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https://read.qxmd.com/read/30646359/prevalence-of-severe-maternal-morbidity-and-factors-associated-with-maternal-mortality-in-ontario-canada
#1
Joel G Ray, Alison L Park, Susie Dzakpasu, Natalie Dayan, Paromita Deb-Rinker, Wei Luo, K S Joseph
Importance: Severe maternal morbidity is defined by potentially life-threatening conditions. The association between the number of severe maternal morbidity (SMM) indicators and maternal death is not known. Objective: To quantify the association between the number of SMM indicators and maternal mortality. Design, Setting, and Participants: This population-based cohort study used provincial databases for data on all live birth and stillbirth hospital deliveries among women in Ontario, Canada, from April 1, 2002, to February 18, 2017...
November 2, 2018: JAMA network open
https://read.qxmd.com/read/30623864/incidence-of-pregnancy-and-disease-modifying-therapy-exposure-trends-in-women-with-multiple-sclerosis-a-contemporary-cohort-study
#2
Ai-Lan Nguyen, Eva Kubala Havrdova, Dana Horakova, Guillermo Izquierdo, Tomas Kalincik, Anneke van der Walt, Murat Terzi, Raed Alroughani, Pierre Duquette, Marc Girard, Alexandre Prat, Cavit Boz, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Jeannette Lechner-Scott, Michael Barnett, Francois Grand'Maison, Pierre Grammond, Cristina Ramo-Tello, Recai Turkoglu, Pamela McCombe, Eugenio Pucci, Maria Trojano, Franco Granella, Daniele Spitaleri, Vincent Van Pesch, Aysun Soysal, Celia Oreja-Guevara, Freek Verheul, Steve Vucic, Suzanne Hodgkinson, Mark Slee, Radek Ampapa, Julie Prevost, Jose Luis Sanchez Menoyo, Olga Skibina, Claudio Solaro, Javier Olascoaga, Cameron Shaw, Klaus Gregaard Madsen, Kerisha Naidoo, Robert Hyde, Helmut Butzkueven, Vilija Jokubaitis
BACKGROUND: Exposure to disease-modifying therapy (DMT) during early pregnancy in women with relapsing-remitting MS (RRMS) may be increasing. OBJECTIVE: To retrospectively determine incidence of pregnancy, DMT exposure and pregnancy outcomes in women with RRMS. METHODS: We identified all women with RRMS aged 15-45 years in the MSBase Registry between 2005-2016. Annualised pregnancy incidence rates were calculated using Poisson regression models...
January 3, 2019: Multiple Sclerosis and related Disorders
https://read.qxmd.com/read/30539981/late-impact-of-the-laparoscopic-treatment-of-deep-infiltrating-endometriosis-with-segmental-colorectal-resection
#3
Antonio Matos Rocha, Maurício Mendes de Albuquerque, Eduardo Miguel Schmidt, Cristiano Denoni Freitas, João Paulo Farias, Fernanda Bedin
BACKGROUND: Deep infiltrating colorectal endometriosis may severely affect the quality of life and fertility of patients. Although segmental resection is a therapeutic option that provides positive outcomes in the management of symptoms, its functional effects are still unproven. AIM: Assess the late impact of the laparoscopic approach in treating deep infiltrating endometriosis with segmental colorectal resection. METHODS: Prospective case series of 46 patients submitted to laparoscopic treatment of deep infiltrating endometriosis with segmental colorectal resection between 2013 and 2016...
December 6, 2018: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://read.qxmd.com/read/30445376/outcomes-of-singleton-versus-twin-pregnancies-in-the-fifth-and-sixth-decades
#4
Raanan Meyer, Raoul Orvieto, Ariel Israel, Aya Mohr-Sasson, Yael Timerman, Tal Gorodesky, Shlomo Toussia-Cohen, Israel Hendler, Michal J Simchen, Ronit Machtinger
BACKGROUND: Pregnancies in the fifth and sixth decades of life have been increasing, but current data are limited regarding the outcomes of twin compared with singleton pregnancies in this age group and to twin pregnancies at younger age. OBJECTIVE: To compare obstetrical and neonatal outcomes of IVF conceived pregnancies, in twin gestations of women who were ≥45 years old at delivery to singletons at similar age and twin gestations at the age of <35 years, and to assess if the complications are mainly influenced by the very advanced maternal age or by the multifetal pregnancy...
