keyword
https://read.qxmd.com/read/38526927/definition-frequency-and-risk-factors-for-intra-operative-spinal-cord-injury-a-knowledge-synthesis
#21
JOURNAL ARTICLE
Michael G Fehlings, Ayesha Quddusi, Andrea C Skelly, Erika D Brodt, Ali Moghaddamjou, Anahita Malvea, Nader Hejrati, Nisaharan Srikandarajah, Mohammed Ali Alvi, Shay Stabler-Morris, Joseph R Dettori, Lindsay A Tetreault, Nathan Evaniew, Brian K Kwon
STUDY DESIGN: Mixed-methods approach. OBJECTIVES: Intra-operative spinal cord injury (ISCI) is a devastating complication of spinal surgery. Presently, a uniform definition for ISCI does not exist. Consequently, the reported frequency of ISCI and important risk factors vary in the existing literature. To address these gaps in knowledge, a mixed-methods knowledge synthesis was undertaken. METHODS: A scoping review was conducted to review the definitions used for ISCI and to ascertain the frequency of ISCI...
March 2024: Global Spine Journal
https://read.qxmd.com/read/38523334/effect-of-standardized-bundle-care-and-bundle-compliance-on-reducing-surgical-site-infections-a-pragmatic-retrospective-cohort-study
#22
JOURNAL ARTICLE
Yu-San Chien, Hsiang-Ting Chen, Hsiu-Tzy Chiang, Tz-Shin Luo, Hung-I Yeh, Jin-Cherng Sheu, Jiun-Yi Li
BACKGROUND Care bundles for infection control consist of a set of evidence-based measures to prevent infections. This retrospective study aimed to compare surgical site infections (SSIs) from a single hospital surveillance system between 2017 and 2020, before and after implementing a standardized care bundle across specialties in 2019. It also aimed to assess whether bundle compliance affects the rate of SSIs. MATERIAL AND METHODS A care bundle consisting of 4 components (peri-operative antibiotics use, peri-operative glycemic control, pre-operative skin preparation, and maintaining intra-operative body temperature) was launched in 2019...
March 25, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38513090/mid-infrared-trace-detection-with-parts-per-quadrillion-quantitation-accuracy-expanding-frontiers-of-radiocarbon-sensing
#23
JOURNAL ARTICLE
Jun Jiang, A Daniel McCartt
Detection sensitivity is a critical characteristic to consider during selection of spectroscopic techniques. However, high sensitivity alone is insufficient for spectroscopic measurements in spectrally congested regions. Two-color cavity ringdown spectroscopy (2C-CRDS), based on intra-cavity pump-probe detection, simultaneously achieves high detection sensitivity and selectivity. This combination enables mid-infrared detection of radiocarbon dioxide ([Formula: see text]CO[Formula: see text]) molecules in room-temperature CO[Formula: see text] samples, with 1...
April 9, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38512418/evaluation-of-management-of-ct-scan-proved-solid-organ-injury-in-blunt-injury-abdomen-a-prospective-study
#24
JOURNAL ARTICLE
Sourodip Mukharjee, Dinesh B V, Bharath S V
BACKGROUND: Trauma especially road traffic injury is one of the major health-related issues throughout the world, especially in developing countries like India (Mattox 2022). Solid organ injury is the most common cause of morbidity and mortality in patients with blunt abdominal trauma. The non-operative management (NOM) is being consistently followed for hemodynamically stable patients with respect to solid organ injuries. This study aims to provide an evidence base for management modalities of solid organ injuries in blunt abdominal trauma...
March 21, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38503707/-determination-of-nine-aromatic-amines-in-water-by-cloud-point-extraction-gas-chromatography-mass-spectrometry
#25
JOURNAL ARTICLE
Chao Yang, Jing-Long Liu, Xiao-Jian Xu, Li-Juan Wu, Ming-Ming Yin, Wei Dai, Qian Han
Aromatic amines are a class of compounds bearing amino groups on their benzene rings; these compounds are important raw materials for the industrial production of rubber chemicals, pesticides, dyes, pharmaceuticals, photosensitive chemicals, and agricultural chemicals. Research has revealed that some aromatic amines teratogenetic, carcinogenic, and mutagenic properties. Given the high toxicity and potential harm caused by aromatic amines, monitoring their levels in water sources is critical. Aromatic amines are among the 14 strategic environmental pollutants blacklisted in China, and assessing their exposure levels is essential for protecting human health and the environment...
