Julia Herzig-Nichtweiß, Farid Salih, Sascha Berning, Michael P Malter, Johann O Pelz, Piergiorgio Lochner, Matthias Wittstock, Albrecht Günther, Angelika Alonso, Hannah Fuhrer, Silvia Schönenberger, Martina Petersen, Felix Kohle, Annekatrin Müller, Alexander Gawlitza, Waldemar Gubarev, Martin Holtkamp, Bernd J Vorderwülbecke
BACKGROUND: Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked seizure relapse with respect to the use of antiseizure medications. It was hypothesized that after a first acute symptomatic seizure of structural etiology, the cumulative 12-month risk of unprovoked seizure relapse is ≤ 25%...
September 15, 2023: Annals of Intensive Care