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https://read.qxmd.com/read/30747833/medical-assessment-and-triage-of-pediatric-patients-with-anorexia-nervosa-in-primary-care
#1
Kendra J Homan, Leslie A Sim, Susan L Crowley, Jocelyn R Lebow, Lisa N Kransdorf
OBJECTIVE: To examine the medical assessment and triage of pediatric patients with anorexia nervosa (AN) initially seen in primary care. METHODS: A retrospective cohort study was conducted for all pediatric patients with AN who had eating/weight concerns and initially identified symptoms in primary care in a single health care system between January 1, 2010, and December 31, 2016. Information on presenting concern, medical assessment/laboratory tests, clinical diagnoses, treatment recommendations, and referrals were abstracted from the medical record...
February 2019: Journal of Developmental and Behavioral Pediatrics: JDBP
https://read.qxmd.com/read/30738149/an-imaging-protocol-to-discriminate-specialized-conduction-tissue-during-congenital-heart-surgery
#2
Abhijit Mondal, John Lackey, Mossab Saeed, Fei-Yi Wu, Jordan Johnson, Chao Huang, Frank Sachse, Robert Hitchcock, Aditya Kaza
OBJECTIVES: We performed preclinical validation of intraoperative fiber-optic confocal microscopy (FCM) and assessed its safety and efficacy in an ovine model of the pediatric heart. METHODS: Intraoperative imaging was performed using an FCM system (Cellvizio, Mauna Kea Technology, Paris, France) with specialized imaging miniprobe (GastroFlex UHD, Mauna Kea Technologies). Before imaging, we applied an extracellular fluorophore, sodium fluorescein, to fluorescently label extracellular space...
February 6, 2019: Seminars in Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/30695882/-clinical-analysis-of-right-atrial-appendage-aneurysms-complicated-by-atrial-tachyarrhythmias-in-three-children
#3
Y Zhang, X M Li, H Jiang, F Q Zhang, Y Q Jin, H J Liu, H Y Ge
Objective: To investigate the clinical features and results of treatment for right atrial appendage aneurysms complicated by atrial tachyarrhythmias in children. Methods: This retrospective study included three children with right atrial appendage aneurysm complicated by atrial tachyarrhythmias (aged 1.0 to 5.3 years, weight 10 to 17.1 kg) who were hospitalized at the Pediatric Cardiology Department (Heart Center) of the First Hospital of Tsinghua University (Beijing Huaxin Hospital) during the period from January 2016 through April 2018...
February 2, 2019: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/30695881/-relationship-between-blood-pressure-variability-and-target-organ-damage-in-children-with-essential-hypertension
#4
Y Liu, L Shi, Y Lin, T Zheng, X H Li, Y Y Liu, J J Liu, D Liu
Objective: To investigate the correlation between blood pressure variability (BPV) and target organ damage in children with essential hypertension. Methods: A retrospective review identified 144 children (104 boys (72.2%) and 40 girls (27.8%), age (11.7±2.5)years) diagnosed with essential hypertension at Children's Hospital Affiliated to Capital Institute of Pediatrics from January 2013 to June 2018. Data on indicators for assessing fundus, cardiac, and renal damages obtained included 24-hour ambulatory blood pressure monitoring, BPV, fundus oculi examination, electrocardiogram, echocardiography, renal function, 24-hour urine protein quantitation, urine microalbumin, serum and urine β(2)-microglobulin...
February 2, 2019: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/30669920/chomping-at-the-bit-a-descriptive-report-on-pediatric-clenbuterol-ingestion
#5
Jordan Woolum, Nicholas Mancuso, Philip W Rutter, Regan A Baum, Peter Akpunonu
INTRODUCTION: Clenbuterol hydrochloride is a selective beta-2 adrenergic agonist with uses in both humans and animals. Ingestions occurring within the United States are generally due to incidental ingestion of a veterinary product, use as a cutting agent for illicit substances, or illegal use for performance-enhancing purposes. CASE REPORT: A four-and-a-half year-old male presented approximately two-and-a-half hours after an accidental ingestion of an unknown quantity of clenbuterol...
