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https://read.qxmd.com/read/30691017/effect-of-rosmarinic-acid-on-the-serum-parameters-of-glucose-and-lipid-metabolism-and-oxidative-stress-in-estrogen-deficient-rats
#1
Maria Zych, Ilona Kaczmarczyk-Sedlak, Weronika Wojnar, Joanna Folwarczna
Rosmarinic acid is found in medicinal and spice plants such as rosemary, lemon balm, and mint. The aim of the study was to investigate the effect of rosmarinic acid on parameters of glucose and lipid metabolism and parameters of oxidative stress in rats in the early phase of estrogen deficiency. The study was carried out on mature female Wistar rats divided into the following groups: sham-operated control rats, ovariectomized control rats, and ovariectomized rats treated orally with rosmarinic acid at a dose of 10 mg/kg or 50 mg/kg daily for 28 days...
January 25, 2019: Nutrients
https://read.qxmd.com/read/30670268/a-randomised-controlled-trial-of-lavender-lavandula-angustifolia-and-lemon-balm-melissa-officinalis-essential-oils-for-the-treatment-of-agitated-behaviour-in-older-people-with-and-without-dementia
#2
Karen Watson, Deborah Hatcher, Anthony Good
OBJECTIVE: Lavender and Lemon Balm essential oils are popular in the management of older person agitation due to their ease of application, minimal side effects and low interaction with concurrent medications. This study addressed limitations in the literature to evaluate and compare effectiveness of Lavender and Lemon Balm essential oils on the agitated behaviour of older people with and without dementia living in residential aged care facilities [RACFs]. METHODS: Forty-nine nursing home residents with dementia (n=39) and without dementia (n=10) exhibiting agitation participated in this study...
February 2019: Complementary Therapies in Medicine
https://read.qxmd.com/read/30628556/bio-herbicidal-effects-of-five-essential-oils-on-germination-and-early-seedling-growth-of-velvetleaf-abutilon-theophrasti-medik
#3
Marija Sarić-Krsmanović, Jelena Gajić Umiljendić, Ljiljana Radivojević, Ljiljana Šantrić, Ivana Potočnik, Rada Đurović-Pejčev
The evaluation of the inhibition effect exerted by the essential oils of basil (Ocimum basilicum), sage (Salvia officinalis), thyme (Thymus vulgaris), lemon balm (Melissa officinalis) and goldenrod (Solidago virgaurea) on seeds germination and early seedling growth of velvetleaf (Abutilon theophrasti Medik.) weed was examined in a laboratory bioassay. The essential oils were obtained by hydrodistillation and characterized chemically by gas chromatography coupled with both mass spectrometry and flame ionization detector...
January 10, 2019: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://read.qxmd.com/read/30583377/antioxidant-and-antimicrobial-properties-of-randomly-methylated-%C3%AE-cyclodextrin-captured-essential-oils
#4
Sourav Das, Zoltán Gazdag, Lajos Szente, Mátyás Meggyes, Györgyi Horváth, Beáta Lemli, Sándor Kunsági-Máté, Mónika Kuzma, Tamás Kőszegi
Free essential oils and their active components have a low physiochemical stability and low aqueous solubility which limit their applications as food preservatives and in packaging industry. The aim of this study was to characterize the physicochemical properties, antioxidant activities and antimicrobial activity of randomly methylated β cyclodextrin (RAMEB) encapsulated thyme oil, lemon balm oil, lavender oil, peppermint oil and their active components that include thymol, citral, linalool, menthol and borneol...
April 25, 2019: Food Chemistry
https://read.qxmd.com/read/30548118/efficacy-of-melissa-officinalis-l-lemon-balm-extract-on-glycemic-control-and-cardiovascular-risk-factors-in-individuals-with-type-2-diabetes-a-randomized-double-blind-clinical-trial
#5
Akbar Asadi, Farzad Shidfar, Mostafa Safari, Agha Fatemeh Hosseini, Hasan Fallah Huseini, Iraj Heidari, Asadollah Rajab
Melissa officinalis is a plenteous source of antioxidant flavonols and flavonoids that contain health-promoting and antidiabetic properties, so this study was undertaken to provide the first assessment of the antidiabetic properties of hydroalcoholic extract of M. officinalis in type 2 diabetic patients. We did a randomized, placebo-controlled trial which included 62 patients, receiving either M. officinalis capsules (700 mg/d; n = 31) or the placebo (n = 31) twice daily for 12 weeks. There were significant differences in serum FBS (P = 0...
