Read by QxMD icon Read

MCA İnfarction

Yao Meng, Mingli Li, Yannan Yu, Yuyuan Xu, Shan Gao, Feng Feng, Wei-Hai Xu
BACKGROUND: We aimed to quantitatively assess the vessel morphology of middle cerebral artery (MCA) atherosclerosis and explore its value in discriminating plaque types. METHODS: Patients were selected from a high-resolution magnetic resonance imaging (HRMRI) study from January 2007 to December 2015. One hundred and three patients with acute cerebral infarcts due to MCA stenosis (>50%) and eighty-nine patients with asymptomatic MCA stenosis (>50%) were included...
February 15, 2019: Journal of the Neurological Sciences
Munehiro Otsuka, Yuichiro Kikkawa, Tomoya Kamide, Kaima Suzuki, Aoto Shibata, Toshiki Ikeda, Hiroki Kurita
BACKGROUND: This study aimed to investigate factors related to improvement of hemodynamics and evaluated the usefulness of intraoperative Doppler for predicting postoperative hemodynamics in patients with cerebrovascular atherosclerotic steno-occlusive disease (CASD) of the internal carotid artery (ICA) or middle cerebral artery (MCA) who were treated with extracranial-intracranial (EC-IC) bypass surgery. METHOD: Forty-eight patients with CASD of the ICA or MCA who were treated by superficial temporal artery to middle cerebral artery bypass with a follow-up longer than 12 months were enrolled...
February 18, 2019: Acta Neurochirurgica
Changwei Yuan, Hongzhou Duan, Zhiqiang Yi, Yang Zhang, Jiayong Zhang
BACKGROUND: A non-bifurcating cervical carotid artery (NBCCA) is a rare anatomical variation of the carotid artery which directly arises from the common carotid artery (CCA) without forming a bifurcation. A rare case of an NBCCA associated with middle cerebral artery (MCA) stenosis is reported herein. CASE DESCRIPTION: A 70-year-old man was admitted to the hospital for fresh infarctions in the left frontoparietal lobe. The angiography imaging showed severe atherosclerotic stenosis in the left MCA associated with an ipsilateral NBCCA...
February 11, 2019: World Neurosurgery
Slaven Pikija, Jozef Magdic, Laszlo K Sztriha, Monika Killer-Oberpfalzer, Nele Bubel, Anita Lukic, Johann Sellner
Ischemic stroke related to tandem internal carotid and middle cerebral artery (TIM) occlusion is a challenging condition where endovascular treatment (EVT) is an emerging revascularization option. The identification of factors influencing clinical outcomes can assist in creating appropriate therapeutic algorithms for such patients. This study aimed to evaluate prognostic factors in the context of EVT for TIM occlusion. We performed a retrospective study of consecutive patients with TIM occlusion admitted within 6 h from symptom onset to two tertiary stroke centers...
February 10, 2019: Journal of Clinical Medicine
Niyaz Ahmad, Abeer M Al-Subaiec, Rizwan Ahmad, Sonali Sharma, Md Aftab Alam, Mohammad Ashafaq, Rehan Abdur Rub, Farhan Jalees Ahmad
OBJECTIVE: Enhancement of CS-GA-PCL-NPs (Glycyrrhizic Acid-encapsulated-chitosan-coated-PCL-Nanoparticles) bioavailability in brain. METHODS: Double emulsification solvent evaporation method in order to develop CS-PCL-NPs (Chitosan-coated-PCL-Nanoparticles) followed by characterization of particle size and distribution, zeta potential, encapsulation efficiency and drug release (in vitro). To determine drug-uptake and its pharmacokinetic profile in brain as well as plasma, UHPLC (triple quadrupole Q-trap) MS/MS method was developed and optimized for CS-GA-PCL-NPs as well as to follow-up examined effective role of optimized NPs in reduction of all brain injury parameters after MCAO through the grip strength, locomotor activity, inflammatory cytokines levels, measurement of infarction volume and histopathological changes in neurons with safety/toxicity after i...
December 2019: Artificial Cells, Nanomedicine, and Biotechnology
Hui Wang, Xin-Jie Ning, Chuan Chen, Cong Lin, Jia-Ji Liang, Yu-Zhang Li
BACKGROUND: We report a case of a foreign body embolus to the middle cerebral artery and reviewed similar cases previously reported. METHODS: A 30-year-old man was seen 72 days after a penetrating neck injury with a 1-month history of numbness in the left limb and impairment of the fine movement in the left hand. Radiological examination revealed a foreign body in the M2 portion of the right middle cerebral artery (MCA). The patient received arteriotomy and in situ suturing...
