keyword
https://read.qxmd.com/read/38447930/is-calcitonin-gene-related-peptide-cgrp-the-missing-link-in-food-histamine-induced-migraine-a-review-of-functional-gut-to-trigeminovascular-system-connections
#1
REVIEW
Fernando de Mora, Karl Messlinger
Calcitonin gene-related peptide (CGRP) and histamine plasma concentrations increase during migraine attacks. Both mediators are potent vasodilators, and they have been shown to reciprocally contribute to the release of each other in the trigeminovascular system, possibly driving migraine development. A high-histamine-content diet triggers migraine in patients who have histamine degradation deficiency owing to diaminooxidase (DAO) gene mutations. Therefore, studying functional links between exogenous histamine and CGRP seems promising for the understanding of diet-induced migraine generation...
March 5, 2024: Drug Discovery Today
https://read.qxmd.com/read/38378909/the-correlation-between-the-frequent-intake-of-dietary-migraine-triggers-and-increased-clinical-features-of-migraine-analytical-cross-sectional-study-from-egypt
#2
JOURNAL ARTICLE
Abdel-Ghaffar I Fayed, Hossam Emam, Alyaa N Abdel-Fattah, Reham M Shamloul, Thanaa A Elkholy, Ensaf M Yassen, Eman Hamdy, Mohie-Eldin T Mohamed, Mahrous I Seddeek, Elsayed Abed
Despite the high prevalence of primary headaches, the role of food in modifying clinical characteristics among migraine patients is often overlooked. The aim is to detect the correlation between adopting unhealthy dietary habits and migraine severity and identify foods that have a greater chance of triggering specific subtypes of migraine. The present study was a cross-sectional analytical study that was conducted at Kasralainy Hospital, Cairo University, headache clinic at Alexandria University Hospital, and Al-Azhar University Hospitals from January to June 2020...
February 20, 2024: Scientific Reports
https://read.qxmd.com/read/38079074/unraveling-the-msg-headache-controversy-an-updated-literature-review
#3
REVIEW
Edmond Ahdoot, Fred Cohen
PURPOSE OF REVIEW: To review the evidence and role of monosodium glutamate (MSG) as a headache and migraine trigger. RECENT FINDINGS: MSG is a common food additive, has widely been linked as a trigger of headache, as well as other symptoms. However, the evidence for MSG as a causative agent for headache is debated. Various clinical trials over the past several decades have reported conflicting results, with studies suggesting that MSG does and does not increase the incidence of headache...
December 11, 2023: Current Pain and Headache Reports
https://read.qxmd.com/read/37892628/distinct-food-triggers-for-migraine-medication-overuse-headache-and-irritable-bowel-syndrome
#4
JOURNAL ARTICLE
Merve Ceren Akgor, Doga Vuralli, Damla Hazal Sucu, Saliha Gokce, Bahar Tasdelen, Fatih Gultekin, Hayrunnisa Bolay
BACKGROUND: Irritable bowel syndrome (IBS) is an under-diagnosed common health problem that impairs quality of life. Migraine and IBS are comorbid disorders that are triggered by foods. We aim to investigate IBS frequency in medication overuse headache (MOH) patients and identify food triggers and food avoidance behavior. METHODS: Participants who completed the cross-sectional, observational and online survey were included ( n = 1118). Demographic data, comorbid disorders, medications used, presence of headache, the diagnostic features of headache and IBS, migraine related subjective cognitive symptoms scale (MigSCog), consumption behavior of patients regarding 125 food/food additives and food triggers were asked about in the questionnaire...
October 12, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37892403/linking-migraine-to-gut-dysbiosis-and-chronic-non-communicable-diseases
#5
REVIEW
Manuela Di Lauro, Cristina Guerriero, Kevin Cornali, Maria Albanese, Micaela Costacurta, Nicola Biagio Mercuri, Nicola Di Daniele, Annalisa Noce
In the world, migraine is one of the most common causes of disability in adults. To date, there is no a single cause for this disorder, but rather a set of physio-pathogenic triggers in combination with a genetic predisposition. Among the factors related to migraine onset, a crucial role seems to be played by gut dysbiosis. In fact, it has been demonstrated how the intestine is able to modulate the central nervous system activities, through the gut-brain axis, and how gut dysbiosis can influence neurological pathologies, including migraine attacks...
