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medical reports

Johannes Westhofen, Marie-Therese Puth, Henrike Steudel, Eva Münster, Klaus Weckbecker
OBJECTIVE: For the first time, the level of knowledge and attitude towards vaccinations in general as well as seasonal influenza vaccination of midwife trainees in Germany was assessed. METHODS: The cross-sectional study was conducted between May and July 2017. The written standardized questionnaire was completed by all midwife-trainees in North Rhine-Westphalia. The statistical analysis included frequency tables and multiple logistic regression models. RESULTS: All of the 10 Schools for Midwifery in North Rhine-Westphalia participated in the survey and 315 questionnaires (response rate: 95...
February 20, 2019: Das Gesundheitswesen
Uwe Schmidt, Claudia Capek, Cahit Birdir, Christine Erfurt, Katharina Nitzsche
INTRODUCTION: It can be observed that there is an increase in the methamphetamine (MA) consumption in Saxony (Federal Republic of Germany). There is so far no data available in German speaking countries about the risk of MA consumption in pregnancy or delivery. METHODS: The data from all pregnant women who were examined or delivered at the Clinic for Obstetrics and Gynaecology between 2010-2015 were retrospectively searched for MA consumption. 119 pregnancies with 113 deliveries of 115 women consuming MA could be evaluated...
February 20, 2019: Zeitschrift Für Geburtshilfe und Neonatologie
Sara Post, Henry A Spiller, Thitphalak Chounthirath, Gary A Smith
CONTEXT: Kratom, or Mitragyna speciosa, is a plant indigenous to Southeast Asia that has gained national attention in the United States for its increased use in the self-management of opioid withdrawal and pain, as well as for concerns about its safety. METHODS: This study analyzes exposures to kratom reported to poison control centers (PCCs) in the United States during 2011-2017 from the National Poison Data System (NPDS). DISCUSSION: From 2011 through 2017, 1807 kratom exposures were reported to United States PCCs...
February 20, 2019: Clinical Toxicology
Rick D Vavolizza, David F Grabski, Daniel E Levin, Jeffrey W Gander
BACKGROUND: Gastrostomy tube (GT) placement is a common pediatric surgical procedure typically indicated for oral aversion. This may develop in patients with congenital heart disease (CHD) who require an orthotopic heart transplant (OHT). The safety profile of GT placement in OHT patients who are immunosuppressed is unknown. Given the potential increased risk of wound site complications on a patient receiving immunosuppression, we sought to determine the safety profile of GT placement in pediatric patients with OHT...
February 20, 2019: Pediatric Transplantation
Mümin Mehmet Koç, Naim Aslan, Alexander P Kao, Asa H Barber
X-ray computed tomography is a strong tool that finds many applications both in medical applications and in the investigation of biological and nonbiological samples. In the clinics, X-ray tomography is widely used for diagnostic purposes whose three-dimensional imaging in high resolution helps physicians to obtain detailed image of investigated regions. Researchers in biological sciences and engineering use X-ray tomography because it is a nondestructive method to assess the structure of their samples. In both medical and biological applications, visualization of soft tissues and structures requires special treatment, in which special contrast agents are used...
February 20, 2019: Microscopy Research and Technique
Saurav Ghimire, Kenneth Lee, Matthew D Jose, Ronald L Castelino, Syed Tabish R Zaidi
AIMS AND OBJECTIVES: To explore clinician assessment of patient adherence, and identify strategies to improve adherence assessment practices in haemodialysis settings. BACKGROUND: Patients with chronic kidney disease undergoing haemodialysis are typically prescribed complex regimens; as such, they are at high risk of medication nonadherence. Current clinical practices focus on prescribing medications, however, little attention is paid to measuring and ensuring patient adherence to their prescribed treatments...
February 20, 2019: Journal of Clinical Nursing
Sung Han Kim, Jung Kwon Kim, Eun Young Park, Jungnam Joo, Kang Hyun Lee, Ho Kyung Seo, Jae Young Joung, Jinsoo Chung
OBJECTIVE: This study aimed to determine the prognostic factors of progression-free survival (PFS) and overall survival (OS) in non-nephrectomized patients with synchronous metastatic renal cell carcinoma (mRCC) receiving first-line vascular endothelial growth factor (VEGF)-targeted therapy or immunotherapy. METHODS: Of 70 patients, 57 (81.4%) were treated with targeted therapy, including 5 (7.1%) with previous immunotherapy and 13 (18.6%) with immunotherapy only...
