keyword
https://read.qxmd.com/read/38520736/healthy-lifestyle-is-a-protective-factor-from-moderate-and-severe-relapses-and-steroid-use-in-inflammatory-bowel-disease-a-prospective-cohort-study
#1
JOURNAL ARTICLE
Sandra García-Mateo, Samuel Jesús Martínez-Domínguez, Carla Jerusalén Gargallo-Puyuelo, Beatriz Gallego, Erika Alfambra, María Escuin, Sergio García-Mateo, Julia López, Fernando Gomollón
BACKGROUND: A healthy lifestyle, including good adherence to a Mediterranean diet (MD) and regular physical exercise, may be an important factor during the course of inflammatory bowel disease (IBD). Our aim is to determine whether adherence to MD, physical activity, and the combination of both can impact on IBD course. METHODS: This prospective cohort study includes 693 IBD outpatients who were in remission with a median follow-up time of 27 months (interquartile range 22-29 months)...
March 23, 2024: Inflammatory Bowel Diseases
https://read.qxmd.com/read/38464169/genomic-surveillance-of-malaria-parasites-in-an-indigenous-community-in-the-peruvian-amazon
#2
Luis Cabrera-Sosa, Oscar Nolasco, Johanna H Kattenberg, Carlos Fernandez-Miñope, Hugo O Valdivia, Keare Barazorda, Silvia Arévalo de Los Rios, Hugo Rodriguez-Ferrucci, Joseph M Vinetz, Anna Rosanas-Urgell, Jean-Pierre Van Geertruyden, Dionicia Gamboa, Christopher Delgado-Ratto
Hard-to-reach communities represent Peru's main challenge for malaria elimination, but information about transmission in these areas is scarce. Here, we assessed Plasmodium vivax (Pv) and P. falciparum (Pf) transmission dynamics, resistance markers, and Pf hrp 2/3 deletions in Nueva Jerusalén (NJ), a remote, indigenous community in the Peruvian Amazon with high population mobility. We collected samples from November 2019 to May 2020 by active (ACD) and passive case detection (PCD) in NJ. Parasites were identified with microscopy and PCR...
February 29, 2024: Research Square
https://read.qxmd.com/read/38445785/effectiveness-and-safety-of-a-third-line-rescue-treatment-for-acute-severe-ulcerative-colitis-refractory-to-infliximab-or-ciclosporin-reasuc-study
#3
JOURNAL ARTICLE
María José García, Sabino Riestra, Aurelien Amiot, Mette Julsgaard, Irene García de la Filia, Margalida Calafat, Mariam Aguas, Luisa de la Peña, Cristina Roig, Berta Caballol, María José Casanova, Klaudia Farkas, Trine Boysen, Luis Bujanda, Camila Cuarán, Daniela Dobru, Fotios Fousekis, Carla Jerusalén Gargallo-Puyuelo, Edoardo Savarino, Xavier Calvet, José María Huguet, Limas Kupcinskas, Julia López-Cardona, Tim Raine, Joep van Oostrom, Javier P Gisbert, María Chaparro
BACKGROUND: The advent of new therapeutic agents and the improvement of supporting care might change the management of acute severe ulcerative colitis (ASUC) and avoid colectomy. AIMS: To evaluate the colectomy-free survival and safety of a third-line treatment in patients with ASUC refractory to intravenous steroids and who failed either infliximab or ciclosporin. METHODS: Multicentre retrospective cohort study of patients with ASUC refractory to intravenous steroids who had failed infliximab or ciclosporin and received a third-line treatment during the same hospitalisation...
March 6, 2024: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/37764769/lifestyle-can-exert-a-significant-impact-on-the-development-of-metabolic-complications-and-quality-life-in-patients-with-inflammatory-bowel-disease
#4
JOURNAL ARTICLE
Sandra García-Mateo, Samuel J Martínez-Domínguez, Carla Jerusalén Gargallo-Puyuelo, María Teresa Arroyo Villarino, Viviana Laredo De La Torre, Beatriz Gallego, Erika Alfambra, Fernando Gomollón
Inflammatory bowel diseases (IBDs) are associated with an increased risk of metabolic comorbidities. There is a lack of data regarding the relationship between lifestyle and metabolic diseases in IBD patients. A cross-sectional study on consecutive IBD outpatients was conducted. Adherence to the Mediterranean diet (MD) was assessed using a 14-item questionnaire from the PREDIMED study, and physical activity was evaluated using the GODIN-Leisure score. Body composition was studied based on body mass index and waist-hip ratio (WHR), while quality of life was assessed using a nine-item short questionnaire...
