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outpatient chemotherapy

Cécile Barbaret, Marvin O Delgado-Guay, Stéphane Sanchez, Christelle Brosse, Murielle Ruer, Léa Monsarrat, Patrick Michaud, Anne Marie Schott, Eduardo Bruera, Marilène Filbet
BACKGROUND: Financial distress (FD) is common among patients with advanced cancer. Our purpose was to compare the frequency and intensity of FD and its associations with symptom distress and quality of life (QOL) in these patients in France and the U.S. MATERIALS AND METHODS: In this secondary analysis of two cross-sectional studies, we assessed data on 292 patients who received cancer care at a public hospital or a comprehensive cancer center in France (143 patients) or the U...
March 15, 2019: Oncologist
Jonathan Geograpo Navarro, Chang Moo Kang
The oncologic safety and feasibility of laparoscopic radical cholecystectomy for a preoperatively suspected gallbladder cancer is continually being challenged even in an era of minimally invasive surgery. A seventy-four-year-old woman was presented in the outpatient department with a history of fever, abdominal pain, and vomiting. CT scan showed an irregular wall thickening of the body to the cystic duct of the gallbladder and portocaval lymph node. In addition, EUS revealed no subserosal invasion of the tumor...
February 2019: Annals of Hepato-Biliary-Pancreatic Surgery
Larissa Nascimento Dos Santos, Luciana Castaneda, Suzana Sales de Aguiar, Luiz Claudio Santos Thuler, Rosalina Jorge Koifman, Anke Bergmann
OBJECTIVE:  To analyze the factors associated with health-related quality of life (HRQoL) in women with cervical cancer (CC) in a single center in Rio de Janeiro, state of Rio de Janeiro, Brazil. METHODS:  A cross-sectional study in women with a diagnosis of CC followed-up in the gynecology outpatient clinic of the Hospital do Câncer II (HCII, in the Portuguese acronym) of the Instituto Nacional de Câncer (INCA, in the Portuguese acronym). The data were collected from March to August 2015...
March 7, 2019: Revista Brasileira de Ginecologia e Obstetrícia
Bamidele Johnson Alegbeleye
BACKGROUND: A case is reported of innocuous intestinal obstruction requiring surgical intervention that was confirmed to be Crohn's disease histopathologically in a resource-constrained rural mission hospital in Cameroon. CASE PRESENTATION: A 70-year man of Kumbo origin from Northwest region of Cameroon with a history of crampy right lower-quadrant abdominal pain, non-bloody, non-mucoid diarrhea alternating with constipation presented to my institution. Abdominal examination of the patient revealed an ill-defined mass in the right iliac fossa and visible peristalsis...
March 7, 2019: Journal of Medical Case Reports
Mansooreh Rooeintan, Mojgan Khademi, Tahereh Toulabi, Fatemeh Heshmati Nabavi, Mojtaba Gorji
Aim: This study aimed to explain the postdischarge care needs of cancer patients. Materials and Methods: In this qualitative content analysis, nine cancer patients presenting to the department of chemotherapy or an oncologist's office, four of patients' accompaniments, four nurses, and two oncologists were selected purposefully until data saturation. They underwent deep individual interviews. Data were collected from October 2016 to June 2017. Data were analyzed using Zhang's method with an inductive approach to extract the themes...
January 2019: Indian Journal of Palliative Care
Maria Lavdaniti, Dimitra Anna Owens, Polixeni Liamopoulou, Kalliopi Marmara, Efrosini Zioga, Michael S Mantzanas, Eftychia Evangelidou, Eugenia Vlachou
PURPOSE: To assess breast cancer patients' quality of life six months after the completion of adjuvant chemotherapy, and to investigate factors affecting this. METHODS: The study was conducted in one large hospital located in a major Greek city. A convenience sample of 61 breast cancer outpatients was recruited. A questionnaire, including the SF-36 scale and questions regarding demographic and clinical information, was used to collect data. RESULTS: The mean age of the patients was 51...
February 24, 2019: Diseases (Basel)
Diana Comerford, Raakhee Shah
Ambulatory care (AC) involves providing inpatient chemotherapy and supportive care as an outpatient service. Nurses and the multidisciplinary team (MDT) have a major role in this. AC at a major London teaching hospital trust is a nurse-led service, headed by specialist cancer nurses with excellent knowledge of the needs and priorities of patients undergoing intensive treatment. An experienced MDT, including administrative support, maintains safety and continuity of care. The nurses, MDT and patient work closely to promote the patient's wellbeing, self-management and trust...