December 10, 2018: Phytotherapy Research: PTR
https://read.qxmd.com/read/30253371/vasorelaxant-effect-of-the-lippia-alba-essential-oil-and-its-major-constituent-citral-on-the-contractility-of-isolated-rat-aorta
#6
R E R da Silva, L P de Morais, A A Silva, C M S Bastos, Á Pereira-Gonçalves, M R Kerntopf, I R A Menezes, J H Leal-Cardoso, R Barbosa
The Lippia alba (Mill.) N.E. Brown (Verbenaceae) species popularly known as lemon balm has sedative, analgesic and spasmolytic properties. This study aimed to evaluate the vasorelaxant effect of the L. alba essential oil (EOLa) and its major constituent, citral, rat on aorta. Isometric muscle contraction were induced by potassium (K 60 mM) or phenylephrine (PHE, 0.1 μM) in isolated aortic rings. EOLa and citral promoted a smooth muscle relaxant action, which was potentiated by the presence of the endothelium; PHE-induced contractions (0...
December 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://read.qxmd.com/read/30219475/safety-and-efficacy-of-melissa-officinalis-lemon-balm-on-apoa-i-apo-b-lipid-ratio-and-icam-1-in-type-2-diabetes-patients-a-randomized-double-blinded-clinical-trial
#7
Akbar Asadi, Farzad Shidfar, Mostafa Safari, Mojtaba Malek, Agha Fateme Hosseini, Shamsali Rezazadeh, Asadollah Rajab, Shahrzad Shidfar, Sharieh Hosseini
BACKGROUND: The purpose of this study was to investigate the safety and effects of Melissa officinalis, a good source of bioactive components, on apolipoprotein (Apo)B, Apo A-I, and their ratio, lipids ratios and intercellular adhesion molecule-1(ICAM-1) in patients with type 2 diabetes. METHODS: For the present randomized, double-blinded, placebo-controlled clinical trial, 70 type 2 diabetic patients aged 20-65 years old were randomly assigned to receive hydroalcoholic extract of M...
October 2018: Complementary Therapies in Medicine
https://read.qxmd.com/read/30087294/volatile-terpenes-and-brain-function-investigation-of-the-cognitive-and-mood-effects-of-mentha-%C3%A3-piperita-l-essential-oil-with-in-vitro-properties-relevant-to-central-nervous-system-function
#8
RANDOMIZED CONTROLLED TRIAL
David Kennedy, Edward Okello, Paul Chazot, Melanie-Jayne Howes, Samuel Ohiomokhare, Philippa Jackson, Crystal Haskell-Ramsay, Julie Khan, Joanne Forster, Emma Wightman
Extracts of several members of the monoterpene-rich Lamiaceae sub-family Nepetoideae, including those from the Salvia (sage), Melissa ( Lemon balm ) and Rosmarinus (rosemary) genera, evince cognitive and mood effects in humans that are potentially related to their effects on cholinergic and GABAergic neurotransmission. To date, despite promising in vitro properties, the cognitive and mood effects of the closely related Mentha spicata (spearmint) and Mentha piperita (peppermint) remain unexplored. This study therefore assessed the human cognitive/mood effects of the M...
August 7, 2018: Nutrients
https://read.qxmd.com/read/30045422/the-effects-of-melissa-officinalis-lemon-balm-in-chronic-stable-angina-on-serum-biomarkers-of-oxidative-stress-inflammation-and-lipid-profile
#9
Ahmad Zare Javid, Habib Haybar, Parvin Dehghan, Mohammad Hosein Haghighizadeh, Seyede Marjan Mohaghegh, Maryam Ravanbakhsh, Assieh Mohammadzadeh
BACKGROUND AND OBJECTIVES: Coronary artery disease (CAD) is a major cause of death worldwide. Chronic stable angina (CSA) is the primary sign of CAD. Oxidative stress and inflammation play a substantial role in pathogenesis and progression of CAD. The aim of this study was to investigate the effects of oral administration of powdered Melissa officinalis (MO) on biomarkers of oxidative stress, inflammation, and lipid profile in patients with CSA. METHODS AND STUDY DESIGN: A randomized, double-blind, placebo-controlled clinical trial was performed in 80 patients with CSA...
