keyword
https://read.qxmd.com/read/38535565/wildlife-as-food-and-medicine-in-brazil-a-neglected-zoonotic-risk
#1
JOURNAL ARTICLE
Caio Graco Zeppelini, Ianei de Oliveira Carneiro, Poliana Mascarenhas de Abreu, Ann Katelynn Linder, Romulo Romeu Nóbrega Alves, Federico Costa
The practice of consuming wild fauna in Brazil is both culturally and socioeconomically questionable. Wild animals and their byproducts are sought for nutritional, medicinal, and/or supernatural reasons, with some taxa (e.g., songbirds) being kept as pets. This practice is concentrated in traditional and rural communities, as well as the rural exodus populations in large urban centers, maintained both by cultural preferences and for their role in food safety in part of the rural exodus community. A total of 564 taxa are known to be sold in wet markets in Brazil, with birds, fish, and mammals being the most commonly listed...
March 2, 2024: Pathogens
https://read.qxmd.com/read/38535090/machine-learning-identifies-higher-survival-profile-in-extracorporeal-cardiopulmonary-resuscitation
#2
JOURNAL ARTICLE
Ruben Crespo-Diaz, Julian Wolfson, Demetris Yannopoulos, Jason A Bartos
OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival in patients with refractory out-of-hospital cardiac arrest (OHCA) caused by shockable rhythms. Further refinement of patient selection is needed to focus this resource-intensive therapy on those patients likely to benefit. This study sought to create a selection model using machine learning (ML) tools for refractory cardiac arrest patients undergoing ECPR. DESIGN: Retrospective cohort study...
March 27, 2024: Critical Care Medicine
https://read.qxmd.com/read/38533294/a-review-and-discussion-of-full-time-equivalency-and-appropriate-compensation-models-for-an-adult-intensivist-in-the-united-states-across-various-base-specialties
#3
JOURNAL ARTICLE
Michael Nurok, Brigid C Flynn, Marc Pineton de Chambrun, Mina Kazemian, Joel Geiderman, Mark E Nunnally
OBJECTIVES: Physicians with training in anesthesiology, emergency medicine, internal medicine, neurology, and surgery may gain board certification in critical care medicine upon completion of fellowship training. These clinicians often only spend a portion of their work effort in the ICU. Other work efforts that benefit an ICU infrastructure, but do not provide billing opportunities, include education, research, and administrative duties. For employed or contracted physicians, there is no singular definition of what constitutes an intensive care full-time equivalent (FTE)...
April 2024: Critical care explorations
https://read.qxmd.com/read/38532738/depression-and-associated-risk-factors-among-emergency-medicine-interns-results-from-a-national-longitudinal-cohort-study
#4
JOURNAL ARTICLE
Destiny D Folk, Cortlyn Brown, Carrie C Bissell, Lauren A Fowler
OBJECTIVE: Despite depression being common in residents, there are no published studies on the prevalence and risk factors for depression in emergency medicine (EM) interns. Our objectives were to explore the prevalence of depression among EM interns and to identify risk factors for depression including sleep, work hours, rotation type, race, ethnicity, sex, and age. METHODS: The Intern Health Study is a national longitudinal cohort study on intern mental health in all specialties...
April 2024: AEM Education and Training
https://read.qxmd.com/read/38532263/diagnostic-and-prognostic-value-of-cardiac-troponins-in-emergency-department-patients-presenting-after-a-fall-a-prospective-multicenter-study
#5
JOURNAL ARTICLE
Tanguy Espejo, Lukas Terhalle, Alexandra Malinovska, Henk B Riedel, Laura Arntz, Livia Hafner, Karen Delport-Lehnen, Joanna Zuppinger, Nicolas Geigy, Jörg Leuppi, Rajan Somasundaram, Roland Bingisser, Christian H Nickel
BACKGROUND: Emergency department (ED) presentations after a ground-level fall (GLF) are common. Falls were suggested to be another possible presenting feature of a myocardial infarction (MI), as unrecognized MIs are common in older adults. Elevated high-sensitivity cardiac troponin (hs-cTn) concentrations could help determine the etiology of a GLF in ED. We investigated the prevalence of both MI and elevated high-sensitivity cardiac troponin T (hs-cTnT) and I (hs-cTnI), as well as the diagnostic accuracy of hs-cTnT and hs-cTnI regarding MI, and their prognostic value in older ED patients presenting after a GLF...