September 14, 2023: Nutrients
https://read.qxmd.com/read/37089065/real-world-outcomes-of-switching-from-adalimumab-originator-to-adalimumab-biosimilar-in-patients-with-inflammatory-bowel-disease-the-ada-switch-study
#5
JOURNAL ARTICLE
María José Casanova, Óscar Nantes, Pilar Varela, Milagros Vela-González, Montserrat Rivero, Olivia Sierra-Gabarda, Sabino Riestra, Manuel Barreiro-de Acosta, María Del Mar Martín-Rodríguez, Carla Jerusalén Gargallo-Puyuelo, Cristina Reygosa, Roser Muñoz, Irene García de la Filia-Molina, Andrea Núñez-Ortiz, Lilyan Kolle, Margalida Calafat, José María Huguet, Eva Iglesias-Flores, Teresa de Jesús Martínez-Pérez, Orencio Bosch, José María Duque-Alcorta, Santiago Frago-Larramona, Manuel Van Domselaar, Víctor Manuel González-Cosano, Luis Bujanda, Saioa Rubio, Alejo Mancebo, Beatriz Castro, Santiago García-López, Ruth de Francisco, Laura Nieto-García, Viviana Laredo, Ana Gutiérrez-Casbas, Francisco Mesonero, Eduardo Leo-Carnerero, Fiorella Cañete, Lucía Ruiz, Beatriz Gros, María Del Moral-Martínez, Cristina Rodríguez, María Chaparro, Javier P Gisbert
BACKGROUND AND AIMS: Data on the outcomes after switching from adalimumab (ADA) originator to ADA biosimilar are limited. The aim was to compare the treatment persistence, clinical efficacy, and safety outcomes in inflammatory bowel disease patients who maintained ADA originator vs. those who switched to ADA biosimilar. METHODS: Patients receiving ADA originator who were in clinical remission at standard dose of ADA originator were included. Patients who maintained ADA originator formed the non-switch cohort (NSC), and those who switched to different ADA biosimilars constituted the switch cohort (SC)...
July 2023: Alimentary Pharmacology & Therapeutics
https://read.qxmd.com/read/36503054/a-standardized-method-for-genus-colletotrichum-characterization-by-isothermal-microcalorimetry-using-thermokinetic-parameters
#6
JOURNAL ARTICLE
Jerusalén Betancourt-Rodríguez, Victor Manuel Zamora-Gasga, Juan Arturo Ragazzo-Sánchez, José Alberto Narváez Zapata, Montserrat Calderón-Santoyo
A new standardized method, using isothermal microcalorimetry (IMC), was established to determine thermokinetic parameters from heat flow curves and to demonstrate the reproducibility and repeatability of the parameters of five Colletotrichum species on different days. Measurements on IMC were made at different periods and by two operators. Repeatability and reproducibility (R&R) measurement system analysis was performed on the technique used to measure the heat flow of Colletotrichum strains. The results showed that the %GageR&R was found to be within the acceptable ranges of a measurement system...
