keyword
https://read.qxmd.com/read/38530635/circadian-photoentrainment-varies-by-season-and-depressed-state-associations-between-light-sensitivity-and-sleep-and-circadian-timing
#1
JOURNAL ARTICLE
Delainey L Wescott, Brant P Hasler, Peter L Franzen, Maddison L Taylor, Alison M Klevens, Paul Gamlin, Greg J Siegle, Kathryn A Roecklein
STUDY OBJECTIVES: Altered light sensitivity may be an underlying vulnerability for disrupted circadian photoentrainment. The photic information necessary for circadian photoentrainment is sent to the circadian clock from melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). The current study tested whether the responsivity of ipRGCs measured using the post-illumination pupil response (PIPR) was associated with circadian phase, sleep timing, and circadian alignment, and if these relationships varied by season or depression severity...
March 6, 2024: Sleep
https://read.qxmd.com/read/38524170/the-effect-of-chronotypes-on-follow-up-outcomes-of-patients-with-substance-use-disorder
#2
JOURNAL ARTICLE
Ozlem Akcay Ciner, Ali Savas Cilli, Ahmet Bulent Yazici, Hasan Bakay, Şakir Gica
Substance use disorder (SUD) can have circadian characteristics and individuals with evening chronotype are more prone to addiction. In this study, the effect of chronotypes on the treatment outcomes of SUD was investigated. The study included 66 patients who were diagnosed with SUD according to DSM-5. Two clinical interviews were conducted at 6-month intervals, and remission/relapse status was evaluated at the second interview. The Structured Clinical Interview Form for DSM-IV Axis I Disorders (SCID-I), Addiction Profile Index Practitioner Form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Pittsburg Sleep Quality Index and Morningness-Eveningness Questionnaire (MEQ) were applied to the patients...
April 2024: Sleep and Biological Rhythms
https://read.qxmd.com/read/38519958/sleep-alterations-as-a-function-of-88-health-indicators
#3
JOURNAL ARTICLE
Péter Przemyslaw Ujma, Róbert Bódizs
BACKGROUND: Alterations in sleep have been described in multiple health conditions and as a function of several medication effects. However, evidence generally stems from small univariate studies. Here, we apply a large-sample, data-driven approach to investigate patterns between in sleep macrostructure, quantitative sleep EEG, and health. METHODS: We use data from the MrOS Sleep Study, containing polysomnography and health data from a large sample (N = 3086) of elderly American men to establish associations between sleep macrostructure, the spectral composition of the electroencephalogram, 38 medical disorders, 2 health behaviors, and the use of 48 medications...
March 22, 2024: BMC Medicine
https://read.qxmd.com/read/38509807/shift-work-sleep-disorder-and-mental-health-an-integrative-review-of-neurobiological-sociological-and-psychological-perspectives-with-public-policy-implications
#4
JOURNAL ARTICLE
Anne M Fink
Shift workers support critical 24-hr operations; their health can be impaired by disrupted circadian rhythms and dysfunctional sleep. Shift work sleep disorder (SWSD) is a prevalent condition with significant psychological consequences. Nurse leaders have not yet implemented effective policies to prevent SWSD and optimize shift workers' mental health. The purpose of this integrative review was to examine research about SWSD within the context of neurobiological, sociological, and psychological perspectives that can inform policy changes...
March 21, 2024: Policy, Politics & Nursing Practice
https://read.qxmd.com/read/38504557/long-term-effects-of-environmental-dynamic-lighting-on-sleep-wake-rhythm-mood-and-behaviour-in-older-adults-with-intellectual-disabilities
#5
JOURNAL ARTICLE
M N Böhmer, A Oppewal, P J E Bindels, E J W van Someren, D A M Festen
BACKGROUND: Sleep-wake problems and depressive symptoms are common in people with intellectual disabilities (IDs) and are thought to be related to the unstable sleep-wake rhythm in this population. Previously, we showed that after increasing environmental light exposure, mid-sleep and sleep onset advanced, and mood improved over a period of 14 weeks after installing environmental dynamic light installations in the living room of people with IDs. We invited participants of that short-term study to take part in the current study on sleep-wake rhythm, mood and behaviour in older adults with IDs 1 year after installing environmental dynamic light installations in the common living rooms of six group homes...
