Max C Petersen, Gordon I Smith, Hector H Palacios, Sarah S Farabi, Mihoko Yoshino, Jun Yoshino, Kevin Cho, Victor G Davila-Roman, Mahalakshmi Shankaran, Ruteja A Barve, Jinsheng Yu, Jennifer H Stern, Bruce W Patterson, Marc K Hellerstein, Gerald I Shulman, Gary J Patti, Samuel Klein
There is considerable heterogeneity in the cardiometabolic abnormalities associated with obesity. We evaluated multi-organ system metabolic function in 20 adults with metabolically healthy obesity (MHO; normal fasting glucose and triglycerides, oral glucose tolerance, intrahepatic triglyceride content, and whole-body insulin sensitivity), 20 adults with metabolically unhealthy obesity (MUO; prediabetes, hepatic steatosis, and whole-body insulin resistance), and 15 adults who were metabolically healthy lean...
April 2, 2024: Cell Metabolism