Lorenz Grigull, Nicole Pulver, Lilia Goudeva, Karl-Walter Sykora, Christin Linderkamp, Andreas Beilken, Kathrin Seidemann, Hansjörg Schmid, Karl Welte, Hans-Gert Heuft
INTRODUCTION: In this retrospective, uncontrolled, observational study, the effect of granulocyte colony-stimulating factor (G-CSF)-stimulated granulocyte transfusions (GTX) in neutropenic paediatric patients with sepsis was evaluated. PATIENTS AND METHODS: Granulocytes were collected from unrelated, ABO group-matched and cytomegalic-antibody compatible donors. For neutrophil mobilization, donors received a single subcutaneous dose of glycosylated G-CSF (Lenograstim, Chugai Pharma, Japan) plus oral dexamethasone (8 mg)...
September 2006: Supportive Care in Cancer