherbaum, Marc A Schuckit, Michael Soyka, Jens Treutlein, Stephanie Witt, Norbert Wodarz, Peter Zill, Daniel E Adkins, Joseph M Boden, Dorret I Boomsma, Laura J Bierut, Sandra A Brown, Kathleen K Bucholz, Sven Cichon, E Jane Costello, Harriet de Wit, Nancy Diazgranados, Danielle M Dick, Johan G Eriksson, Lindsay A Farrer, Tatiana M Foroud, Nathan A Gillespie, Alison M Goate, David Goldman, Richard A Grucza, Dana B Hancock, Kathleen Mullan Harris, Andrew C Heath, Victor Hesselbrock, John K Hewitt, Christian J Hopfer, John Horwood, William Iacono, Eric O Johnson, Jaakko A Kaprio, Victor M Karpyak, Kenneth S Kendler, Henry R Kranzler, Kenneth Krauter, Paul Lichtenstein, Penelope A Lind, Matt McGue, James MacKillop, Pamela A F Madden, Hermine H Maes, Patrik Magnusson, Nicholas G Martin, Sarah E Medland, Grant W Montgomery, Elliot C Nelson, Markus M Nöthen, Abraham A Palmer, Nancy L Pedersen, Brenda W J H Penninx, Bernice Porjesz, John P Rice, Marcella Rietschel, Brien P Riley, Richard Rose, Dan Rujescu, Pei-Hong Shen, Judy Silberg, Michael C Stallings, Ralph E Tarter, Michael M Vanyukov, Scott Vrieze, Tamara L Wall, John B Whitfield, Hongyu Zhao, Benjamin M Neale, Joel Gelernter, Howard J Edenberg, Arpana Agrawal
Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders. To discover loci associated with AD and characterize the relationship between AD and other psychiatric and behavioral outcomes, we carried out the largest genome-wide association study to date of DSM-IV-diagnosed AD. Genome-wide data on 14,904 individuals with AD and 37,944 controls from 28 case-control and family-based studies were meta-analyzed, stratified by genetic ancestry (European, n = 46,568; African, n = 6,280)...
December 2018: Nature Neuroscience
https://read.qxmd.com/read/30409330/lung-ultrasound-for-the-cardiologist
#9
REVIEW
Eugenio Picano, Maria Chiara Scali, Quirino Ciampi, Daniel Lichtenstein
For a cardiologist, lung ultrasound is an add-on to transthoracic echocardiography, just as lung auscultation is part of a cardiac physical examination. A cardiac 3.5- to 5.0-MHz transducer is generally suitable because the small footprint makes it ideal for scanning intercostal spaces. The image quality is often adequate, and the lung acoustic window is always patent. The cumulative increase in imaging time is <1 min for the 2 main applications targeted on pleural water (pleural effusion) and lung water (pulmonary congestion as multiple B-lines)...
November 2018: JACC. Cardiovascular Imaging
https://read.qxmd.com/read/30372119/lung-ultrasound-for-critically-ill-patients
#10
Francesco Mojoli, Bélaid Bouhemad, Silvia Mongodi, Daniel Lichtenstein
Point-of-care ultrasound is increasingly used at the bedside to integrate the clinical assessment of the critically ill; in particular, lung ultrasound greatly developed in the last decade. This review describes basic lung ultrasound signs and focuses on their applications in critical care. Lung semiotic is made both of artifacts (derived by air/tissue interface) and real images (i.e. effusions and consolidations), both providing significant information to identify the main acute respiratory disorders. Lung ultrasound signs, either alone or combined to other point-of-care ultrasound techniques, are helpful in the diagnostic approach to patients with acute respiratory failure, circulatory shock or cardiac arrest...
October 29, 2018: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/30030573/lung-ultrasound-in-a-dyspneic-patient-with-giant-bullae
#11
Daniel Lichtenstein, Gemma Rialp
No abstract text is available yet for this article.
