keyword
https://read.qxmd.com/read/37604748/early-predictors-of-prolonged-intensive-care-utilization-following-liver-transplantation
#21
JOURNAL ARTICLE
Hunter B Moore, Wells LaRiviere, Ivan Rodriguez, Kristen Brown, Kyndall Hadley, James J Pomposelli, Megan A Adams, Michael E Wachs, Kendra D Conzen, Peter T Kennealey, Bruce Kaplan, Elizabeth A Pomfret, Trevor L Nydam
INTRODUCTION: Creatinine, bilirubin, and fibrinolysis resistance are associated with multi-organ dysfunction and likely risk factors for prolonged intensive care unit (pICU) stay following liver transplantation (LT). We hypothesize postoperative day-1 (POD-1) labs will predict pICU. METHODS: LT recipients had clinical laboratories and viscoelastic testing with tissue plasminogen activator thrombelastography (tPA TEG) to quantify fibrinolysis resistance (LY30) on POD-1...
July 13, 2023: American Journal of Surgery
https://read.qxmd.com/read/37565011/predictors-of-failure-of-noninvasive-ventilation-in-critically-ill-children
#22
JOURNAL ARTICLE
Alyson K Baker, Andrew L Beardsley, Brian D Leland, Elizabeth A Moser, Riad L Lutfi, A Ioana Cristea, Courtney M Rowan
Noninvasive ventilation (NIV) is a common modality employed to treat acute respiratory failure. Most data guiding its use is extrapolated from adult studies. We sought to identify clinical predictors associated with failure of NIV, defined as requiring intubation. This single-center retrospective observational study included children admitted to pediatric intensive care unit (PICU) between July 2014 and June 2016 treated with NIV, excluding postextubation. A total of 148 patients was included. Twenty-seven (18%) failed NIV...
September 2023: Journal of Pediatric Intensive Care
https://read.qxmd.com/read/37505408/recurrent-guillain-barr%C3%A3-syndrome-clinical-profile-and-outcome
#23
JOURNAL ARTICLE
K C Sudeep, Arun Bansal, Manjinder Singh Randhawa, Jayashree Muralidharan, Karthi Nallasamy, Suresh Kumar Angurana, Naveen Sankhyan
OBJECTIVES: To compare clinical, neurological, treatment and outcome of recurrent Guillian-Barré Syndrome (GBS) with non-recurrent GBS. Also, to compare different episodes of recurrent GBS. METHODS: The patient's case records were retrieved retrospectively from the electronic database and case record files. Clinical profile, nerve conduction study, treatment, and outcome details of children with a diagnosis of GBS admitted in Pediatric Intensive Care Unit (PICU) from 2010 to March 2022 were screened...
July 28, 2023: Indian Journal of Pediatrics
https://read.qxmd.com/read/37462437/performance-of-tools-and-measures-to-predict-fluid-responsiveness-in-pediatric-shock-and-critical-illness-a-systematic-review-and-meta-analysis
#24
JOURNAL ARTICLE
Sarah B Walker, Jessica M Winters, Jacob M Schauer, Peggy Murphy, Andrea Fawcett, L Nelson Sanchez-Pinto
OBJECTIVES: In this systematic review and meta-analysis we asked: Do predictors of fluid responsiveness in children perform comparably: 1) in the PICU as in non-PICU settings? 2) in shock states compared with nonshock states? Additionally, 3) is there an association between preload responsiveness and clinical response? DATA SOURCES: Ovid Medline, PubMed, and Embase databases were searched from inception through May 2022. STUDY SELECTION: Included studies reported physiological response to IV fluid administration in humans less than 18 years...
July 18, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/37458817/acute-kidney-injury-in-pediatric-toxic-shock-syndrome-is-associated-with-worse-clinical-course-in-the-intensive-care-unit
#25
JOURNAL ARTICLE
Avichai Weissbach, Eytan Kaplan, Gili Kadmon, Yulia Gendler, Elhanan Nahum, Barak Meidan, Shirley Friedman, Efraim Sadot, Itay Ayalon
To explore the prevalence, severity, nature, and significance of acute kidney injury (AKI) among children admitted to the pediatric intensive care unit (PICU) with toxic shock syndrome (TSS). Bi-center, retrospective observational study. Children admitted for TSS to two intensive care units from 2009-2022 were included. We identified 41 children (median age 5 years, 46% females) who met the Centers for Disease Control and Prevention (CDC) definitions of TSS. Staphylococcal TSS accounted for 63% of the patients and Streptococcal TSS accounted for the remaining 37%...
