Francesca Benedetti, Giovannino Silvestri, Frank Denaro, Giovanni Finesso, Rafael Contreras-Galindo, Arshi Munawwar, Sumiko Williams, Harry Davis, Joseph Bryant, Yin Wang, Enrico Radaelli, Chozha V Rathinam, Robert C Gallo, Davide Zella
Well-controlled repair mechanisms are involved in the maintenance of genomic stability, and their failure can precipitate DNA abnormalities and elevate tumor risk. In addition, the tumor microenvironment, enriched with factors inducing oxidative stress and affecting cell cycle checkpoints, intensifies DNA damage when repair pathways falter. Recent research has unveiled associations between certain bacteria, including Mycoplasmas , and various cancers, and the causative mechanism(s) are under active investigation...
March 5, 2024: Proceedings of the National Academy of Sciences of the United States of America