2018: Asia Pacific Journal of Clinical Nutrition
https://read.qxmd.com/read/29887909/a-comparative-study-of-melissa-officinalis-leaves-and-stems-ethanolic-extracts-in-terms-of-antioxidant-cytotoxic-and-antiproliferative-potential
#10
Elena-Alina Moacă, Claudia Farcaş, Alexandra Ghiţu, Dorina Coricovac, Ramona Popovici, Nela-Loredana Cărăba-Meiţă, Florina Ardelean, Diana Simona Antal, Cristina Dehelean, Ştefana Avram
Melissa officinalis L. has attracted an increased interest in recent years due to its multiple pharmacological effects. This study aimed to compare two M. officinalis ethanolic extracts, obtained from leaves and stems, with regard to their antioxidant activity, total phenolic content, and cytotoxic effects. M. officinalis ethanolic extracts showed a very good antioxidant activity in the DPPH test, correlated with the content in total phenols: higher in the case of M. officinalis from leaves extract (32.76 mg GAE/g) and lower for M...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://read.qxmd.com/read/29796033/effect-of-melissa-officinalis-lemon-balm-on-sexual-dysfunction-in-women-a-double-blind-randomized-placebo-controlled-study
#11
Zahra Darvish-Mofrad-Kashani, Elham Emaratkar, Fataneh Hashem-Dabaghian, Fatemeh Emadi, Firoozeh Raisi, Jale Aliasl, Mohammad Kamalinejad, Seyed Abbas Hasheminejad, Tahere Eftekhar, Nafise Zafarghandi
Hypoactive sexual desire disorder (HSDD) is the most prevalent female sexual dysfunction (FSD) and its bio-psychosocial multifactorial etiology justifies its multifaceted treatment. In Persian Medicine (PM), the weakness of the main organs (heart, brain and liver) is one of the important causes of lack of sexual desire; hence, their strengthening is a priority during treatment. Melissa officinalis is one of the medicinal plants with tonic characteristics for the main organs in PM and was used for treatment in this study...
2018: Iranian Journal of Pharmaceutical Research: IJPR
https://read.qxmd.com/read/29540983/novel-approach-to-the-development-of-functional-goat-s-milk-based-beverages-using-medicinal-plant-extracts-in-combination-with-high-intensity-ultrasound-treatment
#12
Draženka Komes, Arijana Bušić, Ana Belščak-Cvitanović, Mladen Brnčić, Tomislav Bosiljkov, Aleksandra Vojvodić, Filip Dujmić
Regardless of its highly valuable nutritive composition, goat's milk is less preferred by consumers due to its specific sensory characteristics that are very often regarded as undesirable. On the other hand, traditional medicinal plants from Lamiaceae family, due to their rich bioactive composition, especially polyphenols, and desirable aroma profile, can be used to enhance and improve bioactive and sensory properties of food. In the present study nutritively valuable beverages were produced by enrichment of goat's milk with medicinal plant extracts derived from the Lamiaceae family and stabilized by homogenization with high intensity ultrasound treatment...
December 2017: Food Technology and Biotechnology
https://read.qxmd.com/read/29433687/effects-of-a-fixed-herbal-drug-combination-ze-185-to-an-experimental-acute-stress-setting-in-healthy-men-an-explorative-randomized-placebo-controlled-double-blind-study
#13
RANDOMIZED CONTROLLED TRIAL
Sibylle Meier, Manuel Haschke, Catherine Zahner, Esther Kruttschnitt, Jürgen Drewe, Evangelia Liakoni, Felix Hammann, Jens Gaab
BACKGROUND: Considering the negative effects of stress on health, there is a growing interest in stress-reducing interventions. The present study examines the effects of a fixed combination of valerian, passion flower, lemon balm, and butterbur extracts (Ze 185) on biological and affective responses to a standardized psychosocial stress paradigm. PURPOSE: The aim of the present study was to investigate the efficacy of Ze 185 on cortisol and anxiety stress responses to acute psychosocial stress in healthy subjects...
January 15, 2018: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://read.qxmd.com/read/29412929/suitability-of-lemon-balm-melissa-officinalis-l-extract-rich-in-rosmarinic-acid-as-a-potential-enhancer-of-functional-properties-in-cupcakes
#14
Cristina Caleja, Lillian Barros, João C M Barreira, Ana Ciric, Marina Sokovic, Ricardo C Calhelha, M Beatriz, P P Oliveira, Isabel C F R Ferreira
Melissa officinalis (lemon balm) and its extracts have been frequently reported as possessing bioactive properties, offering the potential for use in development/enrichment of food products with additional functional capabilities, providing health benefits to consumers. The antioxidant, antibacterial and antifungal activity of lemon balm extract, as well as its potential hepatotoxicity were thoroughly evaluated. The extracts were then incorporated into cupcakes and their preserving effect, chemical composition, colour parameters and antioxidant activity were compared with those provided by potassium sorbate...
