keyword
Keywords thyroid OR hyperthyroidism OR ...

thyroid OR hyperthyroidism OR hypothyroidism

https://read.qxmd.com/read/38533382/alteration-in-gut-microbiota-is-associated-with-immune-imbalance-in-graves-disease
#21
JOURNAL ARTICLE
Yalei Liu, Shasha Tang, Yu Feng, Binghua Xue, Chaofei Cheng, Yong Su, Wei Wei, Lijun Zhang, Zhoufeng Huang, Xiaoyang Shi, Yuanyuan Fang, Junpeng Yang, Yun Zhang, Xinru Deng, Limin Wang, Hongyan Ren, Chongjian Wang, Huijuan Yuan
BACKGROUND: Graves' disease (GD), characterized by immune aberration, is associated with gut dysbiosis. Despite the growing interest, substantial evidence detailing the precise impact of gut microbiota on GD's autoimmune processes remains exceedingly rare. OBJECTIVE: This study was designed to investigate the influence of gut microbiota on immune dysregulation in GD. METHODS: It encompassed 52 GD patients and 45 healthy controls (HCs), employing flow cytometry and enzyme-linked immunosorbent assay to examine lymphocyte and cytokine profiles, alongside lipopolysaccharide (LPS) levels...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38533378/incidence-and-risk-factors-for-cancer-in-people-with-type-1-diabetes-stratified-by-stages-of-diabetic-kidney-disease-a-nationwide-finnish-cohort-study
#22
JOURNAL ARTICLE
Maija Feodoroff, Valma Harjutsalo, Sari Mäkimattila, Per-Henrik Groop
BACKGROUND: Individuals with type 1 diabetes (T1D) have been reported to have increased overall risk of cancer. In addition, individuals with a kidney transplant/transplantation (KT) have markedly increased cancer risk due to chronic use of immunosuppressive agents. However, it has not been elucidated whether the observed excess cancer risk is related to KT or whether diabetic kidney disease (DKD) per se is a risk factor for cancer in individuals with T1D. METHODS: The study included 5035 individuals from the Finnish Diabetic Nephropathy Study (FinnDiane) and 14,061 control individuals without diabetes...
May 2024: The Lancet regional health. Europe
https://read.qxmd.com/read/38533287/role-of-genetic-testing-in-the-management-of-indeterminate-thyroid-nodules-in-the-indian-setting
#23
REVIEW
Jeyashanth Riju, Nihal Thomas, Thomas V Paul, Deepak Thomas Abraham, Rekha Pai, Anne J Prabhu, Paul Mazhuvanchary Jacob, Remya Rajan, Rajiv C Michael, Amit Jiwan Tirkey, Natarajan Ramalingam, Hesarghatta S Asha, Nitin Kapoor
The increased detection of thyroid nodules in the human population has led to an increase in the number of thyroid surgeries without an improvement in survival outcomes. Though the choice for surgery is straightforward in malignant thyroid nodules, the decision is far more complex in those nodules that get categorized into indeterminate thyroid nodules (ITN) by fine needle aspiration. Therefore, there is a pressing need to develop a tool that will aid in decision-making among the ITN. In this context, the development of various molecular testing (MT) panels has helped to confirm or rule out malignancy, reducing unnecessary surgeries and potentially guiding the extent of surgery as well...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38533284/utility-of-colour-flow-doppler-ultrasonography-to-differentiate-gestational-transient-thyrotoxicosis-and-graves-disease-in-pregnancy
#24
JOURNAL ARTICLE
Vijay Sheker Reddy Danda, Piyush Lodha, Srinivas Rao Paidipally, Sandeep Reddy Devireddy
INTRODUCTION: Accurate diagnosis of the etiology of thyrotoxicosis in pregnancy is important to guide appropriate treatment. The role of thyroid blood flow velocities by color Doppler to differentiate between Graves' disease (GD) in pregnancy and gestational transient thyrotoxicosis (GTT) is not well explored. This study evaluated inferior thyroid artery (ITA)-peak systolic velocity (PSV) as a marker for differential diagnosis of thyrotoxicosis in pregnancy. METHODS: Fifty-six pregnant patients with thyrotoxicosis (30 with GTT and 26 with GD) along with 30 age-matched healthy euthyroid pregnant subjects were enrolled...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38533278/prevalence-of-congenital-hypothyroidism-in-india-mapping-and-critical-appraisal
#25
JOURNAL ARTICLE
Vijaya Sarathi, Siddu Nikith
No abstract text is available yet for this article.
