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https://read.qxmd.com/read/30786144/wse-2-photovoltaic-device-based-on-intramolecular-p-n-junction
#1
Yicheng Tang, Zhen Wang, Peng Wang, Feng Wu, Yueming Wang, Yunfeng Chen, Hailu Wang, Meng Peng, Chongxin Shan, Zhihong Zhu, Shiqiao Qin, Weida Hu
High quality p-n junctions based on 2D layered materials (2DLMs) are urgent to exploit, because of their unique properties such as flexibility, high absorption, and high tunability which may be utilized in next-generation photovoltaic devices. Based on transfer technology, large amounts of vertical heterojunctions based on 2DLMs are investigated. However, the complicated fabrication process and the inevitable defects at the interfaces greatly limit their application prospects. Here, an in-plane intramolecular WSe2 p-n junction is realized, in which the n-type region and p-type region are chemically doped by polyethyleneimine and electrically doped by the back-gate, respectively...
February 20, 2019: Small
https://read.qxmd.com/read/30785753/methylsulfonylated-polyketides-produced-by-neosartorya-udagawae-hdn13-313-via-exogenous-addition-of-small-molecules
#2
Guihong Yu, Qiuying Wang, Shan Liu, Xiaomin Zhang, Qian Che, Guojian Zhang, Tianjiao Zhu, Qianqun Gu, Dehai Li
Two new polyketides modified with a rare methylsulfonyl group, 3-methoxy-6-methyl-5-(methylsulfonyl)benzene-1,2,4-triol (1) and neosartoryone A (2), along with a biogenetically related compound (3), were isolated from Neosartorya udagawae HDN13-313 cultivated with the DNA methyltransferase inhibitor 5-azacytidine. The methylsulfonyl group of 1 and 2 was proven to be derived from DMSO, which was used as the solvent to dissolve 5-azacytidine. This is the first report of a fungus that can achieve a sulfonylation-like modification of natural products utilizing DMSO as a sulfur source...
February 20, 2019: Journal of Natural Products
https://read.qxmd.com/read/30785389/streptococcus-chenjunshii-sp-nov-isolated-from-feces-of-tibetan-antelopes
#3
Zhi Tian, Shan Lu, Dong Jin, Jing Yang, Ji Pu, Xin-He Lai, Xiang-Ning Bai, Xiao-Min Wu, Junqin Li, Suping Wang, Jianguo Xu
Three Gram-stain-positive, catalase-negative, α-haemolytic, chain-forming and coccus-shaped microorganisms (strains Z15T , Z1 and Z2) were isolated from feces of Tibetan antelopes collected from the Qinghai-Tibet plateau, PR China. The results of 16S rRNA gene sequence studies indicated that Z15T shared 94.5, 93.1 and 92.2 % similarity with Streptococcus pantholopis DSM 102135T , Streptococcus ursoris NUM 1615T and Streptococcus dentapri NUM 1529T , respectively. rpoB and groEL-based sequence analysis of our three novel isolates revealed interspecies divergence of 16...
February 20, 2019: International Journal of Systematic and Evolutionary Microbiology
https://read.qxmd.com/read/30784931/alkaloids-from-nelumbinis-plumula-afnp-ameliorate-aortic-remodeling-via-rhoa-rock-pathway
#4
Qiongyu Li, Da Wo, Yue Huang, Na Yu, Jianwei Zeng, Hongwei Chen, Huai Wang, Liya Bao, Shan Lin, JianFeng Chu, Jun Peng
The protective role of alkaloids from Nelumbinis Plumula (AFNP) on the aorta during hypertension is not yet fully understood. We hypothesize that AFNP exerts protective effects against Ang II-induced hypertension by mediating RhoA/ROCK pathway and phenotypic switching during hypertension. In the present study, we evaluated the effect of AFNP on angiotensin II (Ang II)-induced actin cytoskeleton reorganization and aorta remodeling, as well as the involvement of RhoA/Rho-associated coiled kinase (ROCK) pathway in protecting against hypertension...
February 20, 2019: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://read.qxmd.com/read/30784757/the-structure-activity-relationship-sar-for-phthalate-mediated-developmental-and-reproductive-toxicity-in-males
#5
REVIEW
Xiaoheng Li, Jiaying Mo, Qiqi Zhu, Chaobo Ni, Yiyan Wang, Huitao Li, Zhen-Kun Lin, Ren-Shan Ge
Testicular dysgenesis syndrome includes the hypospadias, cryptorchidism and abnormal fetal testis in male neonate. This is possibly caused by the environmental phthalates, which down-regulate the expression of androgen synthetic genes and Insl3 or directly inhibits steroidogenic enzymes. There are distinct structure-activity relationships (SARs) for phthalate-mediated developmental and reproductive toxicity. Here, we review the SAR for phthalate-mediated testicular dysgenesis syndrome. Of phthalates of straight side chains, C5-C6 ones are the most potent, C4 or C7 are moderate, C3 is weakest, and C1-2 or C8-13 are ineffective...