January 22, 2019: Journal of Pharmacy Practice
https://read.qxmd.com/read/30640888/catecholaminergic-polymorphic-ventricular-tachycardia-the-cardiac-arrest-where-epinephrine-is-contraindicated
#6
David Bellamy, Gabrielle Nuthall, Stuart Dalziel, Jonathan R Skinner
OBJECTIVES: To raise awareness among pediatric intensive care specialists of catecholaminergic polymorphic ventricular tachycardia; an uncommon cause of polymorphic ventricular tachycardia and ventricular fibrillation arrest in children and young adults where epinephrine (adrenaline), even when given according to international protocols, can be counter-productive and life-threatening. We review three cases of cardiac arrest in children, later proven to be catecholaminergic polymorphic ventricular tachycardia related, where delay in recognition of this condition resulted in significantly longer resuscitation efforts, more interventions, and a longer time to return of spontaneous circulation...
January 11, 2019: Pediatric Critical Care Medicine
https://read.qxmd.com/read/30591737/immediate-and-short-term-effects-of-percutaneous-atrial-septal-defect-device-closure-on-cardiac-electrical-remodeling-in-children
#7
Alaa Mahmoud Roushdy, Hebatalla Attia, Heba Nossir
Background: The beneficial effects of atrial septal defect (ASD) device closure on electrical cardiac remodeling are well established. The timing at which these effects starts to take place has yet to be determined. Objectives: To determine the immediate and short term effects of ASD device closure on cardiac electric remodeling in children. Methods: 30 pediatric patients were subjected to 12 lead Electrocardiogram immediately before ASD device closure, 24 h post procedure, 1 and 6 months after...
December 2018: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://read.qxmd.com/read/30573213/can-pediatric-practitioners-correctly-interpret-electrocardiograms
#8
Sahil Khanna, V Ramesh Iyer, Victoria L Vetter
OBJECTIVES: To assess the impact of participation in an educational presentation on electrocardiogram (ECG) interpretation in children on pediatric practitioners' ability to accurately interpret ECGs. STUDY DESIGN: Pediatric healthcare providers at a pediatric clinic with >65 000 visits/year were eligible to participate. A 1-hour ECG educational module that provided a systematic approach to ECG interpretation was presented to 8 providers who consented (6 pediatricians, 2 pediatric nurse practitioners)...
December 17, 2018: Journal of Pediatrics
https://read.qxmd.com/read/30516532/can-flecainide-totally-eliminate-bidirectional-ventricular-tachycardia-in-pediatric-patients-with-andersen-tawil-syndrome
#9
Yakup Ergül, Senem Özgür, Sertaç Hanedan Onan, Volkan Tuzcu
Andersen-Tawil syndrome (ATS) is a disorder that causes episodes of muscle weakness (periodic paralysis), changes in heart rhythm, and developmental abnormalities. QT prolongation and ventricular arrhythmias, including bidirectional ventricular tachycardia (VT) and polymorphic VT, may occur. About 60% of all cases of the disorder arecaused by mutations in the KCNJ2 gene. A 13-year-old female patient was referred for frequent premature ventricular contractions. Suspicion of ATS due to dysmorphic findings, electrocardiogram changes, and periodic muscle weakness was genetically confirmed...
December 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://read.qxmd.com/read/30447383/attitudes-beliefs-and-practices-of-pediatric-palliative-care-physicians-regarding-the-use-of-methadone-in-children-with-advanced-cancer
#10
Kevin Madden, Diane Liu, Eduardo Bruera
CONTEXT: Methadone is a long-acting opioid known for its unique pharmacokinetic and pharmacodynamic properties. Most research on methadone in children is limited to its effect on the prolongation of the corrected QT (QTc) interval. OBJECTIVES: To better understand the attitudes, beliefs, and practices of pediatric palliative care physicians regarding the use of methadone in children with advanced cancer. METHODS: A survey was sent to The American Academy of Pediatrics Section of Hospice and Palliative Medicine LISTSERV®...
