Jeanne Leseur, Charlotte Boiret, Alix Romier, Balthazar Bazin, Louise Basquin, Emilie Stern, Guillaume Pineau, Michel Lejoyeux, Pierre A Geoffroy, Julia Maruani
Currently, there is a major challenge in distinguishing between unipolar and bipolar major depressive episode. A significant body of research has been dedicated to identifying biomarkers that can aid in this differentiation due to its crucial implications, particularly for therapeutic and prognostic purposes. Among the biomarkers of interest, markers related to sleep and circadian rhythms show promise and could potentially aid in making this distinction. Nevertheless, no study has simultaneously examined sleep-wake disorders, circadian rhythms, and seasonal patterns using both subjective and objective measures...
February 20, 2024: Psychiatry Research