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https://read.qxmd.com/read/30786108/gastrostomy-tubes-appear-to-be-safe-following-pediatric-orthotopic-heart-transplant
#1
Rick D Vavolizza, David F Grabski, Daniel E Levin, Jeffrey W Gander
BACKGROUND: Gastrostomy tube (GT) placement is a common pediatric surgical procedure typically indicated for oral aversion. This may develop in patients with congenital heart disease (CHD) who require an orthotopic heart transplant (OHT). The safety profile of GT placement in OHT patients who are immunosuppressed is unknown. Given the potential increased risk of wound site complications on a patient receiving immunosuppression, we sought to determine the safety profile of GT placement in pediatric patients with OHT...
February 20, 2019: Pediatric Transplantation
https://read.qxmd.com/read/30784181/in-vivo-molecular-engineering-of-the-urethra-for-treatment-of-stress-incontinence-using-novel-biomimetic-proteoglycans
#2
Alicia S Kriete, Natasha Ginzburg, Nima Shah, Richard B Huneke, Emily Reimold, Katsiaryna Prudnikova, Owen Montgomery, J Steve Hou, Evan R Phillips, Michele S Marcolongo
Stress urinary incontinence (SUI), a serious condition which affects ~56% of postmenopausal women, is the involuntary leakage of urine through urethra during physical activity that causes an increase in abdominal pressure. SUI is associated with a decrease in compliance and volume of urethral tissue, likely due to a reduced proteoglycan: collagen ratio in the extracellular matrix and collagen disorganization. Here, we investigated the use of biomimetic proteoglycans (BPGs) to molecularly engineer urethral tissue of New Zealand White rabbits to examine biocompatibility in vivo...
February 19, 2019: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://read.qxmd.com/read/30782895/effectiveness-and-cost-effectiveness-of-basic-versus-biofeedback-mediated-intensive-pelvic-floor-muscle-training-for-female-stress-or-mixed-urinary-incontinence-protocol-for-the-opal-randomised-trial
#3
Suzanne Hagen, Doreen McClurg, Carol Bugge, Jean Hay-Smith, Sarah Gerard Dean, Andrew Elders, Cathryn Glazener, Mohamed Abdel-Fattah, Wael Ibrahim Agur, Jo Booth, Karen Guerrero, John Norrie, Mary Kilonzo, Gladys McPherson, Alison McDonald, Susan Stratton, Nicole Sergenson, Aileen Grant, Lyndsay Wilson
INTRODUCTION: Accidental urine leakage is a distressing problem that affects around one in three women. The main types of urinary incontinence (UI) are stress, urgency and mixed, with stress being most common. Current UK guidelines recommend that women with UI are offered at least 3 months of pelvic floor muscle training (PFMT). There is evidence that PFMT is effective in treating UI, however it is not clear how intensively women have to exercise to give the maximum sustained improvement in symptoms, and how we enable women to achieve this...
February 19, 2019: BMJ Open
https://read.qxmd.com/read/30777542/incidence-of-urinary-complications-with-double-j-stents-in-kidney-transplantation
#4
Mahir Kırnap, Fatih Boyvat, Adnan Torgay, Gökhan Moray, Sedat Yıldırım, Mehmet Haberal
OBJECTIVES: Ureteral complications remain a major source of morbidity and occasional mortality in renal transplant. Among all ureteral complications, leaks are the most frequently encountered in the early posttransplant period. The routine use of a double-J ureteric stent remains controversial, with reported increased incidence of urinary tract infection. Here, we retrospectively compared the efficacy of a double J stent in kidney transplant patients to investigate ureteral complication incidence in our center...
January 2019: Experimental and Clinical Transplantation
https://read.qxmd.com/read/30742396/-a-role-of-fesoterodine-in-treatment-of-overactive-bladder
#5
Yu A Kupriyanov, G R Kasyan, D Yu Pushkar
The muscarinic receptors have been used as target in treatment of overactive bladder (OAB) for a long time. These patients have complaints of urgency, increased urinary frequency and nocturia, sometimes with urinary incontinence (involuntary urine leakage which is associated with abrupt and strong desire to void). Fesoterodine is a prodrug that is structurally and functionally associated with tolterodine and it is the novel drug for OAB treatment. As a result of fesoterodine cleavage by non-specific esterase, the active metabolite 5-hydroxymethyl tolterodine (5-HMT) is formed...
