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Camilo Andrés Chaparro, Santiago Bernal-Macías, Oscar Mauricio Muñoz
Lupus enteritis denotes inflammation of the intestinal walls resulting from the influence of systemic lupus erythematosus. It represents a rare manifestation associated with notable morbidity and mortality, marked by nonspecific gastrointestinal symptoms. In this article, we present two cases of individuals experiencing severe gastrointestinal symptoms. They had a personal or familial history of autoimmunity with intestinal involvement consistent with the presentation of lupus enteritis. Following treatment with glucocorticoids and immunomodulators, both patients exhibited a satisfactory clinical evolution...
2024: SAGE Open Medical Case Reports
#2
JOURNAL ARTICLE
Laura Weber, Alfredo Torres, Ornella Realini, María José Bendek, María Luisa Mizgier, Claudia Brizuela, David Herrera, Fermín E González, Alejandra Chaparro
Despite the understanding of the coronavirus disease-19 (COVID-19), the role of salivary extracellular vesicles (sEVs) in COVID-19 remains unclear. Exploring the proteomic cargo of sEVs could prove valuable for diagnostic and prognostic purposes in assessing COVID-19. The proteomic cargo of sEVs from COVID-19(+) subjects and their healthy close contacts (HCC) was explored. sEVs were isolated by ultracentrifugation from unstimulated saliva samples, and subsequently characterized through nanoparticle tracking, transmission electron microscopy, and Western blot analyses...
March 26, 2024: International Journal of Molecular Sciences
#3
REVIEW
Noelia Lucía Martínez-Rives, María Del Pilar Martín Chaparro, Bibha Dhungel, Stuart Gilmour, Rory D Colman, Yasuhiro Kotera
(1) Background: This systematic review presents an overview of psychological interventions in suicide published between 2013 and 2023 in Spain and Japan, sparked by Spain's alarming recent increase in suicide rates and the potential exemplar of Japan's reduction efforts. (2) Methods: Following the PRISMA checklist, the databases Web of Science, Scopus, PubMed, and PsycInfo were searched using the terms [("suicide" OR "suicidal behavior" OR "suicidal attempt" OR "suicidal thought" OR "suicidal intention") AND ("prevention" OR "intervention" OR "psychosocial treatment" OR "Dialectical Behavior Therapy" OR "Cognitive Therapy" OR "psychotherap*")] AND [("Spain" OR "Spanish") OR ("Japan" OR "Japanese")]...
April 6, 2024: Healthcare (Basel, Switzerland)
#4
JOURNAL ARTICLE
Sofia Argibay, Amy H Auchincloss, M Pia Chaparro, Caroline Kravitz, Alexandra Eastus, Brent A Langellier
INTRODUCTION: Low-income immigrants who are eligible to participate in the Supplemental Nutrition Assistance Program (SNAP) participate at lower rates compared to non-immigrants. Immigrant households may be more likely to participate in SNAP if they live in areas with policies that integrate them into society and protect them from deportation. METHODS: Data on low-income immigrant households came from the 2019 American Community Survey ( N = 87,678). The outcome was whether any household member received SNAP in the previous 12 months...
2024: Journal of migration and health
#5
JOURNAL ARTICLE
Daniel Magalhães Lima, Diana Carolina Linares Chaparro, Viviana Marcela Mendez Mancera, Jenny Andrea Vela Merchán, Ana Clara Kohara Roman, Lia Puppim Buzanovsky, Ottorino Cosivi, Manuel José Sanchez-Vazquez
Amid the surge in data volume generated across various fields of knowledge, there is an increasing necessity for advanced analytical methodologies to effectively process and utilize this information. Particularly in the field of animal health, this approach is pivotal for enhancing disease understanding, surveillance, and management. The main objective of the study was to conduct a comprehensive livestock and environmental characterization of Colombian municipalities and examine their relationship with the distribution of vesicular stomatitis ( VS )...
2024: Frontiers in Veterinary Science
#6
JOURNAL ARTICLE
Hury Viridiana Hernández-Galdámez, Samia Fattel-Fazenda, Teresita N J Flores-Téllez, Mario Alejandro Aguilar-Chaparro, Jonathan Mendoza-García, Lidia C Díaz-Fernández, Eunice Romo-Medina, Yesennia Sánchez-Pérez, Jaime Arellanes-Robledo, Mireya De la Garza, Saúl Villa-Treviño, Carolina Piña-Vázquez
Hepatocellular carcinoma (HCC) is a tumor with minimal chance of cure due to underlying liver diseases, late diagnosis, and inefficient treatments. Thus, HCC treatment warrants the development of additional strategies. Lactoferrin (Lf) is a mammalian multifunctional iron-binding glycoprotein of the innate immune response and can be found as either a native low iron form (native-Lf) or a high iron form (holo-Lf). Bovine Lf (bLf), which shares many functions with human Lf (hLf), is safe for humans and has several anticancer activities, including chemotherapy boost in cancer...