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38532901/a-6-year-old-with-childhood-absence-epilepsy-and-motor-hyperactivity
#26
JOURNAL ARTICLE
Stéphane Auvin
A case study of a child with childhood absence epilepsy and hyperactivity introduces the discussion around the psychiatric diagnosis, differential considerations, and pharmacologic treatment options for ADHD/hyperactivity in children with epilepsy. Most of the time, ADHD in children with epilepsy is an inattentive form. The assessment emphasizes the need to differentiate ADHD symptoms from other psychiatric comorbidities. This is also crucial to evaluate when symptoms emerged, their impact on daily life, and if it could be a potential medication side effect...
2024: Epilepsy & behavior reports
https://read.qxmd.com/read/38532782/identification-of-a-novel-non-v600e-braf-mutation-in-papillary-thyroid-cancer
#27
Marco Capezzone, Maja Rossi, Elisabetta Macerola, Silvia Cantara, Francesco Pepe, Eugenia Maria Morabito, Gilda Dalmazio, Sara Bardi, Agostino Ognibene, Massimo Alessandri, Gabriele Materazzi, Luigi De Napoli, Michele Cirianni, Liborio Torregrossa
Papillary thyroid cancer (PTC) is a common endocrine malignancy, and its incidence is reported to be constantly increasing. BRAF mutation is detected in approximately 44% of PTCs, and the most common BRAF mutation is thymine (T) to adenine (A) missense mutation in nucleotide 1796 (T1796A, V600E). Although BRAFV600E represents 95% of all BRAF mutations, uncommon BRAF mutations have been reported in thyroid carcinomas and represent an alternative mechanism of BRAF activation with unclear clinical significance...
2024: Case Reports in Endocrinology
https://read.qxmd.com/read/38532754/cutaneous-implantation-metastasis-of-papillary-thyroid-carcinoma-a-caveat-of-fine-needle-aspiration
#28
Yotsapon Thewjitcharoen, Egkaluck Wanothayaroj, Veekij Veerasomboonsin
No abstract text is available yet for this article.
March 2024: Oxford Medical Case Reports
https://read.qxmd.com/read/38532506/sonographic-characteristics-of-diffuse-sclerosing-variant-of-papillary-thyroid-carcinoma-with-histopathological-correlation-a-preliminary-study
#29
JOURNAL ARTICLE
Wanying Li, Ying Wang, Luying Gao, Ruie Feng, Ke Lv, Xining Wu, Xiao Yang, Sheng Cai, Hongyan Wang, Jianchu Li
BACKGROUND: Diffuse sclerosing variant of papillary thyroid carcinoma (DSVPTC) is a rare but high invasive subtype of papillary thyroid carcinoma, which mandates an aggressive clinical strategy. Few studies have focused on the sonographic characteristics of DSVPTC and the role of ultrasound in diagnosis and treatment of this variant remains unknown. This study aimed to identify and understand DSVPTC more accurately under ultrasound in correlation with pathology. METHODS: The ultrasound characteristics and histopathologic sections of 10 lesions in 10 DSVPTC patients who underwent thyroid surgery at our center between 2014 and 2020 were reviewed and compared with 184 lesions in 168 classic variant of papillary thyroid carcinoma (cPTC) patients...
March 26, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38532265/clinical-and-magnetic-resonance-imaging-findings-in-a-french-bulldog-puppy-with-genetically-confirmed-congenital-hypothyroidism
#30
Katia Sánchez González, Harry Warwick, Marius Conradie, Neringa Alisauskaite
A 7-month-old male French bulldog was referred for abnormal mentation and gait. Physical examination revealed a dome shaped calvarium and persistent bregmatic fontanelle. Neurological examination revealed proprioceptive ataxia, pelvic limb paraparesis and strabismus with moderate ventriculomegaly, thinning of the cerebral parenchyma, and widened cerebral sulci on magnetic resonance imaging. Masses were identified in the region of the thyroid, which appeared heterogeneous and hyperintense in T1-weighted and T2-weighted compared with the adjacent muscle signal masses were identified...
