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https://read.qxmd.com/read/30777620/carotid-intima-media-thickness-and-carotid-plaque-a-pilot-study-of-risk-factors-in-an-indigenous-nigerian-population
#1
Ofonime N Ukweh, Ernest U Ekpo
BACKGROUND: Risk factors for carotid intima-media thickness (cIMT) and carotid plaque (CP) differ by ethnicity; however, this is not well understood in some ethnic populations. This work examines the risk factors for cIMT and CP in an indigenous Nigerian population. METHODS: We assessed cIMT and CP in 122 participants and then performed biochemical analysis: fasting blood glucose (FBG), hemoglobin A1c, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), and total cholesterol (TC)...
February 15, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/30771228/update-in-the-classification-and-the-role-of-intra-arterial-stenting-in-the-management-of-carotid-body-paragangliomas
#2
Sampath Chandra Prasad, Melissa Laus, Saeed Al-Ghamdi, Ashish Vashishth, Paolo Piazza, Mario Sanna
BACKGROUND: To review the Shamblin classification of carotid body paragangliomas (CBPs) and the role of intra-arterial stenting in their surgical management. METHODS: Retrospective case series of 20 patients with 28 CBPs that were surgically resected at our center. Intra-arterial stenting was performed in Shamblin II and II classes. RESULTS: The mean follow-up was 47.8 months. Five (17.9%) tumors were Shamblin class I, 15 (53.6%) were class II, and 8 (28...
February 16, 2019: Head & Neck
https://read.qxmd.com/read/30770289/obesity-visceral-adiposity-and-carotid-atherosclerosis
#3
Maciej Haberka, Michael Skilton, Małgorzata Biedroń, Karolina Szóstak-Janiak, Małgorzata Partyka, Monika Matla, Zbigniew Gąsior
Carotid artery atherosclerosis is a complex and multifactorial chronic disease. Our aim was to assess the associations between obesity, fat depots and carotid artery stenosis (CAS) in patients with high cardiovascular (CV) risk. METHODS: The study group included 391 patients (F/M: 136/255 pts.; age: 61.8 ± 8 years) scheduled for elective coronary angiography. A comprehensive clinical assessment included a carotid artery and abdominal ultrasound involving the following fat depots: (1) carotid extra-media thickness (EMT) indexed to the body mass index (perivascular adipose tissue [PVAT]), and (2) abdominal visceral and subcutaneous fat...
January 17, 2019: Journal of Diabetes and its Complications
https://read.qxmd.com/read/30763747/a-new-neuropathological-mechanism-of-blood-ph-irregularities-after-neck-trauma-importance-of-carotid-body-glossopharyngeal-nerve-network-degeneration
#4
Tayfun Çakır, Selim Kayacı, Mehmet Dumlu Aydın, Baris Özöner, İlknur Çalık, Konca Altınkaynak
No abstract text is available yet for this article.
February 11, 2019: World Neurosurgery
https://read.qxmd.com/read/30759365/exenatide-once-weekly-improves-metabolic-parameters-endothelial-dysfunction-and-carotid-intima-media-thickness-in-patients-with-type-2-diabetes-an-8-month-prospective-study
#5
Angelo Maria Patti, Dragana Nikolic, Antonio Magan-Fernandez, Rosaria Vincenza Giglio, Giuseppa Castellino, Roberta Chianetta, Roberto Citarrella, Egle Corrado, Francesca Provenzano, Vincenzo Provenzano, Giuseppe Montalto, Ali A Rizvi, Manfredi Rizzo
AIM: To evaluate the effect of exenatide long acting release (LAR) on carotid intima-media thickness (IMT) and endothelial function in patients with type 2 diabetes mellitus. METHODS: Sixty subjects with type 2 diabetes mellitus were treated with exenatide LAR as add-on to stable doses of metformin for 8 months in an open label study. Anthropometric variables, lipid profile and glycemic parameters were assessed by routine analysis. Carotid IMT by Doppler ultrasound and endothelial function by flow-mediated dilation of the brachial artery were also assessed...
February 10, 2019: Diabetes Research and Clinical Practice
https://read.qxmd.com/read/30744510/long-term-hemodynamic-effects-after-carotid-artery-revascularization
#6
Sungho Lim, Michael J Javorski, Sean P Nassoiy, Yaeji Park, Pegge M Halandras, Carlos F Bechara, Bernadette Aulivola, Paul R Crisostomo
OBJECTIVE: The baroreceptor at the carotid body plays an important role in hemodynamic autoregulation. Manipulation of the baroreceptor during carotid endarterectomy (CEA) or radial force from carotid artery angioplasty and/or stenting (CAS) may cause both intraoperative and postoperative hemodynamic instability. The purpose of this study is to evaluate the long-term effects of CEA and CAS on blood pressure (BP), heart rate (HR), and subsequent changes on antihypertensive medications...