March 26, 2024: Academic Emergency Medicine
https://read.qxmd.com/read/38532048/awake-pronation-with-helmet-cpap-in-early-covid-19-ards-patients-effects-on-respiratory-effort-and-distribution-of-ventilation-assessed-by-eit
#6
JOURNAL ARTICLE
Tommaso Fossali, Martina Locatelli, Riccardo Colombo, Alice Veronese, Beatrice Borghi, Elisabetta Ballone, Antonio Castelli, Roberto Rech, Emanuele Catena, Davide Ottolina
Prone positioning with continuous positive airway pressure (CPAP) is widely used for respiratory support in awake patients with COVID-19-associated acute respiratory failure. We aimed to assess the respiratory mechanics and distribution of ventilation in COVID-19-associated ARDS treated by CPAP in awake prone position. We studied 16 awake COVID-19 patients with moderate-to-severe ARDS. The study protocol consisted of a randomized sequence of supine and prone position with imposed positive end-expiratory pressure (PEEP) of 5 and 10 cmH2 O delivered by helmet CPAP...
March 26, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38532047/peripherally-inserted-central-catheter-fracture-and-migration
#7
JOURNAL ARTICLE
Huajin Liu, Ya Qiu, Guojie Wang
No abstract text is available yet for this article.
March 26, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38530078/validation-of-adult-sepsis-event-and-epidemiologic-analysis-of-sepsis-prevalence-and-mortality-using-adult-sepsis-event-s-electronic-health-records-based-sequential-organ-failure-assessment-criteria-a-single-center-study-in-south-korea
#8
JOURNAL ARTICLE
Su Yeon Lee, Mi Hyeon Park, Dong Kyu Oh, Chae-Man Lim
OBJECTIVES: In 2018, the Centers for Disease Control and Prevention introduced the Adult Sepsis Event (ASE) definition, using electronic health records (EHRs) data for surveillance and sepsis quality improvement. However, data regarding ASE outside the United States remain limited. We therefore aimed to validate the diagnostic accuracy of the ASE and to assess the prevalence and mortality of sepsis using ASE. DESIGN: Retrospective cohort study. SETTING: A single center in South Korea, with 2732 beds including 221 ICU beds...
March 26, 2024: Critical Care Medicine
https://read.qxmd.com/read/38529607/gene-therapy-for-skin-aging
#9
JOURNAL ARTICLE
Fawzy A Saad
Extrinsic and intrinsic factors contribute to skin aging; nonetheless, they are intertwined. Moreover, intrinsic skin aging mirrors age-related declines in the entire human body's internal organs. There is evidence that skin appearance is an indicator of the general health of somebody. Earlier, it was apparent that the intrinsic factors are unalterable, but the sparkling of skin aging gene therapy on the horizon is changing this narrative. Skin aging gene therapy offers tools for skin rejuvenation and, natural beauty restoration, and therapy for diseases affecting the entire skin...
March 25, 2024: Current Gene Therapy
https://read.qxmd.com/read/38529478/network-pharmacology-and-experimental-verification-reveal-the-regulatory-mechanism-of-chuanbeimu-in-treating-chronic-obstructive-pulmonary-disease
#10
JOURNAL ARTICLE
Meilan Xian, Jiaoyuan Xu, Yamei Zheng, Lei Zhang, Jie Zhao, Jie Chen, Siguang Li, Lingsang Lin, Yi Zhong, Zehua Yang, Tian Xie, Linhui Huang, Yipeng Ding
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a common respiratory disorder in pulmonology. Chuanbeimu (CBM) is a traditional Chinese medicinal herb for treating COPD and has been widely utilized in clinical practice. However, the mechanism of CBM in the treatment of COPD remains incompletely understood. This study aims to investigate the underlying therapeutic mechanism of CBM for COPD using network pharmacology and experimental approaches. METHODS: Active ingredients and their targets were obtained from the Traditional Chinese Medicine Systems Pharmacology database...
