keyword
https://read.qxmd.com/read/38558960/potocki-lupski-syndrome-in-ethiopian-child-a-case-report
#1
Endayen Deginet, Deme Abdissa, Tadele Hailu
BACKGROUND: Potocki-Lupski syndrome (PTLS) is a rare developmental disorder resulting from the partial duplication of the short arm of chromosome 17. Affected children may have hypotonia, facial dysmorphism, or neurological abnormalities. CASE PRESENTATION: We present the case of a 5-year-old female patient from Ethiopia diagnosed with Potocki-Lupski syndrome (PTLS)(17p11.2 microduplication) through multiplex ligation-dependent probe amplification (MLPA) testing...
2024: Pediatric Health, Medicine and Therapeutics
https://read.qxmd.com/read/38445110/a-qualitative-exploration-of-ambulance-clinician-behaviour-and-decision-making-to-identify-factors-influencing-on-scene-times-for-suspected-stroke-patients-in-north-east-england
#2
JOURNAL ARTICLE
Abi Alton, Lisa Shaw, Tracy Finch, Christopher Price, Graham McClelland
AIMS/OBJECTIVES: Ambulance clinician assessment of suspected stroke patients aims to provide rapid access to specialist care, however regional and national data show increasing pre-hospital times. This study explored paramedic views about factors contributing to on-scene time (OST) for suspected stroke patients, with a view to identifying opportunities for future interventions, to reduce OST. METHODS: Views of paramedics from one regional service on factors influencing OST were explored using a qualitative approach...
March 1, 2024: British paramedic journal
https://read.qxmd.com/read/38384147/a-stroke-prediction-framework-using-explainable-ensemble-learning
#3
JOURNAL ARTICLE
Mostarina Mitu, S M Mahedy Hasan, Md Palash Uddin, Md Al Mamun, Venkatesan Rajinikanth, Seifedine Kadry
The death of brain cells occurs when blood flow to a particular area of the brain is abruptly cut off, resulting in a stroke. Early recognition of stroke symptoms is essential to prevent strokes and promote a healthy lifestyle. FAST tests (looking for abnormalities in the face, arms, and speech) have limitations in reliability and accuracy for diagnosing strokes. This research employs machine learning (ML) techniques to develop and assess multiple ML models to establish a robust stroke risk prediction framework...
February 21, 2024: Computer Methods in Biomechanics and Biomedical Engineering
https://read.qxmd.com/read/38326263/knowledge-and-attitude-towards-stroke-among-the-population-of-one-rural-community-in-southern-thailand-a-survey
#4
JOURNAL ARTICLE
Worawit Wanichanon, Thareerat Ananchaisarp, Napakkawat Buathong, Kittisakdi Choomalee
OBJECTIVE: To evaluate attitude and knowledge of stroke in a rural community in southern Thailand. DESIGN: A survey. SETTING: A community in southern Thailand. PARTICIPANTS: All community members aged ≥18 years who were at home during the survey were invited to participate. PRIMARY AND SECONDARY OUTCOME MEASURES: Level of attitude and knowledge score towards stroke were assessed, and the associated factors were evaluated...
February 7, 2024: BMJ Open
https://read.qxmd.com/read/38074343/telerehabilitation-for-lee-silverman-voice-treatment-tele-lsvt-loud-on-voice-intensity-and-voice-use-in-daily-living-in-people-with-multiple-sclerosis-a-protocol-for-a-feasibility-and-pilot-randomized-controlled-study
#5
JOURNAL ARTICLE
Chiara Vitali, Giulia Fusari, Cinzia Baldanzi, Diego Michael Cacciatore, Valeria Crispiatico, Alessio Carullo, Marco Rovaris, Davide Cattaneo, Francesca Baglio, Sara Isernia
OBJECTIVE: Alterations in voice intensity and quality may constitute a social life limitation in people with multiple sclerosis (MS), but only 2% of cases receive speech therapy. Especially the Lee Silverman Voice Treatment (LSVT)-Loud is a highly effective intensive method for voice intensity, requiring subjects' repeated attendance at the clinic. Telerehabilitation may represent a feasible solution to bypass potential barriers related to speech therapy attendance, scaling up the beneficial effects of the treatment to a broader population...