February 11, 2019: Vascular and Endovascular Surgery
https://read.qxmd.com/read/30742355/high-burden-of-subclinical-cardiovascular-target-organ-damage-after-pediatric-liver-transplantation
#7
Nima Memaran, Bianca Borchert-Mörlins, Bernhard M W Schmidt, Rizky I Sugianto, Hannes Wilke, Ricarda Blöte, Ulrich Baumann, Elena Bauer, Anika von Wick, Norman Junge, Christoph Leiskau, Eva D Pfister, Daniela Thurn-Valsassina, Nicolas Richter, Imeke Goldschmidt, Anette Melk
Cardiovascular (CV) events account for 8% to 13% of deaths after liver transplantation (LT) in adulthood. Although CV risk factors are present, little is known about the prevalence of subclinical CV target organ damage in children after LT. The aim of this prospective observational study was to assess the prevalence of subclinical CV target organ damage in children after LT and to identify risk factors contributing to CV damage as potential targets for clinical intervention. In this study, 104 children after LT (54% female, 46% male, aged 11...
February 11, 2019: Liver Transplantation
https://read.qxmd.com/read/30735857/the-impact-of-sedentary-behavior-patterns-on-carotid-atherosclerotic-burden-implications-from-the-corinthia-epidemiological-study
#8
George Lazaros, Evangelos Oikonomou, Georgia Vogiatzi, Evangelia Christoforatou, Sotirios Tsalamandris, Athina Goliopoulou, Maria Tousouli, Vasiliki Mystakidou, Christos Chasikidis, Dimitris Tousoulis
BACKGROUND AND AIMS: Sedentary lifestyle, unlike leisure time physical activity (PA), is associated with atherosclerosis progression. Regarding the interrelationship between television watching, as a sedentary behavior pattern, and cardiovascular disease burden, few data exist. METHODS: In this cross-sectional epidemiological study based on 2043 inhabitants of the Corinthia region, in Greece, ultrasonography was used to measure carotid intima-media thickness (IMT) in both carotid arteries...
January 29, 2019: Atherosclerosis
https://read.qxmd.com/read/30718145/non-invasive-small-vessel-imaging-of-human-thyroid-using-motion-corrected-spatiotemporal-clutter-filtering
#9
Rohit Nayak, Viksit Kumar, Jeremy Webb, Mostafa Fatemi, Azra Alizad
Reliable assessment of small vessel blood flow in the thyroid, without using any contrast agents, can be challenging because of increased physiological motion resulting from its proximity to the pulsating carotid artery. In this study, we hypothesized that correction of tissue motion prior to singular value decomposition (SVD)-based clutter filtering can improve the coherency of the tissue components and, thus, may allow better clutter suppression and visualization of small vessels in the thyroid. We corroborated this hypothesis by conducting phantom and in vivo studies using a clinical ultrasound scanner implemented with compounded plane wave imaging...
February 2, 2019: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/30717569/noninvasive-assessment-of-subclinical-atherosclerosis-in-patients-with-rosacea
#10
Gülhan Gürel, Yaşar Turan
BACKGROUND: Rosacea is a chronic, inflammatory cutaneous disorder that is characterized by remissions and relapses that commonly occur in patients over the age of 30 years. There have been many studies in literature evaluating the relationship between cardiovascular disease and psoriasis, which is a chronic inflammatory disease, however, there have been very few studies to date evaluating the relationship between rosacea and cardiovascular disease risk. METHODS: The study included 52 consecutive rosacea patients and 52 healthy controls matched for age, gender and body mass index...
February 4, 2019: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://read.qxmd.com/read/30716076/greater-aortic-stiffness-is-associated-with-renal-dysfunction-in-participants-of-the-elsa-brasil-cohort-with-and-without-hypertension-and-diabetes
#11
Júlia S A Cândido, Lidyane V Camelo, José Geraldo Mill, Paulo A Lotufo, Antonio Luiz P Ribeiro, Bruce B Duncan, Luisa C C Brant, Sandhi Maria Barreto
BACKGROUND: Arterial stiffness has been associated with renal dysfunction and its progression, but the pathophysiological relation underlying this association has not been fully established, particularly among individuals without hypertension and diabetes. We investigated the cross-sectional associations between arterial stiffness and renal function in adults without cardiovascular disease, and whether this association remained among subjects without hypertension and diabetes. METHODS: All eligible participants from ELSA-Brasil (2008-2010), aged 35 to 74 years (N = 13,586) were included, of whom 7,979 were free from hypertension and diabetes...
