keyword
https://read.qxmd.com/read/38531107/tuberculosis-in-united-states-bound-follow-to-join-asylees-2014-2019
#1
JOURNAL ARTICLE
Yecai Liu, Drew L Posey, Michelle S Weinberg, Christina R Phares
Persons may seek asylum in the United States or at a U.S. port of entry. Principal asylees are those who are granted asylum status. Their spouse and unmarried children under 21 years of age may be granted asylum if accompanying, or following to join, the principal asylees. U.S.-bound follow-to-join asylees must undergo an overseas medical examination that includes tuberculosis (TB) screening. Culture-based overseas TB screening in U.S.-bound follow-to-join asylees has not been evaluated. We evaluated data from overseas TB screening in 19,088 arrivals of follow-to-join asylees during 2014-2019 and assessed data from their postarrival evaluation, which is recommended for those at risk for TB...
March 26, 2024: American Journal of Tropical Medicine and Hygiene
https://read.qxmd.com/read/38521643/a-review-of-host-specific-diagnostic-and-surrogate-biomarkers-in-children-with-pulmonary-tuberculosis
#2
REVIEW
Junaid Shaik, Manormoney Pillay, Prakash Jeena
BACKGROUND: Tuberculosis (TB) is one of the most common causes of mortality globally with a steady rise in paediatric cases in the past decade. Laboratory methods of diagnosing TB and monitoring response to treatment have limitations. Current research focuses on interrogating host- and/or pathogen-specific biomarkers to address this problem. METHODS: We reviewed the literature on host-specific biomarkers in TB to determine their value in diagnosis and treatment response in TB infected and HIV/TB co-infected children on anti-tuberculosis treatment...
February 17, 2024: Paediatric Respiratory Reviews
https://read.qxmd.com/read/38504680/suboptimal-child-healthcare-practices-and-the-development-of-multiple-infectious-diseases-in-children-aged-24-59%C3%A2-months
#3
JOURNAL ARTICLE
Ning Sulistiyowati, Dwi Hapsari Tjandrarini, Christiana Rialine Titaley, Bertha J Que, Puti Sari Hidayangsih, Suparmi, Sudikno Sudikno, Yuni Purwatiningsih, Lely Indrawati, Selma Siahaan, Windy Pradita Adyarani
BACKGROUND: Infections continue to be a major cause of death among children under the age of five worldwide. This study aimed to identify the factors associated with the development of multiple infectious diseases in children aged 24-59 months in Indonesia. METHODS: Data from the 2018 Basic Health Research conducted by the Ministry of Health, Republic of Indonesia, were used. Information from 39,948 children aged 24-59 months was analyzed. The outcome variable was the development of multiple infectious diseases, that is, acute respiratory infections, pneumonia, pulmonary tuberculosis, diarrhea, and hepatitis, in the month before the survey...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38465108/migrant-pathology-screening-in-the-pediatric-population-a-five-year-retrospective-study-from-a-level-ii-hospital
#4
JOURNAL ARTICLE
Luísa Castello-Branco Ribeiro, Filipa Paixão, Francisca Costa, Paula Correia
INTRODUCTION: The migrant population residing in Portugal has been growing. In 2015, the pediatrics department at Professor Doutor Fernando Fonseca Hospital, a level II hospital, implemented a screening for endemic pathologies in asymptomatic migrant children to enable their timely diagnosis and treatment. This study aimed to identify and characterize the main findings in the migrant pathology screening. METHODS: This was a retrospective and descriptive study of asymptomatic children and adolescents who underwent opportunistic screening for migrant pathology in a hospital setting between January 2016 and April 2021...
February 2024: Curēus
https://read.qxmd.com/read/38439124/survey-of-the-present-health-nutritional-status-of-shompen-tribe-of-great-nicobar-island
#5
JOURNAL ARTICLE
Paluru Vijayachari, S Awaradi, H M Siddaraju, K Nithin, S S Veerendra, U Suresh Babu, M Punnam Chander, C Kartick, M Anwesh, A P Sugunan
BACKGROUND OBJECTIVES: Shompens are one of the two mongoloid tribes of Nicobar district. There is little information about their recent health status since the last survey which was conducted in 1998. Hence, a comprehensive health and nutritional survey was conducted in March 2017 to assess the changes. The survey was carried out by a joint team of various organizations including the ICMR-Regional Medical Research Centre and Tribal Welfare and Health Department both located in Port Blair...