2023: Digital Health
https://read.qxmd.com/read/38011356/a-nomogram-based-clinical-tool-for-acute-ischemic-stroke-screening-in-prehospital-setting
#6
JOURNAL ARTICLE
Alireza Baratloo, Mahtab Ramezani, Hosein Rafiemanesh, Meisam Sharifi, Somayeh Karimi
Background: We believe that designing a new tool which is comparable in terms of both sensitivity and specificity may play an important role in rapid and more accurate diagnosis of acute ischemic stroke (AIS) in prehospital stage. Therefore, we intended to develop a new clinical tool for the diagnosis of AIS in the prehospital stage. Methods: This was a cross-sectional diagnostic accuracy study. All patients transferred to the emergency department (ED) who underwent brain magnetic resonance imaging (MRI) with impression of AIS were evaluated by 9 clinical tools for stroke diagnosis in the pre-hospital phase including Rapid Arterial Occlusion Evaluation (RACE), Cincinnati Prehospital Stroke Scale (CPSS), Los Angeles Prehospital Stroke Screen (LAPSS), Melbourne Ambulance Stroke Screen (MASS), Medic Prehospital Assessment for Code Stroke (Med PACS), Ontario Prehospital Stroke Screening Tool (OPSS), PreHospital Ambulance Stroke Test (PreHAST), Recognition of Stroke in the Emergency Room (ROSIER), and Face Arm Speech Test (FAST), and totally 19 items were reviewed and recorded...
January 5, 2023: Current journal of neurology
https://read.qxmd.com/read/37968092/prehospital-identification-of-acute-ischaemic-stroke-with-large-vessel-occlusion-a-retrospective-study-from-western-norway
#7
JOURNAL ARTICLE
Nedim Leto, Conrad Arnfinn Bjørshol, Martin Kurz, Øyvind Østerås, Annette Fromm, Thomas Werner Lindner
BACKGROUND: In 2019, the emergency medical services (EMS) covering the western Norway Regional Health Authority area implemented its version of the prehospital clinical criteria G-FAST (Gaze deviation, Facial palsy, Arm weakness, Visual loss, Speech disturbance) to detect acute ischaemic stroke (AIS) with large vessel occlusion (LVO). For patients with gaze deviation and at least one other G-FAST symptom, a primary stroke centre (PSC) may be bypassed and the patient taken directly to a comprehensive stroke centre (CSC) for rapid endovascular treatment (EVT) evaluation...
November 15, 2023: Emergency Medicine Journal: EMJ
https://read.qxmd.com/read/37819707/effect-of-voice-and-articulation-parameters-of-a-home-based-serious-game-for-speech-therapy-in-children-with-articulation-disorder-prospective-single-arm-clinical-trial
#8
JOURNAL ARTICLE
Seong-Yeol Kim, Minji Song, Yunju Jo, Youngjae Jung, Heecheon You, Myoung-Hwan Ko, Gi-Wook Kim
BACKGROUND: Articulation disorder decreases the clarity of language and causes a decrease in children's learning and social ability. The demand for non-face-to-face treatment is increasing owing to the limited number of therapists and geographical or economic constraints. Non-face-to-face speech therapy programs using serious games have been proposed as an alternative. OBJECTIVE: The aim of this study is to investigate the efficacy of home therapy on logopedic and phoniatric abilities in children with articulation disorder using the Smart Speech game interface...
October 11, 2023: JMIR Serious Games
https://read.qxmd.com/read/37674916/paramedic-recognition-of-posterior-circulation-stroke-a-vignette-and-focus-group-study
#9
JOURNAL ARTICLE
Shane Devlin, Gerard Bury
INTRODUCTION: The main pre-hospital screening tool used for stroke in Ireland and the United Kingdom is the FAST (face, arms, speech, time) test. However, posterior circulation stroke (PCS) patients may be FAST negative on exam, presenting with sudden dizziness, headaches, visual problems, nausea and vomiting and balance/co-ordination problems. There is a lack of research into paramedic recognition of PCS, and this study sought to evaluate recognition rates among paramedics (Ps) and advanced paramedics (APs) in Ireland...
September 1, 2023: British paramedic journal
https://read.qxmd.com/read/37120338/effect-of-using-g-fast-to-recognize-emergent-large-vessel-occlusion-a-city-wide-community-experience
#10
JOURNAL ARTICLE
Kai-Wei Lin, Ying-Ju Chen, Sheng-Wen Hou, Sung-Chun Tang, Wen-Chu Chiang, Li-Kai Tsai, Chung-Wei Lee, Yu-Ching Lee, Yu-Chun Chien, Ming-Ju Hsieh, Jiann-Shing Jeng, Matthew Huei-Ming Ma
BACKGROUND/PURPOSE: A prehospital bypass strategy was suggested for large vessel occlusion. This study aimed to evaluate the effect of a bypass strategy using the gaze-face-arm-speech-time test (G-FAST) implemented in a metropolitan community. METHODS: Pre-notified patients with positive Cincinnati Prehospital Stroke Scale and symptom onset <3 h from July 2016 to December 2017 (pre-intervention period) and those with positive G-FAST and symptom onset <6 h from July 2019 to December 2020 (intervention period) were included...