December 8, 2022: Journal of Microbiological Methods
https://read.qxmd.com/read/34400187/location-morphology-and-invasiveness-of-lateral-spreading-tumors-in-the-colorectum-differ-between-two-large-cohorts-from-an-eastern-and-western-country
#7
JOURNAL ARTICLE
Carlos Guarner-Argente, Hiroaki Ikematsu, Shozo Osera, Maria Fraile, Berta Ibañez, Carlos Berta Marra-López, Carla Jerusalén-Gargallo, Pedro A Alonso Aguirre, David Martinez-Ares, Santiago Soto, Felipe Ramos Zabala, Marco Antonio Alvarez-Gonzalez, Joaquin Rodriguez Sánchez, Fernando Múgica, Oscar Nogales Rincon, Alberto Herreros de Tejada, Eduardo Redondo-Cerezo, Juan Martínez-Cara, Leopoldo López-Rosés, Manuel Rodriguez-Tellez, Orlando Garcia-Bosch, Joaquín de la Peña, María Pellisé, Liseth Rivero-Sanchez, Esteve Saperas, Francisco Pérez-Roldán, Bartolome Lopez Viedma, Jesús M González-Santiago, Alberto Álvarez Delgado, Carol Cobian, Remedios Pardeiro, Eduardo Valdivielso Cortázar, Juan Colan-Hernandez, Jordi Gordillo, Kazuhiro Kaneko, Eduardo Albéniz
BACKGROUND AND STUDY AIMS: Data from Japanese series show that surface morphology of laterally spreading tumors (LST) in the colon identifies lesions with different incidence and pattern of submucosal invasion. Such data from western countries are scarce. We compared clinical and histological features of LST in a western country and an eastern country, with special interest on mucosal invasiveness of LST, and investigated the effect of clinical factors on invasiveness in both countries...
August 13, 2021: Gastroenterología y Hepatología
https://read.qxmd.com/read/34302036/changes-in-the-use-patterns-of-bdmards-in-patients-with-rheumatic-diseases-over-the-past-13-years
#8
JOURNAL ARTICLE
Carlos Sánchez-Piedra, Diana Sueiro-Delgado, Javier García-González, Inmaculada Ros-Vilamajo, Agueda Prior-Español, Manuel José Moreno-Ramos, Blanca Garcia-Magallon, Jerusalen Calvo-Gutiérrez, Yanira Perez-Vera, Raquel Martín-Domenech, Dolores Ruiz-Montesino, Paloma Vela-Casasempere, Lorena Expósito, Fernando Sánchez-Alonso, Enrique González-Davila, Federico Díaz-González
The better understanding of the safety of biologic DMARDs (bDMARDs), as well as the emergence of new bDMARDs against different therapeutic targets and biosimilars have likely influenced the use patterns of these compounds over time. The aim of this study is to assess changes in demographic characteristics, disease activity and treatment patterns in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA), or ankylosing spondylitis (AS) who started a first- or second-line biologic between 2007 and mid-2020...
July 23, 2021: Scientific Reports
https://read.qxmd.com/read/34023473/impact-of-the-lockdown-period-due-to-the-covid-19-pandemic-in-patients-with-inflammatory-bowel-disease
#9
JOURNAL ARTICLE
Engy Refaie, Sandra García Mateo, Samuel Jesús Martínez Domínguez, Carla Jerusalén Gargallo-Puyuelo, Laura Lario Quilez, Patricia Carrera-Lasfuentes, María Teresa Arroyo Villarino, Fernando Gomollón García
INTRODUCTION: The lockdown period due to the coronavirus disease 2019 (COVID-19) in Spain probably had a significant emotional impact on chronic patients and hence on those who are suffering from inflammatory bowel disease (IBD) due to their high risk of emotional disorders. The aim of this study was to learn how COVID-19 influenced patients suffering from IBD during the quarantine period, focusing in particular on psychological distress through the Perceived Stress Scale-10 (PSS-10) and also the impact of the pandemic on therapeutic adherence using the Visual Analogue Scale (VAS)...
May 20, 2021: Gastroenterología y Hepatología
https://read.qxmd.com/read/32910753/disease-modifying-antirheumatic-drug-prescription-patterns-in-adult-rheumatoid-arthritis-patients-in-routine-clinical-practice-in-spain
#10
JOURNAL ARTICLE
Blanca Hernández Cruz, Inmaculada Ureña Garnica, Ricardo Sánchez Parera, Esteban Rubio Romero, Jerusalén Calvo Gutiérrez, Antonio García Sánchez, Carlos Rodríguez Escalera, Federico Navarro Sarabia
OBJECTIVE: To describe disease-modifying antirheumatic drug (DMARD) patterns in routine clinical practice in adult rheumatoid arthritis (RA) patients and to ascertain the reasons for methotrexate (MTX) discontinuation. METHODS: A cross-sectional observational study was conducted from March to October 2014 at the Rheumatology Units of seven hospitals in Spain. In a single visit, the treating rheumatologist completed an online case report form. This report contained sociodemographic and RA variables...
