Use the keywords feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#1
JOURNAL ARTICLE
Bartek Rajwa, Md Mobasshir Arshed Naved, Mohammad Adibuzzaman, Ananth Y Grama, Babar A Khan, M Murat Dundar, Jean-Christophe Rochet
As the world emerges from the COVID-19 pandemic, there is an urgent need to understand patient factors that may be used to predict the occurrence of severe cases and patient mortality. Approximately 20% of SARS-CoV-2 infections lead to acute respiratory distress syndrome caused by the harmful actions of inflammatory mediators. Patients with severe COVID-19 are often afflicted with neurologic symptoms, and individuals with pre-existing neurodegenerative disease have an increased risk of severe COVID-19. Although collectively, these observations point to a bidirectional relationship between severe COVID-19 and neurologic disorders, little is known about the underlying mechanisms...
April 2024: PLOS Digit Health
#2
JOURNAL ARTICLE
Alexander Leff, Catherine Doogan, John Bentley, Bani Makkar, Luisa Zenobi-Bird, Amy Sherman, Simon Grobler, Jennifer Crinion
BACKGROUND: The field of human expert performance teaches us that high quality, high-dose guided practice is required to make large gains in cognitively driven acts. The same also seems to be true for people with acquired brain injury, yet therapy services for people with aphasia (PWA) have traditionally not been designed with this in mind. Intensive Comprehensive Aphasia Programmes (ICAPs) are one way to address the chronic under-dosing of therapy that most PWA experience. AIMS: There are several ways to deliver an ICAP; here we describe two iterations of our Queen Square ICAP...
December 6, 2023: Aphasiology
#3
JOURNAL ARTICLE
Yanchang Shang, Shuhui Wang, Chao Wei, Hengge Xie
This study explored the association between diabetes, cognitive imFpairment (CI), and mortality in a cohort of 2931 individuals aged 60 and above from the 2011 to 2014 NHANES. Mortality data was gathered through 2019, and multivariable Cox proportional hazards models were used to determine the association between diabetes, CI, and mortality adjusting for sociodemographic characteristics, lifestyle factors, and comorbidity conditions. The study spanned up to 9.17 years, observing 579 deaths, with individuals having both diabetes and CI showing the highest all-cause mortality (23...
April 23, 2024: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
#4
JOURNAL ARTICLE
Meng Sun, Zhibin Chen, Guoyi Li, Yingfeng Weng, Yangbo Hou
Abstract： Objective: To explore the relationship between risk factors of cognitive dysfunction and blood pressure variability after acute ischemic stroke in northwest Shanghai to establish a model for early identification of high-risk groups of cognitive dysfunction and formulation of more targeted prevention and treatment measures. Methods: Spearman test was used to evaluate the correlation between blood pressure variability and Montreal Cognitive Assessment (MoCA) score in patients with acute ischemic stroke and the partial regression coefficient model was constructed based on the above independent risk factors, and the receiver operating characteristic (ROC) curve was described to analyze the relevant independent risk factors...
April 23, 2024: International Journal of Neuroscience
#5
JOURNAL ARTICLE
Kevin Pacheco-Barrios, Paulo E P Teixeira, Daniela Martinez-Magallanes, Moacir Silva Neto, Elly Angelica Pichardo, Lucas Camargo, Daniel Lima, Alejandra Cardenas-Rojas, Felipe Fregni
BACKGROUND: The different clinical presentations of fibromyalgia (FMS) may play independent roles in the unclear etiology of cognitive impairments and depressive symptoms seen in this population. Understanding how these clinical presentations are associated with FMS's clinical and neurophysiological aspects is important when developing effective treatments. AIM: To explore the relationship between memory complaints and depressive symptoms, and the different clinical and neurophysiological characteristics of FMS...