October 2023: Journal of the Formosan Medical Association
https://read.qxmd.com/read/37010730/impact-of-bilingual-face-arm-speech-time-fast-public-awareness-campaigns-on-emergency-medical-services-ems-activation-in-a-large-canadian-metropolitan-area
#11
JOURNAL ARTICLE
Vincent Brissette, Bastien Rioux, Thérésa Choisi, Alexandre Y Poppe
BACKGROUND AND AIMS: Face, arm, speech, time (FAST) public awareness campaigns improve stroke recognition in the general population. Whether this translates into improved emergency medical services (EMS) activation remains unclear. We assessed the association of five consecutive FAST campaigns with EMS calls for suspected strokes in a large urban area of Quebec, Canada. METHODS: We conducted an observational study to assess data collected between June 2015 and December 2019 by the public EMS agency covering the cities of Laval and Montreal (Quebec, Canada)...
April 3, 2023: CJEM
https://read.qxmd.com/read/36452022/not-so-fast-pre-hospital-posterior-circulation-stroke
#12
Shane Devlin
INTRODUCTION: Posterior circulation strokes account for 20% of ischaemic strokes, but may present differently to their anterior circulation counterparts. Patients may not exhibit unilateral facial weakness, speech disturbances and unilateral limb weakness, but instead present with more vague symptoms of sudden headache, dizziness, loss of balance and visual problems. This case describes a patient displaying signs and symptoms of a posterior stroke, but who eluded the FAST (face, arm, speech, time) test...
June 1, 2022: British paramedic journal
https://read.qxmd.com/read/36446232/myoclonus-status-revealing-covid-19-infection
#13
JOURNAL ARTICLE
Dina Ben Mohamed, Rania Zouari, Jihen Ketata, Fatma Nabli, Samir Blel, Samia Ben Sassi
INTRODUCTION: At the beginning of the coronavirus virus (COVID-19) pandemic, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) was thought to cause mainly respiratory symptoms, largely sparing the brain and the rest of the nervous system. However, as the knowledge about COVID-19 infection progresses and the number of COVID19-related neurological manifestations reports increases, neurotropism and neuroinvasion were finally recognized as major features of the SARS-CoV-2. Neurological manifestations involving the central nervous system are sparse, ranging from headaches, drowsiness, and neurovascular attacks to seizures and encephalitis [1]...
January 2023: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/36363498/stroke-scales-as-assessment-tools-in-emergency-settings-a-narrative-review
#14
REVIEW
Hrvoje Budinčević, Andrija Meštrović, Vida Demarin
In the last 20 years, substantial improvements have been made in stroke recanalization treatment. Good outcomes after modern reperfusion treatment require the rapid and accurate identification of stroke patients. Several stroke rating scales are available or have been proposed for the early recognition of stroke and the evaluation of stroke severity and outcome. This review aims to provide an overview of commonly used stroke scales in emergency and clinical settings. The most commonly used scale in a prehospital setting for stroke recognition is the Face, Arms, Speech, Time (FAST) test...
October 27, 2022: Medicina
https://read.qxmd.com/read/36269618/audiovisual-mandarin-lexical-tone-perception-in-quiet-and-noisy-contexts-the-influence-of-visual-cues-and-speech-rate
#15
JOURNAL ARTICLE
Manhong Li, Xiaoxiang Chen, Jiaqiang Zhu, Fei Chen
PURPOSE: Armed with the theory of embodied cognition proposing tight interactions between perception, motor, and cognition, this study aimed to test the hypothesis that speech rate-altered Mandarin lexical tone perception in quiet and noisy environments could be affected by the bodily dynamic cross-modal information. METHOD: Fifty-three adult listeners completed a Mandarin tone perception task with 720 tone stimuli in auditory-only (AO), auditory-facial (AF), and auditory-facial-plus-gestural (AFG) modalities, at fast, normal, and slow speech rates under quiet and noisy conditions...
October 21, 2022: Journal of Speech, Language, and Hearing Research: JSLHR
https://read.qxmd.com/read/36201961/an-updated-review-and-meta-analysis-of-screening-tools-for-stroke-in-the-emergency-room-and-prehospital-setting
#16
REVIEW
Durgesh Chaudhary, Johan Diaz, Yezhong Lu, Jiang Li, Vida Abedi, Ramin Zand
BACKGROUND: Stroke screening tools should have good diagnostic performance for early diagnosis and a proper therapeutic plan. This paper describes and compares various diagnostic tools used to identify stroke in emergency departments and prehospital setting. METHODS: The meta-analysis was conducted according to the Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies (PRISMA-DTA) guidelines. The PubMed and Scopus databases were searched until December 31, 2021, for studies published on stroke screening tools...