July 17, 2023: European Journal of Pediatrics
https://read.qxmd.com/read/37434832/a-new-nomogram-for-the-individualized-prediction-of-children-s-mortality-risk-in-pediatric-intensive-care-unit
#26
JOURNAL ARTICLE
Chaoyan Yue, Chunyi Zhang, Chunmei Ying
OBJECTIVE: We developed a new nomogram for the prediction of mortality risk in children in pediatric intensive care units (PICU). METHODS: We conducted a retrospective analysis using the PICU Public Database, a study that included a total of 10,538 children, to develop a new risk model for mortality in children in the intensive care units (ICU). The prediction model was analyzed using multivariate logistic regression with predictors including age and physiological indicators, and the prediction model was presented as a nomogram...
2023: American Journal of Translational Research
https://read.qxmd.com/read/37416842/urinary-tissue-inhibitor-of-metalloproteinase-2-as-an-early-predictor-for-acute-kidney-injury-in-critically-ill-children
#27
JOURNAL ARTICLE
Maha A Abouhadid, Tarek A Abdel Gawad, Howida H El Gebaly, Azza A Abdallah, Amira S El Refay, Neveen M Helmy, Ahmad M Allam
OBJECTIVES: Acute kidney injury (AKI) is one of the most devastating complications of critical illness in children. Serum creatinine (Scr) is considered the gold standard for AKI diagnosis yet noted to be late and inaccurate. This raises the need for an early and accurate biochemical parameter for the early detection of AKI. This research aimed to explore the role of urinary tissue inhibitor metalloproteinase 2 (TIMP-2) in the early prediction of AKI, compared to standard biomarkers, in critically ill children admitted to pediatric intensive care unit (PICU)...
2023: International Journal of Health Sciences
https://read.qxmd.com/read/37398718/the-various-scoring-systems-in-pediatric-intensive-care-units-a-prospective-observational-study
#28
JOURNAL ARTICLE
Jyotsna, Rakesh Kumar, Shambhavi Sharan, Sunil Kishore, Jayant Prakash
BACKGROUND: The discrimination power of the pediatric risk of mortality (PRISM), pediatric index of mortality (PIM), sequential organ failure assessment (SOFA), and pediatric logistic organ dysfunction (PELOD) may not always be true for countries such as India due to differences in factors from those nations where these scoring systems were validated. Therefore, this study was undertaken to determine and compare severity, course of illness, and outcomes in critically ill children admitted to the pediatric intensive care unit (PICU) using different scoring systems such as PRISM 4, PIM 3, PELOD 2, and the pediatric sequential organ failure assessment (pSOFA ) score, and to analyze the clinical spectrum and demographic profile of children admitted to the PICU...
May 2023: Curēus
https://read.qxmd.com/read/37371217/individualized-goal-setting-for-pediatric-intensive-care-unit-based-rehabilitation-using-the-canadian-occupational-performance-measure
#29
JOURNAL ARTICLE
Youngsub Hwang, Jeong-Yi Kwon, Joongbum Cho, Jaeyoung Choi
The Canadian Occupational Performance Measure (COPM) is a client-centered outcome measure that facilitates the prioritization of individualized interventions. Given the rising emphasis on individualized intervention in pediatric intensive care units (PICUs), this cross-sectional study aimed to explore caregivers' perspectives on their children's functional goals within PICUs. From 1 September 2020 to 26 June 2022, caregivers of 41 children aged 1-18 years completed the COPM within 48 h of PICU admission. The study also explored the clinical variables predicting a high number of occupational performance goals (≥4/5)...
May 31, 2023: Children
https://read.qxmd.com/read/37334038/predictors-of-neurocognitive-and-psychological-disorders-in-children-after-intensive-care-admission-a-prospective-cohort-study
#30
JOURNAL ARTICLE
Saptadi Yuliarto, Ardhanis Ramadhanti, Takhta Khalasha, Kurniawan Taufiq Kadafi, Ariani Ariani
BACKGROUND AND AIMS: Children admitted in the pediatric intensive care unit (PICU) often deal with long-term morbidities affecting physical, cognitive, emotional, social, and psychiatric symptoms. We aimed to identify the internal and external factors which predict the occurrence of neurocognitive and psychological disorders in survivors at 3 months after PICU discharge. METHODS: We identified 53 critically ill children, ages 4-18 years old, admitted in PICU for more than 24 h, and survived...