January 29, 2019: British Journal of Neurosurgery
Hayato Suzuki, Suguru Yamaguchi, Katsuhiro Nishino, Taizen Nakase, Hiroaki Shimizu
The pathogenesis of anterior choroidal artery (AChA) territory infarction includes various mechanisms, but hemodynamic causes are rare and difficult to diagnose. 77- year-old man, who had moderate left ICA stenosis and he had treated with STA-MCA bypass surgery for severe symptomatic left MCA stenosis 10 years earlier, was admitted with right hemiparesis and confused state. On admission, magnetic resonance imaging and angiography demonstrated patent bypass, but severe stenosis of left ICA with no opacification of the left AChA and A1 portion of the left ACA...
December 5, 2018: Neurology International
David W Baker, Nicholas J Whitehead, Malcolm Barlow
BACKGROUND: Mycotic coronary aneurysms (MCA) are rare but often lead to significant morbidity and mortality. Evidence on the topic is limited to case reports and small case series. A systematic review was performed to improve understanding of this challenging diagnosis. A case report prompting this review is also included. METHODS: Relevant articles were identified by searching databases Medline and Google Scholar for terms 'mycotic coronary aneurysm'. Manual searching from article references identified further case reports...
December 19, 2018: Heart, Lung & Circulation
Nan N Jiang, Crystal Fong, Demetrios J Sahlas, Sandra Monteiro, Ramiro Larrazabal
PURPOSE: Recent trials have demonstrated superior outcomes with combination IV-tPA and endovascular therapy (EVT) within 6 hours of symptom onset in patients with proximal vessel occlusion (ICA, M1, or proximal M1/M2) compared to IV-tPA alone. The current standard of diagnosis for consideration of EVT is CT angiogram (CTA). Unfortunately, not all hospitals are equipped with CTA, and the decision to transfer to tertiary centers is often based on nonenhanced CT. Ipsilateral conjugate gaze deviation (CGD) is associated with worse outcomes and larger infarcts in acute ischemic stroke...
January 14, 2019: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Kathryn M Wagner, Visish M Srinivasan, Aditya Srivatsan, Michael G Z Ghali, Ajith J Thomas, Alejandro Enriquez-Marulanda, Abdulrahman Y Alturki, Christopher S Ogilvy, Maxim Mokin, Anna L Kuhn, Ajit Puri, Ramesh Grandhi, Stephen Chen, Jeremiah Johnson, Peter Kan
OBJECTIVEWith the increasing use of flow diversion as treatment for intracranial aneurysms, there is a concomitant increased vigilance in monitoring complications. The low porosity of flow diverters is concerning when the origins of vessels are covered, whether large circle of Willis branches or critical perforators. In this study, the authors report their experience with flow diverter coverage of the lenticulostriate vessels and evaluate their safety and outcomes.METHODSThe authors retrospectively reviewed 5 institutional databases of all flow diversion cases from August 2012 to June 2018...
January 11, 2019: Journal of Neurosurgery
You Gyoung Yi, Dae Yul Kim, Woo Hyun Shim, Joo Young Oh, Ho Sung Kim, Minji Jung
INTRODUCTION: The mechanism of functional recovery in right hemisphere (RH) stroke patients when attempting to comprehend a proverb has not been identified. We previously reported that there is bilateral hemisphere involvement during proverb comprehension in the normal population. However, the underlying mechanisms of proverb comprehension following a right middle cerebral artery (MCA) infarction have not yet been fully elucidated. METHODS: We here compared the brain regions activated by literal sentences and by opaque or transparent proverbs in right MCA infarction patients using functional magnetic resonance imaging (fMRI)...
December 26, 2018: Brain and Behavior
Jan Rahmig, Sigrid Wöpking, Eric Jüttler, Lorenz Uhlmann, Ronald Limprecht, Jessica Barlinn, Gabriele Schackert, Heinz Reichmann, Hauke Schneider
BACKGROUND: Decompressive hemicraniectomy improves survival rates and functional outcome in patients with space-occupying middle cerebral artery (MCA) infarction. We sought to determine clinical outcomes in elderly patients with MCA infarction treated with hemicraniectomy and to identify factors associated with functional outcome. METHODS: We performed a prospective, single-center observational study aiming to include patients aged ≥ 61 years with large MCA infarction treated with hemicraniectomy...
December 19, 2018: Neurocritical Care
(no author information available yet)
OBJECTIVERevascularization surgery is a safe and effective surgical treatment for symptomatic moyamoya disease (MMD) and has been shown to reduce the frequency of future ischemic events and improve quality of life in affected patients. The authors sought to investigate the occurrence of acute perioperative occlusion of the contralateral internal carotid artery (ICA) with contralateral stroke following revascularization surgery, a rare complication that has not been previously reported.METHODSThis study is a retrospective review of a prospective database of a single surgeon's series of revascularization operations in patients with MMD...
December 14, 2018: Journal of Neurosurgery
Jun Zhang, Xiao Zhang, Jinping Zhang, Yun Song, Ju Han
BACKGROUND: Endovascular therapy has been increasingly recommended for the treatment of acute ischemic stroke with large vessel occlusion of the anterior circulation. However, occlusions of the distal cerebral artery are not uncommon and may cause clinical deficits, especially when combined with ipsilateral chronic large vessel occlusion. Therefore, in this patient population, the recognition of chronic occlusion and recanalization of the distal occlusive artery might be of great value for flow compensation...