December 2018: Urologii︠a︡
https://read.qxmd.com/read/30742372/-urodynamics-study-in-patients-with-urinary-incontinence-after-surgical-treatment-of-localized-prostate-cancer
#6
I A Aboyan, V E Aboyan, Yu N Orlov, S M Pakus, D I Pakus
AIM: Radical treatment of prostate cancer (PCa) is often associated with the development of urinary incontinence (UI). The etiology of UI after prostatectomy is multifactorial and can be caused by both urethral sphincter deficiency and bladder dysfunction. To date, there are no comparative studies of the development of UI in patients after either organ-preserving treatment or radical prostatectomy (RP). Considering this fact, our aim was to carry out the comparative assessment of urodynamic changes in these categories of patients...
December 2018: Urologii︠a︡
https://read.qxmd.com/read/30704907/pelvic-floor-muscle-training-versus-no-treatment-or-inactive-control-treatments-for-urinary-incontinence-in-women-a-cochrane-systematic-review-abridged-republication
#7
REVIEW
Licia P Cacciari, Chantale Dumoulin, E Jean Hay-Smith
BACKGROUND: Pelvic floor muscle training is the most commonly used physical therapy treatment for women with urinary incontinence. OBJECTIVES: To assess the effects of Pelvic floor muscle training for women with urinary incontinence in comparison to a control treatment and to summarize relevant economic findings. METHODS: Cochrane Incontinence Group Specialized Register (February 12, 2018). SELECTION CRITERIA: Randomized or quasi-randomized trials in women with stress, urgency or mixed urinary incontinence (symptoms, signs, or urodynamic)...
January 22, 2019: Brazilian Journal of Physical Therapy
https://read.qxmd.com/read/30702552/preservation-versus-non-preservation-of-left-colic-artery-in-colorectal-cancer-surgery-an-updated-systematic-review-and-meta-analysis
#8
Xuyang Yang, Pingfan Ma, Xubing Zhang, Mingtian Wei, Yazhou He, Chaoyang Gu, Xiangbing Deng, Ziqiang Wang
BACKGROUND: It remains unclear whether or not preservation of the left colic artery (LCA) for colorectal cancer surgery. The objective of this updated systematic review and meta-analysis is to evaluate the current scientific evidence of LCA non-preservation versus LCA preservation in colorectal cancer surgery. METHODS: A systematic search was conducted in the Medline, Embase, PubMed, Cochrane Library, ClinicalTrials, Web of Science, China National Knowledge Infrastructure and Chinese BioMedical Literature Database, and reference without limits...
February 2019: Medicine (Baltimore)
https://read.qxmd.com/read/30699433/mini-sling-ophira-at-8-years-follow-up-does-it-sustain-results
#9
Lucas Mira Gon, Cassio Luis Zanettini Riccetto, Caio Cesar Citatini de Campos, Brunno Raphael Iamashita Voris, Leonardo O Reis, Paulo Cesar Rodrigues Palma
PURPOSE: To evaluate mini-sling long-term results and correlate them to failure predictors. Many studies show comparable results among different single-incision slings developed as an attempt to reduce complications while keeping good results, but there is a lack of evidence about mini-slings outcomes in the long term. METHODS: This prospective, single-center study evaluated 40 patients for long-term outcomes after mini-sling placement. Objective cure was defined as leakage of less than 1 g in 1-hour pad-test and no leakage at Valsalva maneuver...
January 30, 2019: Urologia Internationalis
https://read.qxmd.com/read/30692479/-a-case-of-laparoscopic-low-anterior-resection-and-adrenalectomy-for-rectal-cancer-and-adrenal-tumor
#10
Masashi Kato, Akihiko Murata, Shinsuke Nishikawa, Shinji Tsutsumi, Kensuke Okano, Yoichi Yamauchi, Motonari Ohashi, Akitoshi Kimura, Minoru Umehara, Naoki Hashimoto, Yutaka Umehara, Kenichi Takahashi
A 70-year-old woman had consulted a doctor at a former clinic because of bloody stool and colonoscopy revealed a type 2 tumor of the rectum. She was referred to our hospital for further examinations and treatment. Preoperative blood examination showed an elevated HbA1c level of 10.2%. Abdominal CT showed a 25mm tumor in the left adrenal gland. The patient was diagnosed with adrenal Cushing's syndrome based on low ACTH levels, disappearance of circadian variation in blood cortisol levels, lack of inhibition by dexamethasone loading, and high urinary cortisol levels...
