keyword
https://read.qxmd.com/read/33099855/erector-spinae-plane-block-vs-non-steroidal-anti-inflammatory-drugs-for-severe-renal-colic-pain-a-pilot-clinical-feasibility-study
#21
RANDOMIZED CONTROLLED TRIAL
Muhammed Enes Aydin, Erdal Tekin, Elif Oral Ahiskalioglu, Irem Ates, Selahattin Karagoz, Omerul Faruk Aydin, Fatih Ozkaya, Ali Ahiskalioglu
AIM: Ultrasound-guided plane blocks are increasingly used in the multi-modal analgesic concept for reducing opioid consumption. The present study was conducted to compare the analgesic effect of intravenous non-steroidal anti-inflammatory drugs (NSAIDs) and erector spinae plane (ESP) block in renal colic patients. METHODS: In this prospective randomised study, 40 patients with renal colic pain were randomly assigned into two groups: Group NSAID (n = 20) received an intravenous infusion of 50 mg of dexketoprofen trometamol and Group ESP (n = 20) received ultrasound-guided ESP block with 30 ml 0...
March 2021: International Journal of Clinical Practice
https://read.qxmd.com/read/33014084/the-use-of-multimodal-low-opioid-anesthesia-for-coronary-artery-bypass-grafting-surgery-in-conditions-of-artificial-blood-circulation
#22
JOURNAL ARTICLE
Oleg Loskutov, Taisiia Danchyna, Dmitryi Dzuba, Oleksandr Druzina
INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of death worldwide, and according to experts, they will continue to dominate the structure of global mortality. AIM: The effectiveness of the multimodal low-opioid anesthesia technique in performing coronary artery bypass graft operations with artificial blood circulation. MATERIAL AND METHODS: Ninety-six patients aged 61.8 ±10.4 years underwent coronary artery bypass grafting under artificial blood circulation...
September 2020: Polish Journal of Cardio-Thoracic Surgery
https://read.qxmd.com/read/32803439/comparison-of-the-effect-of-therapeutic-elastic-bandage-submucosal-dexamethasone-or-dexketoprofen-trometamol-on-inflammatory-symptoms-and-quality-of-life-following-third-molar-surgery-a-randomized-clinical-trial
#23
RANDOMIZED CONTROLLED TRIAL
Aras Erdil, Nihat Akbulut, Ahmet Altan, Mustafa Sami Demirsoy
OBJECTIVES: We aimed to compare the effects of preoperative single-dose submucosal corticosteroid injection and postoperative elastic therapeutic bandage application with postoperative non-steroid anti-inflammatory drug therapy on postoperative inflammatory symptoms and quality of life following mandibular third molar surgeries. MATERIALS AND METHODS: A single-center, randomized, clinical trial was conducted with 52 patients (36 female, 16 male) who expected severe postoperative sequelae as a result of the extraction of impacted mandibular third molars...
April 2021: Clinical Oral Investigations
https://read.qxmd.com/read/32359776/intravenous-metoclopramide-versus-dexketoprofen-trometamol-versus-metoclopramide-dexketoprofen-trometamol-in-acute-migraine-attack-in-the-emergency-department-a-randomized-double-blind-controlled-trial
#24
RANDOMIZED CONTROLLED TRIAL
E Yavuz, U Gulacti, U Lok, K Turgut
STUDY OBJECTIVE: The objective of this study was to determine the analgesic efficacy and safety of intravenous, single-dose metoclopramide versus dexketoprofen trometamol versus metoclopramide+ dexketoprofen trometamol in patients presenting with acute migraine attack to the emergency department (ED). METHODS: This single-center, randomized, double-blind study was conducted in a tertiary care ED. Eligible patients met the migraine criteria of the International Headache Society were randomized to receive 10 mg intravenous metoclopramide, 50 mg intravenous dexketoprofen trometamol, or 50 mg dexketoprofen trometamol +10 mg metoclopramide...
