Dupytren’s

STUDY DESIGN: Longitudinal Case Series. INTRODUCTION: Dupytren's contracture is thought to result in digital impairments and performance disabilities. No study to date has focused on how patients with Dupuytren's contracture experience limitations in daily activities and the results after surgery. PURPOSE OF THE STUDY: Describe which activities patients with Dupuytren's contracture defined as the most disabling, how they rated their activity limitations and determine the relationship between activity limitations and digital extension before and three months after surgery and postoperative hand therapy...

No abstract text is available yet for this article.

Currently, surgical intervention is the only efficacious treatment for Peyronie's disease (PD), a fibromatosis of the tunica albuginea of the penis. Therapies based on the molecular pathways for this disease could provide alternatives to surgical treatment but only recently has the pathophysiology of the Peyronie's disease plaque been investigated at the molecular level. In this review, we examine the current knowledge of gene expression in the PD plaque and the relationship of PD with other fibrotic conditions such as Dupytren's disease...

OBJECTIVE: Acquisition of clinical skills, after completing a course in the basic sciences, is an essential aspect of undergraduate training in any medical school. These skills are usually divided into 3 broad categories: namely, history taking, physical examination and selection of the appropriate laboratory investigations. At the end of the clerkship, the students' clinical skills have to be assessed. The main objective was to describe the performance profile of a group of medical students while examing a distended abdomen in the United Arab Emirates...

Limited finger joint mobility, Dupuytren's contracture, and the complications of diabetes were assessed in 233 Type 2 diabetic patients. Limited joint mobility was present in 34% and Dupytren's contracture in 26%. The prevalence of limited joint mobility and Dupuytren's contracture increased with duration of diabetes and with age. Logistic regression analysis showed that, after allowing for age and duration of diabetes, limited joint mobility was independently associated with Dupuytren's contracture (odds ratio 5...

The article describes indications, preparing and operative technique of partial aponeuroectomy with dissection of the zone of higher afferent innervation of palmar aponeurosis and postoperative treatment of the patients. Two hundred operations were performed under conditions of the out-patient clinic. The I and II degree contractures were successfully treated in 96.7% of the cases. Satisfactory results were obtained in patients with the IIId degree of the disease.

Concerning the question whether a correlation between the vasospasm and morphological changes in the neuro-myo-arterial glomerular (Hoyer-Grosser-Organ) exists also in Dupuytren disease, a series of 18 patients with Dupuytren and 5 patients with Raynaud disease were studied by finger venous occlusion plethysmography and finger tip biopsies. No typical histological changes were found in Dupuytren's Contracture, particularly none in the 13 cases (70%) which had a latent vasospasm and none in the 5 cases (30%) which had a normal plethysmogram, whereas in all the patients with Raynaud disease the typical morphological changes of wall, lumen and morphometric counts of the "Suquet-Hoyer" canals were found in correspondance to the abnormal plethysmogram...