Yusuke Takaoka, Shunsuke Fujibayashi, Hirotaka Onoe, Koji Goto, Bungo Otsuki, Toshiyuki Kawai, Yaichiro Okuzu, Takayoshi Shimizu, Norimasa Ikeda, Kazuki Orita, Shintaro Honda, Tatsuhito Ikezaki, Takeshi Yabutsuka, Shuichi Matsuda
Porous structures are frequently used in surgical implants to strengthen the interlocking power produced by bone ingrowth. Therefore, we aimed to elucidate the mechanism underlying bone ingrowth into a porous structure accompanied by vascularization. A nonbioactive polyetheretherketone implant with a 3D-printed porous structure was prepared and implanted in a bone hole created in the tibias of rabbits. We observed bone ingrowth in the same individual specimens immediately and at 2, 4, 8, and 12 weeks post-implantation using in-vivo computed tomography (CT)...
February 15, 2024: Acta Biomaterialia