January 1, 2024: Indian Journal of Medical Research
https://read.qxmd.com/read/38423021/effect-of-bcg-vaccination-against-mycobacterium-tuberculosis-infection-in-adult-brazilian-health-care-workers-a-nested-clinical-trial
#6
JOURNAL ARTICLE
Paulo Cesar Pereira Dos Santos, Nicole Louise Messina, Roberto Dias de Oliveira, Patricia Vieira da Silva, Marco Antonio Moreira Puga, Margareth Dalcolmo, Glauce Dos Santos, Marcus Vinícius Guimarães de Lacerda, Bruno Araújo Jardim, Fernando Fonseca de Almeida E Val, Nigel Curtis, Jason R Andrews, Julio Croda
BACKGROUND: The effectiveness of BCG vaccine for adult pulmonary tuberculosis remains uncertain. In this study, we aimed to evaluate the effect of vaccination with BCG-Denmark to prevent initial and sustained interferon-γ release assay conversion in Brazilian health-care workers. METHODS: This substudy is a nested randomised controlled trial embedded within the BRACE trial (NCT04327206). Specifically, this substudy enrolled Brazilian health-care workers (aged ≥18 years) from three sites in Brazil (Manaus, Campo Grande, and Rio de Janeiro) irrespective of previously receiving BCG vaccination...
February 26, 2024: Lancet Infectious Diseases
https://read.qxmd.com/read/38405015/assessment-of-factors-associated-with-anti-tubercular-treatment-compliance-in-children-a-cross-sectional-study
#7
JOURNAL ARTICLE
Lihong Gao, Biru Luo
Objective. This study aims to investigate compliance and the influencing factors related to pediatric tuberculosis patients who are undergoing treatment with anti-tuberculosis drugs in the Sichuan Province of China. Methods. A questionnaire survey was conducted between March 2019 and March 2021. The survey was distributed to caregivers of children aged 0 to 14 who had been diagnosed with pulmonary tuberculosis. These children had been receiving oral anti-tuberculosis drug treatment for more than 1 month...
2024: Global Pediatric Health
https://read.qxmd.com/read/38390338/il-27-alters-inflammatory-cytokine-expression-and-limits-protective-immunity-against-mycobacterium-tuberculosis-in-a-neonatal-bcg-vaccination-model
#8
JOURNAL ARTICLE
Shelby D Bradford, Kenneth J Ryan, Ashley M Divens, Jessica M Povroznik, Sunilkanth Bonigala, Cory M Robinson
BACKGROUND: Efforts to control tuberculosis (TB), caused by the pathogen Mycobacterium tuberculosis (Mtb), have been hampered by the immense variability in protection from BCG vaccination. While BCG protects young children from some forms of TB disease, long-term protection against pulmonary disease is more limited, suggesting a poor memory response. New vaccines or vaccination strategies are required to have a realistic chance of eliminating TB disease. In TB endemic areas, routine immunization occurs during the neonatal period and as such, we hypothesized that inadequate protective immunity elicited by BCG vaccination could be the result of the unique early-life immune landscape...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38377462/disseminated-mycobacterial-infection-with-reactive-polyarthritis-poncet-s-disease-during-immune-suppressive-treatment-including-ustekinumab-for-pediatric-crohn-s-disease
#9
JOURNAL ARTICLE
Chiara Minotti, Paola Costenaro, Daniele Donà, Monica Zuliani, Luca Bosa, Alberta Leon, Giorgio Perilongo, Paola Gaio, Giorgia Martini, Mara Cananzi
BACKGROUND: The incidence of pediatric inflammatory bowel disease is increasing. tumor necrosis factor alpha inhibitors medicines improved the prognosis of affected subjects. Nonetheless, a proportion of patients do not respond or lose response to treatment. Newer biologics, like ustekinumab, have been approved for adults. The pediatric off-label use of these drugs is increasing, despite limited safety evidence. We report a case of disseminated mycobacterial infection (MI) presenting with reactive polyarthritis (Poncet's disease, PD) in a girl with Crohn's disease receiving various immunosuppressants, including ustekinumab...
February 20, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38351896/clinical-immunological-and-genetic-description-of-a-mexican-cohort-of-patients-with-dock8-deficiency
#10
JOURNAL ARTICLE
Eduardo Liquidano-Perez, Gibert Maza-Ramos, Bethy Alexandra Perez Arias, Saul Oswaldo Lugo Reyes, Tania Barragan Arevalo, Sara Alejandra Solorzano-Morales, Edna Venegas Montoya, Aidé Tamara Staines-Boone, Rogelio Guzmán Cotaya, Satoshi Okada, Capucine Picard, Etienne Patin, Nideshda Ramirez-Uribe, Juan Carlos Bustamante-Ogando, Selma Cecilia Scheffler-Mendoza, Marco Antonio Yamazaki-Nakashimada, Marimar Saez-de-Ocariz, Sara Elva Espinosa Padilla, Maria Edith Gonzalez-Serrano
PURPOSE: We aimed to describe the clinical, immunological, and genetic features of patients with DOCK8 deficiency (DOCK8-Def) in a tertiary care center for children. METHODS: Retrospective chart review of patients' clinical, immunological, and genetic characteristics with DOCK8-Def. Genetic analysis was performed with targeted- or whole-exome sequencing; we also assessed DOCK8 protein expression and a lymphoproliferation assay and analyzed survival by the Kaplan-Meier method...
