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Radiesse vocal cord

Morad Faoury, Steven Frampton, David Allen, Andrea Burgess, Kate Heathcote, Hasnaa Ismail-Koch
Introduction: The impact of unilateral vocal fold palsy (UVFP) on quality of life cannot be underestimated. Management may be complicated by difficulty in determining prognosis. Currently, there is no standardized management pathway for UVFP. Surgery is considered when speech and language therapy has not been successful or when there is significant aspiration and dysphonia. Surgical options for UVFP include injection laryngoplasty, thyroplasty and laryngeal reinnervation. Methods: We report the case of a 6-year-old girl with a left UVFP sustained following PDA ligation...
February 2019: Journal of Surgical Case Reports
K A Stephenson, L Cavalli, A Lambert, J Fleming, E Lawes, S Gupta, C G Jephson, L A Cochrane
INTRODUCTION: Unilateral vocal fold paresis may significantly impair the vocal quality and laryngeal competence of a child. Relatively little literature relates to injection medialisation laryngoplasty (IML) in children and previous reports have involved small numbers of heterogenous cases. METHODS: A retrospective review was conducted of paediatric patients managed by our multidisciplinary specialist voice clinic undergoing IML for unilateral vocal fold paresis...
September 2017: International Journal of Pediatric Otorhinolaryngology
H Mohammed, L Masterson, S Gendy, R Nassif
OBJECTIVE: To assess voice outcomes in patients undergoing vocal fold injection (VFI) augmentation laryngoplasty in a clinic-based setting. METHODS: A prospective study of patients with unilateral vocal cord palsy undergoing Radiesse(®) vocal cord augmentation. We used the ten-item voice handicap index (VHI-10) as a postal survey before and after the intervention. RESULTS: A total of 43 patients were referred to our ENT clinic from June 2011 to October 2014 with unilateral vocal cord palsy...
August 2016: Clinical Otolaryngology
Silvio José de Vasconcelos, Rodrigo Augusto Souza Leão, Sidcley Bernardino-Araújo, Mariana Montenegro de Melo Lira, Domingos Hiroshi Tsuji
PURPOSE: To compare the inflammatory reaction caused by the injection of a sugarcane biopolymer (SCB) into the vocal fold of rabbits with that caused by calcium hydroxyapatite (CaH). METHODS: CaH (Radiesse(r)) and SCB gel were injected respectively into the right and left vocal cords of thirty rabbits. The rabbits were distributed into two equal groups and sacrificed at three and twelve weeks after injection. We then evaluated the intensity of the inflammatory reaction, plus levels of neovascularization, fibrogenesis and inflammatory changes in the vocal mucosa...
March 2015: Acta Cirúrgica Brasileira
Wouter L Lodder, Frederik G Dikkers
OBJECTIVES/HYPOTHESIS: To evaluate the short-term voice outcomes of vocal fold augmentation using fat compared to calcium hydroxylapatite product Radiesse Voice (Merz Aesthetics). STUDY DESIGN: Retrospective study design. METHODS: Sixty-six consecutive patients with vocal fold insufficiency were recruited, including the final 33 patients treated with fat and all 33 patients treated with calcium hydroxylapatite product. Before April 2011, fat augmentation was the standard treatment; from April 2011, only calcium hydroxylapatite product was used...
May 2015: Laryngoscope
Il Ha Moon, Ki Nam Park, Hee Kyung Kim, SeungWon Lee
OBJECTIVE: To demonstrate foreign body and chronic inflammatory reaction of commercially available injection materials using the rabbit vocal fold paralysis model. STUDY DESIGN: Animal study. METHODS: The left recurrent laryngeal nerve was identified and divided at the tracheoesophageal groove. Amounts (100 μL) of phosphate-buffered saline (PBS), polyacrylamide hydrogel (Aquamid; Ferrosan A/S, Søborg, Denmark), calcium hydroxyapatite (Radiesse; BioForm Medical Inc...
January 2015: Journal of Voice: Official Journal of the Voice Foundation
Bari H Ruddy, Teresa E Pitts, Jeff Lehman, Brian Spector, Vicki Lewis, Christine M Sapienza
OBJECTIVES/HYPOTHESIS: This study examined changes in voluntary cough airflow measures immediately following in-office injection of Radiesse in patients diagnosed with glottic insufficiency. Due to significant comorbidities, these patients were poor candidates for medialization under general anesthesia. Each patient presented with dysphonia and dysphagia and ineffective voluntary cough, resulting in a poor clearing of secretions and a presence of ingested fluids on examination. STUDY DESIGN: Prospective cohort and case series study...
July 2014: Laryngoscope
Rebecca S Bartlett, Henry T Hoffman, Seth H Dailey, Jonathan M Bock, Sarah A Klemuk, Ryan W Askeland, Jan S Ahlrichs-Hanson, Andrew C Heaford, Susan L Thibeault
OBJECTIVES/HYPOTHESIS: The purposes of this preclinical study were to investigate histologic and rheologic outcomes of Microendoscopy of Reinke's space (MERS)-guided minithyrotomy and to assess its instrumentation. STUDY DESIGN: Human cadaveric and in vivo animal study. METHODS: Three human cadaveric larynges were treated with MERS-guided placement of Radiesse VoiceGel and immediately evaluated histologically for biomaterial location. In the second part of this investigation, two scarred porcine larynges were treated with MERS-guided placement of HyStem-VF and rheologically evaluated 6 weeks later...