March 26, 2024: Journal of Veterinary Internal Medicine
https://read.qxmd.com/read/38532234/stigma-risks-and-benefits-of-medicinal-cannabis-use-among-australians-with-cancer
#31
JOURNAL ARTICLE
Julia N Morris, Jessica Loyer, Jason Blunt
PURPOSE: People with cancer who use medicinal cannabis do so despite risks associated with limited clinical evidence, legalities, and stigma. This study investigated how Australians with cancer rationalise their medicinal cannabis use despite its risks. METHODS: Ten adults (5 males and 5 females; mean age of 53.3) who used cannabis medicinally for their cancer were interviewed in 2021-2022 about how they used and accessed the substance, attitudes and beliefs underpinning their use, and conversations with others about medicinal cannabis...
March 27, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38531903/cancer-incidence-trends-in-new-york-state-and-associations-with-common-population-level-exposures-2010-2018-an-ecological-study
#32
JOURNAL ARTICLE
Haokun Yuan, Rebecca D Kehm, Josephine M Daaboul, Susan E Lloyd, Jasmine A McDonald, Lina Mu, Parisa Tehranifar, Kai Zhang, Mary Beth Terry, Wan Yang
The impact of common environmental exposures in combinations with socioeconomic and lifestyle factors on cancer development, particularly for young adults, remains understudied. Here, we leveraged environmental and cancer incidence data collected in New York State at the county level to examine the association between 31 exposures and 10 common cancers (i.e., lung and bronchus, thyroid, colorectal, kidney and renal pelvis, melanoma, non-Hodgkin lymphoma, and leukemia for both sexes; corpus uteri and female breast cancer; prostate cancer), for three age groups (25-49, 50-69, and 70-84 year-olds)...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531895/regulation-of-hypothalamic-reactive-oxygen-species-and-feeding-behavior-by-phosphorylation-of-the-beta-2-thyroid-hormone-receptor-isoform
#33
JOURNAL ARTICLE
Svetlana Minakhina, Sun Young Kim, Fredric E Wondisford
Unlike other thyroid hormone receptors (THRs), the beta 2 isoform (THRB2) has a restricted expression pattern and is uniquely and abundantly phosphorylated at a conserved serine residue S101 (S102 in humans). Using tagged and or phosphorylation-defective (S101A) THRB2 mutant mice, we show that THRB2 is present in a large subset of POMC neurons and mitigates ROS accumulation during ROS-triggering events, such as fasting/refeeding or high fat diet (HFD). Excessive ROS accumulation in mutant POMC neurons was accompanied by a skewed production of orexigenic/anorexigenic hormones, resulting in elevated food intake...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531501/effects-of-moderate-ethanol-exposure-on-risk-factors-for-cardiovascular-disease-and-colorectal-cancer-in-adult-wistar-rats
#34
JOURNAL ARTICLE
Anna J Kwon, Lani Morales, Louise Chatagnier, Jacqueline Quigley, Jeremy Pascua, Natalie Pinkowski, Susan M Brasser, Mee Young Hong
While past studies have provided evidence linking excessive alcohol consumption to increased risk for cardiovascular diseases (CVDs) and colorectal cancer (CRC), existing data on the effects of moderate alcohol use on these conditions have produced mixed results. The purpose of this study was to investigate the effects of moderate alcohol consumption on risk factors associated with the development of CVDs and CRC in adult rats. Twenty-four, 14-month-old, non-deprived male Wistar rats were randomly assigned to either an ethanol group, which consisted of voluntary access to a 20% (v/v) ethanol solution on alternate days, or a water control group (n = 12/group) for 13 weeks...
March 24, 2024: Alcohol
https://read.qxmd.com/read/38531109/evaluating-potential-developmental-toxicity-of-perfluoroalkyl-and-polyfluoroalkyl-substances-in-xenopus-laevis-embryos-and-larvae
#35
JOURNAL ARTICLE
Sigmund J Degitz, Philip P Degoey, Jonathan T Haselman, Jennifer H Olker, Emma H Stacy, Chad Blanksma, Scott Meyer, Kali Z Mattingly, Brett Blackwell, Anne S Opseth, Michael W Hornung
As part of the US Environmental Protection Agency's perfluoroalkyl and polyfluoroalkyl substances (PFAS) Action Plan, the agency is committed to increasing our understanding of the potential ecological effects of PFAS. The objective of these studies was to examine the developmental toxicity of PFAS using the laboratory model amphibian species Xenopus laevis. We had two primary aims: (1) to understand the developmental toxicity of a structurally diverse set of PFAS compounds in developing embryos and (2) to characterize the potential impacts of perfluorooctanesulfonic acid (PFOS), perfluorohexanesulfonic acid (PFHxS), perfluorooctanoic acid (PFOA), and hexafluoropropylene oxide-dimer acid (HFPO-DA a...