December 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/30372565/postural-orthostatic-tachycardia-syndrome-clinical-presentation-aetiology-and-management
#5
REVIEW
Artur Fedorowski
Postural Orthostatic Tachycardia Syndrome (POTS) is a variant of cardiovascular autonomic disorder characterised by an excessive heart rate increase on standing and orthostatic intolerance. POTS affects younger individuals 15-45 years old with a distinct female predominance (≈80%). The prevalence ranges between 0.2 and 1.0% in developed countries. The onset of POTS is typically precipitated by immunological stressors such as viral infection, vaccination, trauma, pregnancy, surgery or psychosocial stress. The most common complaints are dizziness, weakness, rapid heartbeat and palpitation on standing...
October 29, 2018: Journal of Internal Medicine
https://read.qxmd.com/read/30334316/the-problems-associated-with-adolescent-pregnancy-in-romania-a-cross-sectional-study
#6
Mihai Dimitriu, Cringu Antoniu Ionescu, Alexandra Matei, Roxana Viezuina, George Rosu, Corina Ilinca, Mihai Banacu, Liana Ples
RATIONALE: The extent of pregnancy in adolescents and young adults, especially in low and middle-income countries, is a source of increasing concern given its social and economic impact. AIMS AND OBJECTIVE: We hypothesized that there would be correlations between female patients becoming pregnant at a young age and practices such as harmful alcohol misuse, cigarette smoking, and drug use, the use of toxic substances, low educational attainment, and an essential absence of health care seeking about the outcome of adolescent pregnancies...
October 17, 2018: Journal of Evaluation in Clinical Practice
https://read.qxmd.com/read/30323700/associations-between-iron-deficiency-anemia-and-clinical-features-among-pregnant-women-a-prospective-cohort-study
#7
Saeed Baradwan, Abdullah Alyousef, Abdulrhman Turkistani
Background: Iron deficiency anemia (IDA) during pregnancy is a common and preventable disorder. It remains a contributing factor to maternal morbidity and mortality and is associated with high perinatal mortality rates. Objective: To determine the prevalence of IDA and its associated clinical features among pregnant women. Methods: This analytical prospective cohort study included 1,579 pregnant women who attended an antenatal clinic, Women's Specialized Hospital, King Fahad Medical City, Riyadh, Saudi Arabia, between January 2018 and April 2018...
2018: Journal of Blood Medicine
https://read.qxmd.com/read/30286056/factors-contributing-to-congenital-syphilis-cases-new-york-city-2010-2016
#8
Jennifer Sanderson Slutsker, Robin R Hennessy, Julia A Schillinger
Congenital syphilis occurs when syphilis is transmitted from a pregnant woman to her fetus; congenital syphilis can be prevented through screening and treatment during pregnancy. Transmission to the fetus can occur at any stage of maternal infection, but is more likely during primary and secondary syphilis, with rates of transmission up to 100% at these stages (1). Untreated syphilis during pregnancy can cause spontaneous abortion, stillbirth, and early infant death. During 2013-2017, national rates of congenital syphilis increased from 9...
October 5, 2018: MMWR. Morbidity and Mortality Weekly Report
https://read.qxmd.com/read/30192449/maternal-anxiety-during-pregnancy-and-the-association-with-adverse-perinatal-outcomes-systematic-review-and-meta-analysis
#9
Sophie Grigoriadis, Lisa Graves, Miki Peer, Lana Mamisashvili, George Tomlinson, Simone N Vigod, Cindy-Lee Dennis, Meir Steiner, Cara Brown, Amy Cheung, Hiltrud Dawson, Neil A Rector, Melanie Guenette, Margaret Richter
OBJECTIVE: This systematic review and meta-analysis examined the association between maternal antenatal anxiety (AA) and a range of perinatal outcomes. DATA SOURCES: Ovid MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, PsycINFO, CINAHL, Embase, and the Cochrane Library were searched to May 31, 2016, using controlled vocabulary and keywords (eg, prenatal, anxiety, preterm). STUDY SELECTION: Perinatal outcomes of women with and without AA (diagnosed or self-reported using validated scale) derived from English language, prospectively collected data were included...
