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Amanda H Plunkett, Mike J Schoonover, Jenna M Young, Jared D Taylor, Todd C Holbrook
OBJECTIVE: To determine the influence of location and movement on subtourniquet pressure (STP) generated by application of a wide-rubber tourniquet (WRT) on equine limbs. STUDY DESIGN: Randomized experimental cross-over design. ANIMALS: Six standing, sedated horses. METHODS: Horses were sedated with detomidine hydrochloride (0.2 μg/kg IV), and 4 investigators applied WRTs to the antebrachium (AB), gaskin (GK), and midmetacarpus (MC) of each horse in a predetermined, randomized order...
February 17, 2019: Veterinary Surgery: VS
Graciela Kearney, Javier Zorrilla de San Martín, Lucas G Vattino, Ana Belén Elgoyhen, Carolina Wedemeyer, Eleonora Katz
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the central nervous system. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs. The MOC-IHC synapse, functional from postnatal day (P)0 to hearing onset (P12), undergoes dramatic changes in the sensitivity to acetylcholine (ACh) and in the expression of key postsynaptic proteins. To evaluate whether there are associated changes in the properties of ACh release during this period, we used a cochlear preparation from mice of either sex at P4, P6-7 and P9-11 and monitored transmitter release from MOC terminals in voltage-clamped IHCs in the whole-cell configuration...
February 12, 2019: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Mohammad H Semreen, Abdallah Shanableh, Lucy Semerjian, Hasan Alniss, Mouath Mousa, Xuelian Bai, Kumud Acharya
The present work describes the optimization and validation of a highly selective and sensitive analytical method using solid phase extraction and liquid chromatography tandem mass spectrometry (SPE LC-MS/MS) for the determination of some frequently prescribed pharmaceuticals in urban wastewater received and treated by Sharjah sewage treatment plant (STP). The extraction efficiency of different SPE cartridges was tested and the simultaneous extraction of pharmaceuticals was successfully accomplished using hydrophilic-lipophilic-balanced reversed phase Waters® Oasis HLB cartridge (200 mg/ 6 mL) at pH 3...
February 11, 2019: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Shuguang Wang, Jialong Pei, Juan Li, Guojian Tang, Jingwei Zhao, Xiaopeng Peng, Shuangxi Nie, Yulong Ding, Changming Wang
Bamboo is one of the fastest growing plants in the world, but their shoot buds develop very slowly. Information about the sugar storage and metabolism during the shoot growth is lacking. In the present study, we determined the activity of sucrose and starch metabolizing enzymes during the developmental period of Fargesia yunnanensis from shoot buds to the young culms that have achieved their full height. The soluble sugars and starch contents were also determined and analyzed in shoot buds and shoots at different developmental stages...
February 11, 2019: Physiologia Plantarum
Miguel E M Udaeta, Guilherme A de S Medeiros, Vinícius O da Silva, Luiz C R Galvão
The objective of this study is to evaluate the potential for electricity generation in the State of São Paulo (SP) from the sewage treatment. A sewage treatment plant (STP) with domain in the production of biogas from wastewater treatment plant (WWTP) is the basis for this case study. The basic premise is that the very generation of electricity in STPs is advantageous for companies in the sanitation sector in Brazil, resulting in cost reductions of the treatment process. Gains at the end of the process are found in two levels, namely: (i) economic, by generating 165% of electricity from biogas burning in relation to the expend; (ii) energy, by adding a new sustainable and storable energy source equivalent to 4% of natural gas offered in the State of SP and 0,5% of electricity produced from biogas burning in relation to electricity consumption...
February 7, 2019: Journal of Environmental Management
Kento Hoshida, Fujio Araki, Takeshi Ohno, Hirofumi Tominaga, Kazuki Komatsu, Kentaro Tamura
The purpose of this study was to verify the accuracy of dose calculation algorithms of a treatment planning system for a single-isocenter volumetric modulated arc therapy (VMAT) plan in multiple brain metastases, by comparing the dose distributions of treatment planning system with those of Monte Carlo (MC) simulations. We used a multitarget phantom containing 9 acrylic balls with a diameter of 15.9 mm inside a Lucy phantom measuring 17 × 17 × 17 cm3 . Seven VMAT plans were created using the multitarget phantom: 1 multitarget plan (MTP) and 6 single target plans (STP)...
February 6, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
Haiyan Qiao, Pengfei Qi, Xiaohui Zhang, Linan Wang, Yeqiang Tan, Zhaohui Luan, Yanzhi Xia, Yan-Hui Li, Kunyan Sui
Herein, we demonstrate that a ternary ionic hydrogel sensor consisting of tannic acid (TA), sodium alginate (SA), and covalent cross-linked polyacrylamide (PAM) as skin-mountable and wearable sensors. Based on the multiple weak H-bonds and synergistic effects between the three components, the as-prepared hybrid hydrogel exhibits ultra-stretchability with high elasticity, good self-healing, excellent conformability, and high self-adhesiveness to diverse substrates both in air and underwater. More importantly, the ternary hydrogel exhibits high strain sensitivity especially under subtle strains with a gauge factor of 2...