2019: PloS One
Luana Nice da Silva Oliveira, Alexander Itria, Erika Coutinho Lima
BACKGROUND: Studies on dengue related to the cost of illness and cost of the program are factors to describe the economic burden of dengue, a neglected disease that has global importance in public health. These studies are often used by health managers in optimizing financial resources. A systematic review of studies estimating the cost of dengue was carried out, comparing the costs between the studies and examining the cost drivers regarding the methodological choices. METHODS: This study was done according to the guidelines of the Centre for Reviews and Dissemination (CRD)...
2019: PloS One
Hyeongsuk Lee, Jeongeun Kim, Sukwha Kim, Hyoun-Joong Kong, Hyeongju Ryu
BACKGROUND: Development of a point-of-care (POC) consultation system based on telepresence robots is needed to enable effective decision-making by medical staff at care sites. INTRODUCTION: This study aimed to identify essential features and functional requirements of teleconsultation robot systems and predict potential administrative and clinical issues. MATERIALS AND METHODS: Surveys were conducted with 90 health care professionals and additional focus group interviews with 4 physicians and 5 nurses...
February 20, 2019: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
David A Hashemi, Zoe O Brown-Joel, Elizabeth Tkachenko, Caroline A Nelson, Megan H Noe, Sotonye Imadojemu, Ruth Ann Vleugels, Arash Mostaghimi, Karolyn A Wanat, Misha Rosenbach
Importance: Necrobiosis lipoidica (NL) is a rare granulomatous condition. Current knowledge of its key features is based on a limited number of studies and case reports, leading to wide variability in the characterization of its defining features, with limited comparison of patients with or without diabetes. Objective: To evaluate the epidemiologic characteristics, clinical features, and disease associations of NL in patients with or without type 1 or 2 diabetes...
February 20, 2019: JAMA Dermatology
Adauto Castelo, Carlos Eduardo Brandão Mello, Rosangela Teixeira, Jose Valdez Ramalho Madruga, Tania Reuter, Leila Maria Moreira Beltrão Pereira, Giovanni Faria Silva, Mario Reis Álvares-DA-Silva, Heverton Zambrini, Paulo Roberto Abrão Ferreira
BACKGROUND: Infection by hepatitis C virus is one of the leading causes of chronic hepatitis C and cause severe burden for patients, families and the health care system. OBJECTIVE: The aims of this research were to assess the severity of liver fibrosis, comorbidities and complications of hepatitis C virus; to examine health-related quality of life (HRQoL), productivity loss and resource use and costs in a sample of Brazilian chronic hepatitis C, genotype 1, patients...
October 2018: Arquivos de Gastroenterologia
Adriane Kênia Moreira Silva, Dayane Carlos Mota da Costa, Adriano Max Moreira Reis
OBJECTIVE: To investigate the use of fall-risk-increasing drugs among patients with falls reported to the Patient Safety Office of a hospital, and to identify the factors associated with high risk for fall. METHODS: A cross-sectional study, carried out in a teaching hospital. The study population was the universe of fall reports received by the Patient Safety Office. The dependent variable was a high risk for falls. The Medication Fall Risk Score was used to measure fall risk...
February 14, 2019: Einstein
I M Bensenor
Thyroid disorders are common diseases, both in Brazil and worldwide. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) is a prospective cohort study that investigates cardiovascular diseases, diabetes, and associated factors, including non-classical cardiovascular risk factors such as thyroid function. Thyroid function was classified according to thyrotropin stimulating hormone (TSH), free thyroxine (FT4), and use of medication to treat thyroid disorders, after excluding participants who reported use of any medication that could alter the results of the TSH and FT4 tests...
February 14, 2019: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
José Francisco Aguilar Guevara, Seila Lacarra Fernández, Oliver Rojas Claros, Pedro Giral Villalta, José Luis Cebrián Lostal, Miguel Angel Resano Abarzuza
Kaposi sarcoma is an angioproliferative disorder that ranges from a single indolent skin lesion to respiratory and gastrointestinal/visceral involvement. Kaposi sarcoma is rare in non-immunosuppressed patients. Nineteen cases of penile Kaposi sarcoma in HIV-negative patients were reported in 2012. We present the case report of a 48-year-old male patient with no previous medical history, who came to our urology clinic presenting a purple-color papule on the penis glans. Lab tests revealed negative serology for HIV, but tissue PCR was positive for human herpesvirus 8...