November 2020: American Journal of Emergency Medicine
https://read.qxmd.com/read/32079739/evaluation-of-ultrasound-guided-rhomboid-intercostal-nerve-block-for-postoperative-analgesia-in-breast-cancer-surgery-a-prospective-randomized-controlled-trial
#25
RANDOMIZED CONTROLLED TRIAL
Başak Altıparmak, Melike Korkmaz Toker, Ali Ihsan Uysal, Özcan Dere, Bakiye Uğur
BACKGROUND AND OBJECTIVES: Mastectomy has many potential sources of pain. Rhomboid intercostal block (RIB) is a recently described plane block. The primary hypothesis of the study is that ultrasound-guided RIB combined with general anesthesia would accelerate global quality of recovery scores of patients following mastectomy surgery. Secondary hypothesis is that RIB would reduce postoperative opioid consumption, pain scores, and the need for rescue analgesia. METHODS: Patients aged between 18 and 70 years, with American Society of Anesthesiologists physical status I-II and scheduled for an elective unilateral modified radical mastectomy surgery with axillary lymph node dissection were enrolled to the study...
April 2020: Regional Anesthesia and Pain Medicine
https://read.qxmd.com/read/31980886/postoperative-analgesic-efficacy-of-perioperative-intravenous-lidocaine-infusion-in-patients-undergoing-septorhinoplasty-a-prospective-randomized-double-blind-study
#26
RANDOMIZED CONTROLLED TRIAL
İrem Ates, Muhammed Enes Aydin, Ali Ahiskalioglu, Elif Oral Ahiskalioglu, Zulkuf Kaya, Mustafa Sitki Gozeler
PURPOSE: Intravenous lidocaine infusion has been used for postoperative analgesia in many surgical procedures in recent years. The aim of this randomized, double-blind study was to investigate the postoperative analgesic efficacy of perioperative intravenous lidocaine infusion in patients undergoing septorhinoplasty surgery. MATERIALS AND METHODS: Forty-eight American Society of Anesthesiologists I and II patients, aged 18-40 years scheduled for septorhinoplasty surgery, were assigned into two groups...
April 2020: European Archives of Oto-rhino-laryngology
https://read.qxmd.com/read/31798852/physicochemical-stability-of-binary-admixtures-of-paracetamol-and-dexketoprofen-trometamol-for-patient-controlled-analgesia-use
#27
JOURNAL ARTICLE
Alfonso Ángel López Navarro, María Amparo Martínez Gómez, Elena Gras Colomer, Pilar Campillos, Mónica Climente Martí
BACKGROUND: Intravenous admixtures of dexketoprofen-trometamol and paracetamol are frequently used in clinical practice due to synergism obtained administering both drugs concomitantly. Physicochemical stability of binary admixture containing both drugs is currently unknown. OBJECTIVE: To determine physicochemical stability of binary admixture containing dexketoprofen-trometamol 50 mg and paracetamol 1000 mg in a low-density polyethylene bottle at different storage conditions of light and temperature for advanced preparation...
November 2019: European Journal of Hospital Pharmacy. Science and Practice
https://read.qxmd.com/read/31758946/treatment-of-oxidative-stress-induced-pain-and-inflammation-with-dexketoprofen-trometamol-loaded-different-molecular-weight-chitosan-nanoparticles-formulation-characterization-and-anti-inflammatory-activity-by-using-in-vivo-het-cam-assay
#28
JOURNAL ARTICLE
A Alper Öztürk, H Tuba Kıyan
Angiogenesis is a fundamental process of wound healing, embryogenesis etc. but occurs in cancer and chronic inflammation pathologically. HET-CAM assay is a useful, well established and animal alternative test to screen anti-inflammatory potentials of pharmaceutical products as well as nano-formulations. Dexketoprofen trometamol (DT) belongs to the nonsteroidal anti-inflammatory drug (NSAID) group which is a rapidly acting analgesic ingredient. Because DT has a short half-life, high and frequent dosing is used in treatment...