March 8, 2024: Se Pu, Chinese Journal of Chromatography
https://read.qxmd.com/read/38502358/high-intra-patient-variability-of-tacrolimus-within-post-operative-1%C3%A2-month-predicted-worse-1-year-outcomes-in-pediatric-liver-transplant-recipients
#26
JOURNAL ARTICLE
Fang Chen, June-Kong Yong, Chuan Shen, Tao Zhou, Mingxuan Feng, Ping Wan, Yi Luo, Houwen Lin, Yongbing Qian, Qiang Xia
BACKGROUND: The pharmacokinetics of tacrolimus (TAC) show high intra-patient variability (IPV), which is associated with poor long-term outcomes following adult liver transplantation (LT). However, this relationship remains to be confirmed in pediatric liver transplant (PLT) recipients. The present study aimed to investigate the association between TAC IPV and grafts or patient outcomes after pediatric liver transplantion. METHODS: This retrospective study included 848 PLT recipients (including infants) between January, 2016, and June, 2021...
March 19, 2024: European Journal of Clinical Pharmacology
https://read.qxmd.com/read/38499146/usefulness-of-motor-evoked-potential-measurement-and-analysis-of-risk-factors-for-spinal-cord-ischaemia-from-300-cases-of-thoracic-endovascular-aortic-repair
#27
JOURNAL ARTICLE
Mizuki Ando, Yuya Kise, Yukio Kuniyoshi, Shotaro Higa, Takaaki Nagano, Kojiro Furukawa
OBJECTIVE: This study investigated the usefulness of motor evoked potentials (MEPs) for intra-operative monitoring to detect the risk of spinal cord ischaemia (SCI) during thoracic endovascular aortic repair (TEVAR). Risk factors for SCI in TEVAR were also analysed. METHODS: Among 330 TEVARs performed from February 2009 to October 2018, 300 patients underwent intra-operative MEP monitoring. SCI risk groups were extracted based on MEP amplitude changes using a cutoff value of 50%...
March 16, 2024: European Journal of Vascular and Endovascular Surgery
https://read.qxmd.com/read/38489990/machine-learning-on-cardiotocography-data-to-classify-fetal-outcomes-a-scoping-review
#28
JOURNAL ARTICLE
Farah Francis, Saturnino Luz, Honghan Wu, Sarah J Stock, Rosemary Townsend
INTRODUCTION: Uterine contractions during labour constrict maternal blood flow and oxygen delivery to the developing baby, causing transient hypoxia. While most babies are physiologically adapted to withstand such intrapartum hypoxia, those exposed to severe hypoxia or with poor physiological reserves may experience neurological injury or death during labour. Cardiotocography (CTG) monitoring was developed to identify babies at risk of hypoxia by detecting changes in fetal heart rate (FHR) patterns...
April 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38487721/capacity-building-for-pediatric-neuro-oncology-in-pakistan-a-project-by-my-child-matters-program-of-foundation-s
#29
JOURNAL ARTICLE
Naureen Mushtaq, Bilal Mazhar Qureshi, Gohar Javed, Nabeel Ashfaque Sheikh, Saqib Kamran Bakhshi, Altaf Ali Laghari, Syed Ather Enam, Shayan Sirat Maheen Anwar, Kiran Hilal, Arsalan Kabir, Alia Ahmad, Amber Goraya, Anum Salman Mistry, Aqeela Rashid, Ata Ur Rehman Maaz, Muhammad Atif Munawar, Atiq Ahmed Khan, Farrah Bashir, Hina Hashmi, Kamran Saeed, Kumail Khandwala, Lal Rehman, Michael C Dewan, Muhammad Saghir Khan, Muneeb Uddin Karim, Najma Shaheen, Nida Zia, Nuzhat Yasmeen, Raheela Mahmood, Riaz Ahmed Raja Memon, Salman Kirmani, Shahzadi Resham, Shazia Kadri, Shazia Riaz, Syed Ahmer Hamid, Tariq Ghafoor, Uzma Imam, Yaseen Rauf Mushtaq, Zulfiqar Ali Rana, Eric Bouffet, Khurram Minhas
INTRODUCTION: Initiated in June 2019, this collaborative effort involved 15 public and private sector hospitals in Pakistan. The primary objective was to enhance the capacity for pediatric neuro-oncology (PNO) care, supported by a My Child Matters/Foundation S grant. METHODS: We aimed to establish and operate Multidisciplinary Tumor Boards (MTBs) on a national scale, covering 76% of the population (185.7 million people). In response to the COVID-19 pandemic, MTBs transitioned to videoconferencing...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38476554/comparison-of-the-effects-of-dexmedetomidine-and-nitroglycerin-on-cerebral-oxygen-saturation-using-near-infrared-spectroscopy-in-patients-undergoing-controlled-hypotensive-anaesthesia-a-randomised-controlled-non-inferiority-trial
#30
JOURNAL ARTICLE
J Koteswara Rao, Swati Chhabra, Sadik Mohammed, Pradeep K Bhatia, Shilpa Goyal, Rakesh Kumar
BACKGROUND AND AIMS: There is limited literature wherein the hypotensive drugs have been compared to know the cerebral effects by monitoring regional cerebral oxygen saturation (rScO2 ). This study aimed to compare the effects of dexmedetomidine and nitroglycerin on rScO2 during controlled hypotensive anaesthesia using near-infrared spectroscopy (NIRS). The primary objective was to evaluate the non-inferiority of dexmedetomidine versus nitroglycerin in the occurrence of cerebral desaturation events (CDEs) during hypotensive anaesthesia...