March 19, 2024: Journal of Intellectual Disability Research: JIDR
https://read.qxmd.com/read/38499183/daytime-aspartame-intake-results-in-larger-influences-on-body-weight-serum-corticosterone-level-serum-cerebral-cytokines-levels-and-depressive-like-behaviors-in-mice-than-nighttime-intake
#6
JOURNAL ARTICLE
Haiyuan Ma, Jiapeng Deng, Jing Liu, Xiaobao Jin, Junhua Yang
Aspartame (APM) is one of the most widely used artificial sweeteners worldwide. Studies have revealed that consuming APM may negatively affect the body, causing oxidative stress damage to multiple organs and leading to various neurophysiological symptoms. However, it's still unclear if consuming APM and one's daily biological rhythm have an interactive effect on health. In this study, healthy adult C57BL/6 mice were randomly divided into four groups: Control group (CON), oral gavage sham group (OGS), daytime APM intragastric group (DAI) and nighttime APM intragastric group (NAI)...
March 16, 2024: Neurotoxicology
https://read.qxmd.com/read/38496579/fibroblasts-as-an-in-vitro-model-of-circadian-genetic-and-genomic-studies-a-temporal-analysis
#7
Marcelo Francia, Merel Bot, Toni Boltz, Juan F De la Hoz, Marco Boks, René Kahn, Roel Ophoff
Bipolar disorder (BD) is a heritable disorder characterized by shifts in mood that manifest in manic or depressive episodes. Clinical studies have identified abnormalities of the circadian system in BD patients as a hallmark of underlying pathophysiology. Fibroblasts are a well-established in vitro model for measuring circadian patterns. We set out to examine the underlying genetic architecture of circadian rhythm in fibroblasts, with the goal to assess its contribution to the polygenic nature of BD disease risk...
March 5, 2024: bioRxiv
https://read.qxmd.com/read/38474214/new-light-on-prions-putative-role-of-prp-c-in-pathophysiology-of-mood-disorders
#8
REVIEW
Adrian Andrzej Chrobak, Patrycja Pańczyszyn-Trzewik, Patrycja Król, Magdalena Pawelec-Bąk, Dominika Dudek, Marcin Siwek
Mood disorders are highly prevalent and heterogenous mental illnesses with devastating rates of mortality and treatment resistance. The molecular basis of those conditions involves complex interplay between genetic and environmental factors. Currently, there are no objective procedures for diagnosis, prognosis and personalization of patients' treatment. There is an urgent need to search for novel molecular targets for biomarkers in mood disorders. Cellular prion protein (PrPc ) is infamous for its potential to convert its insoluble form, leading to neurodegeneration in Creutzfeldt-Jacob disease...
March 4, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38472403/-overview-of-chronobiological-and-sleep-medical-aspects-of-depression-in-adolescents
#9
REVIEW
Neda Ghotbi, Aline Doreen Scherff, Ellen Greimel, Gerd Schulte-Körne
Changes in sleep are reported in adolescents with depression with a frequency of up to 71%. Aspects of chronobiology and sleep based on the current scientific literature are illustrated and summarized in this narrative review. The circadian clock synchronizes organisms to the light-dark structure of the environment. The individual synchronization is called "chronotype." Chronotype changes according to age, among other factors, and adolescents experience the latest chronotypes overall. The potential discrepancy between internal and external time is called "social jetlag...
March 12, 2024: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://read.qxmd.com/read/38469283/sleep-disturbance-in-adults-with-untreated-primary-brain-tumors-prevalence-and-impact-on-quality-of-life
#10
JOURNAL ARTICLE
Pei-Ching Lin, Pin-Yuan Chen, Kuo-Chen Wei, Jian-Her Lin, Mei-Ru Lin, Huan-Chih Wang, Hsiao-Yean Chiu
PURPOSE: To investigate the frequency of sleep disturbance and its effects on quality of life in adults with untreated primary brain tumors. METHODS: This cross-sectional study recruited 68 and 35 patients with newly diagnosed benign and malignant brain tumors, respectively. All participants completed the Chinese versions of the Athens Insomnia Scale, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Hospital Anxiety and Depression Scale, Brief Fatigue Inventory, and EORTC-QLQ-BN20 for quality-of-life assessment...