July 20, 2018: Intensive Care Medicine
https://read.qxmd.com/read/29776972/improving-serum-calcium-test-ordering-according-to-a-decision-algorithm
#12
Daniel K Faria, Leandro U Taniguchi, Luiz A M Fonseca, Mario Ferreira-Junior, Francisco J B Aguiar, Arnaldo Lichtenstein, Nairo M Sumita, Alberto J S Duarte, Maria M Sales
AIM: To detect differences in the pattern of serum calcium tests ordering before and after the implementation of a decision algorithm. METHODS: We studied patients admitted to an internal medicine ward of a university hospital on April 2013 and April 2016. Patients were classified as critical or non-critical on the day when each test was performed. Adequacy of ordering was defined according to adherence to a decision algorithm implemented in 2014. RESULTS: Total and ionised calcium tests per patient-day of hospitalisation significantly decreased after the algorithm implementation; and duplication of tests (total and ionised calcium measured in the same blood sample) was reduced by 49%...
May 18, 2018: Journal of Clinical Pathology
https://read.qxmd.com/read/29620072/neurobehavioral-characterization-of-adult-onset-alexander-disease-a-family-study
#13
Maya L Lichtenstein, Emily Dwosh, Anupama Roy Chowdhury, Matthew J Farrer, Marna B McKenzie, Ilaria Guella, Daniel M Evans, Haakon B Nygaard, Jason R Shewchuk, Sherri Hayden, Jason J S Barton, Howard H Feldman
No abstract text is available yet for this article.
October 2017: Neurology. Clinical Practice
https://read.qxmd.com/read/29604292/improved-diet-quality-associates-with-reduction-in-liver-fat-particularly-in-individuals-with-high-genetic-risk-scores-for-nonalcoholic-fatty-liver-disease
#14
Jiantao Ma, Rachel Hennein, Chunyu Liu, Michelle T Long, Udo Hoffmann, Paul F Jacques, Alice H Lichtenstein, Frank B Hu, Daniel Levy
BACKGROUND & AIMS: Dietary modification has been recommended for treatment of nonalcoholic fatty liver disease (NAFLD), although it is not clear whether improving diet quality can prevent its development. We performed a prospective study to examine the association between diet quality change and change in liver fat. We also examined the association between genetic risk score and liver fat change in individuals with different levels of diet quality change. METHODS: Our study included 1521 participants who attended the seventh and eighth examinations (1998-2001 and 2005-2008) of the second-generation cohort or attended the first and second examinations (2002-2005 and 2008-2011) of the third-generation cohort in the Framingham Heart Study...
July 2018: Gastroenterology
https://read.qxmd.com/read/29603866/genome-wide-analysis-of-adolescent-psychotic-like-experiences-shows-genetic-overlap-with-psychiatric-disorders
#15
Oliver Pain, Frank Dudbridge, Alastair G Cardno, Daniel Freeman, Yi Lu, Sebastian Lundstrom, Paul Lichtenstein, Angelica Ronald
This study aimed to test for overlap in genetic influences between psychotic-like experience traits shown by adolescents in the community, and clinically-recognized psychiatric disorders in adulthood, specifically schizophrenia, bipolar disorder, and major depression. The full spectra of psychotic-like experience domains, both in terms of their severity and type (positive, cognitive, and negative), were assessed using self- and parent-ratings in three European community samples aged 15-19 years (Final N incl...
June 2018: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://read.qxmd.com/read/29444707/percutaneous-transhepatic-vs-endoscopic-retrograde-biliary-drainage-for-suspected-malignant-hilar-obstruction-study-protocol-for-a-randomized-controlled-trial
#16
Firas Al-Kawas, Harry Aslanian, John Baillie, Filip Banovac, Jonathan M Buscaglia, James Buxbaum, Amitabh Chak, Bradford Chong, Gregory A Coté, Peter V Draganov, Kulwinder Dua, Valerie Durkalski, B Joseph Elmunzer, Lydia D Foster, Timothy B Gardner, Brian S Geller, Priya Jamidar, Laith H Jamil, Rajesh N Keswani, Mouen A Khashab, Gabriel D Lang, Ryan Law, David Lichtenstein, Simon K Lo, Sean McCarthy, Silvio Melo, Daniel Mullady, Jose Nieto, J Bayne Selby, Vikesh K Singh, Rebecca L Spitzer, Brian Strife, Paul Tarnaksy, Jason R Taylor, Jeffrey Tokar, Andrew Y Wang, April Williams, Field Willingham, Patrick Yachimski
BACKGROUND: The optimal approach to the drainage of malignant obstruction at the liver hilum remains uncertain. We aim to compare percutaneous transhepatic biliary drainage (PTBD) to endoscopic retrograde cholangiography (ERC) as the first intervention in patients with cholestasis due to suspected malignant hilar obstruction (MHO). METHODS: The INTERCPT trial is a multi-center, comparative effectiveness, randomized, superiority trial of PTBD vs. ERC for decompression of suspected MHO...