March 2024: Indian Journal of Anaesthesia
https://read.qxmd.com/read/38475832/prehospital-invasive-arterial-blood-pressure-monitoring-in-critically-ill-patients-attended-by-a-uk-helicopter-emergency-medical-service-a-retrospective-observational-review-of-practice
#31
JOURNAL ARTICLE
Emma D Butterfield, James Price, Marco Bonsano, Kate Lachowycz, Zachary Starr, Christopher Edmunds, Jon Barratt, Rob Major, Paul Rees, Ed B G Barnard
BACKGROUND: Accurate haemodynamic monitoring in the prehospital setting is essential. Non-invasive blood pressure measurement is susceptible to vibration and motion artefact, especially at extremes of hypotension and hypertension: invasive arterial blood pressure (IABP) monitoring is a potential solution. This study describes the largest series to date of cases of IABP monitoring being initiated prehospital. METHODS: This retrospective observational study was conducted at East Anglian Air Ambulance (EAAA), a UK helicopter emergency medical service (HEMS)...
March 12, 2024: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://read.qxmd.com/read/38468391/feasibility-of-proton-dosimetry-overriding-planning-ct-with-daily-cbct-elaborated-through-generative-artificial-intelligence-tools
#32
JOURNAL ARTICLE
Matteo Rossi, Gabriele Belotti, Luca Mainardi, Guido Baroni, Pietro Cerveri
Radiotherapy commonly utilizes cone beam computed tomography (CBCT) for patient positioning and treatment monitoring. CBCT is deemed to be secure for patients, making it suitable for the delivery of fractional doses. However, limitations such as a narrow field of view, beam hardening, scattered radiation artifacts, and variability in pixel intensity hinder the direct use of raw CBCT for dose recalculation during treatment. To address this issue, reliable correction techniques are necessary to remove artifacts and remap pixel intensity into Hounsfield Units (HU) values...
December 2024: Computer Assisted Surgery (Abingdon, England)
https://read.qxmd.com/read/38441871/aborted-ais-spinal-fusion-due-to-persistent-loss-of-ionm-which-patients-are-at-greatest-risk
#33
JOURNAL ARTICLE
Connor Zale, Evan Fene, Claire Bonnyman, Lydia Klinkerman, Amy L McIntosh
PURPOSE: Determine peri-operative risk factors predictive for prematurely stopping surgery prior to completion of deformity correction due to intra-operative neuromonitoring changes. METHODS: A single institution retrospective review of adolescent idiopathic scoliosis (AIS) patients that underwent spinal fusion for curves greater than 70°. Cases aborted due to persistent loss of IONM were compared to completed cases. Demographic, radiographic, neurologic, and surgical information was reviewed...
March 5, 2024: Spine Deformity
https://read.qxmd.com/read/38436898/optimal-bispectral-index-exists-in-healthy-patients-undergoing-general-anesthesia-a-validation-study
#34
JOURNAL ARTICLE
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kangyun Park, Kevin Y Stein, Neil Berrington, Perry Dhaliwal, Frederick A Zeiler
PURPOSE: Continuous cerebrovascular reactivity monitoring in both neurocritical and intra-operative care has gained extensive interest in recent years, as it has documented associations with long-term outcomes (in neurocritical care populations) and cognitive outcomes (in operative cohorts). This has sparked further interest into the exploration and evaluation of methods to achieve an optimal cerebrovascular reactivity measure, where the individual patient is exposed to the lowest insult burden of impaired cerebrovascular reactivity...
March 4, 2024: Journal of Clinical Monitoring and Computing
https://read.qxmd.com/read/38412513/bioavailability-assessment-of-a-brompheniramine-taste-masked-pediatric-formulation-in-a-juvenile-porcine-model
#35
JOURNAL ARTICLE
Jiang Wang, Diaa Shakleya, George Giacoia, Ziyuar Rahman, Mansoor A Khan, Patrick J Faustino
A brompheniramine taste-masked pediatric formulation was developed as part of the National Institutes of Health Pediatric Formulation Initiative to help address low patient compliance caused by the bitter taste of many adult formulations. To confirm that the taste-masked formulation can provide a similar pharmacological effect to the previous marketed adult formulations, a juvenile porcine model was used to screen the model pediatric formulation to compare the bioavailability between the marketed brompheniramine maleate and the taste-masked maleate/tannate formulation...
