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Geriatric review

Ki Hyang Kim, Jae Jin Lee, Jongphil Kim, Jun-Min Zhou, Fabio Gomes, Marina Sehovic, Martine Extermann
BACKGROUND: Studies of older patients with colorectal cancer(CRC) have found inconsistent results about the correlation of various comorbidities with overall survival(OS) and treatment tolerance. To refine our understanding, we evaluated this correlation using the Cumulative Illness Rating Scale-Geriatric(CIRS-G) and heat maps to identify subgroups with the highest impact. METHODS: We retrospectively reviewed 153 patients aged 65 years and older with stage IV CRC undergoing chemotherapy...
February 11, 2019: Journal of Geriatric Oncology
Anao Zhang, Dexia Kong, Lin Jiang, Fei Sun, Ruth E Dunkle, Chun Liu
Background and Objectives: There exists an imperative need to comprehensively evaluate the effectiveness of psychosocial interventions for Chinese geriatric populations' mental wellbeing. This study conducted a systematic review and meta-analysis of psychosocial services for Chinese older adults' depression and anxiety. Research Design and Methods: A search of nine electronic databases, five geriatric mental health journals, and reference lists was conducted for studies published between 1980 and April...
February 7, 2019: Gerontologist
Barbara J Zarowitz, James E Tisdale
BACKGROUND: The exponential increase in the number of medications associated with clinically important prolongation of the heart rate-corrected QT interval (QTc) places older adults at increased risk of arrhythmias including life-threatening torsade de pointes (TdP) and sudden death. Risk factors, other than age older than 65 years and female sex, include multiple concurrent drugs that prolong QTc and a variety of underlying predisposing conditions. Although electronic medical records and pharmacy dispensing systems can alert clinicians to the risk of QTc-prolonging therapy, more than 95% of safety alerts are overridden, and many systems have deactivated QTc drug interaction alerts...
February 12, 2019: Journal of the American Geriatrics Society
Ashley M Campbell, Kim C Coley, Jason M Corbo, Teresa M DeLellis, Matthew Joseph, Carolyn T Thorpe, Melissa S McGivney, Patricia Klatt, Lora Cox-Vance, Vincent Balestrino, Heather Sakely
Background: Drug therapy problems, which are adverse events involving medications that can ultimately interfere with a patient's therapeutic goals, occur frequently in older adults. If not identified, resolved, and prevented through clinical decision-making, drug therapy problems may negatively affect patient health outcomes. Objective: To quantify the impact of pharmacist interventions on the care of older adults by identifying the most common drug therapy problems, the medications most often involved in these problems, and the actions taken by pharmacists to resolve these problems...
December 2018: American Health & Drug Benefits
Kerstin Bitter, Christina Pehe, Manfred Krüger, Gabriela Heuer, Regine Quinke, Ulrich Jaehde
BACKGROUND: The benefit of medication reviews for long-term care (LTC) residents has been generally recognized throughout health care systems. Whereas many studies showed the impact of comprehensive medication reviews performed by specialized clinical pharmacists, little is known about the impact of medication reviews performed by community pharmacists. Involving them in the provision of medication reviews may help satisfy the increasing demand for ensuring medication safety. METHODS: Community pharmacists supplying drugs to the LTC facilities performed a medication review for German LTC residents aged at least 65 years and taking five or more drugs per day based on the patients' medication only...
February 11, 2019: BMC Geriatrics
Jürgen M Bauer, Michael Denkinger, Sebastian Voigt-Radloff, Hans Jürgen Heppner
No abstract text is available yet for this article.
February 8, 2019: Zeitschrift Für Gerontologie und Geriatrie
Chi-Hsien Huang, Hiroyuki Umegaki, Yuuki Watanabe, Hiroko Kamitani, Atushi Asai, Shigeru Kanda, Hideki Nomura, Masafumi Kuzuya
BACKGROUND: Although potentially inappropriate medications (PIMs) have been linked to poor health outcomes, country-specific PIM criteria have not been compared. Thus, we compared the identification of PIMs between the Screening Tool for Older Person's Appropriate Prescriptions for Japanese (STOPP-J) and the 2015 American Geriatrics Society Beers Criteria in elderly patients receiving home-based medical services. METHODS: A 5-year prospective cohort study was conducted with 196 patients receiving home-based medical services...