February 28, 2019: British Journal of Nursing: BJN
James Turro, Pratiksha Singh, Manbeer Singh Sarao, Satish Tadepalli, Pramil Cheriyath
Background : Burkitt lymphoma is a rare, aggressive and rapidly fatal, B-cell non-Hodgkin's lymphoma. It has an incidence of 0.4/100,000 age-adjusted to the USA standard population. Here we describe the case of a 77-year-old patient who presented with Burkitt lymphoma. Case : A 77-year-old male presented to his primary care physician with fatigue and listlessness and was referred to the hospital with a white blood cell count (WBC)-23.7 K/uL (neutrophils 37%, lymphocyte 11%, blasts 9%) and platelets-19 K/uL...
2019: Journal of Community Hospital Internal Medicine Perspectives
Jane Koo, Stacy Silverman, Brandon Nuechterlein, Amy K Keating, Michael R Verneris, Nicholas K Foreman, Jean M Mulcahy Levy
High-dose chemotherapy with autologous hematopoietic stem cell transplantation (autoHSCT) is a well-established treatment for pediatric central nervous system (CNS) tumors. Given the risks of toxicity and infection, pediatric autoHSCT has been historically performed on hospitalized children. As our practice evolved, some patients were transplanted as outpatients. We performed a retrospective cohort analysis of 37 patients who received 90 transplant procedures (49 outpatient and 41 inpatient) at Children's Hospital Colorado...
February 19, 2019: Bone Marrow Transplantation
Louis S Matza, Kristen A Deger, Timothy A Howell, Kimberly Koetter, Andrew M Yeager, Donna Hogge, Vicki Fisher, Arthur C Louie, Karen C Chung
Aims Acute myeloid leukemia (AML) treatment typically involves remission induction chemotherapy followed by consolidation chemotherapy. New treatments for AML have recently been introduced, including a chemotherapy formulation called CPX-351, which is administered via less time-intensive IV infusion than the standard "7 + 3" continuous infusion regimen of cytarabine plus an anthracycline. The purpose of this study was to estimate utilities that could be used in economic modeling of AML treatment...
February 18, 2019: Journal of Medical Economics
Chikara Ebisui, Noriyuki Yamamura, Takayuki Minoji, Hiroyuki Takabatake, Koki Tamai, Tomohiro Kitahara, Noriyuki Watanabe, Shu Okamura, Nariaki Fukuchi, Hideoki Yokouchi, Masakatsu Kinuta, Kazuhito Ohishi
An 82-year-oldwoman was admittedto our hospital because of appetite loss andwas diagnosedwith a Type 3 tumor in the lower gastric body. Pathological examination suggested moderately differentiated adenocarcinoma with negative staining for HER2 by immunohistochemistry. An abdominal CT revealedthickening of the gastric wall andparaaortic lymph node metastases. The clinical findings suggested Stage Ⅳ disease(T4aN3M1). Chemotherapy was administered with a combination of S-1 plus oxaliplatin(SOX). After 2 courses of the SOX regimen, an abdominal CT showed a reduction of the paraaor- tic lymph node metastases, and the CEA level hadd ecreasedto 6...
January 2019: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Derek Weycker, Mark Hatfield, Aaron Grossman, Ahuva Hanau, Alex Lonshteyn, Anjali Sharma, David Chandler
BACKGROUND: Chemotherapy-induced thrombocytopenia (CIT) is a potentially serious complication that can lead to chemotherapy dose delays, dose reductions, or discontinuation, and increases the risk of serious bleeding events. The objectives of this study were to characterize the incidence, clinical consequences, and economic costs of CIT in current US clinical practice. METHODS: A retrospective cohort design and data from two US private healthcare claims repositories (01/2010-12/2016) were employed...
February 14, 2019: BMC Cancer
Margrethe Langer Bro, Christoffer Johansen, Peter Vuust, Lisbeth Enggaard, Bodil Himmelstrup, Torben Mourits-Andersen, Peter Brown, Francesco d'Amore, Elisabeth Anne Wreford Andersen, Niels Abildgaard, Jeppe Gram
PURPOSE: Chemotherapy is associated with both somatic and psychological side effects. Music might ease these problems. Several randomized controlled trials have investigated the effect of music, but the results are inconclusive. We aimed to examine whether live or pre-recorded music listening decreases anxiety during chemotherapy in newly diagnosed lymphoma patients. METHODS: A total of 143 patients with non-Hodgkin and Hodgkin lymphomas were randomly assigned into three groups receiving either 30 min of patient-preferred live music (n = 47), 30 min of patient-preferred pre-recorded music (n = 47), or standard care (n = 49) during up to five outpatient chemotherapy sessions...