June 1, 2018: Food Chemistry
https://read.qxmd.com/read/29403626/a-review-of-effective-herbal-medicines-in-controlling-menopausal-symptoms
#15
REVIEW
Rahele Kargozar, Hoda Azizi, Roshanak Salari
Background: Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause. Objective: The aim of this study was to investigate the mechanisms and effects of medicinal plants employed in the treatment of menopausal symptoms...
November 2017: Electronic Physician
https://read.qxmd.com/read/29385035/biodiversity-within-melissa-officinalis-variability-of-bioactive-compounds-in-a-cultivated-collection
#16
Remigius Chizzola, Ulrike Lohwasser, Chlodwig Franz
Phytochemical characters were evaluated in a five-year-old lemon balm collection consisting of 15 and 13 subspecies officinalis and altissima accessions, respectively. Stems were lower in essential oil than leaves. First cut leaves (June) gave more oil than those of the second cut (August). Subspecies officinalis plants had leaf oils rich in geranial, neral and citronellal in various proportions in the first cut. However, in the second cut the oils from all accessions appeared very similar with 80-90% geranial plus neral...
January 31, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/29305990/effect-of-yeast-xanthophyllomyces-dendrorhous-and-plant-saint-john-s-wort-lemon-balm-and-rosemary-extract-based-functional-diets-on-antioxidant-and-immune-status-of-atlantic-salmon-salmo-salar-subjected-to-crowding-stress
#17
Sebastián Reyes-Cerpa, Eva Vallejos-Vidal, María José Gonzalez-Bown, Jonathan Morales-Reyes, Diego Pérez-Stuardo, Deborah Vargas, Mónica Imarai, Víctor Cifuentes, Eugenio Spencer, Ana María Sandino, Felipe E Reyes-López
Salmon farming may face stress due to the intensive culture conditions with negative impacts on overall performance. In this aspect, functional feed improves not only the basic nutritional requirements but also the health status and fish growth. However, to date no studies have been carried out to evaluate the effect of functional diets in salmon subjected to crowding stress. Thus, the aim of this study was to evaluate the effect of yeast extract (Xanthophyllomyces dendrorhous; diet A) and the combination of plant extracts (common Saint John's wort, lemon balm, and rosemary; diet B) on the antioxidant and immune status of Atlantic salmon grown under normal cultured conditions and then subjected to crowding stress...
March 2018: Fish & Shellfish Immunology
https://read.qxmd.com/read/29258916/potential-of-selected-lamiaceae-plants-in-anti-retro-viral-therapy
#18
REVIEW
Maja Bekut, Snežana Brkić, Nebojša Kladar, Gordana Dragović, Neda Gavarić, Biljana Božin
Constant search for new drugs with antiviral properties often extends to products of natural origin. Lamiaceae is one of the most important herbal families, well known for various biological and medicinal effects of a variety of aromatic spices, including thyme, mint, oregano, basil, sage, savory, rosemary, self-heal, hyssop, lemon balm and many others. The paper provides a review of antiviral potential of previously mentioned plants which has been demonstrated so far, with special emphasis on anti-HIV properties...
July 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://read.qxmd.com/read/29211364/insights-into-novel-anticancer-applications-for-apigenin
#19
REVIEW
Adam Kowalczyk, Agnieszka Bodalska, Marta Miranowicz, Katarzyna Karłowicz-Bodalska
Flavonoids, naturally occuring derivatives of 2-phenyl-benzo-γ-pyrone, are widespread in plants as coloring substances. Apigenin (4',5,7,-trihydroxyflavone (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), molecular formula C₁₅H₁₀O⁵, is a flavonoid present in many fruits and vegetables, primarily in citrus fruits, apples, parsley and celery leaves. It is also found in some medicinal plants, including chamomile flowers, thyme, oregano, peppermint, lemon balm and yarrow, as a 7-O-glycoside with anti-inflammatory and antioxidant activity...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://read.qxmd.com/read/29168225/gaba-modulating-phytomedicines-for-anxiety-a-systematic-review-of-preclinical-and-clinical-evidence
#20
REVIEW
Karen Savage, Joseph Firth, Con Stough, Jerome Sarris
Anxiety disorders are chronic and functionally disabling conditions with high psychological stress, characterised by cognitive symptoms of excessive worry and focus difficulties and physiological symptoms such as muscle tension and insomnia. Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter within the central nervous system and is a key target of pharmacotherapies in the treatment of anxiety. Although current pharmaceutical treatments are often efficacious, they may cause undesirable side effects including cognitive decrements and withdrawal symptoms...
January 2018: Phytotherapy Research: PTR
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