2019: PloS One
G Guaraldi, S Marcotullio, R Maserati, M Gargiulo, J Milic, I Franconi, A Chirianni, M Andreoni, M Galli, A Lazzarin, A D'Arminio Monforte, G Di Perri, C-F Perno, M Puoti, S Vella, A Di Biagio, L Maia, C Mussi, M Cesari, A Antinori
OBJECTIVE: This article deals with the attempt to join HIV and geriatric care management in the 2017 edition of the Italian guidelines for the use of antiretrovirals and the diagnostic-clinical management of HIV-1 infected persons. METHODS: The outlined recommendations are based on evidence from randomized clinical trials and observational studies published in peer-reviewed journals and/or presented at international scientific conferences in recent years. The principles of starting antiretroviral therapy in elderly patients and the viro-immunological goals are the same as in the general HIV population...
2019: Journal of Frailty & Aging
Jyoti Sharma, Manisha Parulekar, Peter Stewart, Melissa Blatt, Tania Zielonka, Themba Nyirenda, Christopher Rogers, Lisa Tank
Background Traumatic injury in a growing geriatric population is associated with higher mortality and complication rates. Geriatric consultation (GC) is vital in reducing risk factors that contribute to adverse outcomes. This study aims to determine if receiving a GC had an impact on high-risk medication usage. Methods Patients eligible for a GC, age ≥ 65, and length of stay > two days, were identified via a chart review from July 2013 to July 2014 at a Level II trauma center. This population was divided into those with and without a GC...
November 28, 2018: Curēus
Mohit Bhandari, Winni Mathur, Mathias Fobi, Susmit Kosta
BACKGROUND: Obesity is an epidemic with an increasing incidence in geriatric individuals also. The aim of the present study is to determine the outcomes in geriatric patients ≥ 65 years, who underwent Bariatric Surgery. MATERIAL AND METHODS: A retrospective review was performed of prospectively collected data on geriatric patients (age 65 to 80 years) who had undergone bariatric surgery at a single institution from Jan. 2010 to Dec. 2013. A cohort of adult patients (age 17 to 64 years) were matched for comparative evaluation who also underwent bariatric surgery in the same period...
February 5, 2019: Obesity Surgery
John Williams, Felix Allen, Marta Kedrzycki, Yathish Shenava, Renu Gupta
Introduction: The National Institute of Health and Clinical Excellence guidelines in the United Kingdom recommend magnetic resonance imaging (MRI) as the first-line investigation for radiographically occult hip fractures, if available within 24 hours. In our department, however, multislice computerized tomography (MSCT) is instead used as a first-line investigation due to significant delays associated with obtaining MRI. Our aim was to determine the validity and practicality of MSCT for diagnosis of occult hip fractures and its impact on timing of surgery...
2019: Geriatric Orthopaedic Surgery & Rehabilitation
Olivia Le Saux, Claire Falandry, Hui K Gan, Benoit You, Gilles Freyer, Julien Péron
BACKGROUND: The objective of this study was to describe the implementation of comprehensive geriatric assessment (CGA) in clinical trials dedicated to older patients before and after the creation of the International Society of Geriatric Oncology in the early 2000s. SUBJECTS, MATERIALS, AND METHODS: All phase I, II, and III trials dedicated to the treatment of cancer among older patients published between 2001 and 2004 and between 2011 and 2014 were reviewed. We considered that a CGA was performed when the authors indicated an intention to do so in the Methods section of the article...
February 1, 2019: Oncologist
Lasse T Krogsbøll, Karsten Juhl Jørgensen, Peter C Gøtzsche
BACKGROUND: General health checks are common elements of health care in some countries. They aim to detect disease and risk factors for disease with the purpose of reducing morbidity and mortality. Most of the commonly used individual screening tests offered in general health checks have been incompletely studied. Also, screening leads to increased use of diagnostic and therapeutic interventions, which can be harmful as well as beneficial. It is therefore important to assess whether general health checks do more good than harm...
January 31, 2019: Cochrane Database of Systematic Reviews
Guilherme Eustáquio Furtado, Rubens Letieri, Eef Hogervorst, Ana Botelho Teixeira, José Pedro Ferreira
The purpose of present study was to analyze the magnitude of the effect-size in the assessment of the cognitive status of populations over 60 years of age. The search strategy included PubMed, B-on, Ebsco, Ebsco Health, Scielo, Eric, Lilacs and Sportdiscus data bases. Only observational, cohort and cross-sectional studies were included in the meta-analysis. The central descriptors were elderly-frail, older adults, cognition and geriatric assessment and other additional terms. After applying the additional search criteria, 12 manuscripts were selected from an initial universe of 1,078 identified...