December 8, 2018: World Neurosurgery
Luis Cartier R, Jorge Parra, Juan P Contreras S
BACKGROUND: Cerebral ptosis is understood as the bilateral paralysis of eyelid elevation linked to a stroke or hemorrhage of the middle cerebral artery (MCA). It is a transient condition, independent of the evolution of the lesion. AIM: To analyze six patients with the condition. PATIENTS AND METHODS: Report of five women and one male aged 42 to 72 years. RESULTS: All suffered an infarction or hemorrhage in the territory of the middle cerebral artery of the non-dominant hemisphere and developed a bilateral palpebral ptosis...
August 2018: Revista Médica de Chile
Junpei Koge, Seiya Kato, Tetsuya Hashimoto, Yukihiko Nakamura, Masakazu Kawajiri, Takeshi Yamada
BACKGROUND: There is increasing experimental evidence that stent retriever thrombectomy (SRT) may cause arterial wall damage, although histopathological findings focused on vessel wall injury after SRT have not fully been reported in humans. CASE DESCRIPTION: We describe an autopsy case of an 82-year-old woman who presented with acute left intracranial internal carotid artery (ICA) occlusion and received SRT. When we attempted to catheterize the M1 segment of the normal middle cerebral artery (MCA), we were not aware of a duplicated MCA, and the microcatheter was advanced into the main MCA trunk with a smaller caliber than that of the normal M1 segment...
December 6, 2018: World Neurosurgery
Reza Jahan, J Pablo Villablanca, Robert J Harris, Sandra Duarte-Vogel, Christopher K Williams, Harry V Vinters, Neal Rao, Dieter R Enzmann, Benjamin M Ellingson
BACKGROUND: A reliable animal model of ischemic stroke is vital for pre-clinical evaluation of stroke therapies. We describe a reproducible middle cerebral artery (MCA) embolic occlusion in the French Lop rabbit characterized with multimodal MRI and histopathologic tissue analysis. NEW METHOD: Fluoroscopic-guided microcatheter placement was performed in five consecutive subjects with angiographic confirmation of MCA occlusion with autologous clot. Multimodal MRI was obtained prior to occlusion and up to six hours post after which repeat angiography confirmed sustained occlusion...
December 7, 2018: Journal of Neuroscience Methods
Taichi Ishiguro, Yoshikazu Okada, Tatsuya Ishikawa, Koji Yamaguchi, Akitsugu Kawashima, Takakazu Kawamata
The effects of superficial temporal artery to middle cerebral artery (STA-MCA) double bypass on recurrent hemorrhage in the operated hemisphere in hemorrhagic moyamoya disease (HMD) have not been clearly demonstrated. This study evaluated the effectiveness of STA-MCA double bypass in the prevention of further hemorrhagic or ischemic events in the operated hemispheric sides in comparison to the conservatively treated non-operated sides. We retrospectively analyzed 52 hemispheres of 36 patients with adult-onset HMD treated with STA-MCA double bypass...
December 3, 2018: Neurosurgical Review
Christian F Freyschlag, Christian Boehme, Marlies Bauer, Johannes Kerschbaumer, Daniel Pinggera, Marina Riedmann, Claudia Unterhofer, Astrid E Grams, Michael Knoflach, Claudius Thomé
BACKGROUND: Malignant middle cerebral artery stroke is a life-threatening condition. The outcomes of surgical treatments have presented strong evidence in favor of decompressive hemicraniectomy (DHC). A significant subpopulation of patients still experience very poor outcomes. In particular, indication for DHC is based on few objective parameters to facilitate decision making. We hypothesized that larger ischemic brain volume would have a large impact on the outcome. METHODS: A cohort study of 34 patients undergoing DHC was performed using a volumetric analysis of infarction volume (measured preoperatively and again on postoperative day [POD] 1 and POD 3)...
November 29, 2018: World Neurosurgery
Suparna Das, Patrick Mitchell, Nicholas Ross, Peter Whitfield
BACKGROUND: Malignant middle cerebral artery infarctions are large space-occupying infarctions involving massive oedema, herniation, and, frequently death. Survivors are disabled. Management involves medical treatment, with or without decompressive hemicraniectomy and later duraplasty. OBJECTIVES: This meta-analysis aims to determine whether surgery is worthwhile with particular regard to views on quality of life of professionals and patients. METHODS: Study eligibility criteria A Medline search was performed with the search terms "decompressive surgery", "craniectomy", "hemicraniectomy", "decompressive hemicraniectomy", and "middle cerebral artery", "MCA" "infarct*", "stroke*", "embolus", "emboli", "thrombosis", "occlusion", "infarction", and "middle cerebral artery stroke"...
November 27, 2018: World Neurosurgery
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"