2024: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/38528974/world-addiction-medicine-reports-formation-of-the-international-society-of-addiction-medicine-global-expert-network-isam-gen-and-its-global-surveys
#11
JOURNAL ARTICLE
Hamed Ekhtiari, Arash Khojasteh Zonoozi, Parnian Rafei, Fateme Sadat Abolghasemi, Dan Pemstein, Tarek Abdelgawad, Sophia Achab, Hamad Al Ghafri, Mustafa Al'Absi, Michaël Bisch, Aldo Alberto Conti, Atul Ambekar, Shalini Arunogiri, Roshan Bhad, Rabia Bilici, Kathleen Brady, Gregory Bunt, Anja Busse, Jenna L Butner, Ahmad Danesh, Joseph El-Khoury, Fatima El Omari, Darius Jokūbonis, Cor de Jong, Geert Dom, Mohsen Ebrahimi, Ali Fathi Jouzdani, Marica Ferri, Susanna Galea-Singer, Dario Gigena Parker, Susumu Higuchi, Preethy Kathiresan, Emira Khelifa, Christos Kouimtsidis, Evgeny M Krupitsky, Jiang Long, Icro Maremmani, Garrett McGovern, Hossein Mohaddes Ardabili, Afarin Rahimi-Movaghar, Solomon Tshimong Rataemane, Arshiya Sangchooli, Goodman Sibeko, Anna Maria Vella, Salvador Benjamin D Vista, Mehran Zare-Bidoky, Min Zhao, Afzal Javed, Marc N Potenza, Alexander Mario Baldacchino
Addiction medicine is a dynamic field that encompasses clinical practice and research in the context of societal, economic, and cultural factors at the local, national, regional, and global levels. This field has evolved profoundly during the past decades in terms of scopes and activities with the contribution of addiction medicine scientists and professionals globally. The dynamic nature of drug addiction at the global level has resulted in a crucial need for developing an international collaborative network of addiction societies, treatment programs and experts to monitor emerging national, regional, and global concerns...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38528234/editorial-time-to-treat-the-climate-and-nature-crisis-as-one-indivisible-global-health-emergency
#12
EDITORIAL
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
No abstract text is available yet for this article.
March 25, 2024: Journal of General Internal Medicine
https://read.qxmd.com/read/38528127/3d-bioprinting-based-dopamine-coupled-flexible-material-for-nasal-cartilage-repair
#13
JOURNAL ARTICLE
Wendan Jia, Zixian Liu, Zhuwei Ma, Peiyi Hou, Yanyan Cao, Zhizhong Shen, Meng Li, Hulin Zhang, Xing Guo, Shengbo Sang
INTRODUCTION: Since 3D printing can be used to design implants according to the specific conditions of patients, it has become an emerging technology in tissue engineering and regenerative medicine. How to improve the mechanical, elastic and adhesion properties of 3D-printed photocrosslinked hydrogels is the focus of cartilage tissue repair and reconstruction research. MATERIALS AND METHODS: We established a strategy for toughening hydrogels by mixing GelMA-DOPA (GD), which is prepared by coupling dopamine (DA) with GelMA, with HAMA, bacterial cellulose (BC) to produce composite hydrogels (HB-GD)...
March 25, 2024: Aesthetic Plastic Surgery
https://read.qxmd.com/read/38528053/secondary-use-of-genomic-data-patients-decisions-at-point-of-testing-and-perspectives-to-inform-international-data-sharing
#14
JOURNAL ARTICLE
Melissa Martyn, Emily Forbes, Ling Lee, Anaita Kanga-Parabia, Rona Weerasuriya, Elly Lynch, Penny Gleeson, Clara Gaff
International sharing of genomic data files arising from clinical testing of patients is essential to further improve genomic medicine. Whilst the general public are reluctant to donate DNA for research, the choices patients actually make about sharing their clinical genomic data for future re-use (research or clinical) are unknown. We ascertained the data-sharing choices of 1515 patients having genomic testing for inherited conditions or cancer treatment from clinical consent forms. To understand the experiences and preferences of these patients, surveys were administered after test consent (RR 73%)...
March 25, 2024: European Journal of Human Genetics: EJHG
https://read.qxmd.com/read/38527482/outcomes-after-surgery-for-children-in-africa-asos-paeds-a-14-day-prospective-observational-cohort-study
#15
JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: Safe anaesthesia and surgery are a public health imperative. There are few data describing outcomes for children undergoing anaesthesia and surgery in Africa. We aimed to get robust epidemiological data to describe patient care and outcomes for children undergoing anaesthesia and surgery in hospitals in Africa. METHODS: This study was a 14-day, international, prospective, observational cohort study of children (aged <18 years) undergoing surgery in Africa...
March 22, 2024: Lancet
https://read.qxmd.com/read/38527480/a-legal-mapping-of-48-who-member-states-inclusion-of-public-health-emergency-of-international-concern-pandemic-and-health-emergency-terminology-within-national-emergency-legislation-in-responding-to-health-emergencies
#16
REVIEW
Clare Wenham, Liam Stout
WHO has determined a public health emergency of international concern (PHEIC) seven times, and beyond this nomenclature declared COVID-19 to be a pandemic. Under the International Health Regulations (IHR), and through their operationalisation in the joint external evaluation (JEE), governments are urged to create suitable legislation to be able to enact a response to a public health emergency. Whether the pandemic declaration had a greater effect than a PHEIC in encouraging goverments to act, however, remains conjecture, as there is no systemic analysis of what each term means in practice and whether either has meaningful legal implications at the national level...