April 9, 2024: Food & Function
#7
JOURNAL ARTICLE
J A Albarracin Duarte, J Chaparro Hernández, J A Rojas Aceros, J E Valoyes Gélvez, J Ascuntar, F Jaimes
OBJECTIVE: To identify the first symptoms and signs of patients with suspected infection or sepsis and their association with the composite outcome of admission to the Intensive Care Unit (ICU) or mortality. DESIGN: Prospective cohort study between June 2019 and March 2020. SETTING: Hospital Universitario San Vicente Fundación, Colombia. PATIENTS: Over 18 years of age with suspicion or confirmation of sepsis, which required hospitalization...
April 6, 2024: Revista española de anestesiología y reanimación
#8
JOURNAL ARTICLE
Soraya Colina-Matiz, Juan Hernández Leal, John Carlos Ariza-Vargas, Olga Rocio Beltrán Higuera, Cielo Ovalle-Chaparro, Natalia Lucía González Suárez, Judith Medellin-Olaya, Nadia Carolina Reina-Gamba, Catalina Correa-Mazuera, Iliana De Los Reyes Valencia, Juan Sebastián Lozano-Mosos
OBJECTIVE: To describe the experience of implementing social robotics as an adjuvant during the hospitalization process in pediatric oncology patients. METHODS: Before and after cohort study, applying an intervention with the Lego Mindstorms EV3 kit in patients between 8 and 17 years old that are hospitalized with a cancer diagnosis. We excluded patients from the intensive care unit or when their treating physician recommended so. The intervention consisted of a three-phase workshop: an open architecture story, building a car robot using the Lego Mindstorm EV3 kit, and cooperative playing activities such as races and passing obstacles...
April 2, 2024: Journal of Psychosocial Oncology
#9
JOURNAL ARTICLE
Carlos A Reyes-Ortiz, Crystall C Robinson, Donna R Williams, Brigitte A Moncayo-Hernández, Jose M Ocampo-Chaparro, Nicole Cheung, Adalberto Campo-Arias
Literature on the association between ageism and falling among older adults is limited. Using data from the nationwide cross-sectional SABE ( Salud, Bienestar y Envejecimiento ) Colombia Survey in 2015 with 18,875 participants aged ≥60 years living in the communities, the study aims to evaluate the association between perceived ageism within the family, neighborhood, health services, and public services, and recurrent falling. Participants had a mean age of 69.2 ± 7.1; 56.1% were female. Recurrent falling prevalence was 15%, and experiencing any ageism was 10%...
April 1, 2024: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
#10
JOURNAL ARTICLE
Torres-González Omar Ricardo, Flores-Soto Mario Eduardo, Tejeda-Martínez Aldo Rafael, Sánchez-Hernández Iván Moisés, Chaparro-Huerta Verónica, Soria-Fregozo Cesar, González-Garibay Angélica Sofía, Padilla-Camberos Eduardo
Leachate from municipal solid waste is a mixture of xenobiotics capable of contaminating bodies of water and causing damage to the health of living beings that inhabit or consume contaminated water. A previous study revealed the presence of heavy metals in Urban Solid Waste Transfer Station (USWTS) leachate above the permissible national and international limits. In the present study, we demonstrate that subchronic oral administration (5 and 25 % v/v) of leachate to male Wistar rats caused changes in the immunoreactivity of the glial markers: GFAP and Iba-1, accompanied by an increase in the expression of caspase-3, and a decrease in the expression of the NeuN protein...
June 2024: Toxicology Reports
#11
JOURNAL ARTICLE
Jeff R Pieper, Brendon M Anthony, Jacqueline M Chaparro, Jessica E Prenni, Ioannis S Minas
Five rootstock cultivars of differing vigor: vigorous ('Atlas™' and 'Bright's Hybrid® 5'), standard ('Krymsk® 86' and 'Lovell') and dwarfing ('Krymsk® 1') grafted with 'Redhaven' as the scion were studied for their impact on productivity, mid-canopy photosynthetic active radiation transmission (i.e., light availability) and internal fruit quality. Αverage yield (kg per tree) and fruit count increased significantly with increasing vigor (trunk cross sectional area, TCSA). Α detailed peach fruit quality analysis on fruit of equal maturity (based on the index of absorbance difference, IAD ) coming from trees with equal crop load (no...