February 2024: Pediatric Allergy and Immunology
https://read.qxmd.com/read/38329305/-risk-factors-in-the-delay-of-treatment-of-childhood-tuberculosis-in-a-peruvian-hospital
#11
JOURNAL ARTICLE
Gabriela Cartolin P, Consuelo Luna M
UNLABELLED: Childhood tuberculosis (c-TB) continues to be one of the causes of morbidity and mortality in children, but there is still little information on the delay in the initiation of specific treatment. OBJECTIVE: To determine the risk factors associated with delayed initiation of tuberculosis (TB) treatment in children under 15 years of age. PATIENTS AND METHOD: Case-control study. Patients <15 years of age with a diagnosis of childhood pulmonary tuberculosis (c-PTB) with delayed treatment initiation >24 hours were included...
December 2023: Andes pediatrica: revista Chilena de pediatría
https://read.qxmd.com/read/38328511/re-estimation-of-the-burden-of-serious-fungal-diseases-in-uganda
#12
JOURNAL ARTICLE
Felix Bongomin, Richard Kwizera, Martha Namusobya, Norman van Rhijn, Irene Andia-Biraro, Bruce J Kirenga, David B Meya, David W Denning
BACKGROUND: It is of utmost importance to monitor any change in the epidemiology of fungal diseases that may arise from a change in the number of the at-risk population or the availability of local data. OBJECTIVE: We sought to update the 2015 publication on the incidence and prevalence of serious fungal diseases in Uganda. METHODS: Using the Leading International Fungal Education methodology, we reviewed published data on fungal diseases and drivers of fungal diseases in Uganda...
2024: Therapeutic Advances in Infectious Disease
https://read.qxmd.com/read/38320580/tb-or-not-tb-diagnostic-sensitivity-specifity-and-interobserver-agreement-in-the-radiological-diagnosis-of-pulmonary-tuberculosis-in-children
#13
JOURNAL ARTICLE
Folke Brinkmann, Jana Hofgrefe, Frank Ahrens, Jürgen Weidemann, Lars Daniel Berthold, Nicolaus Schwerk
BACKGROUND: The differentiation between latent tuberculosis infection (LTBI) and tuberculosis (TB) relies on radiological changes. Confirming the diagnosis remains a challenge because typical findings are often missing in children. This study evaluates diagnostic sensitivity, specifity and interobserver agreement on the radiological diagnosis of TB by chest-x-rays in accordance to professional specialization and work experience. METHODS: Chest x-rays of 120 children with proven tuberculosis infection were independently evaluated by general radiologists, paediatric radiologists and paediatric pulmonologists...
February 6, 2024: Klinische Pädiatrie
https://read.qxmd.com/read/38309959/-standard-technical-specifications-for-methacholine-chloride-methacholine-bronchial-challenge-test-2023
#14
JOURNAL ARTICLE
(no author information available yet)
The methacholine challenge test (MCT) is a standard evaluation method of assessing airway hyperresponsiveness (AHR) and its severity, and has significant clinical value in the diagnosis and treatment of bronchial asthma. A consensus working group consisting of experts from the Pulmonary Function and Clinical Respiratory Physiology Committee of the Chinese Association of Chest Physicians, the Task Force for Pulmonary Function of the Chinese Thoracic Society, and the Pulmonary Function Group of Respiratory Branch of the Chinese Geriatric Society jointly developed this consensus...
February 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38309752/pivotal-relationship-between-heavy-metal-pm-2-5-exposures-and-tuberculosis-in-bangladeshi-children-protocol-paper-of-a-case-control-study
#15
JOURNAL ARTICLE
Rehnuma Haque, Molly Hanson, Md Shariful Islam, Nazrin Akter, Mohammad Moniruzzaman, Md Jahangir Alam, Md Kamruzzaman, Mahbubur Rahman, Mohammod Jobayer Chisti, Rubhana Raqib, Syed Moshfiqur Rahman
INTRODUCTION: Air pollution is a global issue that poses a significant threat to public health. Children, due to their developing physiology, are particularly susceptible to the inhalation of environmental pollutants. Exposure can trigger immune modulation and organ damage, increasing susceptibility to respiratory diseases. Therefore, we aim to examine the association between heavy metal and particulate matter exposure with tuberculosis in children. METHODS AND ANALYSIS: As a case-control study, we will include children diagnosed with pulmonary tuberculosis (n=60) and matched healthy controls (n=80) recruited from the same communities in Dhaka, Bangladesh...