March 22, 2024: Lancet
https://read.qxmd.com/read/38527444/the-emerging-role-of-ai-in-patient-education-a-comparative-analysis-of-llm-accuracy-for-pelvic-organ-prolapse
#17
JOURNAL ARTICLE
Sakine Rahimli Ocakoglu, Burhan Coskun
OBJECTIVE: This study aimed to evaluate the accuracy, completeness, precision, and readability of outputs generated by three Large Language Models (LLMs): GPT by OpenAI, BARD by Google, and Bing by Microsoft, in comparison to patient education material on Pelvic Organ Prolapse (POP) provided by the Royal College of Obstetricians and Gynecologists (RCOG). METHODS: A total of 15 questions were retrieved from the RCOG website and input into the three LLMs. Two independent reviewers evaluated the outputs for accuracy, completeness, and precision...
March 25, 2024: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/38527289/evaluation-of-strategies-for-transitioning-to-annual-sars-cov-2-vaccination-campaigns-in-the-united-states
#18
JOURNAL ARTICLE
Chad R Wells, Abhishek Pandey, Seyed M Moghadas, Meagan C Fitzpatrick, Burton H Singer, Alison P Galvani
BACKGROUND: The U.S. Food and Drug Administration has proposed administering annual SARS-CoV-2 vaccines. OBJECTIVE: To evaluate the effectiveness of an annual SARS-CoV-2 vaccination campaign, quantify the health and economic benefits of a second dose provided to children younger than 2 years and adults aged 50 years or older, and optimize the timing of a second dose. DESIGN: An age-structured dynamic transmission model. SETTING: United States...
March 26, 2024: Annals of Internal Medicine
https://read.qxmd.com/read/38526922/an-update-of-a-clinical-practice-guideline-for-the-management-of-patients-with-acute-spinal-cord-injury-recommendations-on-the-role-and-timing-of-decompressive-surgery
#19
JOURNAL ARTICLE
Michael G Fehlings, Lindsay A Tetreault, Laureen Hachem, Nathan Evaniew, Mario Ganau, Stephen L McKenna, Chris J Neal, Narihito Nagoshi, Vafa Rahimi-Movaghar, Bizhan Aarabi, Christoph P Hofstetter, Valerie Ter Wengel, Hiroaki Nakashima, Allan R Martin, Steven Kirshblum, Ricardo Rodrigues Pinto, Rex A W Marco, Jefferson R Wilson, David E Kahn, Virginia F J Newcombe, Carl M Zipser, Sam Douglas, Shekar N Kurpad, Yi Lu, Rajiv Saigal, Uzma Samadani, Paul M Arnold, Gregory W J Hawryluk, Andrea C Skelly, Brian K Kwon
STUDY DESIGN: Clinical practice guideline development. OBJECTIVES: Acute spinal cord injury (SCI) can result in devastating motor, sensory, and autonomic impairment; loss of independence; and reduced quality of life. Preclinical evidence suggests that early decompression of the spinal cord may help to limit secondary injury, reduce damage to the neural tissue, and improve functional outcomes. Emerging evidence indicates that "early" surgical decompression completed within 24 hours of injury also improves neurological recovery in patients with acute SCI...
March 2024: Global Spine Journal
https://read.qxmd.com/read/38526476/inappropriate-diagnosis-of-pneumonia-among-hospitalized-adults
#20
JOURNAL ARTICLE
Ashwin B Gupta, Scott A Flanders, Lindsay A Petty, Tejal N Gandhi, Michael S Pulia, Jennifer K Horowitz, David Ratz, Steven J Bernstein, Anurag N Malani, Payal K Patel, Timothy P Hofer, Tanima Basu, Vineet Chopra, Valerie M Vaughn
IMPORTANCE: Little is known about incidence of, risk factors for, and harms associated with inappropriate diagnosis of community-acquired pneumonia (CAP). OBJECTIVE: To characterize inappropriate diagnosis of CAP in hospitalized patients. DESIGN, SETTING, AND PARTICIPANTS: This prospective cohort study, including medical record review and patient telephone calls, took place across 48 Michigan hospitals. Trained abstractors retrospectively assessed hospitalized patients treated for CAP between July 1, 2017, and March 31, 2020...
March 25, 2024: JAMA Internal Medicine
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