Victoria Bitsadze, Fidan Yakubova, Jamilya Khizroeva, Arina Lazarchuk, Polina Salnikova, Alexander Vorobev, Maria Tretyakova, Natalia Degtyareva, Kristina Grigoreva, Nilufar Gashimova, Margaret Kvaratskheliia, Nataliya Makatsariya, Ekaterina Kudryavtseva, Anna Tomlenova, Jean-Christophe Gris, Ismail Elalamy, Cihan Ay, Alexander Makatsariya
Unlike classic APS, CAPS causes multiple microthrombosis due to an increased inflammatory response, known as a "thrombotic storm". CAPS typically develops after infection, trauma, or surgery and begins with the following symptoms: fever, thrombocytopenia, muscle weakness, visual and cognitive disturbances, abdominal pain, renal failure, and disseminated intravascular coagulation. Although the presence of antiphospholipid antibodies in the blood is one of the diagnostic criteria, the level of these antibodies can fluctuate significantly, which complicates the diagnostic process and can lead to erroneous interpretation of rapidly developing symptoms...
January 4, 2024: International Journal of Molecular Sciences