September 4, 2018: Journal of Clinical Psychiatry
https://read.qxmd.com/read/30144277/early-or-late-pregnancy-loss-and-development-of-clinical-cardiovascular-disease-risk-factors-a-prospective-cohort-study
#10
J Horn, L J Tanz, J J Stuart, A R Markovitz, G Skurnik, E B Rimm, S A Missmer, J W Rich-Edwards
OBJECTIVE: To assess the association between the outcome of a woman's first pregnancy and risk of clinical cardiovascular disease risk factors. DESIGN: Prospective cohort study. SETTING AND POPULATION: Nurses' Health Study II. METHODS: Multivariable-adjusted Cox proportional hazards models were used to compute hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations between first pregnancy outcome and hypertension, type 2 diabetes, and hypercholesterolemia...
January 2019: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/30080256/effect-of-partograph-use-on-outcomes-for-women-in-spontaneous-labour-at-term-and-their-babies
#11
REVIEW
Tina Lavender, Anna Cuthbert, Rebecca Md Smyth
BACKGROUND: The partograph (sometimes known as partogram) is usually a pre-printed paper form on which labour observations are recorded. The aim of the partograph is to provide a pictorial overview of labour, and to alert midwives and obstetricians to deviations in maternal or fetal well-being and labour progress. Charts have traditionally contained pre-printed alert and action lines. An alert line, which is based on the slowest 10% of primigravid women's labours, signifies slow progress...
August 6, 2018: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/29961407/maternal-and-neonatal-outcomes-following-expectant-management-of-preterm-prelabor-rupture-of-membranes-before-viability
#12
Winnie Huiyan Sim, Hamon Ng, Penelope Sheehan
PURPOSE: To provide center-based outcome data on obstetric and neonatal complications arising from expectantly managed pregnancies affected by preterm prelabor rupture of membranes (PPROM) before viability. MATERIALS AND METHODS: We collected data on 130 consecutive pregnancies complicated by spontaneous rupture of membranes before 24 week's gestation, occurring over a 7-year period. These were women who delivered >24 h after membrane rupture, and had no signs of chorioamnionitis or advanced labor at admission...
August 13, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://read.qxmd.com/read/29945645/early-pregnancy-loss-in-belagavi-karnataka-india-2014-2017-a-prospective-population-based-observational-study-in-a-low-resource-setting
#13
Sangappa M Dhaded, Manjunath S Somannavar, Jane P Jacob, Elizabeth M McClure, Sunil S Vernekar, S Yogesh Kumar, Avinash Kavi, Umesh Y Ramadurg, Janet L Moore, Dennis P Wallace, Richard J Derman, Robert L Goldenberg, Shivaprasad S Goudar
BACKGROUND: The prevalence of early pregnancy loss through miscarriage and medically terminated pregnancy (MTP) is largely unknown due to lack of early registration of pregnancies in most regions, and especially in low- and middle-income countries. Understanding the rates of early pregnancy loss as well as the characteristics of pregnant women who experience miscarriage or MTP can assist in better planning of reproductive health needs of women. METHODS: A prospective, population-based study was conducted in Belagavi District, south India...
June 22, 2018: Reproductive Health
https://read.qxmd.com/read/29866069/assessment-of-quality-of-obstetric-care-in-zimbabwe-using-the-standard-primipara
#14
Bothwell Takaingofa Guzha, Thulani Lesley Magwali, Bismark Mateveke, Maxwell Chirehwa, George Nyandoro, Stephen Peter Munjanja
BACKGROUND: To improve maternity services in any country, there is need to monitor the quality of obstetric care. There is usually disparity of obstetric care and outcomes in most countries among women giving birth in different obstetric units. However, comparing the quality of obstetric care is difficult because of heterogeneous population characteristics and the difference in prevalence of complications. The concept of the standard primipara was introduced as a tool to control for these various confounding factors...
June 4, 2018: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/29788389/pregnancy-after-vasectomy-surgical-reversal-or-assisted-reproduction
#15
U Valerie, S De Brucker, M De Brucker, V Vloeberghs, P Drakopoulos, S Santos-Ribeiro, H Tournaye
STUDY QUESTION: Should we opt for surgical vasovasostomy or IVF/ICSI after a vasectomy? SUMMARY ANSWER: Both options reveal acceptable pregnancy rates though the time to pregnancy was significantly lower in the immediate IVF/ICSI group. WHAT IS KNOWN ALREADY: About 7.4% of men regret their vasectomy and express a renewed child wish. The choice between surgical vasectomy reversal or ICSI remains difficult for patients and their fertility specialist...