February 27, 2024: Biomedical Chromatography: BMC
https://read.qxmd.com/read/38368505/vertical-relationship-ratio-vrr-a-high-reliability-and-accuracy-radiographic-measurement-for-basilar-invagination-in%C3%A2-rheumatoid-arthritis
#36
JOURNAL ARTICLE
Monchai Ruangchainikom, Ekkapoj Korwutthikulrangsri, Apisit Rattanatanasarn, Ishthayapong Kanjanakeereewong, Win Boonsirikamchai, Panlop Tirawanish, Surin Thanapipatsiri, Werasak Sutipornpalangkul
BACKGROUND Previous radiographic measurements for diagnosis of a basilar invagination or impression (BI) in rheumatoid arthritis (RA) were used as reference values based on anatomical reference distances. Due to the obscured anatomical landmarks, our group proposed a new radiographic measurement based on anatomic ratios to identify BI. MATERIAL AND METHODS The vertical relationship ratio (VRR) was developed and evaluated. The VRR is the relationship between the distance obtained with the modified Ranawat method and the C3 vertebral body height...
February 18, 2024: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://read.qxmd.com/read/38359643/a-universal-multi-source-domain-adaptation-method-with-unsupervised-clustering-for-mechanical-fault-diagnosis-under-incomplete-data
#37
JOURNAL ARTICLE
Jinghui Tian, Dongying Han, Hamid Reza Karimi, Yu Zhang, Peiming Shi
Recently, due to the difficulty of collecting condition data covering all mechanical fault types in industrial scenarios, the fault diagnosis problem under incomplete data is receiving increasing attention where no target prior information can be available. The existing open-set or universal domain adaptation (DA) diagnosis methods typically treat private fault samples in the target as a generalized "unknown" fault class, neglecting their inherent structure. This oversight can lead to confusion in latent feature space representations and difficulties in separating unknown samples...
February 8, 2024: Neural Networks: the Official Journal of the International Neural Network Society
https://read.qxmd.com/read/38352940/enhancing-organizational-processes-for-service-innovation-strategic-organizational-counseling-and-organizational-network-analysis
#38
JOURNAL ARTICLE
Silvia Marocco, Mara Marini, Alessandra Talamo
Previous studies have primarily focused on product innovation, overlooking the examination of organizational processes. This limited perspective poses a theoretical and practical gap as it primarily considers the external aspects of innovation. On the contrary, organizational processes play a crucial role in improving and creating internal operations necessary for product/service innovation success. To this aim, this paper presents a novel approach to enhancing service innovation within complex organizations by integrating Strategic Organizational Counseling (SOC) and Organizational Network Analysis (ONA) methodologies...
2024: Frontiers in Research Metrics and Analytics
https://read.qxmd.com/read/38345219/reduction-of-urinary-tract-infection-in-pediatric-surgical-patients-using-nsqip-p-and-quality-improvement-methodology
#39
JOURNAL ARTICLE
Kyla A Clasie, Aniruddh V Deshpande, Andrew Ja Holland, Ashish V Jiwane, Vanessa G Da Silva, Fiona A Filtness, Margaret M Allen, Grahame Hh Smith
BACKGROUND: Hospital acquired urinary tract infections (UTIs) have a detrimental effect on patients, families and hospital resources. The Sydney Children's Hospital Network (SCHN) participates in the National Surgical Quality Improvement Program - Pediatric (NSQIP-P) to monitor post operative complications. NSQIP-P data revealed that the median UTI rate at SCHN was 1.75% in 2019, 3.5 times higher than the NSQIP-P target rate of 0.5%. Over three quarters of the NSQIP-P identified UTI cases also had a urinary catheterization performed intra-operatively...
February 12, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38333301/clinical-characteristics-and-anaesthetic-management-of-severe-scoliosis-patients-with-spinal-muscular-atrophy-case-series
#40
JOURNAL ARTICLE
Lai Wang, Yi Du, Na Huang, Na Yin, Junming Du, Junlin Yang, Lai Jiang, Yanfei Mao
INTRODUCTION AND IMPORTANCE: There is no expert consensus or guidance on perioperative anaesthesia management for spinal surgery of spinal muscular atrophy (SMA) patients with severe scoliosis (Cobb≧90°). We provide a comprehensive summary of the perioperative characteristics observed in patients with SMA and propose an optimized perioperative management strategy for anaesthesia. METHODS: This study is a retrospective single-centre research. Twenty-six SMA patients with severe scoliosis underwent posterior spinal fusion surgery from September 2019 to September 2022 were enroled...
February 2024: Annals of Medicine and Surgery
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