January 30, 2019: ACS Applied Materials & Interfaces
Philip Kaloo, Sarah Armstrong, Claire Kaloo, Vanessa Jordan
BACKGROUND: Laparoscopy is a common procedure used to diagnose and treat various gynaecological conditions. Shoulder-tip pain (STP) as a result of the laparoscopy occurs in up to 80% of women, with potential for significant morbidity, delayed discharge and readmission. Interventions at the time of gynaecological laparoscopy have been developed in an attempt to reduce the incidence and severity of STP. OBJECTIVES: To determine the effectiveness and safety of methods for reducing the incidence and severity of shoulder-tip pain (STP) following gynaecological laparoscopy...
January 30, 2019: Cochrane Database of Systematic Reviews
Rohit Kumar, Deepika C Khakha, Sheffali Gulati, Jaya Shankar Kaushik
The aim of study was to assess the combined effectiveness of structured teaching program (STP) and patient information pamphlet (PIS) on caregivers' knowledge with regard to domiciliary management of seizure as compared with PIS alone. Study participants included caregivers of typically developing children aged 1-18 years with at least one episode of convulsion. The enrolled participants were allocated to either of the two groups: intervention group (STP along with PIS) and control group (PIS). The outcome was measured by a structured questionnaire - 'first-aid measures knowledge questionnaire'...
January 22, 2019: Epilepsy & Behavior: E&B
Wei Zhang, Shenyun Wang, Fangwei Yu, Jun Tang, Li Yu, Hong Wang, Jianbin Li
Sugar transporter protein ( STP ) genes are involved in multiple biological processes, such as plant responses to various stresses. However, systematic analysis and functional information of STP family genes in Brassica oleracea are very limited. A comprehensive analysis was carried out to identify BoSTP genes and dissect their phylogenetic relationships and to investigate the expression profiles in different organs and in response to the clubroot disease. A total of 22 BoSTP genes were identified in the B...
January 21, 2019: Genes
Chih-Hsu Huang, Chou-Ching K Lin
When incorporating more realistic synaptic dynamics, the computational efficiency of population density methods (PDMs) declines sharply due to the increase in the dimension of master equations. To avoid such a decline, we develop an efficient PDM, termed colored-synapse PDM (csPDM), in which the dimension of the master equations does not depend on the number of synapse-associated state variables in the underlying network model. Our goal is to allow the PDM to incorporate realistic synaptic dynamics that possesses not only finite relaxation time but also short-term plasticity (STP)...
November 2018: ENeuro
Pevitr S Bansal, Daniel A Waschbusch, Sarah M Haas, Dara E Babinski, Sara King, Brendan F Andrade, Michael T Willoughby
The purpose of this study was to examine whether callous-unemotional (CU) traits moderated the effects of intensive behavior therapy in elementary school-age children with varying levels of conduct problems (CP). Both treatment response (magnitude of change between pre- and posttreatment) and treatment outcomes (likelihood of normalization from treatment) were examined. Participants were 67 children (n = 49 boys, Mage = 9.6 years) with varying levels of CP and CU who participated in an intensive 8-week summer treatment program (STP) in which behavior therapy was delivered to children in recreational and classroom settings and to parents via weekly parent training sessions...
January 2019: Behavior Therapy
Jalil Kardan-Yamchi, Hossein Kazemian, Mehri Haeili, Ahad Ali Harati, Sirus Amini, Mohammad Mehdi Feizabadi
INTRODUCTION: Active extrusion of antituberculosis (TB) drugs using efflux pumps (EPs) has been suggested as a conributing determinant of drug resistance in Mycobacterium tuberculosis (MTB). The present study was conducted to determine the role of 10 drug efflux transporters in devoloping drug resistance in a series of clinical MTB isolates. MATERIAL AND METHODS: A total of 31 clinical isolates of MTB without drug exposure (21 multi/extensively drug- resistant (M/XDR) and 10 drug sensitive isolates) were studied...
January 14, 2019: Journal of Global Antimicrobial Resistance
Shuo Wang, Limin Zhou, Xingya Wang, Chunlei Wang, Yaming Dong, Yi Zhang, Yongxiang Gao, Lijuan Zhang, Jun Hu
The absorption of gas molecules at hydrophobic surface may have a special state and play an important role in many processes in interfacial physics, which has been rarely considered in previous theory. In this paper, force spectroscopic experiments were performed by a nano-sized AFM probe penetrated into the individual surface nanobubbles and contacted with the HOPG substrate. The results showed that the adhesion force at the gas/solid interface was much smaller than that in air measured with the same AFM probe...