April 23, 2024: Pain Medicine
#6
JOURNAL ARTICLE
I R Jackson, E Perugia, M A Stone, G H Saunders
The use of face coverings can make communication more difficult by removing access to visual cues as well as affecting the physical transmission of speech sounds. This study aimed to assess the independent and combined contributions of visual and auditory cues to impaired communication when using face coverings. In an online task, 150 participants rated videos of natural conversation along three dimensions: (1) how much they could follow, (2) how much effort was required, and (3) the clarity of the speech. Visual and audio variables were independently manipulated in each video, so that the same video could be presented with or without a superimposed surgical-style mask, accompanied by one of four audio conditions (either unfiltered audio, or audio-filtered to simulate the attenuation associated with a surgical mask, an FFP3 mask, or a visor)...
April 23, 2024: Cognitive Research: Principles and Implications
#7
REVIEW
Junji Hatakeyama, Kensuke Nakamura, Hidenori Sumita, Daisuke Kawakami, Nobuto Nakanishi, Shizuka Kashiwagi, Keibun Liu, Yutaka Kondo
The importance of ongoing post-discharge follow-up to prevent functional impairment in patients discharged from intensive care units (ICUs) is being increasingly recognized. Therefore, we conducted a scoping review, which included existing ICU follow-up clinic methodologies using the CENTRAL, MEDLINE, and CINAHL databases from their inception to December 2022. Data were examined for country or region, outpatient name, location, opening days, lead profession, eligible patients, timing of the follow-up, and assessment tools...
April 23, 2024: Journal of Anesthesia
#8
REVIEW
Şerife Ayten, Saniye Bilici
PURPOSE OF REVIEW: The gut microbiota plays a crucial role in the pathogenesis of neuroinflammation and Alzheimer's and Parkinson's diseases. One of the main modulators of the gut microbiota is the diet, which directly influences host homeostasis and biological processes. Some dietary patterns can affect neurodegenerative diseases' progression through gut microbiota composition, gut permeability, and the synthesis and secretion of microbial-derived neurotrophic factors and neurotransmitters...
April 23, 2024: Current Nutrition Reports
#9
JOURNAL ARTICLE
Katerina Deike, Andreas Decker, Paul Scheyhing, Julia Harten, Nadine Zimmermann, Daniel Paech, Oliver Peters, Silka D Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Okka Kimmich, Jens Wiltfang, Claudia Bartels, Niels Hansen, Frank Jessen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H Munk, Annika Spottke, Nina Roy, Michael Wagner, Sandra Roeske, Michael T Heneka, Frederic Brosseron, Alfredo Ramirez, Laura Dobisch, Steffen Wolfsgruber, Luca Kleineidam, Renat Yakupov, Melina Stark, Matthias C Schmid, Moritz Berger, Stefan Hetzer, Peter Dechent, Klaus Scheffler, Gabor C Petzold, Anja Schneider, Alexander Effland, Alexander Radbruch
OBJECTIVES: Impaired perivascular clearance has been suggested as a contributing factor to the pathogenesis of Alzheimer disease (AD). However, it remains unresolved when the anatomy of the perivascular space (PVS) is altered during AD progression. Therefore, this study investigates the association between PVS volume and AD progression in cognitively unimpaired (CU) individuals, both with and without subjective cognitive decline (SCD), and in those clinically diagnosed with mild cognitive impairment (MCI) or mild AD...
April 23, 2024: Investigative Radiology
#10
JOURNAL ARTICLE
Giovanna Coriale, Mauro Ceccanti, Marco Fiore, Francesca Tarani, Ginevra Micangeli, Michela Menghi, Adele Minutillo, Paolo Berretta, Giampiero Ferraguti, Angela Iannitelli, Giovanni Parlapiano, Roberto Paparella, Marisa Patrizia Messina, Mario Vitali, Daniela Fiorentino, Simona Pichini, Luigi Tarani
INTRODUCTION: Prenatal alcohol exposure causes a variety of impairments to the fetus called Fetal Alcohol Spectrum Disorders (FASD). Since it is very difficult to identify women that consume alcohol during pregnancy, different methods have been studied to evaluate alcohol exposure. Ethyl Glucuronide (EtG) and Fatty Acid Ethyl Esters (FAEEs) are commonly used to measure alcohol consumption in individuals at-risk for alcohol abuse, including pregnant women. MATERIALS AND METHODS: We conducted a study of two cohorts of 1...