June 2023: Health Science Reports
https://read.qxmd.com/read/37274988/implications-of-rigid-bronchoscopy-an-eight-year-review-in-a-pediatric-intensive-care-unit
#31
JOURNAL ARTICLE
Talal Al-Khatib
INTRODUCTION: Rigid bronchoscopy is an endoscopic technique used to visualize the airway, and rigid bronchoscopy is performed for both diagnostic and therapeutic indications. We defined the clinical characteristics of pediatric intensive care unit (PICU) patients undergoing bronchoscopy to establish a predictive model for early discharge from the PICU. Prediction can provide tangible aid in managing PICU patients. OBJECTIVES: The primary objectives of this research are to evaluate the impact of different bronchoscopic procedures on the duration of PICU stay and to determine the Predictors of PICU discharge...
June 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/37252470/ventilator-associated-pneumonia-in-paediatric-intensive-care-unit-patients-microbiological-profile-risk-factors-and-outcome
#32
JOURNAL ARTICLE
Piyali Bhattacharya, Arvind Kumar, Sanat Kumar Ghosh, Sudesh Kumar
Introduction Ventilator-associated pneumonia (VAP) is one of the dreaded events in sick children who are ventilated in the paediatric intensive care unit (PICU) and has a high mortality rate. So, there is a need to know the causative organisms, risk factors, and possible predictors in a particular PICU for prevention, early identification, and treatment to decrease morbidity and mortality. This study was planned with the objectives to determine the microbiological profile, associated risk factors, and outcome of VAP in children...
April 2023: Curēus
https://read.qxmd.com/read/37221576/phase-angle-as-a-prognostic-indicator-in-critically-ill-children-a-systematic-review
#33
REVIEW
Luna D A Oliveira, Julia C Ventura, Daniela B Hauschild, Yara M F Moreno
Phase angle (PhA) may reflect the integrity of cellular membranes, hydration status, and total body cell mass. Studies have shown that PhA can be used as a good predictor for evaluation of disease severity in critically ill adults. However, there is a lack of studies assessing the association between PhA and clinical outcomes in critically ill children. This systematic review described the association between PhA at pediatric intensive care unit (PICU) admission with clinical outcomes in critically ill children...
May 23, 2023: Nutrition in Clinical Practice
https://read.qxmd.com/read/37218230/a-relation-between-serum-albumin-level-and-prognosis-of-critically-ill-children-admitted-to-the-paediatric-intensive-care-unit
#34
JOURNAL ARTICLE
Murtaza Ali Gowa, Usman Tauseef, Syed Habib Ahmed
OBJECTIVE: To determine the frequency of hypoalbuminaemia in critically ill children, and to assess the association of low serum albumin with clinical deterioration and outcome. METHODS: The prospective, descriptive study was conducted from September 1, 2020, to October 31, 2021, at the National Institute of Child Health, Karachi, and comprised critically ill children of either gender aged between 3 months and 16 years admitted to the paediatric intensive care unit...
May 2023: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/37185836/peripheral-blood-parameters-for-predicting-picu-admission-and-mechanical-ventilation-in-pediatric-inpatients-with-human-parainfluenza-virus-induced-pneumonia
#35
JOURNAL ARTICLE
Fu-Lu Chu, Chen Li, Yiqing Liu, Bo Dong, Yang Qiu, Gang Fan
Human parainfluenza viruses (hPIVs)-induced pneumonia is an important cause of pediatric hospitalization, and some develop severe pneumonias requiring pediatric intensive care unit (PICU) admission and mechanical ventilation (MV). The aim of this study is to investigate the value of peripheral blood (PB) parameters available on admission in predicting the need for PICU admission and MV due to pneumonia caused by hPIVs. A total of 331 cases including 277 (83.69%) on the general ward (GW) and 54 (16.31%) on the PICU were enrolled between January 2016 and June 2021...