April 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38469083/the-eveningness-chronotype-is-associated-with-nightmare-distress-and-dream-recall-a-cross-sectional-study
#11
JOURNAL ARTICLE
Yi-Seul Choo, Sang Wook Hong, Ga Eun Koo, Su-Hyun Han
Dreaming may be affected by sleep behavior; however, evidence of the effect of chronotypes on dreaming is limited. We investigated sleep patterns, dream recall, and nightmare distress according to chronotypes. This cross-sectional study retrospectively enrolled adult participants (age > 18 years) who visited a sleep laboratory between 2016 and 2021 and underwent standard polysomnography (PSG) and completed a self-reported questionnaire. Patients with major sleep disorders were excluded...
July 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38442480/comparative-study-of-sleep-and-circadian-rhythms-in-patients-presenting-unipolar-or-bipolar-major-depressive-episodes
#12
JOURNAL ARTICLE
Jeanne Leseur, Charlotte Boiret, Alix Romier, Balthazar Bazin, Louise Basquin, Emilie Stern, Guillaume Pineau, Michel Lejoyeux, Pierre A Geoffroy, Julia Maruani
Currently, there is a major challenge in distinguishing between unipolar and bipolar major depressive episode. A significant body of research has been dedicated to identifying biomarkers that can aid in this differentiation due to its crucial implications, particularly for therapeutic and prognostic purposes. Among the biomarkers of interest, markers related to sleep and circadian rhythms show promise and could potentially aid in making this distinction. Nevertheless, no study has simultaneously examined sleep-wake disorders, circadian rhythms, and seasonal patterns using both subjective and objective measures...
February 20, 2024: Psychiatry Research
https://read.qxmd.com/read/38440104/patient-reported-outcomes-on-sleep-quality-and-circadian-rhythm-during-treatment-with-intravenous-ketamine-for-treatment-resistant-depression
#13
JOURNAL ARTICLE
Raymond Yan, Tyler Marshall, Atul Khullar, Travis Nagle, Jake Knowles, Mai Malkin, Brittany Chubbs, Jennifer Swainson
BACKGROUND: Intravenous (IV) ketamine is a rapid acting antidepressant used primarily for treatment-resistant depression (TRD). It has been suggested that IV ketamine's rapid antidepressant effects may be partially mediated via improved sleep and changes to the circadian rhythm. OBJECTIVES: This study explores IV ketamine's association with changes in patient-reported sleep quality and circadian rhythm in an adult population with TRD. METHODS: Adult patients (18-64 years) with TRD scheduled for IV ketamine treatment were recruited to complete patient rated outcomes measures on sleep quality using the Pittsburgh Sleep Quality Index (PSQI) and circadian rhythm using the Morningness-Eveningness Questionnaire (MEQ)...
2024: Therapeutic Advances in Psychopharmacology
https://read.qxmd.com/read/38432881/bidirectional-mechanism-of-comorbidity-of-depression-and-insomnia-based-on-synaptic-plasticity
#14
JOURNAL ARTICLE
Fanhao Meng, Long Wang
Insomnia is one of the most common accompanying symptoms of depression, with both sharing highly overlapping molecular pathways. The same pathological changes can trigger comorbidity of insomnia and depression, which further forms a vicious cycle with the involvement of more mechanisms and disease progression. Thus, understanding the potential interaction mechanisms between insomnia and depression is critical for clinical diagnosis and treatment. Comorbidity genetic factors, the hypothalamic-pituitary-adrenal axis, along with circadian rhythms of cortisol and the brain reward mechanism, are important ways in contributing to the comorbidity occurrence and development...
October 28, 2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/38425306/using-polygenic-scores-for-circadian-rhythms-to-predict-wellbeing-depressive-symptoms-chronotype-and-health
#15
JOURNAL ARTICLE
Anne Landvreugd, René Pool, Michel G Nivard, Meike Bartels
The association between circadian rhythms and diseases has been well established, while the association with mental health is less explored. Given the heritable nature of circadian rhythms, this study aimed to investigate the relationship between genes underlying circadian rhythms and mental health outcomes, as well as a possible gene-environment correlation for circadian rhythms. Polygenic scores (PGSs) represent the genetic predisposition to develop a certain trait or disease. In a sample from the Netherlands Twin Register ( N  = 14,021), PGSs were calculated for two circadian rhythm measures: morningness and relative amplitude (RA)...