November 15, 2022: Journal of the Neurological Sciences
https://read.qxmd.com/read/36058230/prehospital-transdermal-glyceryl-trinitrate-in-patients-with-presumed-acute-stroke-mr-asap-an-ambulance-based-multicentre-randomised-open-label-blinded-endpoint-phase-3-trial
#17
RANDOMIZED CONTROLLED TRIAL
Sophie A van den Berg, Simone M Uniken Venema, Hendrik Reinink, Jeannette Hofmeijer, Wouter J Schonewille, Irene Miedema, Puck S S Fransen, D Martijn O Pruissen, Theodora W M Raaijmakers, Gert W van Dijk, Frank-Erik de Leeuw, Jorine A van Vliet, Vincent I H Kwa, Henk Kerkhoff, Alex van 't Net, Rene Boomars, Arjen Siegers, Tycho Lok, Klaartje Caminada, Laura M Esteve Cuevas, Marieke C Visser, Casper P Zwetsloot, Jooske M F Boomsma, Mirjam H Schipper, Roeland P J van Eijkelenburg, Olvert A Berkhemer, Daan Nieboer, Hester F Lingsma, Bart J Emmer, Robert J van Oostenbrugge, Aad van der Lugt, Yvo B W E M Roos, Charles B L M Majoie, Diederik W J Dippel, Paul J Nederkoorn, H Bart van der Worp
BACKGROUND: Pooled analyses of previous randomised studies have suggested that very early treatment with glyceryl trinitrate (also known as nitroglycerin) improves functional outcome in patients with acute ischaemic stroke or intracerebral haemorrhage, but this finding was not confirmed in a more recent trial (RIGHT-2). We aimed to assess whether patients with presumed acute stroke benefit from glyceryl tr initrate started within 3 h after symptom onset. METHODS: MR ASAP was a phase 3, randomised, open-label, blinded endpoint trial done at six ambulance services serving 18 hospitals in the Netherlands...
November 2022: Lancet Neurology
https://read.qxmd.com/read/34930750/parkinsong-online-protocol-for-a-telehealth-feasibility-study-of-therapeutic-group-singing-for-people-with-parkinson-s-disease
#18
JOURNAL ARTICLE
Jeanette Tamplin, Meg E Morris, Felicity A Baker, Tanara Vieira Sousa, Simon Haines, Stephen Dunn, Victoria Tull, Adam P Vogel
INTRODUCTION: Parkinson's disease can be associated with speech deterioration and low communication confidence which in turn compromises social interaction. Therapeutic singing is an engaging method for combatting speech decline; however, face-to-face delivery can limit access to group singing. The aim of this study is to test the feasibility and acceptability of an online mode of delivery for a Parkinson's singing intervention (ParkinSong) as well as remote data collection procedures...
December 20, 2021: BMJ Open
https://read.qxmd.com/read/34820340/case-report-potocki-lupski-syndrome-in-five-siblings
#19
Alina Grama, Claudia Sîrbe, Diana Miclea, Simona Sorana Cǎinap, Delia Huniadi, Bogdan Bulata, Tudor Lucian Pop
Potocki-Lupski syndrome (PTLS) is a rare developmental disorder resulting from the partial duplication of the short arm of chromosome 17. Affected children may have hypotonia, facial dysmorphism, or neurological abnormalities. PTLS is also frequently associated with failure to thrive due to swallowing difficulties or growth hormone deficiency. We report the first Romanian family (a mother and her five children) diagnosed with PTLS (17p11.2 microduplication). Fortunately, they present a less severe form of the disease...
2021: Frontiers in Pediatrics
https://read.qxmd.com/read/34488307/a-multicenter-diagnostic-accuracy-study-on-prehospital-stroke-screening-scales
#20
MULTICENTER STUDY
Peyman Saberian, Hosein Rafiemanesh, Farhad Heydari, Sahar Mirbaha, Somayeh Karimi, Alireza Baratloo
BACKGROUND: Stroke is one of the most common debilitating diseases. Although effective treatment is available, a golden time has been defined in this regard. Therefore, prompt action is needed to identify patients with stroke as soon as possible, even in the pre-hospital stage. In recent years, several clinical scales have been introduced for this purpose. We performed the present study to examine the accuracy of eight clinical scales in terms of stroke diagnosis. METHODS: This multicenter diagnostic accuracy study was conducted in 2019...
June 1, 2021: Archives of Iranian Medicine
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