January 2019: Ciência & Saúde Coletiva
Doris Y P Leung, Helen Y L Chan, Susan Z M Yau, Patrick K C Chiu, Fiona W K Tang, Joseph S K Kwan
AIM: To examine the effect of a video-supported nurse-led advance care planning to frail geriatric patients on end-of-life decision making outcomes in patients and their carers. DESIGN: This is a double-blinded randomized controlled trial with parallel arms. METHODS: The protocol was approved by the Institutional Review Board of the participating hospital on 1 August 2018. Frail elders and their carer if any are enrolled during hospitalization, and undergo randomization after discharged...
January 29, 2019: Journal of Advanced Nursing
Zachary T Young, Michaela Close, Fernando A Herrera
BACKGROUND: The purpose of this study was to identify preoperative risk factors in patients undergoing reduction mammoplasty as well as identify any increased complication risk in patients older than 60 years undergoing reduction mammoplasty. METHODS: The American College of Surgeons National Surgical Quality Improvement Program data from years 2013-2015 was reviewed. Patients were identified using Current Procedural Terminology code 19318 specific for reduction mammoplasty...
January 28, 2019: Annals of Plastic Surgery
Stefanie Thevelin, Leïla El Mounaouar, Sophie Marien, Benoit Boland, Séverine Henrard, Olivia Dalleur
BACKGROUND: Older persons are at significant risk of drug-related admissions (DRAs). We previously demonstrated that 27% of hospitalizations in geriatric patients were associated with potentially inappropriate medicines (PIMs) and/or potential prescribing omissions (PPOs) identified by the Screening Tool of Older People's Prescriptions/Screening Tool to Alert to Right Treatment (STOPP/START) criteria version 1 (v1 ). The updated STOPP/START criteria version 2 (v2 ) comprised a 31% increase in prescribing criteria...
January 29, 2019: Drugs & Aging
Camille P Vaughan, William Dale, Heather G Allore, Ellen F Binder, Cynthia M Boyd, Julie P W Bynum, Jerry H Gurwitz, Nancy E Lundebjerg, Daniel E Trucil, Mark A Supiano, Cathleen Colón-Emeric
After passage of the 21st Century Cures Act, the National Institutes of Health held a workshop in 2017 to consider expanding its inclusion policy to encompass individuals of all ages. American Geriatrics Society (AGS) leaders and members participated in the workshop and formal feedback period. AGS advocacy clearly impacted the resulting workshop report and Inclusion Across the Lifespan policy that eliminates upper-age limits for research participation unless risk justified and changes the language used to describe older adults and other vulnerable groups...
January 29, 2019: Journal of the American Geriatrics Society
Arti Hurria, Christopher R Carpenter, Frances McFarland, Nancy E Lundebjerg, Rafael de Cabo, Luigi Ferrucci, Stephanie A Studenski, Nir Barzilai, Josephine P Briggs, Joachim H Ix, Dalane W Kitzman, George A Kuchel, Nicolas Musi, John C Newman, Thomas A Rando, Alexander K Smith, Jeremy D Walston, James L Kirkland, Raymond Yung
The American Geriatrics Society convened a conference in Bethesda, Maryland, to explore models and studies of aging. This was the second of three conferences, supported by a U13 grant from the National Institute on Aging, to aid recipients of Grants for Early Medical/Surgical Specialists Transition to Aging Research (GEMSSTAR) in integrating geriatrics into their specialties. Recognizing that aging is the largest risk factor for multiple chronic diseases and age-related loss of resilience, the conference organizers focused scientific sessions on how targeting age-related mechanisms can delay, prevent, or reverse geriatric syndromes, age-related chronic diseases, and loss of resilience...
January 29, 2019: Journal of the American Geriatrics Society
(no author information available yet)
The American Geriatrics Society (AGS) Beers Criteria® (AGS Beers Criteria®) for Potentially Inappropriate Medication (PIM) Use in Older Adults are widely used by clinicians, educators, researchers, healthcare administrators, and regulators. Since 2011, the AGS has been the steward of the criteria and has produced updates on a 3-year cycle. The AGS Beers Criteria® is an explicit list of PIMs that are typically best avoided by older adults in most circumstances or under specific situations, such as in certain diseases or conditions...
January 29, 2019: Journal of the American Geriatrics Society
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