February 18, 2019: Einstein
Kathleen N Fenton, Frank Molloy, William M Novick
BACKGROUND: It has become increasingly apparent that only the truly effective humanitarian work emphasises empowering local practitioners. One problem, though, is that we are often seen as the "experts" who have come to "save" the children. This perception may adversely affect the confidence in the country's own providers. METHODS: Non-profit organisations performing paediatric heart surgery in developing countries were identified from two sources: the CTSnet "volunteerism" web page and an Internet search using the term "Pediatric Heart Surgery Medical Mission...
February 2019: Cardiology in the Young
Kanzo Suzuki, Kyoko Kondo, Masakazu Washio, Sakae Kan, Seiichiro Imai, Kunihiko Yoshimura, Chiharu Ota, Satoko Ohfuji, Wakaba Fukushima, Yoshio Hirota, Kei Nakashima
At present, there are few reports that have clarified the effectiveness of 23-valent pneumococcal polysaccharide vaccine (PPSV23) against all-cause pneumonia or pneumococcal pneumonia in community-acquired pneumonia (CAP) in older individuals in Japan. We conducted a hospital-based matched case-control study to investigate separately the preventive effects of PPSV23 and trivalent influenza vaccine (TIV) on all-cause CAP and pneumococcal CAP in older individuals in Japan. Cases were individuals aged 65 years or older who were newly diagnosed with CAP from October 2010 to September 2014...
February 20, 2019: Human Vaccines & Immunotherapeutics
Cassandra J Enzler, Shioban Torres, Jennifer Jabson, Arin Ahlum Hanson, Deborah J Bowen
OBJECTIVE: The purpose of this study was to compare provider and patient views from the same clinical settings on issues raised by low socioeconomic status (SES) breast cancer survivors. METHODS: We conducted qualitative interviews among two groups: low SES breast cancer survivors (n=37) and medical personnel (ie, physicians, nurses, navigators; n=8) that interact and serve with these patients from two geographically distinct low resourced clinical settings. These semi-structured qualitative interviews used grounded theory to identify several potential themes, such as finances, resources, and medical care...
February 20, 2019: Psycho-oncology
Nehal M Elsherbiny, Eman Ahmed, Ghada Abdel Kader, Yousra Abdel-Mottaleb, Mohamed H ElSayed, Amal M Youssef, Sawsan A Zaitone
Anti-epileptic medications are included in the international guidelines for managing neuropathic pain. Valproate sodium (VPS) was recently described as "the forgotten analgesic" and has been reported to relief pain in various models of neuropathic pain. Some studies reported anti-inflammatory and histone deacetylase 1 (HDA1) inhibitory properties for sodium valproate. The aim of the current study was to investigate the modulatory effect of VPS on pain behavior and inflammatory reactions in alloxan-induced diabetic neuropathy focusing on HDA1 inhibition and glia reactivity...
February 18, 2019: International Immunopharmacology
David Dufresne, Kathleen Dubovec, Norman K So, Prakash Kotagal
PURPOSE: Oral biting injuries are widely recognized complications of seizures. Value in differentiating epileptic vs paroxysmal non-epileptic seizures is well demonstrated, but frequency and semiological value are poorly described. We aimed to evaluate frequency in an epilepsy monitoring unit setting as well as semiological value. MATERIAL AND METHODS: Systematic evaluation of ictal oral injuries was provided by the nursing staff on the Epilepsy Monitoring Unit...
February 14, 2019: Seizure: the Journal of the British Epilepsy Association
Allison R Bechard, Lori A Knackstedt
BACKGROUND: Cocaine use disorder is a significant public health problem and currently no medications are FDA-approved to reduce cocaine relapse. Drug-associated cues are reported to elicit craving and cocaine-seeking in humans. Repeated, non-reinforced presentations of drug-associated cues (cue extinction) have been proposed to reduce the ability of such cues to prompt drug-seeking. In rodent models of cocaine relapse, cue extinction reduces cocaine relapse when such extinction occurs in the same context as cocaine self-administration, which is not akin to the manner in which treatment would occur in humans...
February 13, 2019: Drug and Alcohol Dependence
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