November 14, 2018: Journal of Pain and Symptom Management
https://read.qxmd.com/read/30371107/lack-of-utility-in-performing-blood-glucose-measurement-and-electrocardiogram-in-the-outpatient-evaluation-of-benign-pediatric-syncope
#11
Ayush Gupta, William Bonadio
We aimed to determine the frequency of blood glucose and electrocardiogram (EKG) abnormalities in previously healthy children who present to an emergency department (ED) with a diagnosis of benign syncope. Chart review of consecutive children aged 5 to 18 years presenting to the pediatric ED from 2004 to 2014 with a discharge diagnosis of benign syncope was done. Of 969 patients, hypoglycemia (serum glucose <60 mg/dL) was present in only 3 cases (0.3%). Of 754 patients with EKG performed, only 4 cases (0...
October 29, 2018: Clinical Pediatrics
https://read.qxmd.com/read/30351471/application-of-pediatric-appropriate-use-criteria-for-initial-outpatient-evaluation-of-asymptomatic-patients-with-abnormal-electrocardiograms
#12
Soham Dasgupta, Shae Anderson, Michael Kelleman, Ritu Sachdeva
INTRODUCTION: In the pediatric Appropriate Use Criteria (AUC), abnormal electrocardiogram (ECG) in an asymptomatic patient has been rated as an "Appropriate" indication for transthoracic echocardiogram (TTE). We hypothesized that the yield of abnormal findings on TTE for this indication will be low. METHODS: All asymptomatic patients (≤ 18 years) from January 1, 2015 to December 31, 2017 who underwent initial outpatient evaluation at our center and had a TTE ordered for an abnormal ECG, were included...
October 23, 2018: Congenital Heart Disease
https://read.qxmd.com/read/30335689/seizures-meds-and-vtach-a-journey-to-a-brugada-diagnosis
#13
David P Fitzgerald, Srikant Das, Matthew P Malone, B Shane Holland, Stephen M Schexnayder
Sudden cardiac arrest of cardiac etiology is rare in children and adolescents and most often occurs with exertion. Conversely, syncope is a common pediatric emergency department complaint but rarely is associated with a serious underlying cardiac disorder. This report describes a case of the channelopathy Brugada syndrome (BrS) as a cause of sudden cardiac arrest in a febrile preadolescent child taking medications known to affect cardiac conduction. The patient received cardiopulmonary resuscitation and was successfully defibrillated...
October 17, 2018: Pediatric Emergency Care
https://read.qxmd.com/read/30333292/echocardiography-guided-percutaneous-closure-of-patent-ductus-arteriosus-without-arterial-access-feasibility-and-safety-for-a-new-strategy
#14
Weizhi Zhang, Lei Gao, Wancun Jin, Qin Wu, Shijun Hu, Yifeng Yang, Tianli Zhao
To evaluate the feasibility and safety of device closure of patent ductus arteriosus (PDA) using only venous access under echocardiography guidance alone.
 Methods: A total of 102 consecutive pediatric patients underwent transcatheter PDA closure without arterial access, under the guidance of only echocardiography. The patients were followed up by clinical examination, electrocardiogram, and echocardiogram at 1, 3, 6 12, and 24 months.
 Results: Transvenous PDA closure under echocardiographic guidance was successful in 99 (97...
September 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/30271014/predictors-of-abnormal-electrocardiograms-in-the-pediatric-emergency-department
#15
Shiv Gandhi, Miranda Lin, Sharon R Smith, Jesse J Sturm
Background: Electrocardiograms (ECGs) are ordered in the pediatric emergency room for a wide variety of chief complaints. Objectives: Criteria are lacking as to when physicians should obtain ECGs. This study uses a large retrospective cohort of 880 pediatric emergency department (ED) patients to highlight objective criteria including significant medical history and specific vital sign abnormalities to guide clinicians as to which patients might have an abnormal ECG...