February 14, 2018: Trials
https://read.qxmd.com/read/29258479/surgical-treatment-strategies-for-giant-inguinoscrotal-hernia-a-case-report-with-review-of-the-literature
#17
REVIEW
Julia Isabelle Staubitz, Peter Gassmann, Daniel Wilhelm Kauff, Hauke Lang
BACKGROUND: An inguinoscrotal hernia is defined as "giant" if descending below the midpoint of the inner thigh of a patient in upright position. In developed countries this is a rare entity. In the literature different surgical techniques have been reported so far to achieve a successful treatment. CASE PRESENTATION: We present the case of a 63 year-old man suffering from a giant inguinoscrotal hernia, whom we treated using a combined open transabdominal and inguinal approach following an unsuccessful laparoscopic attempt...
December 19, 2017: BMC Surgery
https://read.qxmd.com/read/29192422/executive-summary-on-the-use-of-ultrasound-in-the-critically-ill-consensus-report-from-the-3rd-course-on-acute-care-ultrasound-cacu
#18
REVIEW
Manu L N G Malbrain, Brecht De Tavernier, Sandrine Haverals, Michel Slama, Antoine Vieillard-Baron, Adrian Wong, Jan Poelaert, Xavier Monnet, Willem Stockman, Paul Elbers, Daniel Lichtenstein
Over the past decades, ultrasound (US) has gained its place in the armamentarium of monitoring tools in the intensive care unit (ICU). Critical care ultrasonography (CCUS) is the combination of general CCUS (lung and pleural, abdominal, vascular) and CC echocardiography, allowing prompt assessment and diagnosis in combination with vascular access and therapeutic intervention. This review summarises the findings, challenges lessons from the 3rd Course on Acute Care Ultrasound (CACU) held in November 2015, Antwerp, Belgium...
2017: Anaesthesiology Intensive Therapy
https://read.qxmd.com/read/29151003/lung-ultrasound-in-the-critically-ill-luci-a-translational-discipline
#19
REVIEW
Daniel A Lichtenstein, Manu L N G Malbrain
In the early days of ultrasound, it was not a translational discipline. The heart was claimed by cardiologists, with others, such as gynaecologists, urologists and vascular surgeons claiming their part while the rest was given to radiologists. Only recently, ultrasound transgressed and crossed the usual borders between the different disciplines, such as emergency and critical care medicine. The advent of portable machines in the early 1980s, allowed the critical care physician to perform bedside ultrasound, and the development of whole body critical care ultrasound (CCUS) was born...
2017: Anaesthesiology Intensive Therapy
https://read.qxmd.com/read/29129535/genetic-influence-on-eye-movements-to-complex-scenes-at-short-timescales
#20
Daniel P Kennedy, Brian M D'Onofrio, Patrick D Quinn, Sven Bölte, Paul Lichtenstein, Terje Falck-Ytter
Where one looks within their environment constrains one's visual experiences, directly affects cognitive, emotional, and social processing [1-4], influences learning opportunities [5], and ultimately shapes one's developmental path. While there is a high degree of similarity across individuals with regard to which features of a scene are fixated [6-8], large individual differences are also present, especially in disorders of development [9-13], and clarifying the origins of these differences is essential to understand the processes by which individuals develop within the complex environments in which they exist and interact...
November 20, 2017: Current Biology: CB
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