2019: PloS One
https://read.qxmd.com/read/30713398/epicardial-adipose-tissue-predicts-carotid-intima-media-thickness-independently-of-body-mass-index-and-waist-circumference
#12
Turan Erdoğan, Murtaza Emre Durakoğlugil, Mustafa Çetin, Sinan Altan Kocaman, Hakan Duman, Yüksel Çiçek, Ömer Şatıroğlu
Background: Visceral obesity is strongly associated with atherosclerosis. Even though waist circumference (WC) is the most common assessment method of total visceral adipose tissue and cardiometabolic risk, this method lacks direct measurement of adipose tissue and has better correlation to subcutaneous fat rather than visceral fat. We intended to investigate whether epicardial adipose tissue (EAT) is clinically superior to body mass index (BMI) and WC in predicting Framingham risk score (FRS) and carotid intima-media thickness (CIMT)...
January 2019: Acta Cardiologica Sinica
https://read.qxmd.com/read/30707615/right-ventricular-remodeling-in-response-to-volume-overload-in-fetal-sheep
#13
Tara B Karamlou, George D Giraud, Donogh F McKeogh, Sonnet S Jonker, Irving Shen, Ross M Ungerlieder, Kent L Thornburg
The fetal myocardium is known to be sensitive to hemodynamic load, responding to systolic overload with cellular hypertrophy, proliferation and accelerated maturation. However, the fetal cardiac growth response to primary volume overload is unknown. We hypothesized that increased venous return would stimulate fetal cardiomyocyte proliferation and terminal differentiation, particularly in the right ventricle (RV). Sixteen late-gestation fetal sheep had vascular catheters and pulmonary artery flow probes implanted...
February 1, 2019: American Journal of Physiology. Heart and Circulatory Physiology
https://read.qxmd.com/read/30705740/subclinical-carotid-atherosclerosis-predicts-all-cause-mortality-and-cardiovascular-events-in-obese-patients-with-negative-exercise-echocardiography
#14
Rafael Vidal-Perez, Raúl Franco-Gutiérrez, Alberto J Pérez-Pérez, Virginia Franco-Gutiérrez, Alberto Gascón-Vázquez, Andrea López-López, Ana María Testa-Fernández, Carlos González-Juanatey
BACKGROUND: Obesity is a major health problem due to its high prevalence. The relationship between obesity and cardiovascular disease is unclear. Some studies agree that certain conditions associated with obesity, such as physical inactivity or cardiovascular risk factors, are responsible for cardiovascular risk excess among obese people. Carotid intima-media thickness and carotid plaques (CP) have been associated with cardiovascular adverse events in healthy populations, and recent data suggest a higher prevalence of subclinical carotid atherosclerosis in obese and metabolically unhealthy patients...
January 26, 2019: World Journal of Cardiology
https://read.qxmd.com/read/30704917/effects-of-sex-steroids-on-cardiovascular-risk-profile-in-transgender-men-under-gender-affirming-hormone-therapy
#15
Gloria Aranda, Mireia Mora, Felicia A Hanzu, Josep Vera, Emilio Ortega, Irene Halperin
PURPOSE: Gender affirming hormone therapy (HT) in transgender men both improves and impairs several surrogate cardiovascular risk markers. However, few prospective works with long follow-up and control group are available. In this context, this work aimed to assess the changes in the metabolic and cardiovascular risk pattern after 12 months of HT in transgender men. Furthermore, we aimed to investigate early effects on target tissues that may reflect an initial vascular damage. METHODS: Prospective observational study, including 20 transgender men, attended in the Gender Identity Unit (UIG) of the Hospital Clinic from July 2013 to November 2015...