February 14, 2019: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Abby Alpert, Mireille Jacobson
Prescription drug shortages began to increase markedly in the mid-2000s, including sterile injectable products such as chemotherapy drugs. Using Medicare claims linked to Surveillance Epidemiology and End Results (SEER), we examined outpatient chemotherapy use during shortage periods relative to the months before and after a shortage for newly diagnosed patients with breast, colorectal, leukemia, lung, lymphoma, ovarian or pancreatic cancer (N=182,470). For most drugs, we found little impact of shortages on either the fraction of patients receiving that drug or the quantity provided...
February 10, 2019: Clinical Pharmacology and Therapeutics
Edgar G Ordóñez-Rubiano, Francisco A Valderrama-Arias, Jonathan A Forbes, Jason M Johnson, Iyan Younus, Jorge H Marín-Muñoz, Mariana Sánchez-Montaño, Diego A Angulo, Hernando A Cifuentes-Lobelo, William Cortes-Lozano, Maria C Pedraza-Ciro, May Leonardo Bello-Dávila, Javier G Patiño-Gómez, Edgar G Ordóñez-Mora
OBJECT: Diffusion tensor imaging (DTI) tractography provides useful information that can be used to optimize surgical planning and help avoid injury during subcortical dissection of eloquent tracts. The objective is to provide a safe, timely, and affordable algorithm for pre-operative DTI language reconstruction for intrinsic frontotemporal pathologies. METHODS: The authors reviewed a prospectively acquired database of pre-operative DTI reconstruction for resection of left frontotemporal lesions over three years at Hospital de San José and Hospital Infantil Universitario San José, Fundación Universitaria de Ciencias de la Salud (FUCS), Bogota, Colombia...
February 5, 2019: World Neurosurgery
Emma Leitinger, Lisa Hui, Andrew Grigg
While proton pump inhibitors (PPIs) are widely prescribed as prophylaxis in selected haematology inpatient and outpatients , an informal survey of haematology units around Australia found wide variations in the specific indications for their use. This is consistent with a literature review which showed a paucity of robust evidence to support their use, specifically in chemotherapy-induced mucositis, thrombocytopenia or administration of high dose glucocorticosteroids in the absence of additional risk factors...
February 5, 2019: Internal Medicine Journal
Hiroko Komatsu, Kaori Yagasaki, Kenro Hirata, Yasuo Hamamoto
PURPOSE: The objective of this qualitative study was to understand the perceived needs of advanced-stage cancer patients with chemotherapy-related hand-foot syndrome (HFS) and/or targeted therapy-related hand-foot skin reaction (HFSR). METHOD: Face-to-face interviews were conducted with 20 outpatients with advanced/recurrent cancer and chemotherapy-related HFS and/or targeted therapy-related HFSR using a semi-structured interview guide at Keio University Hospital, Tokyo, Japan...
February 2019: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
Alex C Cheng, Mia A Levy
PURPOSE: Patients with breast cancer spend a large amount of time and effort receiving treatment. When the number of health care tasks exceeds a patient's ability to manage that workload, they could become overburdened, leading to decreased plan adherence. We used electronic health record data to retrospectively assess dimensions of treatment workload related to outpatient encounters, commuting, and admissions. METHODS: Using tumor registry and scheduling data, we evaluated the sensitivity of treatment workload measures to detect expected differences in breast cancer treatment burden by stage...
February 2019: JCO Clinical Cancer Informatics
Ashraf Fouda, Shaimaa Kandil, Gihad Hamid, Khadijah Boujettif, Mohamed Mahfouz, Mohamed Abdelaziz
INTRODUCTION: Thymic regrowth after chemotherapy treatment has been reported in children with lymphoma, and in order to avoid misdiagnosing these cases as relapses, physicians should become familiar with rebound (reactive) thymic hyperplasia (RTH) and remain aware of its possible occurrence. We aimed to estimate the prevalence of RTH in children with lymphoma after completion of chemotherapy and to evaluate the clinical characteristics, outcomes, and the findings of computed tomography (CT) and gallium-67 (GA-67) scans in these patients...
January 31, 2019: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
Eliana Stein, Meera Rayar, Upasana Krishnadev, Abha Gupta, Shannon Hyslop, Erin Plenert, Tal Schechter-Finkelstein, Lillian Sung
PURPOSE: Pediatric cancer patients experience symptoms that negatively impact quality of life; yoga may be an effective intervention. The primary objective was to determine the feasibility of a 10-week, weekly individualized yoga intervention for children and adolescents receiving outpatient cancer therapy primarily delivered remotely using Skype. Secondary objectives were to describe depression, anxiety, anger, fatigue, quality of life, and symptoms at 5 and 10 weeks after enrollment...
February 2, 2019: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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