September 3, 2020: European Journal of Rheumatology
https://read.qxmd.com/read/31655045/clinical-validation-of-risk-scoring-systems-to-predict-risk-of-delayed-bleeding-after-emr-of-large-colorectal-lesions
#11
JOURNAL ARTICLE
Eduardo Albéniz, Antonio Zebenzuy Gimeno-García, María Fraile, Berta Ibáñez, Carlos Guarner-Argente, Pedro Alonso-Aguirre, Marco Antonio Álvarez, Carla Jerusalén Gargallo, María Pellisé, Felipe Ramos Zabala, Alberto Herreros de Tejada, Óscar Nogales, David Martínez-Ares, Fernando Múgica, Joaquín de la Peña, Jorge Espinós, Alain Huerta, Alberto Álvarez, Jesús M Gonzalez-Santiago, Francisco Navajas, Juan Gabriel Martínez-Cara, Eduardo Redondo-Cerezo, Josep Merlo Mas, Fernando Sábado, Liseth Rivero, Esteban Saperas, Santiago Soto, Joaquín Rodríguez-Sánchez, Leopoldo López-Roses, Manuel Rodríguez-Téllez, María Rullán Iriarte, Alfonso Elosua González, Remedios Pardeiro, Eduardo Valdivielso Cortázar, Mar Concepción-Martín, Patricia Huelin Álvarez, Juan Colán Hernández, Julyssa Cobian, José Santiago, Alejandra Jiménez, David Remedios, Bartolomé López-Viedma, Orlando García, Felipe Martínez-Alcalá, Francisco Pérez-Roldán, Jorge Carbó, Mónica Enguita
BACKGROUND AND AIMS: The Endoscopic Resection Group of the Spanish Society of Endoscopy (GSEED-RE) model and the Australian Colonic Endoscopic Resection (ACER) model were proposed to predict delayed bleeding (DB) after EMR of large superficial colorectal lesions, but neither has been validated. We validated and updated these models. METHODS: A multicenter cohort study was performed in patients with nonpedunculated lesions ≥20 mm removed by EMR. We assessed the discrimination and calibration of the GSEED-RE and ACER models...
April 2020: Gastrointestinal Endoscopy
https://read.qxmd.com/read/29421912/clinical-guidelines-for-endoscopic-mucosal-resection-of-non-pedunculated-colorectal-lesions
#12
REVIEW
Eduardo Albéniz, María Pellisé, Antonio Z Gimeno-García, Alfredo José Lucendo, Pedro A Alonso-Aguirre, Alberto Herreros de Tejada, Marco Antonio Álvarez, María Fraile, Maite Herráiz Bayod, Leopoldo López Rosés, David Martínez Ares, Akiko Ono, Adolfo Parra Blanco, Eduardo Redondo, Andrés Sánchez-Yagüe, Santiago Soto, José Díaz-Tasende, Marta Montes Díaz, Manuel Rodríguez-Téllez, Orlando García, Alba Zuñiga Ripa, Marta Hernández Conde, Fernando Alberca de Las Parras, Carla Jerusalén Gargallo, Esteban Saperas, Miguel Muñoz Navas, Javier Gordillo, Felipe Ramos Zabala, José Manuel Echevarría, Marco Bustamante, Mariano González-Haba, Ferrán González-Huix, Begoña González-Suárez, Juan José Vila Costas, Carlos Guarner Argente, Fernando Múgica, Julyssa Cobián, Joaquín Rodríguez Sánchez, Bartolomé López Viedma, Noel Pin, José Carlos Marín Gabriel, Óscar Nogales, Joaquín de la Peña, Francisco Javier Navajas León, Helena León Brito, David Remedios, José Miguel Esteban, David Barquero, Juan Gabriel Martínez Cara, Felipe Martínez Alcalá, Ignacio Fernández-Urién, Eduardo Valdivielso
This document summarizes the contents of the Clinical Guidelines for the Endoscopic Mucosal Resection of Non-Pedunculated Colorectal Lesions that was developed by the working group of the Spanish Society of Digestive Endoscopy (GSEED of Endoscopic Resection). This document presents recommendations for the endoscopic management of superficial colorectal neoplastic lesions.
