Damien Bouvier, Aymeric Cantais, Alban Laspougeas, Fleur Lorton, Yannick Plenier, Maria Cottier, Philippe Fournier, Antoine Tran, Emilie Moreau, Julie Durif, Catherine Sarret, Charline Mourgues, Franck Sturtz, Jean-Baptiste Oudart, Juliette Raffort, Philippe Gonzalo, Jean-Paul Cristol, Damien Masson, Bruno Pereira, Vincent Sapin
IMPORTANCE: Minor head trauma (HT) is one of the most common causes of hospitalization in children. A diagnostic test could prevent unnecessary hospitalizations and cranial computed tomographic (CCT) scans. OBJECTIVE: To evaluate the effectiveness of serum S100B values in reducing exposure to CCT scans and in-hospital observation in children with minor HT. DESIGN, SETTING, AND PARTICIPANTS: This multicenter, unblinded, prospective, interventional randomized clinical trial used a stepped-wedge cluster design to compare S100B biomonitoring and control groups at 11 centers in France...
March 4, 2024: JAMA Network Open