November 2013: Laryngoscope
Seong Keun Kwon, Jae-Jun Song, Chang Gun Cho, Seok-Won Park, Soo Jung Choi, Se Heang Oh, Jin Ho Lee
OBJECTIVES/HYPOTHESIS: The purpose of this study was to explore a novel strategy to restore vocal gap by using polycaprolactone (PCL) spheres with thermosensitive Pluronic F127 in a paralyzed rabbit vocal fold. STUDY DESIGN: In vivo study using a rabbit model. METHODS: The PCL spheres were fabricated by an isolated particle-melting method. The PCL spheres/Pluronic F127 gel mixture was prepared by a simple mixture of PCL and Pluronic F127 solution...
July 2013: Laryngoscope
Enrique Cantillo-Baños, Alfredo Jurado-Ramos, José Gutiérrez-Jódas, Leopoldo Ariza-Vargas
CONCLUSION: The choice of technique will depend on the glottic gap observed by stroboscopy, the alteration of the Voice Handicap Index (VHI) and the recorded values of harmonics-to-noise ratio (HNR), jitter and shimmer, and the general health, age and underlying pathology. There are statistically significant differences between the values of VHI, shimmer and jitter in favour of those cases operated on within 6 months of diagnosis. Alternatives are discussed. OBJECTIVES: This study analysed and compared the functional, morphological and acoustic results, after surgery, through the techniques of medialization thyroplasty and infiltration of biomaterials to correct incomplete closure of the glottis...
March 2013: Acta Oto-laryngologica
Evan M Graboyes, Joseph P Bradley, Bryan F Meyers, Brian Nussenbaum
OBJECTIVES/HYPOTHESIS: The primary objective of this study was to evaluate the effectiveness and safety of injection laryngoplasty using a temporary injectable agent in the acute setting for patients with unilateral vocal cord paralysis following thoracic surgical procedures. STUDY DESIGN: Retrospective consecutive case series in an academic institution. METHODS: Inclusion criteria included patients acutely treated with injection laryngoplasty from January 1, 2006, to March 31, 2010, for a unilateral vocal cord paralysis that occurred after a thoracic surgical procedure (N = 20)...
November 2011: Laryngoscope
Michael S Cohen, Deepak K Mehta, Raymond C Maguire, Jeffrey P Simons
OBJECTIVE: To review our experience with vocal fold injection medialization in children. DESIGN: Retrospective case series. SETTING: Tertiary care academic children's hospital. PATIENTS: All pediatric patients at our institution who underwent injection laryngoplasty for vocal fold medialization from 2003 to 2009. MAIN OUTCOME MEASURES: Age, sex, indication for injection, injection material, surgical and anesthetic technique, outcomes including effect on voice and swallowing, and complications...
March 2011: Archives of Otolaryngology—Head & Neck Surgery
Miwako Kimura, Ted Mau, Roger W Chan
OBJECTIVES/HYPOTHESIS: The purpose of this study was to examine the functional biomechanical properties of several injectable biomaterials currently or potentially used for vocal fold augmentation. STUDY DESIGN: Rheometric investigation of phonosurgical materials in vitro. METHODS: Linear viscoelastic shear properties of 3% bovine collagen (atelocollagen), micronized AlloDerm (Cymetra; LifeCell Corp., Branchburg, NJ), calcium hydroxylapatite (CaHA) (Radiesse; BioForm Medical, San Mateo, CA), and 2...
April 2010: Laryngoscope
Patricio F Jacovella
Radiesse (Bioform Inc, USA) is a sterile, latex-free, non-pyrogenic, semi-solid, cohesive subdermal, injectable implant, whose principal component is synthetic calcium hydroxylapatite, a biocompatible material with over 20 years of use in medicine. The semi-solid nature of the product is created by suspending calcium hydroxylapatite microspheres of 25-45 microns diameter in a gel carrier of carboxymethylcellulose. The product has FDA approval for esthetic facial augmentation in the US. Such approval includes the long-lasting correction of moderate to severe facial wrinkles and folds and the treatment of facial fat loss due to immunodeficiency virus infection...
2008: Clinical Interventions in Aging
Trace Caton, Susan L Thibeault, Sarah Klemuk, Marshall E Smith
OBJECTIVES: The purpose of this study was to measure and compare biomechanical properties of commonly used vocal fold injectates Cymetra, Radiesse, Restylane, Hylaform, and one investigational injectate, Carbylan-GSX 5%, to determine suitability for mucosal injection. STUDY DESIGN: Rheologic investigation. METHODS: Oscillatory shear stress was applied to five samples of each injectate using a parallel plate controlled stress rheometer. Shear stress, shear strain, and strain rate associated with the oscillatory shear deformation were computed from the prescribed torque and measured angular velocity; viscoelastic data were obtained on the basis of these functions...
March 2007: Laryngoscope
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