January 28, 2019: Endocrinología, Diabetes y Nutrición
https://read.qxmd.com/read/30704382/relationship-of-remodeling-of-carotid-arteries-and-left-ventricular-geometry-in-patients-with-chronic-glomerulonephritis
#16
Ilchom T Murkamilov, K A Aitbaev, A Sh Sarybaev, V V Fomin, I G Gordeev, Z R Rayimzhanov, N A Redjapova, F A Yusupov
PURPOSE: to study clinical-functional features of remodeling of carotid arteries and its relation to restructuring of the left ventricle (LV) in patients with chronic glomerulonephritis at pre-dialysis stage. MATERIALS AND METHODS: We examined 269 patients (189 men, 80 women) with chronic glomerulonephritis (CGN) aged 17-71 years, at pre-dialysis stages of the disease. We analyzed biochemical parameters of peripheral blood with the determination of daily proteinuria and glomerular filtration rate (GFR)...
November 18, 2018: Kardiologiia
https://read.qxmd.com/read/30700294/comparative-effects-of-lipid-lowering-hypoglycemic-antihypertensive-and-antiplatelet-medications-on-carotid-artery-intima-media-thickness-progression-a-network-meta-analysis
#17
Rongzhong Huang, Kerry Mills, Julio Romero, Yan Li, Zicheng Hu, Yu Cao, Hua Huang, Yu Xu, Lihong Jiang
BACKGROUND: Carotid artery intima-media thickness (cIMT) progression is a surrogate marker of atherosclerosis with a high predictive value for future CVD risk. This study evaluates the comparative efficacies of lipid lowering, hypoglycemic, antihypertensive and antiplatelet medications on cIMT progression. METHODS: We conducted a network meta-analysis (NMA) to evaluate the relative efficacies of several drug classes in modifying cIMT progression. After a literature search in several electronic databases, studies were selected by following predetermined eligibility criteria...
January 30, 2019: Cardiovascular Diabetology
https://read.qxmd.com/read/30688191/left-and-right-ventricular-function-by-echocardiography-tissue-doppler-imaging-carotid-intima-media-thickness-and-asymmetric-dimethyl-arginine-levels-in-obese-adolescents-with-metabolic-syndrome
#18
Eyup Aslan, Ahmet Sert, Muammer Buyukinan, Mustafa Ozgur Pirgon, Huseyin Kurku, Hakan Yilmaz, Dursun Odabas
PurposeThe aim of our study was to assess left ventricle and right ventricle systolic and diastolic functions in obese adolescents with metabolic syndrome using conventional echocardiography and pulsed-wave tissue Doppler imaging and to investigate carotis intima-media thickness, and asymmetric dimethyl arginine levels. METHODS: A total of 198 obese adolescents were enrolled in the study. The obese patients were divided into metabolic syndrome group and non-metabolic syndrome group. All subjects underwent laboratory blood tests, including asymmetric dimethyl arginine, complete two-dimensional, pulsed, and tissue Doppler echocardiography, and measurement of the carotid intima-media thickness...
January 28, 2019: Cardiology in the Young
https://read.qxmd.com/read/30684613/-surgical-management-of-bilateral-carotid-body-tumors
#19
Luis O Bobadilla-Rosado, Ramon Garcia-Alva, Javier E Anaya-Ayala, Cynthia Peralta-Vazquez, Kemberly Hernandez-Sotelo, Lizeth Luna, Cesar Cuen-Ojeda, Carlos A Hinojosa
BACKGROUND: Carotid body tumors (CBTs) are rare neoplasms located in the carotid bifurcation. The majority of these tumors are unilateral; bilateral CBTs represent approximately 5% of all affected patients and the recommended treatment is to surgically remove them in staged-planned surgeries. We describe the experience, outcomes and the surgical management of bilateral CBTs in our institution. METHODS: A retrospective review of CBTs patients was completed; Patients demographics, comorbidities, lesion location, anatomic characteristics, surgical techniques, complications, reinterventions and other factors that may influence outcomes were evaluated...
January 23, 2019: Annals of Vascular Surgery
https://read.qxmd.com/read/30683821/controlled-aerobic-training-improves-endothelial-function-and-modifies-vascular-remodeling-in-healthy-adults-with-high-normal-blood-pressure
#20
J Glodzik, K Rewiuk, J Adamiak, J Marchewka, A Salakowski, M Mazur, J Brudecki, T P Mikolajczyk, T Guzik, P Aleksander-Szymanowicz, T Grodzicki
The aim of the study was to assess endothelial function in adults with high normal blood pressure (HNBP) undergoing controlled aerobic training. The study was conducted among 31 volunteers with HNBP. Subjects underwent supervised cycle ergometer training for 12 weeks. Exercise intensity was assessed by monitoring the pulse with intention to keep the heart rate increase within the range of 40% to 65% of the heart rate reserve. The control group consisted of 14 healthy adults, not subjected to any intervention...
October 2018: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
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