September 2018: Annals of Pediatric Cardiology
https://read.qxmd.com/read/30254039/brugada-syndrome-associated-with-adolescent-loperamide-abuse
#16
Bryan Stefek, L Timothy Wolfe, Mark Cohen
We present the case of a 14-year-old boy with obesity, hypertension, and chronic loperamide abuse who presented to our facility with symptoms of opioid withdrawal and type 1 Brugada pattern on an electrocardiogram. He was treated for anxiety and withdrawal. There were no documented dysrhythmias. His Brugada pattern resolved by hospital day 5 and remained resolved 12 days postadmission. Genetic testing revealed a heterozygous missense mutation in the SCN5A gene (c. 5038G>A, p. Ala1680Thr), which has been reported in association with Brugada syndrome...
October 2018: Pediatrics
https://read.qxmd.com/read/30214250/rupatadine-oral-solution-for-2-5-year-old-children-with-allergic-rhinitis-a-safety-open-label-prospective-study
#17
Eva Santamaría, Iñaki Izquierdo, Marta Valle, Jan Vermeulen, Paul Potter
Background: There are few clinical trials that assess the efficacy of antihistamines in very young children. Rupatadine is a second-generation antihistamine indicated for the treatment of allergic rhinitis (AR) and urticaria. In this study, AR symptoms were evaluated before and after daily 1 mg/mL rupatadine oral solution administration in 2-5-year-old children. Methods: A multicenter open-label study was carried out in 2-5-year-old children with AR. Safety assessments were collected during the study including spontaneous adverse events, vital signs, and electrocardiogram (QTc interval)...
2018: Journal of Asthma and Allergy
https://read.qxmd.com/read/30188452/evaluation-of-a-magnetic-tracking-and-electrocardiogram-based-tip-confirmation-system-for-peripherally-inserted-central-catheters-in-pediatric-patients
#18
Nina Rosche, Wolfgang Stehr
The purpose of this study was to investigate whether a magnetic tracking and electrocardiogram-based tip confirmation system (TCS) (Sherlock 3CG Tip Confirmation System; Bard, Covington, GA) permits safe and correct placement of a peripherally inserted central catheter (PICC) in the pediatric population. A total of 144 PICCs were placed using the TCS. After excluding participants for various reasons, 112/121 (92.56%) of PICCs were appropriately placed using the TCS. The TCS confirmed tip location an average of 7 to 18 minutes faster than radiographic imaging...
September 2018: Journal of Infusion Nursing: the Official Publication of the Infusion Nurses Society
https://read.qxmd.com/read/30152133/pediatric-noncompaction-patients-with-high-spatial-qrs-t-angles-are-at-increased-risk-for-ventricular-tachycardia
#19
Daniel Cortez, Nandita Sharma, Jason R Imundo
INTRODUCTION: Noncompaction cardiomyopathy (NCCM) patients may develop sustained ventricular arrhythmias (VA). Currently no known electrocardiogram (ECG) parameter has demonstrated predictive value for VA development. The spatial QRS-T angle has demonstrated ability to identify VA in other cardiomyopathy populations. METHODS: A total of 39 patients with NCCM, defined by compact to non-compact ratio of >2.3 by magnetic resonance imaging, were assessed. The first ECG taken at time of MRI was assessed utilizing the heart rate, the QRS duration (QRSd), the corrected QT interval (QTc), and the spatial QRS-T angle (SPQRS-T angle, three-dimensional angle between the QRS and T-wave vectors) were assessed...
August 27, 2018: Annals of Noninvasive Electrocardiology
https://read.qxmd.com/read/30080938/echocardiographic-diagnosis-of-atrial-flutter-in-a-neonate
#20
Samantha Low, Carmen Kiper, Aimee Armstrong, Clifford L Cua
A pregnant female presented at 37 weeks of gestation in labor. The fetus was noted to be tachycardic on fetal monitor. Postnatally, the male neonate was still noted to be tachycardic with heart rates in the low 200 bpm range. EKG was consistent with tachycardia, but rhythm diagnosis was not definitively made. Echocardiogram with M-mode analysis clearly demonstrated 2:1 atrial to ventricular contraction pattern consistent with atrial flutter. The neonate was subsequently transferred to a tertiary pediatric hospital where the diagnosis of atrial flutter was confirmed...
September 2018: Echocardiography
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