2024: Rivista di Psichiatria
#11
JOURNAL ARTICLE
Melmar Folloso, Steven Villaraza, Yi-Wen Lo, Pek-Lan Khong, Tomotaka Tanaka, Saima Hilal, Narayanaswamy Venketasubramanian, Christopher Li-Hsian Chen
BACKGROUND: There are major challenges in determining the aetiology of vascular cognitive impairment (VCI) clinically, especially in the presence of mixed pathologies, such as vascular and amyloid. Most recently, two criteria (American Heart Association/American Stroke Association [AHA/ASA] and Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition [DSM-V]) have been proposed for the clinical diagnosis of VCI but have not as yet been validated using neuroimaging. AIMS: This study aims to determine whether the AHA/ASA and DSM-V criteria for VCI can distinguish between cases with predominantly vascular pathology and cases with mixed pathology...
April 23, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
#12
JOURNAL ARTICLE
Mirthe Coenen, Floor A S de Kort, Nick A Weaver, Hugo J Kuijf, Hugo Paul Aben, Hee-Joon Bae, Régis Bordet, Christopher Lh Chen, Anna Dewenter, Thomas Doeven, Thibaut Dondaine, Marco Duering, Rong Fang, Ruben S van der Giessen, Jonguk Kim, Beom Joon Kim, Paul L M de Kort, Peter Koudstaal, Minwoo Lee, Jae-Sung Lim, Renaud Lopes, Robert J van Oostenbrugge, Julie Staals, Kyung-Ho Yu, Geert Jan Biessels, J Matthijs Biesbroek
BACKGROUND: Post-stroke cognitive impairment (PSCI) occurs in up to 50% of stroke survivors. Presence of pre-existing vascular brain injury, in particular the extent of white matter hyperintensities (WMH), is associated with worse cognitive outcome after stroke, but the role of WMH location in this association is unclear. AIM: We determined if WMH in strategic white matter tracts explain cognitive performance after stroke. METHODS: Individual patient data from 9 ischemic stroke cohorts with MRI were harmonized through the Meta VCI Map consortium...
April 23, 2024: International Journal of Stroke: Official Journal of the International Stroke Society
#13
REVIEW
Beisi Zheng, Jianer Chen, Manting Cao, Yujia Zhang, Shishi Chen, Hong Yu, Kang Liang
BACKGROUND: Growing evidence suggests that cognitive dysfunction significantly impacts patients' quality of life. Intermittent theta burst stimulation (iTBS) has emerged as a potential intervention for cognitive dysfunction. However, consensus on the iTBS protocol for cognitive impairment is lacking. METHODS: We conducted searches in the Cochrane Central Register of Controlled Trials, EMBASE, PubMed, Chinese National Knowledge Infrastructure, Wanfang Database and the Chongqing VIP Chinese Science and Technology Periodical Database from their inception to January 2024...
April 23, 2024: Brain Injury
#14
JOURNAL ARTICLE
Alixe H M Kilgour, Matthew Rutherford, Joanna Higson, Samantha J Meredith, Jessica McNiff, Stephanie Mitchell, Anusan Wijayendran, Stephen E R Lim, Susan D Shenkin
BACKGROUND: Physical activity (PA) has multiple benefits for older adults (≥70 years old). Despite this many older adults do not undertake the World Health Organisation guideline recommended amount of PA. This systematic review examines barriers and motivators to PA in adults aged ≥70 years. METHODS: We analysed the quantitative literature, including observational studies and baseline data from randomised controlled trials. Studies examining specific diseases (e...
April 1, 2024: Age and Ageing
#15
JOURNAL ARTICLE
Xiao-Jun Jing, Zhi-Yuan Zan, Xin Zhou, Yong-Lan Xiong, Shu-Jiang Ren, Hua Zhang
BACKGROUND: Advances in blood biomarker discovery have enabled the improved diagnosis and prognosis of Alzheimer's disease (AD). Most branched-chain amino acids, except isoleucine (Ile), are correlated with both mild cognitive impairment (MCI) and AD. Therefore, this study investigated the association between serum Ile levels and MCI/AD. METHODS: This study stratified 700 participants from the Alzheimer's Disease Neuroimaging Initiative database into four diagnostic groups: cognitively normal, stable MCI, progressive MCI, and AD...