February 22, 2024: Plant Physiology and Biochemistry: PPB
#12
JOURNAL ARTICLE
Elizabeth A Spencer, Marla C Dubinsky, Michael A Kamm, Maria Chaparro, Paolo Gionchetti, Fernando Rizzello, Javier P Gisbert, Emily K Wright, Julien D Schulberg, Amy L Hamilton, Dermot P B McGovern, Thierry Dervieux
INTRODUCTION: We evaluated baseline Clearance of anti-tumor necrosis factors and human leukocyte antigen variant (HLA DQA1*05) in combination as poor prognostic factors (PPF) of pharmacokinetic (PK) origin impacting immune response (formation of antidrug antibodies) and disease control of inflammatory bowel disease (IBD) patients treated with infliximab or adalimumab. METHODS: Baseline Clearance was estimated in IBD patients before starting treatment using weight and serum albumin concentrations...
2024: Frontiers in Immunology
#13
Elizabeth A Spencer, Marla C Dubinsky, Michael A Kamm, Maria Chaparro, Paolo Gionchetti, Fernando Rizzello, Javier P Gisbert, Emily K Wright, Julien D Schulberg, Amy L Hamilton, Dermot P B McGovern, Thierry Dervieux
[This corrects the article DOI: 10.3389/fimmu.2024.1342477.].
2024: Frontiers in Immunology
#14
JOURNAL ARTICLE
Aleix Noguera-Castells, Ignacio Campillo-Marcos, Veronica Davalos, Carlos A García-Prieto, David Valcárcel, Antonieta Molero, Laura Palomo, Norbert Gattermann, Michael Wulfert, Lorea Chaparro-González, Francesc Solé, Marta Cabezón, María J Jiménez-Lorenzo, Blanca Xicoy, Lurdes Zamora, Alessia De Stefano, Irene Casalin, Carlo Finelli, Matilde Y Follo, Manel Esteller
Real-world data have revealed that a substantial portion of patients with myelodysplastic syndromes (MDS) does not respond to epigenetic therapy with hypomethylating agents (HMAs). The cellular and molecular reasons for this resistance to the demethylating agent and biomarkers that would be able to predict the treatment refractoriness are largely unknown. In this study, we shed light on this enigma by characterizing the epigenomic profiles of patients with MDS treated with azacitidine. Our approach provides a comprehensive view of the evolving DNA methylation architecture of the disease and holds great potential for advancing our understanding of MDS treatment responses to HMAs...
March 12, 2024: British Journal of Haematology
#15
JOURNAL ARTICLE
Ivan Guerra, Francisco Barros, María Chaparro, José M Benítez, María Dolores Martín-Arranz, Ruth de Francisco, Marta Piqueras, Luisa de Castro, Ana Y Carbajo, Fernando Bermejo, Miguel Mínguez, Ana Gutiérrez, Francisco Mesonero, Fiorella Cañete, Carlos González-Muñoza, Marta Calvo, Beatriz Sicilia, Erika Alfambra, Montserrat Rivero, Alfredo J Lucendo, Carlos A Tardillo, Pedro Almela, Luis Bujanda, Manuel van Domselaar, Laura Ramos, María Fernández Sánchez, Esther Hinojosa, Cristina Verdejo, Anna Gimenez, Iago Rodríguez-Lago, Noemí Manceñido, José L Pérez Calle, Mónica Del Pilar Moreno, Pedro Genaro Delgado-Guillena, Beatriz Antolín, Patricia Ramírez de la Piscina, María José Casanova, Pilar Soto Escribano, Eduardo Martín Arranz, Isabel Pérez-Martínez, Raquel Mena, Natalia García Morales, Alicia Granja, Marta Maia Boscá Watts, Rubén Francés, Cristina Fernández, Margalida Calafat, Cristina Roig-Ramos, María Isabel Vera, Ángel Carracedo, Eugeni Domènech, Javier P Gisbert
BACKGROUND: Risk factors for developing pancreatitis due to thiopurines in patients with inflammatory bowel disease (IBD) are not clearly identified. AIM: Our aim was to evaluate the predictive pharmacogenetic risk of pancreatitis in IBD patients treated with thiopurines. METHODS: We conducted an observational pharmacogenetic study of acute pancreatitis events in a cohort study of IBD patients treated with thiopurines from the prospectively maintained ENEIDA registry biobank of GETECCU...