October 11, 2023: Nutrients
https://read.qxmd.com/read/37783385/nonallergic-diseases-associated-with-foods
#6
JOURNAL ARTICLE
Priya K Patel, Pornthep Tanpowpong, Panida Sriaroon, Richard F Lockey
Clinicians are faced with evaluating real and alleged reactions to foods that may be allergic or nonallergic. Pathogenesis, diagnosis, and treatment of various non-IgE-mediated diseases are discussed in this review. These food-related conditions range from mild to severe. Referral for an allergy workup may be pursued despite the lack of IgE-mediated symptoms. Diagnostic testing is available for defined non-IgE-mediated food diseases that are either immunologic or nonimmunologic. These include celiac disease and related disorders, carbohydrate maldigestion, pancreatic insufficiency, and histamine intolerance...
September 30, 2023: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/37755364/all-roads-lead-to-the-gut-the-importance-of-the-microbiota-and-diet-in-migraine
#7
REVIEW
Eleonóra Spekker, Gábor Nagy-Grócz
Migraine, a prevalent neurological condition and the third most common disease globally, places a significant economic burden on society. Despite extensive research efforts, the precise underlying mechanism of the disease remains incompletely comprehended. Nevertheless, it is established that the activation and sensitization of the trigeminal system are crucial during migraine attacks, and specific substances have been recognized for their distinct involvement in the pathomechanism of migraine. Recently, an expanding body of data indicates that migraine attacks can be prevented and treated through dietary means...
September 13, 2023: Neurology International
https://read.qxmd.com/read/37750129/epidemiology-of-migraines-in-iraqi-females-emphasis-on-dietary-influence
#8
JOURNAL ARTICLE
Dina T Khafaf, Bilge Meral Koç
Introduction  Migraine is a neurological condition that frequently results in a severe headache. The headache comes in episodes and is occasionally accompanied by nausea, vomiting, and sensitivity to light. Migraines can be caused by a variety of conditions and can last anywhere from three to four hours to several days, with females experiencing them three times more frequently than men. Studies have found some evidence that lifestyle variables, such as nutrition, may play an important role in the emergence of migraines...
August 2023: Curēus
https://read.qxmd.com/read/37686859/association-between-malnutrition-and-migraine-risk-assessed-using-objective-nutritional-indices
#9
JOURNAL ARTICLE
Jong-Ho Kim, Young-Suk Kwon, Jae Jun Lee, Sang-Hwa Lee, Jong-Hee Sohn
Dietary triggers are frequently linked to migraines. Although some evidence suggests that dietary interventions might offer a new avenue for migraine treatment, the connection between migraine and nutrition remains unclear. In this study, we explored the association between nutritional status and migraines. Clinical data spanning 11 years were sourced from the Smart Clinical Data Warehouse. The nutritional statuses of 6603 migraine patients and 90,509 controls were evaluated using the Controlling Nutrition Status (CONUT) score and the Prognostic Nutrition Index (PNI)...
September 1, 2023: Nutrients
https://read.qxmd.com/read/37621269/visually-enhanced-vestibulo-ocular-reflex-gain-in-patients-with-vestibular-disease
#10
JOURNAL ARTICLE
Eric K Kim, Natalie Sienko, Adam Gardi, Roseanne Krauter, Lauren Pasquesi, Jeffrey D Sharon
OBJECTIVE: Vestibular migraine (VM) is a diagnostic challenge. Visually enhanced vestibulo-ocular reflex (VVOR) gain, a measure of the visual-vestibular interaction, has been proposed as a tool for diagnosing VM. This study seeks to evaluate VVOR gain's diagnostic capability to predict VM and to compare the phenotypes of vestibular patients with elevated versus normal/low VVOR gain. METHODS: A retrospective review of consecutive adult patients at a dizziness clinic from October 2016 and December 2020 was conducted...
