Wuhui Li, Hui Tan, Junmei Liu, Jie Hu, Jialin Cui, Shi Wang, Qingfeng Liu, Fangzhou Hu, Li Ren, Min Tao, Rurong Zhao, Conghui Yang, Qinbo Qin, Shaojun Liu
Spermatogenesis involves a series of cellular transformations and thousands of regulated genes. Previously, we showed that the triploid fish (3nBY) cannot produce mature spermatozoa. In the present study, evaluation of the testis microstructure revealed that germ cells of 3nBY could develop into round spermatids, but then degenerated, resulting in male infertility. In this study we comparatively analysed the testis transcriptomes from 3nBY and its diploid parent YB and identified a series of differentially expressed genes (DEGs) that were enriched in the Wnt signalling pathway and the apoptotic and ubiquitin-mediated proteolysis processes in 3nBY...
August 8, 2018: Reproduction, Fertility, and Development