February 15, 2019: Chemosphere
https://read.qxmd.com/read/30784451/the-balance-of-acidity-and-redox-capability-over-modified-ceo-2-catalyst-for-the-selective-catalytic-reduction-of-no-with-nh-3
#6
Zhihua Lian, Wenpo Shan, Meng Wang, Hong He, Qingcai Feng
The effect of acidity and redox capability over sulfuric acid-modified CeO2 catalysts were studied for the selective catalytic reduction of NOx with NH3 (NH3 -SCR). The deposition of sulfate significantly enhanced the catalytic performance over CeO2 . NOx conversion over 4H2 SO4 /CeO2 at 230-440 °C was higher than 90%. The strong redox capability of CeO2 could result in unselective NH3 oxidation and decrease high temperatures catalytic activity and N2 selectivity. The deposition of sulfate increased the acidity and weakened the redox capability, and then increased the high temperature NOx conversion and N2 selectivity...
May 2019: Journal of Environmental Sciences (China)
https://read.qxmd.com/read/30783928/acute-effects-of-uvb-radiation-on-the-survival-growth-development-and-reproduction-of-daphniopsis-tibetana-sars-crustacea-cladocera
#7
Meiru Wang, Wen Zhao, Jie Wei, Shan Wang, Xi Xie
Daphniopsis tibetana Sars lives in elevation, usually with strong solar UV radiation. We speculate that UV may have an effect on the ecology and evolutionary biology of this species. However, the regulatory effect and mechanism of UV on D. tibetana have not been studied previously. Here, our results showed that UVB could act as a positive factor in the relative body lengths, reproductive parameters, and population growth parameters of D. tibetana when UVB radiation is 20-170 mJ cm-2 , compared with the control group...
February 19, 2019: Environmental Science and Pollution Research International
https://read.qxmd.com/read/30783641/novel-superconducting-structures-of-bh-2-under-high-pressure
#8
Wen-Hua Yang, Wen-Cai Lu, Shan-Dong Li, Xu-Yan Xue, Qing-Jun Zang, K M Ho, C Z Wang
The crystal structures of boron hydrides in a pressure range of 50-400 GPa were studied using the genetic algorithm (GA) method combined with first-principles density functional theory calculations. BH4 and BH5 are predicted to be thermodynamically unstable. Two new BH2 structures with Cmcm and C2/c space group symmetries, respectively, were predicted, in which the B atoms tend to form two-dimensional sheets. The calculated band structures showed that in the pressure range of 50-150 GPa, the Cmcm-BH2 phase has very small gaps, while the C2/c-BH2 phase at 200-400 GPa is metallic...
February 20, 2019: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/30783421/protective-effect-of-xin-ji-er-kang-on-cardiovascular-remodeling-in-high-salt-induced-hypertensive-mice
#9
Guangyao Huang, Pan Cheng, Ling Ding, Li Wang, Juan Hu, Yongxue Zhang, Guowei Cai, Meiling Chen, Aizong Shen, Shan Gao
The aim of the present study was to investigate the effects of Xin-Ji-Er-Kang (XJEK) on high salt-induced hypertensive mice. Mice with high-salt diet-induced hypertension were divided into four groups: Control (standard diet alone for 8 weeks), model (diet containing 8% NaCl for 8 weeks and intragastric administration of distilled water for the last 4 weeks), XJEK + high-salt-treated (diet containing 8% NaCl for 8 weeks and intragastric administration of XJEK for the last 4 weeks) and irbesartan + high-salt-treated (diet containing 8% NaCl for 8 weeks with intragastric administration of irbesartan for the last 4 weeks)...
March 2019: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/30782965/proteolytic-processing-of-serk3-bak1-regulates-plant-immunity-development-and-cell-death
#10
Jinggeng Zhou, Ping Wang, Lucas A N Claus, Daniel Valentin Savatin, Guangyuan Xu, Shujing Wu, Xiangzong Meng, Eugenia Russinova, Ping He, Libo Shan
Plants have evolved many receptor-like kinases (RLKs) to sense extrinsic and intrinsic cues. The signaling pathways mediated by multiple leucine-rich repeat (LRR) RLK (LRR-RLK) receptors require ligand-induced receptor-coreceptor heterodimerization and transphosphorylation with BAK1/SERK family LRR-RLKs. Here we reveal an additional layer of regulation of BAK1 via a Ca2+-dependent proteolytic cleavage process that is conserved in Arabidopsis thaliana, Nicotiana benthamiana and Saccharomyces cerevisiae . The proteolytic cleavage of BAK1 is intrinsically regulated in response to developmental cues and immune stimulation...