March 2018: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/27033428/a-scoring-system-to-determine-risk-of-delayed-bleeding-after-endoscopic-mucosal-resection-of-large-colorectal-lesions
#13
MULTICENTER STUDY
Eduardo Albéniz, María Fraile, Berta Ibáñez, Pedro Alonso-Aguirre, David Martínez-Ares, Santiago Soto, Carla Jerusalén Gargallo, Felipe Ramos Zabala, Marco Antonio Álvarez, Joaquín Rodríguez-Sánchez, Fernando Múgica, Óscar Nogales, Alberto Herreros de Tejada, Eduardo Redondo, Noel Pin, Helena León-Brito, Remedios Pardeiro, Leopoldo López-Roses, Manuel Rodríguez-Téllez, Alejandra Jiménez, Felipe Martínez-Alcalá, Orlando García, Joaquín de la Peña, Akiko Ono, Fernando Alberca de Las Parras, María Pellisé, Liseth Rivero, Esteban Saperas, Francisco Pérez-Roldán, Antonio Pueyo Royo, Javier Eguaras Ros, Alba Zúñiga Ripa, Mar Concepción-Martín, Patricia Huelin-Álvarez, Juan Colán-Hernández, Joaquín Cubiella, David Remedios, Xavier Bessa I Caserras, Bartolomé López-Viedma, Julyssa Cobian, Mariano González-Haba, José Santiago, Juan Gabriel Martínez-Cara, Eduardo Valdivielso, Carlos Guarner-Argente
BACKGROUND & AIMS: After endoscopic mucosal resection (EMR) of colorectal lesions, delayed bleeding is the most common serious complication, but there are no guidelines for its prevention. We aimed to identify risk factors associated with delayed bleeding that required medical attention after discharge until day 15 and develop a scoring system to identify patients at risk. METHODS: We performed a prospective study of 1214 consecutive patients with nonpedunculated colorectal lesions 20 mm or larger treated by EMR (n = 1255) at 23 hospitals in Spain, from February 2013 through February 2015...
August 2016: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/25071338/interaction-between-helicobacter-pylori-infection-nonsteroidal-anti-inflammatory-drugs-and-or-low-dose-aspirin-use-old-question-new-insights
#14
REVIEW
Carlos Sostres, Carla Jerusalen Gargallo, Angel Lanas
Previous reports clearly demonstrated that Helicobacter pylori (H. pylori) infection, nonsteroidal anti-inflammatory drugs (NSAID) or low dose aspirin (ASA) use significantly and independently increased the risk for the development of peptic ulcer disease. Today, the presence of H. pylori infection associated with low dose ASA and/or NSAID use in the same patient is becoming more frequent and therefore the potential interaction between these factors and the consequences of it has important implications. Whether NSAID intake in the presence of H...
July 28, 2014: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/24605250/aspirin-cyclooxygenase-inhibition-and-colorectal-cancer
#15
REVIEW
Carlos Sostres, Carla Jerusalen Gargallo, Angel Lanas
Colorectal cancer (CRC) is the third most common type of cancer worldwide. Screening measures are far from adequate and not widely available in resource-poor settings. Primary prevention strategies therefore remain necessary to reduce the risk of developing CRC. Increasing evidence from epidemiological studies, randomized clinical trials and basic science supports the effectiveness of aspirin, as well as other non-steroidal anti-inflammatory drugs, for chemoprevention of several types of cancer, including CRC...