August 2023: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/37575293/migraine-and-heart-a-reality-check
#11
REVIEW
Jayesh Valecha, Harshwardhan Khandait, Anagha Sk, Vasu Gupta, Sunita Kumawat, Fnu Anamika, Rohit Jain, Dharti Dua
Migraine is a common neurological disorder affecting 12% of the global population. The common risk factors are adolescent age, genetics, and female sex, and are triggered by hormonal fluctuations, emotional stress, sensory overload, weather changes, alcohol consumption, fasting, cheese, chocolate, smoked fish, yeast extract, cured meats, artificial sweeteners, food preservatives containing nitrates and nitrites, and sleep disturbances. Migraine with aura is associated with an increased risk of cardiovascular disease events, such as myocardial infarction, angina pectoris, and cardiac arrhythmias, and has recently been added to the QRISK3 cardiovascular disease prediction score...
August 1, 2023: Global Cardiology Science & Practice
https://read.qxmd.com/read/37513588/caffeine-for-headaches-helpful-or-harmful-a-brief-review-of-the-literature
#12
REVIEW
Anna Zduńska, Joanna Cegielska, Sebastian Zduński, Izabela Domitrz
Consumption of caffeine in the diet, both daily and occasional, has a significant biological effect on the nervous system. Caffeine, through various and not yet fully investigated mechanisms, affects headaches. This is especially noticeable in migraine. In other headaches such as hypnic headache, post-dural puncture headache and spontaneous intracranial hypotension, caffeine is an important therapeutic agent. In turn, abrupt discontinuation of chronically used caffeine can cause caffeine-withdrawal headache...
July 17, 2023: Nutrients
https://read.qxmd.com/read/37435156/triggered-episodic-vestibular-syndrome-and-transient-loss-of-consciousness-due-to-a-retrostyloidal-vagal-schwannoma-a-case-report
#13
Maritta Spiegelberg, Ekin Ermiş, Andreas Raabe, Alexander Andrea Tarnutzer
BACKGROUND: Various conditions may trigger episodic vertigo or dizziness, with positional changes being the most frequently identified condition. In this study, we describe a rare case of triggered episodic vestibular syndrome (EVS) accompanied by transient loss of consciousness (TLOC) linked to retrostyloidal vagal schwannoma. CASE DESCRIPTION: A 27-year woman with known vestibular migraine presented with a 19-month history of nausea, dysphagia, and odynophagia triggered by swallowing food and followed by recurrent TLOC...
2023: Frontiers in Neurology
https://read.qxmd.com/read/37355943/a-study-on-prevalence-of-trigger-factors-and-associated-disorders-in-tension-type-headache
#14
JOURNAL ARTICLE
Deepak Jain, Garima Pandey
OBJECTIVE: To study the prevalence of trigger factors and associated disorders in tension-type headache (TTH). Trigger factors have been widely studied in the context of migraine, but very few studies have investigated trigger factors in the context of TTH. MATERIALS AND METHODS: A total of 400 patients above the age of 15 years fulfilling the third edition of the International Classification of Headache Disorders (ICHD 3) criteria of frequent episodic tension-type headache (FETTH) and chronic tension-type headache (CTTH) were enrolled and evaluated using a questionnaire...
November 2022: Journal of the Association of Physicians of India
https://read.qxmd.com/read/37351190/association-between-dietary-habits-and-the-risk-of-migraine-a-mendelian-randomization-study
#15
JOURNAL ARTICLE
Xinhui Liu, Yuanyuan Yu, Lei Hou, Yifan Yu, Yutong Wu, Sijia Wu, Yina He, Yilei Ge, Yun Wei, Qingxin Luo, Fengtong Qian, Yue Feng, Hongkai Li, Fuzhong Xue
OBJECTIVE: The important contribution of dietary triggers to migraine pathogenesis has been recognized. However, the potential causal roles of many dietary habits on the risk of migraine in the whole population are still under debate. The objective of this study was to determine the potential causal association between dietary habits and the risk of migraine (and its subtypes) development, as well as the possible mediator roles of migraine risk factors. METHODS: Based on summary statistics from large-scale genome-wide association studies, we conducted two-sample Mendelian randomization (MR) and bidirectional MR to investigate the potential causal associations between 83 dietary habits and migraine and its subtypes, and network MR was performed to explore the possible mediator roles of 8 migraine risk factors...