February 19, 2019: Plant Physiology
https://read.qxmd.com/read/30782710/association-between-spinal-curvature-disorders-and-injury-a-nationwide-population-based-retrospective-cohort-study
#11
Yen-Liang Kuo, Chi-Hsiang Chung, Tsai-Wang Huang, Chang-Huei Tsao, Shan-Yueh Chang, Chung-Kan Peng, Wei-Erh Cheng, Wu-Chien Chien, Chih-Hao Shen
OBJECTIVES: Injury is an important issue in public health. Spinal curvature disorders are deformities characterised by excessive curves of the spine. The prevalence of spinal curvature disorders is not low, but its relationship with injury has not been studied. The aim of this study is to investigate whether spinal curvature disorders increase the risk of injury. DESIGN: Population-based retrospective cohort study. SETTING: Using data from the Taiwan National Health Insurance Research Database from 2000 to 2010...
January 17, 2019: BMJ Open
https://read.qxmd.com/read/30782426/assessing-the-change-of-anisometropia-in-unilateral-myopic-children-receiving-monocular-orthokeratology-treatment
#12
Wei-Shan Tsai, Jen-Hung Wang, Yuan-Chieh Lee, Cheng-Jen Chiu
BACKGROUND: This study aimed at comparing the inter-eye axial elongation difference in order to evaluate the change of anisometropia in unilateral myopic children wearing monocular orthokeratology (Ortho-K) lens. METHODS: In this retrospective cohort study, we recruited monocular myopic subjects treated with monocular Ortho-K lens from May 2012 to January 2017. The axial length (AL) of both eyes was recorded, and we calculated the AL difference as our primary outcome, to evaluate myopia progression...
February 16, 2019: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://read.qxmd.com/read/30782180/identity-blues-the-ethnobotany-of-the-indigo-dyeing-by-landian-yao-iu-mien-in-yunnan-southwest-china
#13
Shan Li, Anthony B Cunningham, Ruyan Fan, Yuhua Wang
BACKGROUND: Indigo-dyed textiles have been central to the cultural identity of Landian Yao (literally "blue clothes Yao") people in Southwest China for centuries, driving a significant local market for naturally dyed indigo cloth. In the past two decades, local indigo production for traditional textiles has declined for several reasons: Firstly, the younger generation of Landian Yao has shifted to using western style jeans and T-shirts. Secondly, due to its labor-intensive nature...
February 19, 2019: Journal of Ethnobiology and Ethnomedicine
https://read.qxmd.com/read/30782086/downregulation-of-microrna-125a-in-placenta-accreta-spectrum-disorders-contributes-antiapoptosis-of-implantation-site-intermediate-trophoblasts-by-targeting-mcl1
#14
Yongzhong Gu, Jinlai Meng, Changting Zuo, Shan Wang, Hongyan Li, Shigang Zhao, Tao Huang, Xietong Wang, Junhao Yan
The typical hallmark of placenta accreta spectrum (PAS) disorders is increased implantation site intermediate trophoblast (ISIT) cell numbers. However, the extent of trophoblast proliferation and apoptosis have not been found to differ from those of normal placentation. MicroRNA-125a (miR-125a) induces apoptosis in colon cancer cell by targeting myeloid cell leukemia-1 gene ( MCL1). We aimed to investigate the influence of miR-125a on ISIT cells in PAS disorders in 15 patients (self-paired trials) with placenta previa and PAS disorders...
February 19, 2019: Reproductive Sciences
https://read.qxmd.com/read/30781608/9-methylfascaplysin-is-a-more-potent-a%C3%AE-aggregation-inhibitor-than-the-marine-derived-alkaloid-fascaplysin-and-produces-nanomolar-neuroprotective-effects-in-sh-sy5y-cells
#15
Qingmei Sun, Fufeng Liu, Jingcheng Sang, Miaoman Lin, Jiale Ma, Xiao Xiao, Sicheng Yan, C Benjamin Naman, Ning Wang, Shan He, Xiaojun Yan, Wei Cui, Hongze Liang
β-Amyloid (Aβ) is regarded as an important pathogenic target for Alzheimer's disease (AD), the most prevalent neurodegenerative disease. Aβ can assemble into oligomers and fibrils, and produce neurotoxicity. Therefore, Aβ aggregation inhibitors may have anti-AD therapeutic efficacies. It was found, here, that the marine-derived alkaloid, fascaplysin, inhibits Aβ fibrillization in vitro . Moreover, the new analogue, 9-methylfascaplysin, was designed and synthesized from 5-methyltryptamine. Interestingly, 9-methylfascaplysin is a more potent inhibitor of Aβ fibril formation than fascaplysin...