April 23, 2024: Annals of geriatric medicine and research
#16
JOURNAL ARTICLE
Tahani Saker Sheikh, Ayal Rozenberg, Goni Merhav, Alla Shifrin, Polina Stein, Shahar Shelly
BACKGROUND AND OBJECTIVES: Primary CNS vasculitis (PCNSV) is a rare inflammatory disorder that affects the blood vessels of the central nervous system (CNS). We aimed to analyze the neurological presentations, clinical follow-up, and long-term outcomes of patients with primary central nervous system vasculitis. METHODS: We conducted a retrospective analysis of medical records to assess the neurological presentation, rate of remission, and functional status at the last follow-up in patients with primary central nervous system vasculitis seen in our center in the last 13 years (2010-2023)...
2024: Frontiers in Neurology
#17
JOURNAL ARTICLE
Prabhudas Nelaturi, Sangeetha P Kadamani, Ravikumar Sambandam
BACKGROUND: Hepatic encephalopathy (HE) is a complex neuropsychiatric disorder indicated by a deterioration in the functioning of hepatocytes. Impaired brain function is observed in advanced alcoholic liver disease particularly manifesting as HE. The pathophysiology of alcohol-related HE remains unclear. Accordingly, this study aimed to assess alcoholism and socioeconomic status of patients with liver disease compared with stages of HE. METHODS: This cross-sectional study was conducted on 62 alcoholic patients who have been consuming alcohol for more than 14 years...
February 2024: Addiction & Health
#18
JOURNAL ARTICLE
Osama A Abulseoud, Elisabeth C Caparelli, Janina Krell-Roesch, Yonas E Geda, Thomas J Ross, Yihong Yang
BACKGROUND: We investigated a potential sex difference in the relationship between alcohol consumption, brain age gap and cognitive function in older adults without cognitive impairment from the population-based Mayo Clinic Study of Aging. METHODS: Self-reported alcohol consumption was collected using the food-frequency questionnaire. A battery of cognitive testing assessed performance in four different domains: attention, memory, language, and visuospatial. Brain magnetic resonance imaging (MRI) was conducted using 3-T scanners (Signa; GE Healthcare)...
2024: Frontiers in Psychiatry
#19
JOURNAL ARTICLE
Hongying Huang, Jinchen Li, Jingyi Shen, Tong Zhao, Rong Xiao, Weiwei Ma
BACKGROUND AND OBJECTIVE: Cognitive dysfunction is highly prevalent in obese people, and food is a key factor in obesity, and dietary inflammatory index (DII) can reflect whether diet has anti-inflammatory or pro-inflammatory potential. In addition, dietary fatty acid consumption is linked to inflammation, obesity, and cognitive impairment. Erythrocyte membrane fatty acids can reflect dietary fatty acid intake. Our hypothesis was that erythrocyte membrane fatty acids might have a significant impact on the relationship between DII and cognition in obese individuals, and we designed experiments to test the hypothesis...
2024: Journal of Inflammation Research
#20
JOURNAL ARTICLE
Fereshteh Jahanbani, Justin Cyril Sing, Rajan Douglas Maynard, Shaghayegh Jahanbani, Janet Dafoe, Whitney Dafoe, Nathan Jones, Kelvin J Wallace, Azuravesta Rastan, Holden T Maecker, Hannes L Röst, Michael P Snyder, Ronald W Davis
INTRODUCTION: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) presents substantial challenges in patient care due to its intricate multisystem nature, comorbidities, and global prevalence. The heterogeneity among patient populations, coupled with the absence of FDA-approved diagnostics and therapeutics, further complicates research into disease etiology and patient managment. Integrating longitudinal multi-omics data with clinical, health,textual, pharmaceutical, and nutraceutical data offers a promising avenue to address these complexities, aiding in the identification of underlying causes and providing insights into effective therapeutics and diagnostic strategies...
2024: Frontiers in Immunology
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