March 7, 2024: Digestive Diseases
#16
JOURNAL ARTICLE
María José García, Sabino Riestra, Aurelien Amiot, Mette Julsgaard, Irene García de la Filia, Margalida Calafat, Mariam Aguas, Luisa de la Peña, Cristina Roig, Berta Caballol, María José Casanova, Klaudia Farkas, Trine Boysen, Luis Bujanda, Camila Cuarán, Daniela Dobru, Fotios Fousekis, Carla Jerusalén Gargallo-Puyuelo, Edoardo Savarino, Xavier Calvet, José María Huguet, Limas Kupcinskas, Julia López-Cardona, Tim Raine, Joep van Oostrom, Javier P Gisbert, María Chaparro
BACKGROUND: The advent of new therapeutic agents and the improvement of supporting care might change the management of acute severe ulcerative colitis (ASUC) and avoid colectomy. AIMS: To evaluate the colectomy-free survival and safety of a third-line treatment in patients with ASUC refractory to intravenous steroids and who failed either infliximab or ciclosporin. METHODS: Multicentre retrospective cohort study of patients with ASUC refractory to intravenous steroids who had failed infliximab or ciclosporin and received a third-line treatment during the same hospitalisation...
March 6, 2024: Alimentary Pharmacology & Therapeutics
#17
JOURNAL ARTICLE
William Hernando Salamanca Chaparro, Constanza Navarrete, Miguel Andrés Lima-Pérez, Laura Isabel Narváez Sierra, José Dario Portillo-Miño
No abstract text is available yet for this article.
March 6, 2024: American Journal of Gastroenterology
#18
JOURNAL ARTICLE
Maria A Diaz-Mateus, Laura L Machuca, Hanan Farhat, Silvia J Salgar-Chaparro
The synergistic corrosion effect of acid-producing bacteria (APB) and magnetite on carbon steel corrosion was assessed using two different microbial consortia. A synergistic corrosion effect was observed exclusively with Consortium 2, which was composed of Enterobacter sp., Pseudomonas sp., and Tepidibacillus sp. When Consortium 2 was accompanied by magnetite, uniform corrosion and pitting rates were one-time higher (0.094 mm/year and 0.777 mm/year, respectively) than the sum of the individual corrosion rates promoted by the consortium and deposit separately (0...
March 5, 2024: Applied Microbiology and Biotechnology
#19
JOURNAL ARTICLE
Claudia Betancourtt, Alexis M Catalán, Diego F Morales-Torres, Daniela N Lopez, Valentina Escares-Aguilera, Luis P Salas-Yanquin, Joseline A Büchner-Miranda, Oscar R Chaparro, Jorge Nimptsch, Bernardo R Broitman, Nelson Valdivia
Anthropogenic biodiversity loss poses a significant threat to ecosystem functioning worldwide. Numerically dominant and locally rare (i.e., transient) species are key components of biodiversity, but their contribution to multiple ecosystem functions (i.e., multifunctionality) has been seldomly assessed in marine ecosystems. To fill this gap, here we analyze the effects of a dominant and a transient species on ecosystem multifunctionality. In an observational study conducted along ca. 200 km of the southeastern Pacific coast, the purple mussel Perumytilus purpuratus numerically dominated the mid-intertidal and the dwarf mussel Semimytilus patagonicus exhibited low abundances but higher recruitment rates...
February 27, 2024: Marine Environmental Research
#20
JOURNAL ARTICLE
Mariangela Allocca, Gaia Catalano, Edoardo V Savarino, María Chaparro, Asaf Levartovsky, George Michalopoulos, Nikos Viazis, Fotis S Fousekis, Andreas Psistakis, Daniele Noviello, Catarina Neto do Nascimento, Benedicte Caron, Vassiliki Kitsou, Giorgos Bamias, María José García, Eirini Zacharopoulou, Kalliopi Foteinogiannopoulou, Ferdinando D'Amico, Ioannis Koutroubakis, Pierre Ellul, Maria Tzouvala, Laurent Peyrin-Biroulet, Joana Torres, Flavio Caprioli, Konstantinos Karmiris, Angeliki Theodoropoulou, Konstantinos H Katsanos, Dimitrios K Christodoulou, Gerassimos J Mantzaris, Uri Kopylov, Javier P Gisbert, Silvio Danese, Fernando Magro, Fornari Carla, Gionata Fiorino
BACKGROUND: Ustekinumab and tofacitinib have recently been approved for the management of moderate to severe ulcerative colitis (UC). However, there is no evidence on how they should be positioned in the therapeutic algorithm. The aim of this study was to compare tofacitinib and ustekinumab as third-line therapies in UC patients in whom anti-TNF and vedolizumab had failed. METHODS: This was a multicenter retrospective observational study. The primary outcome was disease progression, defined as the need for steroids, therapy escalation, UC-related hospitalization and/or surgery...
February 28, 2024: United European Gastroenterology Journal
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