December 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://read.qxmd.com/read/30686479/biofeedback-for-pelvic-floor-muscle-training-in-women-with-stress-urinary-incontinence-a-systematic-review-with-meta-analysis
#11
REVIEW
Erica Feio Carneiro Nunes, Luciana Maria Malosá Sampaio, Daniela Aparecida Biasotto-Gonzalez, Reny Costa Dos Reis Nagano, Paulo Roberto Garcia Lucareli, Fabiano Politti
BACKGROUND: Several clinical effects have been attributed to the use of biofeedback (BF) as an adjuvant in the treatment of women with stress urinary incontinence (SUI). OBJECTIVES: To determine whether BF is more effective than other interventions for women with SUI in terms of quantification of urine leakage, episodes of urinary loss, quality of life and muscle strength. DATA SOURCES: Science Direct, Embase, MEDLINE, Pedro, SciELO, CINAHL and LILACS from January 2000 to February 2017...
March 2019: Physiotherapy
https://read.qxmd.com/read/30685371/intravenous-and-intraventricular-daptomycin-plus-intravenous-linezolid-treatment-of-an-infant-with-vancomycin-resistant-enterococci-induced-ventriculoperitoneal-shunt-infection
#12
Ayse Şahin, Nazan Dalgic
The rate of ventriculoperitoneal (VP) shunt infection is reported between 3% and 20%. Vancomycin-Resistant Enterococci (VRE) are increasingly prevalent nasocomial pathogens worldwide and they rarely cause infections to the central nervous system. Daptomycin is a cyclic lipopeptide effective antibiotic due to its rapid bactericidal effect. It is a life-saving treatment option for meningitis, bacteriemia, sepsis, endocarditis and urinary system infections caused by VRE. Here, we presented a 2.5-month-old male patient diagnosed with ventriculoperitoneal shunt infection caused by VRE faecium...
January 24, 2019: World Neurosurgery
https://read.qxmd.com/read/30672208/-comment-on-the-two-randomized-clinical-trials-on-acupuncture-from-journal-of-the-american-medical-association
#13
(no author information available yet)
In June 27, 2017, there were two acupuncture clinical trials published in Journal of the American Medical Association ( JAMA ). The conclusions were that electroacupuncture could relieve the leakage of urine of female stress urinary incontinence and that acupuncture with clomiphene or not could not improve the live birth rate of female with polycystic ovarian syndrome, compared with shallow insertion at non-acupoint combined with clomiphene placebo. The Youth Committee of the China Association of Acupuncture-Moxibustion held an academic salon about the above two trials on September 7, 2017...
November 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://read.qxmd.com/read/30651036/effect-of-udenafil-administration-on-postmicturition-dribbling-in-men-a-prospective-multicenter-double-blind-placebo-controlled-randomized-clinical-study
#14
Kyungtae Ko, Won Ki Lee, Sung Tae Cho, Young Gu Lee, Tae Young Shin, Min Soo Choo, Jun Hyun Han, Seong Ho Lee, Cheol Young Oh, Jin Seon Cho, Hyun Cheol Jeong, Dae Yul Yang
PURPOSE: Postmicturition dribbling (PMD) is a stressful symptom in middle-aged men characterized by urinary leakage after the completion of normal voiding. Appropriate treatments have not yet been introduced. This study assessed the efficacy of treatment of PMD with 75 mg udenafil daily. MATERIALS AND METHODS: The study included 138 men with regular sexual lifestyles. The Hallym PMD questionnaire (HPMDQ) was used to assess PMD symptoms. After all basic examinations, patients were randomly assigned to either udenafil or placebo...
January 16, 2019: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://read.qxmd.com/read/30635932/comparison-of-initial-leak-pressures-after-single-and-double-layer-cystotomy-closure-with-barbed-and-nonbarbed-monofilament-suture-material-in-an-ex-vivo-ovine-model
#15
Daniel J Duffy, Cameron G Kindra, George E Moore
OBJECTIVE: To compare initial leakage pressure after double-layer inverting and single-layer appositional closures with unidirectional barbed suture or an analogous monofilament absorbable suture in an ex vivo ovine model. STUDY DESIGN: Experimental study. SAMPLE POPULATION: Ovine cadaveric bladders (n = 48). METHODS: A 4-cm ventral cystotomy was performed in each bladder. Bladders were randomly divided into 4 groups (n = 12 each group) and sutured in an open setting with a single-layer appositional or a double-layer inverting pattern of unidirectional 2-0 barbed or an analogous monofilament suture...