February 2, 2024: BMJ Open
https://read.qxmd.com/read/38296384/raised-circulatory-t-regulatory-cells-in-paediatric-tuberculosis-an-environment-for-bacterial-persistence
#16
JOURNAL ARTICLE
Ranjith Kumar, Richa Gupta, Pooja Dewan, Bineeta Kashyap, Mrinalini Kotru
OBJECTIVES: T-regulatory cells (Tregs) restrain the Th1-mediated immune response and thus may help in persistence and dissemination of childhood Tuberculosis. This study compared the percentage of Tregs in peripheral blood of paediatric TB patients (severe and non severe) with healthy individuals by flow cytometry. METHODS: Study enrolled 40 subjects, less than 12 years along with 20 age matched healthy controls. Cases were further classified as severe TB and non severe TB...
January 2024: Indian Journal of Tuberculosis
https://read.qxmd.com/read/38244884/diagnostic-accuracy-of-xpert%C3%A2-mtb-rif-ultra-for-childhood-tuberculosis-in-west-africa-a-multicentre-pragmatic-study
#17
JOURNAL ARTICLE
Awa Ba Diallo, Victory F Edem, Arnauld Fiogbe, Kwabena A Osman, Mohamed Tolofoudie, Amadou Somboro, Bassirou Diarra, Babatunde Ogunbosi, Ibrahim Abok, Augustine O Ebonyi, Bamenla Goka, Dissou Affolabi, Regina Oladokun, Aderemi O Kehinde, Nuredin Mohammed, Toyin Togun
OBJECTIVE: To evaluate the performance of Xpert MTB/RIF Ultra ('Ultra') for diagnosis of childhood tuberculosis (TB) within public health systems. METHODS: In this cross-sectional study, children aged <15 years with presumptive pulmonary TB were consecutively recruited and evaluated for TB at tertiary-level hospitals in Benin, Mali and Ghana. Bivariate random-effects models were used to determine the pooled sensitivity and specificity of Ultra against culture...
January 18, 2024: International Journal of Infectious Diseases: IJID
https://read.qxmd.com/read/38244185/long-term-outcomes-of-survivors-of-covid-19-with-moderate-to-severe-infection-and-children-with-multisystem-inflammatory-syndrome-or-mis-c
#18
JOURNAL ARTICLE
Raman Singla, Jhuma Sankar, Anshula Tayal, Himanshu Bhadani, Narendra K Bagri, Sushil Kabra, Rakesh Lodha
The study aims to evaluate the long-term outcomes - functional, pulmonary and non-pulmonary (other organs) - in children hospitalized with COVID-19 infection or with Multisystem inflammatory syndrome (MIS-C) after 1-2 y of discharge. All children with moderate or severe COVID-19 or MIS-C were enrolled. Out of 45 enrolled subjects, 19.8% had COVID-19 infection and 82% had MIS-C. Four children (8.9%) had abnormal baseline echocardiography; two each with cardiac dysfunction and coronary dilatation...
January 20, 2024: Indian Journal of Pediatrics
https://read.qxmd.com/read/38234744/patterns-of-childhood-tuberculosis-diagnosis-in-ethiopia-a-multicenter-cross-sectional-study
#19
Kedir Usmael, Tsegahun Manyazewal, Hussen Mohammed, Getnet Yimer, Lemessa Oljira, Kedir Teji Roba, Tesfahunegn Hailemariam, Tigist Adjeme, Dagmawit Tesfaye, Haileleul Bisrat, Esther Ngadaya, Yimtubezinash Woldeamanuel
Background Children share 12% of the global 10 million people infected with tuberculosis (TB) each year. Closing case detection gap in children remains difficult, with 56% of all children and 65% under-five with TB missed each year. We aimed to assess the patterns of childhood TB diagnosis and underlying determinants in Ethiopia when different TB diagnostic platforms are applied. Methods A multi-site, cross-sectional study was carried out in Ethiopia as part of the larger EXIT-TB study - evidence-based multiple focused integrated intensified TB screening package...
December 29, 2023: Research Square
https://read.qxmd.com/read/38197102/identifying-immunodeficiency-status-in-children-with-pulmonary-tuberculosis-using-radiomics-approach-based-on-un-enhanced-chest-computed-tomography
#20
JOURNAL ARTICLE
Hao Ding, Xin Chen, Haoru Wang, Li Zhang, Fang Wang, Ling He
BACKGROUND: Children with primary immunodeficiency diseases (PIDs) are particularly vulnerable to infection of Mycobacterium tuberculosis (Mtb). Chest computed tomography (CT) is an important examination diagnosing pulmonary tuberculosis (PTB), and there are some differences between primary immunocompromised and immunocompetent cases with PTB. Therefore, this study aimed to use the radiomics analysis based on un-enhanced CT for identifying immunodeficiency status in children with PTB...
December 26, 2023: Translational Pediatrics
keyword
keyword
162194
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.