April 2023: Journal of Medical Virology
https://read.qxmd.com/read/37082472/can-lactate-clearance-predict-mortality-in-critically-ill-children
#36
JOURNAL ARTICLE
Azza A Moustafa, Abeer S Elhadidi, Mona A El-Nagar, Hadir M Hassouna
Serial evaluation of blood lactate, including lactate clearance, may have greater value over single measurement at the time of presentation. The rationale of the current study was to evaluate the use of lactate clearance after 6 hours of admission to pediatric intensive care unit (PICU) as a predictor of mortality in critically ill children. A prospective observational study was conducted in a nine-bed PICU of a tertiary care teaching hospital over a period of 6 months. Lactate levels were measured in arterial blood samples of 76 patients at the time of admission and 6 hours later...
June 2023: Journal of Pediatric Intensive Care
https://read.qxmd.com/read/37082464/point-of-care-ultrasound-measurement-of-diaphragm-thickening-fraction-as-a-predictor-of-successful-extubation-in-critically-ill-children
#37
JOURNAL ARTICLE
Swathy Subhash, Vasanth Kumar
Ventilation-induced diaphragm dysfunction can delay weaning from mechanical ventilation. Identifying the optimal time for extubation has always been a challenge for intensivists. Diaphragm ultrasound is gaining immense popularity as a surrogate to measure diaphragm function. We attempted to assess the utility of diaphragm function in predicting extubation success using point-of-care ultrasound examination. We conducted a prospective observational study in a single-center tertiary care pediatric intensive care unit (PICU)...
June 2023: Journal of Pediatric Intensive Care
https://read.qxmd.com/read/37079697/evaluation-of-the-renal-angina-index-to-predict-the-development-of-acute-kidney-injury-in-children-with-sepsis-who-live-in-middle-income-countries
#38
JOURNAL ARTICLE
María Del Pilar Suárez, Jaime Fernández-Sarmiento, Luz Esthella González, Mayerly Prada Rico, Juan Sebastián Barajas, Ricardo Gastelbondo Amaya
OBJECTIVE: The renal angina index (RAI) provides a clinically feasible and applicable tool to identify critically ill children at risk of severe acute kidney injury (AKI) in high-income countries. Our objective was to evaluate the performance of the RAI as a predictor of the development of AKI in children with sepsis in a middle-income country and its association with unfavorable outcomes. METHODS: This is a retrospective cohort study in children with sepsis hospitalized in the pediatric intensive care unit (PICU) between January 2016 and January 2020...
April 21, 2023: Pediatric Emergency Care
https://read.qxmd.com/read/37026721/unplanned-extubations-requiring-reintubation-in-pediatric-critical-care-an-epidemiological-study
#39
JOURNAL ARTICLE
Krista Wollny, Deborah McNeil, Stephana J Moss, Tolulope Sajobi, Simon J Parsons, Karen Benzies, Amy Metcalfe
OBJECTIVES: Unplanned extubations are an infrequent but life-threatening adverse event in pediatric critical care. Due to the rarity of these events, previous studies have been small, limiting the generalizability of findings and the ability to detect associations. Our objectives were to describe unplanned extubations and explore predictors of unplanned extubation requiring reintubation in PICUs. DESIGN: Retrospective observational study and multilevel regression model...
April 1, 2023: Pediatric Critical Care Medicine
https://read.qxmd.com/read/36973036/outcome-of-noninvasive-respiratory-support-in-pediatric-high-dependency-units-for-acute-respiratory-distress
#40
JOURNAL ARTICLE
Khaloud S Al-Mukhaini, Samiuddin Shaikh, Ahmed K Al-Kharusi, Saif Sa Thani, Raghad M Al-Abdwani, Omar A Al-Senaidi, Ahmed E Elkhamisy, Florence D Birru, Amna A Al-Fahdi
BACKGROUND: Noninvasive respiratory support (NRS) is widely used in pediatric ICUs (PICUs). However, there is limited experience regarding the utilization of NRS in non-PICU settings. We aimed to evaluate the success rate of NRS in pediatric high-dependency units (PHDUs), identify predictors of NRS failure, quantify adverse events, and assess outcomes. METHODS: We included infants and children (> 7 d to < 13 y old) admitted to PHDU in 2 tertiary hospitals for acute respiratory distress over a 19-month period...
September 2023: Respiratory Care
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