November 20, 2019: Microvascular Research
https://read.qxmd.com/read/31741068/preemptive-analgesic-efficacy-of-the-ultrasound-guided-bilateral-superficial-serratus-plane-block-on-postoperative-pain-in-breast-reduction-surgery-a-prospective-randomized-controlled-study
#29
RANDOMIZED CONTROLLED TRIAL
Ali Ahiskalioglu, Ahmet Murat Yayik, Ufuk Demir, Elif Oral Ahiskalioglu, Erkan Cem Celik, Mursel Ekinci, Mine Celik, Hakan Cinal, Onder Tan, Muhammed Enes Aydin
PURPOSE: Breast surgery is an exceedingly common procedure and associated with an increased incidence of acute and chronic pain. Preemptive regional anesthesia techniques may improve postoperative analgesia for patients undergoing breast surgery. The aim of this study was to evaluate the effect of preoperative bilateral serratus plane block on postoperative opioid consumption in patients undergoing breast reduction surgery. METHODS: After ethical board approval, 40 patients undergoing breast reduction surgery were randomized into 2 groups: control group (Group C, n = 20) and serratus plane block group (Group SPB, n = 20)...
February 2020: Aesthetic Plastic Surgery
https://read.qxmd.com/read/31418598/combined-site-specific-release-retardant-mini-matrix-tablets-c-ssrrmt-for-extended-oral-delivery-of-dexketoprofen-trometamol-in-vitro-evaluation-and-single-versus-multiple-doses-pharmacokinetic-study-in-human-volunteers
#30
RANDOMIZED CONTROLLED TRIAL
Nabila M Sweed, Emad B Basalious, Samia A Nour
Development of extended release oral formulations of dexketoprofen trometamol (DT), a rapidly eliminated drug with high solubility, poses a great challenge especially when a portion of the dose is to be absorbed from the colon. In this study, site-specific release-retardant mini-matrix tablets (SSRRMTs) were developed and functionally coated with pH-responsive materials to achieve a site-specific delivery of DT at the duodenojejunal (DSRRMT) and ileocecal (ISRRMT) regions. Stomach-specific coated mini-tablets (SSCMTs) were manufactured for immediate release of about 16% of the daily dose of DT in the stomach...
November 2019: Drug Development and Industrial Pharmacy
https://read.qxmd.com/read/31133146/effect-of-dexketoprofene-trometamol-on-post-endoscopic-retrograde-cholangiopancreatography-pancreatitis
#31
JOURNAL ARTICLE
Aziz Ari, Bunyamin Gurbulak, Hasan Okmen, Cihad Tatar, Ufuk Oguz Idiz, Muhammed Zubeyr Ucuncu
OBJECTIVE: To evaluate the efficacy of dexketoprofene trometamol solution following the administration of contrast agent for Endoscopic Retrograde Cholangiopancreatography (ERCP) in decreasing the rate of pancreatitis, in experimental rat model. STUDY DESIGN: Experimental study. PLACE AND DURATION OF STUDY: Faculty of Medicine, Research and Animal Laboratory of Bezmialem University, Istanbul, Turkey in January 2018. METHODOLOGY: Forty Wistar-Albino® male rats of 250-300g were divided into 4 equal groups...
June 2019: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://read.qxmd.com/read/31072608/-ultrasound-guided-erector-spinae-plane-block-for-postoperative-analgesia-after-augmentation-mammoplasty-case-series
#32
JOURNAL ARTICLE
Başak Altıparmak, Melike Korkmaz Toker, Ali İhsan Uysal, Semra Gümüş Demirbilek
Augmentation mammoplasty is the third most frequently performed esthetic surgical procedure worldwide. Breast augmentation with prosthetic implants requires the insertion of an implant under breast tissue, which causes severe pain due to tissue extension and surgical trauma to separated tissues. In this case series, we present the successful pain management of six patients with ultrasound-guided Erector Spinae Plane block after augmentation mammoplasty. In the operating room, all patients received standard monitoring...