March 1, 2024: Journal of Biological Rhythms
https://read.qxmd.com/read/38423243/chitosan-revokes-controlled-cortical-impact-generated-neurological-aberrations-in-circadian-disrupted-mice-via-tlr4-nlrp3-axis
#16
JOURNAL ARTICLE
Mohd Rabi Bazaz, Amit Asthana, Manoj P Dandekar
The severity of inevitable neurological deficits and long-term psychiatric disorders in the aftermath of traumatic brain injury is influenced by pre-injury biological factors. Herein, we investigated the therapeutic effect of chitosan lactate on neurological and psychiatric aberrations inflicted by circadian disruption (CD) and controlled-cortical impact (CCI) injury in mice. Firstly, CD was developed in mice by altering sporadic day-night cycles for 2 weeks. Then, CCI surgery was performed using a stereotaxic ImpactOne device...
February 27, 2024: European Journal of Pharmacology
https://read.qxmd.com/read/38413912/circadian-rhythms-of-melatonin-and-its-relationship-with-anhedonia-in-patients-with-mood-disorders-a-cross-sectional-study
#17
JOURNAL ARTICLE
Xinyu Li, Jiakuai Yu, Shuo Jiang, Liang Fang, Yifei Li, Shuangshuang Ma, Hui Kong, Ximing Qin, Daomin Zhu
BACKGROUND: Mood disorders are strongly associated with melatonin disturbances. However, it is unclear whether there is a difference in melatonin concentrations and melatonin circadian rhythm profiles between depression and bipolar disorder. In addition, the relationship between anhedonia, a common symptom of affective disorders, and its melatonin circadian rhythm remains under-investigated. METHODS: Thirty-four patients with depression disorder, 20 patients diagnosed with bipolar disorder and 21 healthy controls participated in this study...
February 27, 2024: BMC Psychiatry
https://read.qxmd.com/read/38413861/association-between-physical-frailty-circadian-syndrome-and-cardiovascular-disease-among-middle-aged-and-older-adults-a-longitudinal-study
#18
JOURNAL ARTICLE
Xinhong Zhu, Linlin Ding, Xiaona Zhang, Heqing Wang, Ningbo Chen
BACKGROUND: Physical frailty (PF) and circadian syndrome (CircS) are proposed as novel risks for cardiovascular disease (CVD), but little attention is paid to their combined impact on CVD. This study aimed to investigate the association of PF, CircS and CVD in middle-aged and older adults. METHODS: The sample comprised 8512 participants aged at least 45 years from the China Health and Retirement Longitudinal Study (CHARLS) 2011. PF was examined by the physical frailty phenotype scale...
February 27, 2024: BMC Geriatrics
https://read.qxmd.com/read/38403262/lights-at-night-mediate-depression-like-behavioral-and-molecular-phenotypes-in-a-glucocorticoid-dependent-manner-in-male-rats
#19
JOURNAL ARTICLE
Zhenlong Li, Chau-Shoun Lee, Hsien-Yu Peng, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Dylan Chou
Nocturnal light pollution, an underappreciated mood manipulator, disturbs the circadian rhythms of individuals in modern society. Preclinical and clinical studies have suggested that exposure to lights at night (LANs) results in depression-like phenotypes. However, the mechanism underlying the action of LANs remains unclear. Therefore, this study explored the potential influence of LANs on depression-related brain regions by testing brain-derived neurotrophic factor (BDNF), synaptic transmission, and plasticity in male Sprague-Dawley rats...
February 23, 2024: Neuropharmacology
https://read.qxmd.com/read/38398277/genetic-and-epigenetic-factors-associated-with-postpartum-psychosis-a-5-year-systematic-review
#20
REVIEW
Sophia Tsokkou, Dimitrios Kavvadas, Maria-Nefeli Georgaki, Kyriaki Papadopoulou, Theodora Papamitsou, Sofia Karachrysafi
Purpose: Postpartum psychosis (PPP) is a serious mental health illness affecting women post-parturition. Around 1 in 1000 women are affected by postpartum psychosis, and the symptoms usually appear within 2 weeks after birth. Postpartum mental disorders are classified into 3 main categories starting from the least to most severe types, including baby blues, postpartum depression, and postpartum psychosis. Materials and Methods: In this systematic review, genetic and epigenetic factors associated with postpartum psychosis are discussed...
February 8, 2024: Journal of Clinical Medicine
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