July 1, 2018: Human Reproduction
https://read.qxmd.com/read/29704487/cervical-pessary-to-reduce-preterm-birth-34-weeks-of-gestation-after-an-episode-of-preterm-labor-and-a-short-cervix-a-randomized-controlled-trial
#16
Laia Pratcorona, Maria Goya, Carme Merced, Carlota Rodó, Elisa Llurba, Teresa Higueras, Luis Cabero, Elena Carreras
BACKGROUND: To date, no intervention has proved effective in reducing the spontaneous preterm birth rate in singleton pregnancies following an episode of threatened preterm labor and short cervix remaining. OBJECTIVE: This study was designed to ascertain whether cervical pessaries could be useful in preventing spontaneous preterm birth in women with singleton pregnancies and a short cervix after a threatened preterm labor episode. STUDY DESIGN: This open randomized controlled trial was conducted in 357 pregnant women (between 240 -336 weeks) who had not delivered 48 hours after a threatened preterm labor episode and had a short cervix remaining (≤25 mm at 240 -296 weeks; ≤15 mm at 300 -336 weeks)...
July 2018: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/29649543/fate-of-recurrent-or-persistent-varicocele-in-the-era-of-assisted-reproduction-technology-microsurgical-subinguinal-redo-varicocelectomy-versus-observation
#17
Selahittin Çayan, Erdem Akbay
OBJECTIVE: To compare sperm parameters, serum hormone levels, and pregnancy and miscarriage rates between the infertile men with recurrent or persistent varicocele who underwent microsurgical subinguinal redo varicocelectomy or had observation only. MATERIALS AND METHODS: The study included 217 primary infertile men with recurrent or persistent varicocele. The patients were divided into 2 groups: 120 men underwent microsurgical subinguinal redo varicocelectomy, and 97 had observation only...
July 2018: Urology
https://read.qxmd.com/read/29625554/antiepileptic-drug-exposure-in-pregnancy-and-pregnancy-outcome-from-national-drug-usage-data
#18
Noni Richards, David Reith, Michael Stitely, Alesha Smith
BACKGROUND: Antiepileptic drugs (AEDs) are used by pregnant women to manage conditions such as epilepsy and bipolar disorder even though they pose a risk to the developing foetus. This study aimed to determine the overall use of AEDs by women during their childbearing years and women who are pregnant and the association between AED use and rates of pregnancy termination and spontaneous abortion. METHODS: Retrospective population based cohort study using administrative databases in New Zealand between 2008 and 2014...
April 6, 2018: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/29397624/-retrospective-analysis-of-diagnosis-and-treatment-of-breast-cancer-in-pregnancy
#19
F W Wang, S M Fu, Y C Jin, X H Gong, H D Cheng, K J Wu
Objective: To investigate the principles of diagnosis and treatment of breast cancer during pregnancy. Methods: Clinical data of patients with breast cancer during pregnancy admitted to Obstetrics and Gynecology Hospital of Fudan University between January 2012 to July 2017 were analyzed retrospectively. A total of 17 patients were diagnosed with breast cancer in pregnancy, the median age was 32 years (range from 25 to 45 years old), pathological staging revealed 2 patient with stage 0, 1 with stage Ⅱa, 7 with stage Ⅱb, 1 with stage Ⅲa, 2 with stage Ⅲc, 4 with stage Ⅳ...
February 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://read.qxmd.com/read/29278227/dhea-supplementation-improves-endometrial-hoxa-10-mrna-expression-in-poor-responders
#20
Önder Çelik, Mustafa Acet, Aytaç İmren, Nilüfer Çelik, Aynur Erşahin, Lebriz Hale Aktun, Barış Otlu, Sudenaz Çelik, Eray Çalışkan, Cihat Ünlü
OBJECTIVE: The study was planned to investigate whether DHEA supplementation had an impact on endometrial receptivity in women who were poor responders (POR). MATERIAL AND METHODS: Twenty-eight POR women who were undergoing hysteroscopy and five fertile control subjects were included. The POR women were equally subdivided into two separate groups as patients who were currently using DHEA and those who were not. Endometrial samples of the subjects were obtained during hysteroscopy at the late follicular phase...
December 15, 2017: Journal of the Turkish German Gynecological Association
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