Himal Suthar, Tomás Manea, Dominic Pak, Megan Woodbury, Stephanie M Eick, Amber Cathey, Deborah J Watkins, Rita S Strakovsky, Brad A Ryva, Subramaniam Pennathur, Lixia Zeng, David Weller, June-Soo Park, Sabrina Smith, Erin DeMicco, Amy Padula, Rebecca C Fry, Bhramar Mukherjee, Andrea Aguiar, Sarah Dee Geiger, Shukhan Ng, Gredia Huerta-Montanez, Carmen Vélez-Vega, Zaira Rosario, Jose F Cordero, Emily Zimmerman, Tracey J Woodruff, Rachel Morello-Frosch, Susan L Schantz, John D Meeker, Akram Alshawabkeh, Max T Aung
BACKGROUND: Per- and poly-fluoroalkyl substances (PFAS) exposure can occur through ingestion of contaminated food and water, and inhalation of indoor air contaminated with these chemicals from consumer and industrial products. Prenatal PFAS exposures may confer risk for pregnancy-related outcomes such as hypertensive and metabolic disorders, preterm birth, and impaired fetal development through intermediate metabolic and inflammation pathways. OBJECTIVE: Estimate associations between maternal pregnancy PFAS exposure (individually and as a mixture) and bioactive lipids...
November 7, 2023: medRxiv