May 6, 2019: Revista Brasileira de Anestesiologia
https://read.qxmd.com/read/30901500/efficacy-of-targeted-liposomes-and-nanocochleates-containing-imatinib-plus-dexketoprofen-against-fibrosarcoma
#33
JOURNAL ARTICLE
Özlem Çoban, Zelihagül Değim, Şükran Yılmaz, Levent Altıntaş, Taibe Arsoy, Mahmut Sözmen
The main challenges in treating cancer using chemotherapeutics are insufficient dose at the target site and the development of drug resistance, while higher doses can induce side effects by damaging nontarget tissues. Combinatorial drug therapy may overcome these limitations by permitting lower doses and more specific targeting, thereby mitigating drug resistance and nontarget side effects. Recent reports indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) have anticancer potential and can be used together with conventional chemotherapeutics to improve efficacy and safety...
March 22, 2019: Drug Development Research
https://read.qxmd.com/read/30884755/exploring-bioequivalence-of-dexketoprofen-trometamol-drug-products-with-the-gastrointestinal-simulator-gis-and-precipitation-pathways-analyses
#34
JOURNAL ARTICLE
Marival Bermejo, Gislaine Kuminek, Jozef Al-Gousous, Alejandro Ruiz-Picazo, Yasuhiro Tsume, Alfredo Garcia-Arieta, Isabel González-Alvarez, Bart Hens, Gregory E Amidon, Nair Rodriguez-Hornedo, Gordon L Amidon, Deanna Mudie
The present work aimed to explain the differences in oral performance in fasted humans who were categorized into groups based on the three different drug product formulations of dexketoprofen trometamol (DKT) salt-Using a combination of in vitro techniques and pharmacokinetic analysis. The non-bioequivalence (non-BE) tablet group achieved higher plasma Cmax and area under the curve (AUC) than the reference and BE tablets groups, with only one difference in tablet composition, which was the presence of calcium monohydrogen phosphate, an alkalinizing excipient, in the tablet core of the non-BE formulation...
March 15, 2019: Pharmaceutics
https://read.qxmd.com/read/30573719/evaluation-of-the-analgesic-efficacies-of-dexketoprofen-trometamol-and-dexketoprofen-trometamol-thiocolchicoside-combinations-in-the-impacted-third-molar-surgery-randomised-clinical-trial
#35
JOURNAL ARTICLE
L Cigerim, V Kaplan
BACKGROUND: Postoperative pain is one of the most common complications. The aim of this study is to evaluate the analgesic efficacies of dexketoprofen trometamol and two different dosages of dexketoprofen trometamol + thiocolchicoside combination in the impacted third molar tooth operation. MATERIAL AND METHODS: This randomized, double-blind study included 75 patients who did not have any disease. Patients were assigned to 3 groups. Group 1 received 25 mg dexketoprofen trometamol + 4 mg thiocholchicoside, Group 2 received 25 mg dexketoprofen trometamol +8 mg thiocholchicoside, and Group 3 received 25 mg dexketoprofen trometamol...
January 1, 2019: Medicina Oral, Patología Oral y Cirugía Bucal
https://read.qxmd.com/read/30052082/an-in-vitro-investigation-of-genotoxic-effects-of-dexketoprofen-trometamol-on-healthy-human-lymphocytes
#36
JOURNAL ARTICLE
Merve Kılıc, Berrin Ayaz Tuylu
Non-steroidal anti-inflammatory drugs are drugs with analgesic, antipyretic, and anti-inflammatory effects. This study uses in vitro methods to investigate the potential and unknown genotoxic effects of dexketoprofen trometamol, an active substance in painkillers, on healthy human lymphocytes. In this study, a cytokinesis-block micronucleus cytome assay is used to investigate potential clastogenic, aneugenic activity and to identify chromosome breakages caused by the active drug substance dexketoprofen trometamol; a comet assay is performed to identify the genotoxic damage resulting from DNA single-strand breaks; a real-time reverse transcription polymerase chain reaction panel system is used to evaluate the potential negative effects on the expression of the genes responsible for DNA damage assessment...