February 6, 2014: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://read.qxmd.com/read/23474378/different-clinical-expression-of-patients-with-ankylosing-spondylitis-according-to-gender-in-relation-to-time-since-onset-of-disease-data-from-regisponser
#16
COMPARATIVE STUDY
Rafaela Ortega Castro, Pilar Font Ugalde, M Carmen Castro Villegas, Jerusalén Calvo Gutiérrez, Elisa Muñoz Gomariz, Pedro Zarco Montejo, Raquel Almodóvar, Juan Mulero Mendoza, Juan Carlos Torre-Alonso, Jordi Gratacós Masmitjá, Xavier Juanola Roura, Rafael Ariza Ariza, Pilar Fernández Dapica, Luis Francisco Linares Ferrando, M Elia Brito Brito, Eduardo Cuende Quintana, Carlos Vázquez Galeano, Manuel José Moreno Ramos, Eugenio Giménez Úbeda, José Carlos Rodríguez Lozano, Manuel Fernández Prada, Rubén Queiro Silva, Estefanía Moreno Ruzafa, Enrique Júdez Navarro, Antonio Juan Más, Cristina Medrano Le Quement, Enrique Ornilla, Carlos Montilla Morales, Manuel Pujol Busquets, Teresa Clavaguera Poch, M Cruz Fernández-Espartero, Loreto Carmona Ortell, Eduardo Collantes Estévez
OBJECTIVE: To describe the differential characteristics by gender and time since disease onset in patients diagnosed with ankylosing spondylitis (AS) attending the Spanish rheumatology clinics, including those on the "Spanish Registry of spondyloarthritis" (REGISPONSER), as well as the diagnostic and therapeutic implications that this entails. PATIENTS AND METHODS: This is a transversal and observational study of 1514 patients with AS selected from 2367 spondyloarthritis cases included in REGISPONSER...
July 2013: Reumatología Clinica
https://read.qxmd.com/read/20878538/glucose-free-fructose-production-from-jerusalem-artichoke-using-a-recombinant-inulinase-secreting-saccharomyces-cerevisiae-strain
#17
JOURNAL ARTICLE
Jing Yu, Jiaxi Jiang, Wangming Ji, Yuyang Li, Jianping Liu
PURPOSE OF WORK: Using inulin (polyfructose) obtained from Jerusalen artichokes, we have produced fructose free of residual glucose using a recombinant inulinase-secreting strain of Saccharomyces cerevisiae in a one-step fermentation of Jerusalem artichoke tubers. For producing fructose from inulin, a recombinant inulinase-producing Saccharomyce cerevisiae strain was constructed with a deficiency in fructose uptake by disruption of two hexokinase genes hxk1 and hxk2. The inulinase gene introduced into S. cerevisiae was cloned from Kluyveromyces cicerisporus...
January 2011: Biotechnology Letters
https://read.qxmd.com/read/16100143/prolonged-intubation-rates-after-coronary-artery-bypass-surgery-and-icu-risk-stratification-score
#18
JOURNAL ARTICLE
Nicolás Serrano, Carolina García, Jerusalén Villegas, Samantha Huidobro, Christophe Charles Henry, Ruth Santacreu, María Luisa Mora
OBJECTIVE: To determine prolonged intubation rates among patients undergoing coronary artery bypass graft (CABG) surgery, and to evaluate the ability of the Intensive Care Unit Risk Stratification Score (ICURSS) model to predict these events. DESIGN: Prospective observational study. SETTING: A 24-bed ICU in a tertiary referral university hospital. PATIENTS: Five hundred sixty-nine patients undergoing CABG surgery. INTERVENTIONS: Variables of the ICURSS model were recorded at ICU admission...
August 2005: Chest
https://read.qxmd.com/read/15160239/catheter-related-infection-in-critically-ill-patients
#19
JOURNAL ARTICLE
Leonardo Lorente, Jerusalen Villegas, María M Martín, Alejandro Jiménez, María L Mora
OBJECTIVE: To describe the incidence of the catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) of central venous catheters (CVCs) and arterial catheters (ACs). DESIGN: Prospective, observational study. SETTING: A 24-bed medical-surgical intensive care unit of a 650-bed university hospital. PATIENTS: We included 988 consecutive patients admitted to the ICU during 18 months. MEASUREMENTS: The incidence density of CRLI and CRBSI, per 1000 catheter-days, of CVC and AC...
August 2004: Intensive Care Medicine
https://read.qxmd.com/read/14247127/-erythro-and-lymphopoiesis-in-the-mouse-spleen-in-plasmodium-berghei-infection
#20
JOURNAL ARTICLE
C JERUSALEN, W KRETSCHMAR
No abstract text is available yet for this article.
1964: Verhandlungen der Anatomischen Gesellschaft
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