March 26, 2024: Journal of Applied Toxicology: JAT
https://read.qxmd.com/read/38530620/sodium-glucose-cotransporter-2-inhibitors-and-cancer-a-systematic-review-and-meta-analysis
#36
JOURNAL ARTICLE
B Xu, B Kang, S Li, S Fan, J Zhou
BACKGROUND: The effect of sodium-glucose cotransporter 2 (SGLT2) inhibitors on cancer has yet to be fully elucidated. OBJECTIVE: This systematic review and meta-analysis investigated the effects of SGLT2 inhibitors on cancer. METHODS: We searched the PubMed and ClinicalTrials.gov databases up to July 15, 2023, to identify eligible randomized, double-blind, placebo-controlled trials that lasted at least ≥24 weeks. The primary outcome was the overall cancer incidence, and the secondary outcomes were the incidences of various types of cancer...
March 26, 2024: Journal of Endocrinological Investigation
https://read.qxmd.com/read/38530608/characteristics-and-risk-factors-of-cervical-lymph-node-metastasis-in-cn0-papillary-thyroid-microcarcinoma-of-the-isthmus
#37
JOURNAL ARTICLE
Linjie Ma
The surgical resection range of papillary thyroid microcarcinoma of the isthmus (PTMCI) is controversial, and the guidelines do not fully guide the central lymph node dissection (CLND).We retrospectively studied the comparison of PTMCI (Group A, n = 65 cases) and non-PTMCI (Group B, n = 80 cases). Based on whether central lymph node metastasis (CLNM) was further detected, they were further divided into the PTMCI with CLNM (group C, n = 42 cases), the PTMCI without CLNM (group D, n = 23 cases), the non-PTMCI with CLNM (group E, n = 45 cases), the non-PTMCI without CLNM (group F, n = 35 cases)...
March 26, 2024: Updates in Surgery
https://read.qxmd.com/read/38530419/triiodothyronine-supplementation-for-children-undergoing-cardiopulmonary-bypass-a-meta-analysis
#38
JOURNAL ARTICLE
Monique R Radman, April E Slee, Eva M Marwali, Michael A Portman
Specific pediatric populations have exhibited disparate responses to triiodothyronine (T3) repletion during and after cardiopulmonary bypass (CPB). Objective: To determine if T3 supplementation improves outcomes in children undergoing CPB. We searched randomized controlled trials (RCT) evaluating T3 supplementation in children aged 0-3 years undergoing CPB between 1/1/2000 and 1/31/2022. We calculated Hazard ratios (HR) for time to extubation (TTE), ICU length of stay (LOS), and hospital LOS. 5 RCTs met inclusion criteria with available patient-level data...
March 26, 2024: Pediatric Cardiology
https://read.qxmd.com/read/38529838/new-reference-values-for-thyroid-volume-by-ultrasound-in-german-children-and-adolescents-from-a-population-based-study
#39
JOURNAL ARTICLE
Raphael Hirtz, Roma Thamm, Ronny Kuhnert, Klaus-Peter Liesenkötter, Michael Thamm, Corinna Grasemann
CONTEXT: Reliable reference values for thyroid ultrasound measurements are essential to effectively guide individual diagnostics and direct health care measures at the population level, such as iodine fortification programs. However, the latest reference values for total thyroid volume (Tvol) provided by the WHO in 2004 only apply to the 6 to 12-year-old age group and are limited to countries with a long history of iodine sufficiency, which does not reflect the situation in most European countries, including Germany...
March 26, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38529769/dosimetry-during-iodine-131-therapy-a-technical-point-of-view-from-a-single-centre-s-own-experience
#40
JOURNAL ARTICLE
Wioletta Chalewska, Paulina Cegla, Anna Moczulska, Edyta Strzemecka, Agata Sackiewicz, Marek Dedecjus
BACKGROUND: Nuclear medicine uses radionuclides in medicine for diagnosis, staging, therapy, and monitoring the response to therapy. The application of radiopharmaceutical therapy for the treatment of certain diseases is well-established, and the field is expanding. Internal dosimetry is multifaceted and includes different workflows, as well as various calculations based on patient- specific dosimetry. AIM: The objective of this study was to introduce the technical issues which might occur during iodine-131 (¹³¹I) dosimetry performed in nuclear medicine departments...
2024: Nuclear Medicine Review. Central & Eastern Europe
keyword
keyword
162205
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.