2023: Frontiers in Nutrition
https://read.qxmd.com/read/37321194/migraine-attacks-triggered-by-ingestion-of-watermelon-citrullus-lanatus-a-source-of-citrulline-activating-the-l-arginine-nitric-oxide-pathway
#16
JOURNAL ARTICLE
Raimundo Pereira Silva-Néto, Gabriela Leal Bezerra, Natália Rebeca Alves Araújo, Sângela Fernandes Silva, Suyanne Kássia Soares Pereira, Layana Karine Farias Lima, Adriana Almeida Soares, Luciano Silva Lopes
INTRODUCTION: Ingesting some foods can trigger headache attacks in migraine patients. Diet-sourced citrulline activates the L-arginine-nitric oxide pathway, acting on the pathophysiology of migraine. OBJECTIVES: To characterize the ingestion of watermelon (Citrullus lanatus) as an activating factor of the L-arginine-nitric oxide pathway and as a trigger for headache attacks in patients with migraine. SUBJECTS AND METHODS: The study was a clinical trial, interventional, controlled and with group comparison...
June 15, 2023: European Neurology
https://read.qxmd.com/read/37206912/migraine-triggers-in-asian-countries-a-narrative-review
#17
REVIEW
Chisato Iba, Seiya Ohtani, Mi Ji Lee, Sunjun Huh, Narumi Watanabe, Jin Nakahara, Kuan-Po Peng, Tsubasa Takizawa
BACKGROUND: Migraine is one of the most common neurological disorders worldwide. Clinical characteristics of migraine may be somewhat different across ethnic groups. Although factors such as stress, lack of sleep, and fasting are known as migraine triggers, the discussion about geographical differences of migraine triggers in Asia is lacking. METHODS: In this study, we performed a narrative review on migraine triggers in Asia. We searched PubMed for relevant papers published between January 2000 and February 2022...
2023: Frontiers in Neurology
https://read.qxmd.com/read/36014841/the-pathogenetic-role-of-melatonin-in-migraine-and-its-theoretic-implications-for-pharmacotherapy-a-brief-overview-of-the-research
#18
REVIEW
Anna Zduńska, Joanna Cegielska, Izabela Domitrz
Migraine is a chronic disease of global concern, regardless of socio-economic and cultural background. It most often and intensely affects young adults, especially women. Numerous mechanisms of a migraine attack have been identified (disturbances in the reaction of vessels, functions of neurotransmitters, cortical neurons, ion channels, receptors, the process of neurogenic inflammation), and many of its symptoms can be explained by activation of the hypothalamus and disturbances in its communication with other brain regions (including the brainstem)...
August 15, 2022: Nutrients
https://read.qxmd.com/read/35693360/migraine-prevalence-and-analysis-of-dietary-habits-in-relation-to-headache-in-the-female-population-a-single-center-study-from-jeddah-saudi-arabia
#19
JOURNAL ARTICLE
Yasser S Aladdin, Rawaf Alsharif, Weaam Mattar, Mona Alturki, Israa A Malli, Yara Alghamdi, Atheer Ismail, Bader Shirah
Introduction Lifestyle-related factors including dietary intake can significantly increase the chances of developing migraine. Some components of food items are thought to induce the release of vasoactive substances leading to the dilation of blood vessels, which in turn results in migraine episodes. This research aimed to assess the prevalence of migraine and examine the relation of the headache to the dietary patterns of female students and employees of King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) - Jeddah experiencing migraine attacks as well as to assess the relationship between the migraine attacks and the available dietary items served at the food outlets within the campus...
May 2022: Curēus
https://read.qxmd.com/read/34959985/nutrients-to-improve-mitochondrial-function-to-reduce-brain-energy-deficit-and-oxidative-stress-in-migraine
#20
REVIEW
Michal Fila, Cezary Chojnacki, Jan Chojnacki, Janusz Blasiak
The mechanisms of migraine pathogenesis are not completely clear, but 31 P-nuclear magnetic resonance studies revealed brain energy deficit in migraineurs. As glycolysis is the main process of energy production in the brain, mitochondria may play an important role in migraine pathogenesis. Nutrition is an important aspect of migraine pathogenesis, as many migraineurs report food-related products as migraine triggers. Apart from approved anti-migraine drugs, many vitamins and supplements are considered in migraine prevention and therapy, but without strong supportive evidence...
December 10, 2021: Nutrients
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