February 18, 2019: Marine Drugs
https://read.qxmd.com/read/30779855/infant-withdrawal-and-behavior-problems-in-urban-chinese-toddlers-roles-of-maternal-sensitivity-to-infant-distress-and-emerging-delay-ability
#16
Xi Liang, Min Liu, Meifang Wang, Jie Yu, Zhengyan Wang, Shan Lu
Using a longitudinal design, this study examined the associations between infant temperamental withdrawal and behavior problems during toddlerhood and tested the moderating effects of maternal sensitivity to infant distress (MSID) and toddlers' ability to delay gratification (ADG) in urban Chinese families. Participants were 84 Chinese children (37 boys, 47 girls) and their mothers. When the infants were 6 months old (T1: infancy), their mothers reported their temperamental withdrawal, and research assistants observed and coded MSID by using a subscale of the Maternal Behavior Q-Sort during free-play interaction...
February 19, 2019: Infant Mental Health Journal
https://read.qxmd.com/read/30779845/a-high-fat-diet-aggravates-osteonecrosis-through-a-macrophage-derived-il-6-pathway
#17
Zubin Zhou, Chenhao Pan, Nan Wang, Lihui Zhou, Haojie Shan, Youshui Gao, Xiaowei Yu
Inflammation plays an important role in osteonecrosis. Obesity, a risk factor for osteonecrosis, leads to a chronic inflammatory status. We hypothesized that inflammation mediated the effects of obesity on osteonecrosis and tested our hypothesis in a mouse model of osteonecrosis. We fed mice with a high-fat diet (HFD) for 12 weeks before osteonecrosis induction by methylprednisolone and examined bone structure and IL-6 expression. Then we investigated the effects of IL-6 deletion in mice with osteonecrosis on the HFD...
February 19, 2019: International Immunology
https://read.qxmd.com/read/30779804/helicobacter-pylori-infection-increases-risk-of-incident-metabolic-syndrome-and-diabetes-a-cohort-study
#18
Yuan-Yuei Chen, Wen-Hui Fang, Chung-Ching Wang, Tung-Wei Kao, Yaw-Wen Chang, Chen-Jung Wu, Yi-Chao Zhou, Yu-Shan Sun, Wei-Liang Chen
Emerging studies have shed light on the association between Helicobacter pylori (HP) infection and cardiometabolic risk. However, there is no evidence to support a causal link for the relationship in the general population. Our aim was to determine whether HP infection is associated with the risks of incident type II diabetes mellitus (DM) in a population-based cohort consisting of adults from the general population. A total of 69235 adults enrolled in the study obtained health examinations at the Tri-Service General Hospital in Taiwan from 2010 to 2016...
2019: PloS One
https://read.qxmd.com/read/30779587/phonon-polariton-assisted-infrared-nano-imaging-of-local-strain-in-hexagonal-boron-nitride
#19
Bosai Lyu, Hongyuan Li, Lili Jiang, Wanfei Shan, Cheng Hu, Aolin Deng, Zhe Ying, Lele Wang, Yiran Zhang, Hans A Bechtel, Michael C Martin, Takashi Taniguchi, Kenji Watanabe, Weidong Luo, Feng Wang, Zhiwen Shi
Strain plays an important role in condensed matter physics and materials science because it can strongly modify the mechanical, electrical, and optical properties of a material, and even induce a structural phase transition. Strain effects are especially interesting in atomically thin two-dimensional (2D) materials, where unusually large strain can be achieved without breaking them. Measuring the strain distribution in 2D materials at the nanometer scale is therefore greatly important but is extremely challenging experimentally...
February 19, 2019: Nano Letters
https://read.qxmd.com/read/30779304/molecular-characterization-and-expression-of-sensory-neuron-membrane-proteins-snmps-in-the-parasitoid-microplitis-mediator-hymenoptera-braconidae
#20
Shuang Shan, Shan-Ning Wang, Xuan Song, Adel Khashaveh, Zi-Yun Lu, Khalid Hussain Dhiloo, Rui-Jun Li, Xi-Wu Gao, Yong-Jun Zhang
Sensory neuron membrane proteins (SNMPs), homologs of the human fatty acid transport protein CD36 family, are observed to play a significant role in chemoreception especially in detecting sex-pheromone in Drosophila and some lepidopteran species. In the current study, two full-length SNMP transcripts, MmedSNMP1 and MmedSNMP2, were identified in the parasitoid Microplitis mediator (Hymenoptera: Braconidae). Quantitative real-time PCR (qRT-PCR) analysis showed that the expression of MmedSNMP1 was significantly higher in antennae than in other tissues of both sexes...
February 19, 2019: Insect Science
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