January 15, 2019: Langmuir: the ACS Journal of Surfaces and Colloids
Fatemeh Taheriyan, Mohammad Teshnehlab, Shahriar Gharibzadeh
The treatment of chronic pain depends mainly on our understanding of the mechanisms such as central sensitization which is involved in it. Wind-up of spinal cord is one of the most important phenomena in the study of central sensitization which has received considerable attention in recent years. Wind-up is a form of short-term synaptic plasticity (STP) that can lead to central sensitivity. Although several models have been proposed for wind-up, none of them are based on the experimental evidence. In this study, a new network model is introduced according to the gate control theory of pain...
January 11, 2019: Journal of Theoretical Biology
Shi-Liang Wang, Jian-Shu Sun, Yue-Wei Yang, Min Zhang
Perfluoroalkyl acids (PFAAs) are commonly detected in various environmental media and can cause potential risks to the ecological environment and human health. The levels and spatial distribution of 15 types of PFAAs and 3 types of PFAA precursors in the main river water and effluents of three sewage treatment plants (STPs) of Rizhao City were systematically investigated based on methods such as ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), solid phase extraction and enrichment, and hydroxyl radical (·OH) oxidation to explore the pollution characteristics of PFAAs and the contribution of their precursors to environmental pollution in different water bodies of typical tourist cities...
December 8, 2018: Huan Jing Ke Xue= Huanjing Kexue
Shu-Hui Liu, Wei-Jun Tian, Jian-Ren Zhou, Jing Zhao, Zhe Wang
While polycyclic aromatic hydrocarbons (PAHs) are an important persistent toxic organic contaminant, the toxicities of substituted polycyclic aromatic hydrocarbons (SPAHs) are much higher than PAHs. Water and sludge samples were collected from the Qingdao Chengyang Sewage Treatment Plant (STP). The distribution and removal of 16 PAHs and nitro-PAHs (NPAHs), methyl-PAHs (MPAHs), and oxy-PAHs (OPAHs) in the SBR/MBBR process were analyzed. The results showed that 16 PAHs and 13 SPAHs were detected. In the influent water, the total concentrations of PAHs and SPAHs were 3835...
February 8, 2019: Huan Jing Ke Xue= Huanjing Kexue
Yongbeom Cho, Jae Yoon Lee, Eunseon Yu, Jae-Hee Han, Myung-Hyun Baek, Seongjae Cho, Byung-Gook Park
In this work, a study on a semi-floating-gate synaptic transistor (SFGST) is performed to verify its feasibility in the more energy-efficient hardware-driven neuromorphic system. To realize short- and long-term potentiation (STP/LTP) in the SFGST, a poly-Si semi-floating gate (SFG) and a SiN charge-trap layer are utilized, respectively. When an adequate number of holes are accumulated in the SFG, they are injected into the nitride charge-trap layer by the Fowler⁻Nordheim tunneling mechanism. Moreover, since the SFG is charged by an embedded tunneling field-effect transistor existing between the channel and the drain junction when the post-synaptic spike occurs after the pre-synaptic spike, and vice versa, the SFG is discharged by the diode when the post-synaptic spike takes place before the pre-synaptic spike...
January 7, 2019: Micromachines
Gamaliel López-Leal, Julio César Zuniga-Moya, Semiramis Castro-Jaimes, Lucía Graña-Miraglia, Ángeles Pérez-Oseguera, Hilda Sarahi Reyes-García, Simmons David Gough-Coto, René Pavón-Madrid, Suyapa Aurora Bejarano, Annabelle Ferrera, Santiago Castillo-Ramírez, Miguel A Cevallos
Although Acinetobacter baumannii has become one of the most important nosocomial pathogens worldwide, very little is known about the genetic identity of isolates from less developed countries in Latin America. To alleviate this, we sequenced the genomes of 16 A. baumannii isolates from Honduras. Whole-genome sequencing was conducted on 16 isolates from five Honduran Hospitals. With the sequences of these Honduran isolates and other 42 publically available genomes, a maximum likelihood phylogeny was constructed to establish the relationship between the Honduran isolates and those belonging to the International Clones (ICs)...
January 7, 2019: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
Neda Mashhadi, Keith E Taylor, Nathalie Jimenez, Sherin T Varghese, Yaniv Levi, Corinne Lonergan, Emilie Lebeau, Mathilde Lamé, Elodie Lard, Nihar Biswas
Personal care products and pharmaceuticals have been reported in various concentrations in the effluent of municipal sewage treatment plants (STP). Although they are generally found in the nanogram to microgram per liter range, many of them might have adverse health effects on humans at these concentrations. Conventional treatments applied at the STP are unable to effectively remove most of these recalcitrant compounds, thus there is a necessity for development of alternative treatment techniques. In this article, the efficiency of enzymatic treatment using soybean peroxidase in treating some commonly found micropollutants is discussed...
January 3, 2019: Environmental Management
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