July 27, 2018: Drug and Chemical Toxicology
https://read.qxmd.com/read/30034413/comparison-of-the-effects-of-intravenous-dexketoprofen-trometamol-versus-paracetamol-on-postoperative-analgesia-in-patients-undergoing-septoplasty-a-randomised-double-blind-clinical-trial
#37
JOURNAL ARTICLE
Caliskan E, Sener M, Kipri M, Yilmaz I, Aribogan A
BACKGROUND AND OBJECTIVE: Septoplasty operations are associated with moderate to severe postoperative pain which has unfavourable effects on patient's recovery and postoperative outcome. The aim of this study was to compare effects of intravenous paracetamol and dexketoprofen on postoperative analgesia, tramadol consumption and side effects after septoplasty. METHODS: In total 72 patients (aged 18-65 years) who had undergone an elective septoplasty from August 2013 to January 2015 in Baskent University Faculty of Medicine, in the Department of Anesthesiology and Reanimation Clinics were included in this study...
May 2018: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/29569951/a-review-of-dexketoprofen-trometamol-in-acute-pain
#38
REVIEW
Magdi Hanna, Jee Y Moon
OBJECTIVE: Dexketoprofen trometamol is a modified non-selective COX inhibitor with a rapid onset of action that is available as both oral and parenteral formulations. The aim of this narrative review was to assess the efficacy and tolerability/safety of dexketoprofen trometamol in acute pain states using the best available published scientific evidence (randomized controlled clinical trials and systematic reviews/meta-analyses). METHODS: Literature retrieval was performed via Medline, Embase and the Cochrane Library (from inception up to March 2017) using combinations of the terms "randomized controlled trials", "dexketoprofen", "celecoxib", "etoricoxib", "parecoxib" and "acute pain"...
February 2019: Current Medical Research and Opinion
https://read.qxmd.com/read/29485557/closure-of-oroantral-communication-with-plasma-rich-fibrin-membrane
#39
JOURNAL ARTICLE
Umut Demetoglu, Hakan Ocak, Suheyb Bilge
Oroantral communication (OAC) is the opening between the maxillary sinus and oral cavity. It may cause oroantral fistula or maxillary sinusitis if left untreated. The surgical closure of the OAC within 48 hours was recommended to avoid the complications like sinus infections. The aim of this study is to evaluate the treatment of OACs with plasma-rich fibrin (PRF) which is safe and easy to implement in the OACs.This study was conducted with the patients, who required the treatment of the OAC, which was developed after the posterior maxillary tooth extraction in the Dental and Maxillofacial Department of the Faculty of Dentistry in Adnan Menderes University...
June 2018: Journal of Craniofacial Surgery
https://read.qxmd.com/read/29356603/effects-of-the-preoperative-administration-of-dexketoprofen-trometamol-on-pain-and-swelling-after-implant-surgery-a-randomized-double-blind-controlled-trial
#40
RANDOMIZED CONTROLLED TRIAL
Arturo Sánchez-Pérez, Jesús Muñoz-Peñalver, María José Moya-Villaescusa, Carmen Sánchez-Matás
The fear of postoperative pain is often mentioned by patients as one of the factors that is most frequently associated with dental implants. To reduce this factor, a single oral dose of 25 mg dexketoprofen trometamol (DKT) or placebo was administered 15 minutes before implant surgery. One hundred patients who required single-implant treatments were randomly assigned to 1 of 2 blinded groups. The patients in the test group were given 25 mg DKT (DKT group), and those in the control group were given 500 mg vitamin C as a placebo (PLACEBO group)...
April 2018: Journal of Oral Implantology
keyword
keyword
162578
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.