January 12, 2019: Veterinary Surgery: VS
https://read.qxmd.com/read/30620148/the-effect-of-high-impact-crossfit-exercises-on-stress-urinary-incontinence-in-physically-active-women
#16
Jean Yang, Julie W Cheng, Hillary Wagner, Everett Lohman, Sang H Yang, Gene Austin Krishingner, Alexandra Trofimova, Muhannad Alsyouf, Andrea Staack
AIMS: The impact of CrossFit (high energy and intensity exercise) on SUI has not been well described. This study evaluates the incidence of SUI in physically active women, and examines specific exercises that can increase SUI. METHODS: A cross-sectional study was conducted in women from four CrossFit centers and one aerobic center for comparison. Participants were surveyed regarding baseline demographics, activity levels, severity, and frequency of leakage during CrossFit exercises as well as preventative strategies against SUI...
January 8, 2019: Neurourology and Urodynamics
https://read.qxmd.com/read/30611650/neomycin-polymyxin-or-gentamicin-bladder-instillations-decrease-symptomatic-urinary-tract-infections-in-neurogenic-bladder-patients-on-clean-intermittent-catheterization
#17
K H Huen, F Nik-Ahd, L Chen, S Lerman, J Singer
INTRODUCTION: Recurrent urinary tract infections (UTIs) are common in patients with neurogenic bladder (NGB) performing clean intermittent catheterization (CIC) treated with or without oral antibiotic prophylaxis. OBJECTIVE: The authors aim to determine if daily neomycin-polymyxin or gentamicin bladder instillations reduce the rate of symptomatic UTIs, the need for oral antibiotic prophylaxis, emergency department (ED) visits for UTI, and inpatient hospitalizations for UTI in patients with NGB on CIC...
December 12, 2018: Journal of Pediatric Urology
https://read.qxmd.com/read/30606645/-robotic-assisted-laparoscopic-implantation-of-artificial-urinary-sphincter-ams-800-%C3%A2-in-woman-single-center-experience
#18
P Callerot, M-A Perrouin-Verbe, M Thoulouzan, A Valeri, G Fournier
INTRODUCTION: Artificial urinary sphincter (AUS) is the treatment of last resort of stress urinary incontinence (UI) due to intrinsic sphincter deficiency (IS). The implantation procedure has been described by open surgery and laparoscopy with a significative rate of complication by Lucas et al. (2012) and Costa et al. (2001). We report our experience of implantation of SUA by robotic-assisted laparoscopy (R-SUA) in 17 patients among 3 revisions. MATERIAL AND METHODS: Between 2012 and 2017, 17 patients have been consecutively included...
December 31, 2018: Progrès en Urologie
https://read.qxmd.com/read/30599852/ct-guided-nephrostomy-an-expedient-tool-for-complex-clinical-scenarios
#19
Maximilian Peter Brandt, Thomas Lehnert, Theresa Czilwik, Hendrik Borgmann, Tatjana Gruber-Rouh, Axel Thalhammer, Elisabeth Hannah Adam, Christian Thomas, Georg Bartsch, Axel Haferkamp, Thomas Joseph Vogl, Igor Tsaur
INTRODUCTION & OBJECTIVES: Percutaneous nephrostomy [1] has emerged as a pivotal approach in the therapeutic management of the obstructed urinary tract. A consecutive incorporation of ultrasonic and radiographic guidance, the approach experienced an almost ubiquitious distribution while most centers currently applying either one or both of these tools jointly. However, success of ultrasound-guidance is limited in obese patients and non-dilated uropathy. In turn, fluoroscopy usually requires an opacification of the urinary collecting system by intravenous or antegrade contrast media injection, which might be harmful for already impaired renal function, raise intrapelvic pressure and augment the risk of sepsis and hemorrhage...
January 2019: European Journal of Radiology
https://read.qxmd.com/read/30597036/a-novel-splicing-variant-of-small-nucleolar-rna-host-gene-4-is-a-podocyte-selective-non-coding-rna-upregulated-in-response-to-puromycin-aminonucleoside-induced-podocyte-injury
#20
Aya Horikawa, Tomomi Yoneda, Eishin Yaoita, Katsushi Yamaguchi, Shuji Shigenobu, Mizuki Kuramochi, Jyoji Yamate, Takashi Inui, Osamu Ishibashi
Podocytes are terminally differentiated cells that function as the glomerular filtration barrier in the kidney, and podocyte injury leads to serious proteinuria and podocyte leakage into urine. Recent studies have demonstrated that the number of urinary podocytes is correlated with the progression of glomerular diseases. Therefore, urinary podocytes may serve as an indicator of podocyte injury. In this study, to explore podocyte injury-related genes, we performed comprehensive transcriptome analysis of primary rat podocytes cultured in the presence or absence of puromycin aminonucleoside (PAN), an agent commonly used to induce podocyte injury...
December 31, 2018: Journal of Biochemistry
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