André Lopes Simão, Carolina Santos Palma, Laura Izquierdo-Sanchez, Antonella Putignano, Angela Carvalho-Gomes, Andreas Posch, Paola Zanaga, Irina Girleanu, Mariana Moura Henrique, Carlos Araújo, Delphine Degre, Thierry Gustot, Iván Sahuco, Elia Spagnolo, Sofia Carvalhana, Miguel Moura, Diogo Ae Fernandes, Jesus M Banales, Manuel Romero-Gomez, Anca Trifan, Francesco Paolo Russo, Rudolf Stauber, Marina Berenguer, Christophe Moreno, João Gonçalves, Helena Cortez-Pinto, Rui E Castro
BACKGROUND & AIMS: The response of patients with chronic liver disease (CLD) to COVID-19 vaccines remains unclear. Our aim was to assess the humoral immune response and efficacy of two-dose COVID-19 vaccines among CLD patients of different etiologies and disease stages. METHODS: 357 patients were recruited in clinical centers from 6 European countries. 132 healthy volunteers served as controls. Serum IgG, IgM (nM) and neutralizing antibodies (NAb; %) against the Wuhan-Hu-1, B...
February 20, 2023: JHEP reports: innovation in hepatology